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Search Results: 1 - 10 of 174162 matches for " Yu-Jang Li "
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Discovery of New Stilbene Antioxidants of the Bio-Elicited Peanut Sprout Powder (BPSP) and Longevity Extension of Mice Fed with BPSP-Supplemented Diets  [PDF]
Robin Y.-Y. Chiou, Po-Chang Chiu, Ju-Chun Chang, Yu-Jang Li, Chia-Wen Hsieh, Jin-Yi Wu, Shu-Mei Lin, Yun-Lian Lin, Brian B.-C. Weng
Food and Nutrition Sciences (FNS) , 2017, DOI: 10.4236/fns.2017.81010
Abstract: Biosynthesis of peanut stilbenes, including resveratrol as the secondary metabolites, could be enhanced by subjecting the kernels to germination and wound-stress. Investigations of the bio-elicited peanut sprout powder (BPSP) addressed on characterization of the comprising stilbenes and effectiveness in longevity extension deserves intensive research. In this study, peanut kernels were subjected to germination and wound-stress in preparation of BPSP. The methanol extracts of BPSP were medium pressure liquid chromatographic (MPLC) fractionated and semi-preparative HPLC recovered and followed by instrumental identification and biological activity determinations of the isolated stilbenes. In longevity experiments, 16 female 11-mon-old BALB/c mice and both genders of 12-mon-old ICR mice were daily fed with BPSP supplemented diets at doses of 0, 0.1 and 0.5 g BPSP/kg bw for 750 and 762 days, respectively. Based on chemical characterization, enriched quantity of stilbenes in the BPSP up to ca. 1% (w/w) was detected. Two new stilbene compounds, namely, 4, 5’-dihydroxy-6’’-hydroxymethyl, 6’’-methylpyrano [2’’, 3’’: 3’, 4’] stilbene and 3, 4, 5’-trihydroxy-6’’, 6’’-dimethylpyrano [2’’, 3’’: 3’, 4’]stilbene along with 5 known stilbenes were isolated. The 7 stilbenes exhibited potent antioxidative and antiglycative activities and varied with structure-activity nature. Based on the resultant survival curves and average lifespans of both mouse models, basal diets supplemented with BPSP are effective to extend mouse longevity by a dose dependent manner.
The Asset Pricing System  [PDF]
Yi-Jang Yu
Modern Economy (ME) , 2012, DOI: 10.4236/me.2012.35062
Abstract: Mainstream asset pricing models are all inappropriate when they consistently insist on applying one single model to deal with a reality filled with different aspects of asset pricing. In addition, those models also treat the right environ-ment variable too lightly hence can not rightly do the job of asset pricing. In this study, based on the portfolio theory and the principle of supply and demand, a more reasonable asset pricing system including five different models will be suggested to provide a necessary function of automatic price stabilization and to better serve our financial market.
Option Pricing with Economic Feasibility  [PDF]
Yi-Jang Yu
Modern Economy (ME) , 2013, DOI: 10.4236/me.2013.41009
Abstract:

Asset pricing under the certainty equivalent approach framework always raises the current value of the asset with the riskless rate first, followed immediately by risk adjustments. Clearly, this type of arrangement does not apply to assets that are expecting to lose values if it were to adhere to feasible economic reasoning. By using the put-call parity relationship and its underlying law of no arbitrage, the needed expected rates of return for the job of option pricing can thus be obtained. This study suggests a new model in old fashion, which can better satisfy the empirical criticism of the Black-Scholes option pricing model.

Economic Natural Laws and Economics  [PDF]
Yi-Jang Yu
Modern Economy (ME) , 2015, DOI: 10.4236/me.2015.61002
Abstract: Human activity causes extensive destruction to nature. However, nature is necessary to us; continuing to damage it regardless of consequence is unwise. Microeconomic and macroeconomic natural laws were introduced by [1], but the global economy is not operating in compliance with the microeconomic natural law. If ignorance of the importance and feasibility of the microeconomic natural law is the reason for the global economy to not adhere to it, then more explanations must be provided. The current mainstream school of economics has already resolved the threat of resource scarcity; therefore, reinforcing the shortage of this school is necessary to undertake the new mission of addressing the threat of environmental destruction.
Microeconomic Natural Law, Portfolio Principle and Economics Textbooks  [PDF]
Yi-Jang Yu
Modern Economy (ME) , 2016, DOI: 10.4236/me.2016.75063
Abstract: This study explains that, after combining the microeconomic natural law with the portfolio principle and a few bases in general economic analyses, the capability of managing all fundamental challenges in business operation, financing, and marketing can be directly established in economics textbooks. It is impossible to cover all critical topics; however, restoring economics as the foundation of all major disciplines for economic management can still be practically achieved. More crucially, by endogenizing the economic environment, such new economic textbooks can guide the chaotic economic world back to its normal conditions. The illustrated methodology is still far from perfect because the real synergistic effects cannot be quantitatively studied, and natural and social environments are still treated as exogenous factors in the analytical framework. Clearly, economics still has numerous challenges to overcome.
Beyond the No Free Lunch Principle: A New Combination of Arbitrage and Investment  [PDF]
Yi-Jang Yu
Modern Economy (ME) , 2018, DOI: 10.4236/me.2018.94046
Abstract: In the financial market, within both extremities of asset investment and arbitrage, there are sufficient rooms to contain something else other than speculation. The first aim of this study is thus to introduce a new sector which although cannot violate the common sense of “no free lunch” as can arbitrage, still is capable of surmounting general beliefs about the trade-off between risk and return that accompanies speculation. The second aim of this study is intended to reduce the ingredients of unfair games in the financial market.
Adding a New Category of “Individual vs System” to the Economics  [PDF]
Yi-Jang Yu
Modern Economy (ME) , 2018, DOI: 10.4236/me.2018.911117
Abstract: After the industrial revolution, the long-term effort of resolving the threat of resource scarcity was accomplished globally in the 1950s. However, the threat of environmental destruction was, and still is, accumulating along the way. As mainstream economics is the main culprit of environmental destruction, it cannot be expected also to be the correct solution. Accordingly, it is suggested that a new category of “individual vs system” should be added to the economics. As the inability of the mainstream microeconomics to endogenise the environmental variable and to construct the right foundation for microeconomic analyses can be remedied based on the microeconomic natural laws within the new category, so too, can the incapability to resolve the threat of environmental destruction from the mainstream macroeconomics be reversed based on the macroeconomic natural laws also within the new category.
Investigation of Effective Plasma Frequencies in One-Dimensional Plasma Photonic Crystals
Chien-Jang Wu;Tzong-Jer Yang;Chang Ching Li;Pei Yu Wu
PIER , 2012, DOI: 10.2528/PIER12030505
Abstract: In this work, a detailed investigation on the effective plasma frequency for one-dimensional binary and ternary plasma-dielectric photonic crystals is made. We extract and then analyze the effective plasma frequency from the calculated photonic band structures at distinct conditions. In the binary photonic crystal, it is found that in a photonic crystal is usually smaller than the plasma frequency of a bulk plasma system. will increase when the electron concentration in the plasma layer increases. It also increases as the thickness of the plasma layer increases, but decreases with the increase in the thickness of dielectric layer. In the ternary photonic crystal, is shown to be decreased compared to that of in the binary one. Our results are compared with the analytical expression for derived from the concept of effective medium. Fairly good consistence has been obtained for both results. Additionally, a discussion on the effect of loss on is also given. The study is limited to the case of normal incidence.
β-Cell Regeneration Mediated by Human Bone Marrow Mesenchymal Stem Cells
Anna Milanesi, Jang-Won Lee, Zhenhua Li, Stefano Da Sacco, Valentina Villani, Vanessa Cervantes, Laura Perin, John S. Yu
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0042177
Abstract: Bone marrow mesenchymal stem cells (BMSCs) have been shown to ameliorate diabetes in animal models. The mechanism, however, remains largely unknown. An unanswered question is whether BMSCs are able to differentiate into β-cells in vivo, or whether BMSCs are able to mediate recovery and/or regeneration of endogenous β-cells. Here we examined these questions by testing the ability of hBMSCs genetically modified to transiently express vascular endothelial growth factor (VEGF) or pancreatic-duodenal homeobox 1 (PDX1) to reverse diabetes and whether these cells were differentiated into β-cells or mediated recovery through alternative mechanisms. Human BMSCs expressing VEGF and PDX1 reversed hyperglycemia in more than half of the diabetic mice and induced overall improved survival and weight maintenance in all mice. Recovery was sustained only in the mice treated with hBMSCs-VEGF. However, de novo β-cell differentiation from human cells was observed in mice in both cases, treated with either hBMSCs-VEGF or hBMSCs- PDX1, confirmed by detectable level of serum human insulin. Sustained reversion of diabetes mediated by hBMSCs-VEGF was secondary to endogenous β-cell regeneration and correlated with activation of the insulin/IGF receptor signaling pathway involved in maintaining β-cell mass and function. Our study demonstrated the possible benefit of hBMSCs for the treatment of insulin-dependent diabetes and gives new insight into the mechanism of β-cell recovery after injury mediated by hBMSC therapy.
Using Unsupervised Patterns to Extract Gene Regulation Relationships for Network Construction
Yi-Tsung Tang,Shuo-Jang Li,Hung-Yu Kao,Shaw-Jenq Tsai,Hei-Chia Wang
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0019633
Abstract: The gene expression is usually described in the literature as a transcription factor X that regulates the target gene Y. Previously, some studies discovered gene regulations by using information from the biomedical literature and most of them require effort of human annotators to build the training dataset. Moreover, the large amount of textual knowledge recorded in the biomedical literature grows very rapidly, and the creation of manual patterns from literatures becomes more difficult. There is an increasing need to automate the process of establishing patterns.
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