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Search Results: 1 - 10 of 8728 matches for " Yulin Deng "
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Microfluidic Approaches for Cancer Cell Separation: Review  [PDF]
Omer Osman Saeed, Rui Li, Yulin Deng
Journal of Biomedical Science and Engineering (JBiSE) , 2014, DOI: 10.4236/jbise.2014.712098
Abstract: This article reviews the recent developments in microfluidic technologies for in vitro cancer diagnosis. We summarize the working principles and experimental results of microfluidic platforms for cancer cell detection, and separation based on magnetic activated micro-sorting, and differences in cellular biophysics (e.g., cell size and dielectrophoresis (DEP)).
Oversea Background Executive, Risk-Taking and Corporate Performance  [PDF]
Yulin Guo
Modern Economy (ME) , 2018, DOI: 10.4236/me.2018.912139
Abstract: Overseas background executives are becoming more and more important to enterprises. By analyzing the data of A-share listed companies in China from 2011 to 2017, this paper finds that the existence of overseas background executives is conducive to the improvement of corporate performance. And senior managers with overseas working experience and core managers with overseas experience in enterprises can play a more important role. At the same time, the study shows that risk-taking plays a mediating role in the impact of overseas executives on corporate performance. And only when the external institutional environment is good, can overseas executives play their role.
Effects of cadmium, 17β-estradiol and their interaction in the male Chinese loach (Misgurnus anguillicaudatus)
XueFei Lü,FeiYuan Liu,XiaoPing Zhou,QunFang Zhou,YuLin Deng
Chinese Science Bulletin , 2012, DOI: 10.1007/s11434-011-4708-4
Abstract: To assess the interaction effect between cadmium (Cd) and 17β-estradiol (E2), male Chinese loaches (Misgurnus anguillicaudatus) were exposed to E2 (1 μg/L) and Cd (50 or 500 μg/L) alone and in combination using a semi-static waterborne exposure system. The effects of E2 on the accumulation and distribution of Cd, as well as the effects of Cd on vitellogenin (Vtg) synthesis induced by E2, were investigated. Cd mainly accumulated in the kidneys, liver, intestines, and gills, with little amounts in muscles, bones, and gonads. Co-exposure with E2 did not change the main targets for Cd. E2 could induce Vtg synthesis in male Chinese loaches, and co-exposure with 50 or 500 μg/L Cd could inhibit the Vtg induced by 1 μg/L E2. Compared with the results reported in the literature, it can be concluded that factors such as fish species, Cd dosage, and manner of exposure might make contributions to the interaction between Cd and E2. Our results also suggested that male Chinese loaches are susceptible to Cd, and can be recommended as a potential sentinel species to study the ecotoxicology of heavy metals.
4-(4-Bromophenyl)-5-oxo-1,2,3,4,5,6,7,8-octahydroquinazoline-2-thione
Min Xie,Changquan Deng,Jie Zheng,Yulin Zhu
Acta Crystallographica Section E , 2009, DOI: 10.1107/s1600536809028761
Abstract: The title compound, C14H13BrN2OS, was synthesized from the multicomponent reaction between thiourea, 4-bromobenzaldehyde and cyclohexane-1,3-dione. The crystal packing is stabilized by intermolecular N—H...O, N—H...S, C—H...O and C—H...S hydrogen bonds. Br...O interactions [3.183 (3) ] are also observed in the crystal structure.
Optimizations of Conditions for Maximum Recovery of Astragalin from Thesium chinense Turcz
Zahida Parveen,Yulin Deng,Muhammad Khalid Saeed,Rongji Dai
Journal of Applied Sciences , 2006,
Abstract: Astragalin, one of the flavonoid extracted from plants is increasingly in demand in food and pharmaceutical industries due to its various biological and physiological activities including antioxidation, antiallergy, anti-inflammation and anti-hepatoptoxic. The whole plant of Thesium chinense Turcz is a major source of astragalin. This study developed a low-cost process encompassing the efficient extraction, fractionation, isolation and recrystallization to obtain high-purity astragalin from Thesium chinense and it could improve the economic utilization of this plant. In this study plant was extracted with 80% ethanol for 3 h and extract was fractionated on AB-8 (styrene based copolymer) with water, 20, 40 and 80% aqueous ethanol. Astragalin was isolated by silica gel column and purified by recrystalization with methanol. These conditions resulted 90% recovery of Astragalin with 95% purity.
Studies on the Chemical Constituents of Torreya grandis Fort. Ex Lindl
Muhammad Khalid Saeed,Yulin Deng,Zahida Parveen,Rongji Dai
Journal of Applied Sciences , 2007,
Abstract: Natural products play a very important role in the medicine of the world’s population. Therefore, it is important that natural product chemistry continues to explore natural resources in search of new natural products. The phytochemical analysis of Torreya grandis leaves led to the isolation of five compounds using column chromatography, Preparative High-Performance Liquid Chromatography (PHPLC) and Thin Layer Chromatography (TLC). The structures elucidation of the isolated compounds were performed by spectroscopic techniques (1H NMR, LC-MS) and identified as kaempferol (1) acacetin (2), chrysoeriol (3), wogonin (4) and dibutyl phthalate (DBP) (5). Among these, compounds 1 and 5 have not been reported from this plant.
SpaceLifeScienceofChinain2013
Lei,Runhong,Zhou,Guangming,Ma,Hong,Zhuang,Fengyuan,Deng,Yulin
空间科学学报 , 2014, DOI: 10.11728/cjss2014.05.747
Abstract: Inthepasttwoyears,spacelifescienceresearchinChinaischaracterizedbyawideareaofbasicresearchesforprovidingfoundationforthefutureChinaSpaceStation.Theeffectofmicrogravityandradiationwasfurtherstudiedfromphysiologyphenomenatothelevelofbio-moleculemechanisms.Chinesespacelifescienceismaturinginaneweraofcomprehensivedevelopment.Here,wereviewandsummarizeresearchesonspacelifescienceswhichwerecontributedbyChinesescientists.
A MAC Scheme with QoS Guarantee for MANETs  [PDF]
Yanbin YANG, Yulin WEI
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2009, DOI: 10.4236/ijcns.2009.28088
Abstract: IEEE 802.11 distributed coordination function (DCF) can alleviate the collision and hidden station problem, but it doesn’t differentiate traffic categories (TC). Therefore, it can’t provide sufficient QoS support for different traffic categories. Recently, a new contention-based enhanced distributed channel access (EDCA) scheme was proposed which provides a probabilistic QoS support. In this paper, an adaptive EDCA scheme with QoS guarantee for mobile ad hoc networks (MANETs) is proposed. In this scheme, the EDCA scheme and the token bucket algorithm (TBA) are combined to adjust the contention window (CW). Our scheme provides the traffic differentiation.
CD154 and IL-2 Signaling of CD4+ T Cells Play a Critical Role in Multiple Phases of CD8+ CTL Responses Following Adenovirus Vaccination
Channakeshava Sokke Umeshappa, Roopa Hebbandi Nanjundappa, Yufeng Xie, Andrew Freywald, Yulin Deng, Hong Ma, Jim Xiang
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0047004
Abstract: Adenoviral (AdV) vectors represent most commonly utilized viral vaccines in clinical studies. While the role of CD8+ cytotoxic T lymphocyte (CTL) responses in mediating AdV-induced protection is well understood, the involvement of CD4+ T cell-provided signals in the development of functional CD8+ CTL responses remain unclear. To explore CD4+ T helper signals required for AdVova-stimulated CTL responses, we established an adoptive transfer system by transferring CD4+ T cells derived from various knock out and transgenic mice into wild-type and/or CD4-deficient animals, followed by immunizing with recombinant ovalbumin (OVA)-expressing AdVova vector. Without CD4+ T help, both primary and memory CTL responses were greatly reduced in this model, and were associated with increased PD-1 expression. The provision of OVA-specific CD4+ T help in CD4+ T cell-deficient mice restored AdVova-induced primary CTL responses, and supported survival and recall responses of AdVova-stimulated memory CTLs. These effects were specifically mediated by CD4+ T cell-produced IL-2 and CD154 signals. Adoptive transfer of “helped” or “unhelped” effector and memory CTLs into na?ve CD4+ T cell-deficient or -sufficient mice also revealed an additional role for polyclonal CD4+ T cell environment in the survival of AdVova-stimulated CTLs, partially explaining the extension of CTL contraction phase. Finally, during recall responses, CD4+ T cell environment, particularly involving memory CD4+ T cells, greatly enhanced expansion of memory CTLs. Collectively, our data strongly suggest a critical role for CD4+ T help in multiple phases of AdV-stimulated CTL responses, and could partially explain certain failures in AdV-based immunization trials targeting malignant tumors and chronic diseases that are often associated with compromised CD4+ T cell population and function.
Preparation and evaluation of an enzymatic microreactor based on HILIC matrix for digestion and identification of proteins
ShanShan Wang,Qin Li,XueFei Lü,Tong Liu,WeiBo Zhang,LiNa Geng,YuLin Deng
Chinese Science Bulletin , 2010, DOI: 10.1007/s11434-010-0060-3
Abstract: In the present study, a new enzymatic microreactor is developed by immobilizing trypsin on the matrix-HILIC (hydrophilic interaction chromatography). The influences of different types of buffer solutions (borate, Tris·HCl, and phosphate), their concentrations and pH values on the immobilizing rate and the activity of immobilized trypsin were investigated. The optimal condition for off-line immobilization of trypsin on matix-HILIC was Tris·HCl buffer (20 mmol/L, pH 8.0), and then, under the optimal condition, an enzymatic microreactor was prepared by trypsin dynamically immobilized on HILIC matrix which was packed in a Peeksil column. It can be found that the microreactor possessed high hydrolytic activity according to the hydrolysis results of N-α-benzoyl-DL-arginine P-nitroanilide (BAPNA), a substrate of trypsin. Moreover, bovine serum albumin (BSA), cytochrome C and myoglobin as standard proteins were chosen to characterize the enzymolysis of the microreactor demonstrating the high enzymolysis efficiency by this enzymatic microreactor. Besides, the deactivated trypsin can be easily eluted from the matrix-HILIC to re-immobilize trysin, which is highly cost-effective in the experiment. All the results show that the new enzymatic microreactor associated with HPLC-MS techniques can realize online enzymolysis of proteins, and the time to analyze and identify the proteins is greatly shortened.
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