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Search Results: 1 - 10 of 34524 matches for " Yongchun ZHOU "
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Electromagnetic Study of MW-Class HTS Wind Turbine Generators  [PDF]
Yongchun Liang
Energy and Power Engineering (EPE) , 2013, DOI: 10.4236/epe.2013.54B072
Abstract: High temperature superconductor (HTS) technology enables a significant reduction in the size and weight of MW-class generators for direct-drive wind turbine systems and reduce the cost of clean energy relative to conventional copper an permanent-magnet-based generators and gearbox. Using MAXWELL, we studied MW class superconducting synchronous machines. By comparison the weight, we concluded that HTS wind turbine with rotor iron is the heaviest and HTS wind turbine without rotor iron and stator teeth is the lightest. By comparison the flux density, HTS wind turbine without rotor iron is the least and HTS wind turbine without rotor iron and stator teeth is the largest. By comparison the cost, HTS wind turbine with rotor iron is the highest and the other two is almost the same. HTS wind turbine without rotor iron and stator teeth is the best type.
Scheme of Combined Marker Based Watershed for Infrared Image Segmentation
Xiangzhi Bai,Fugen Zhou,Yongchun Xie,Ting Jin
International Journal of Distributed Sensor Networks , 2009, DOI: 10.1080/15501320802558464
Abstract: To segment infrared dim target, a combined marker based watershed algorithm is proposed, analysed, and verified.
Establishment of Orthotopic Lewis Lung Cancer Model in Mouse
Xin LIU,Zhiping WU,Shuguang ZUO,Yongchun ZHOU
Chinese Journal of Lung Cancer , 2010,
Abstract: Background and objective The mouse lung cancer orthotopic model includes spontaneous lung cancer model and endotracheal transplanted model, and etc. The spontaneous lung cancer needs longer time and does not ensure the rate of the generation of the tumor; as for endotracheal transplanted model, the position and size of the tumor are instable. In this study, the 3LL cell line was orthotopically transplanted into the lung of the C57BL/6 mice, compare to the heterotopic model, to discuss their stability and transfer-characteristics. And this study was also to optimize the method of establishing lung cancer orthotopic animal model. Methods Different quantity of 3LL cells were inoculated into the left oxter of C57BL/6 mice to establish the heterotopic model; or suspended with Matrigel then inoculated into the left lung of C57BL/6 mice to establish orthotopic model. The survival-time of the mice was examined. The tissue was collected for the subsequent histology assay after euthanizing the mice. Microvessels density (MVD) was observed and counted by immunohistological chemistry. CD44v was detected by flow cytometry. Results TTumor-form-rate of the heterotopic group were 100%, 66.7%, 16.7%, respectively, and had no macroscopic transfer. Tumor-form-rate of the orthotopic group were 100%, 100%, 83.3%, respectively, and had widespread transfer in contralateral chest and the lung. The median survival time of the orthotopic group ( 38, 35, 23 days) were less than the heterotopic group (82, 72, 50 days). MVD of the orthotopic group (120.2±9.73) was higher than the heterotopic group (92.6±7.12). The expression of CD44v of orthotopic (26.46± 1.56)% was higher than the heterotopic group (23.13±1.02)%. Conclusion The lung cancer orthotopic model which established by 3LL cells transplanted into the lung of the mice is simple, dependable, repeatable and has stronger transfer characteristics than the heterotopic model.
Establishment of Orthotopic Xuanwei Lung Cancer SCID Mouse Model and Analysis of Biological Properties
Yongchun ZHOU,Yan CHEN,Xicai WANG,Xin LIU
Chinese Journal of Lung Cancer , 2012, DOI: 10.3779/j.issn.1009-3419.2012.08.01
Abstract: Background and objective The incidence of Xuanwei lung cancer ranks first in China, and its pathogenesis requires in-depth investigation. This study aims to establish an orthotopic Xuanwei lung cancer severe combined immunodeficiency (SCID) mouse model and to provide a basic experimental platform for further study. Methods The Xuanwei lung cancer cell line XWLC-05 was inoculated into the lung tissue of SCID mice in high and low doses. The tumor formation rates, tumor characteristics, spontaneous metastases, and survival times of the mice were observed, taking a subcutaneously transplanted tumor as control. Results The tumor formation rates of the orthotopic transplantation of lung cancer cells in high and low doses were 81% and 83%, respectively, among which mice in the high-dose group appeared cachectic on day 13. Extensive invasion and adhesion were observed in the contralateral lung and thoracic cavity, but no distant metastasis was exhibited. Mice with low-dose cells in the orthotopic transplantation group appeared cachectic and distant metastasis occurred on day 25. The tumor formation rates in the subcutaneous inoculation group by the high and low doses of cells were 100% and 94.5%, respectively, and no distant metastasis was observed. The rate of metastasis within the orthotopic transplantation group and between the orthotopic and subcutaneous inoculation groups showed a significant difference (P<0.05). A significant difference was indicated by the survival rate within and between the groups (P<0.001). Conclusion We successfully established an orthotopic XWLC SCID mouse model, which lays the foundation for a more in-depth study.
Review of double mood stabilizer treatments for bipolar disorder in China  [PDF]
Weidong Jin, Maria Uscinska, Yongchun Ma
Open Journal of Psychiatry (OJPsych) , 2014, DOI: 10.4236/ojpsych.2014.41001
Abstract:

Background: Although treatment guidelines for bipolar disorder in many countries commonly include lithium carbonate joint with sodium valproate, this combination is not effective for all patients. Moreover, some adverse reactions related to this treatment, neurotoxicity and interaction with other drugs justify and call for a new reviewing of the issue. Methods: Evidence base for the interactions of combined drugs, the metabolic features, action mechanism, efficacy and side effects of these treatment combinations were reviewed. Considerable attention was given to the relationship of the mutual action of these drugs with their clinical efficacy but also their side effects. Results: The efficacy of combination therapy of lithium with valproate for treatment and prevention of mania were superior to monotherapy of lithium or valproate. Conclusion: Double mood stabilizer therapy is the best relative treatment for patients with bipolar disorder, especially mania and related episodes.

Study of the Changes on Tree Shrew Bronchial Epithelium ?Induced by Xuanwei Bituminous Coal Dust
Xiaobo CHEN, Meng HE, Guangjian LI, Yongchun ZHOU, Guangqiang ZHAO, Yujie LEI, Kaiyun YANG, Linwei TIAN, Yunchao HUANG
- , 2015, DOI: : 10.3779/j.issn.1009-3419.2015.08.01
Abstract: Background and objective Lung cancer is the type of cancer with the highest incidence and mortality in numerous countries and regions. Establishing an appropriate animal model that can be used to simulate lung cancer etiology, pathogenesis, and similar processes, is urgent. We explore the feasibility of establishing a lung cancer model induced by Xuanwei bituminous coal dust PM10 (particulate matter with diameters of 10 μm or less), which affects bronchial epithelium of tree shrews. Methods The neck skin of adult tree shrews is dissected, and the thyroid cartilage is fully exposed. Subsequently, the weak part at the top of the thyroid cartilage is treated with intratracheal agents by perfusion via a special infusion needle puncture method. Regular X-ray examination and lung tissue biopsy were performed on the sacrificed animals to observe changes in pulmonary imaging and bronchial epithelial cells after perfusion of Xuanwei bituminous coal dust PM 10. Results The tree shrews of the experimental group (exposed to bituminous coal dust) died in a week after perfusion with PM10, whereas no animal died until the end of the experiment in the blank control and the solvent control groups. Sections of lung tissue biopsy of the regularly killed tree shrews were stained with hematoxylin and eosin. The lung tissues of tree shrews in the experimental group showed a serial changes caused by bronchial epithelial hyperplasia, such as squamous metaplasia, dysplasia, and early invasive carcinoma, whereas no significant pathological changes were observed in the blank control and solvent control groups. Conclusion Endotracheal infusion of Xuanwei bituminous coal dust PM10 induces lung cancer in tree shrews. Thus, the lung cancer model was established.
Experimental studies on generation kinetics of n-alkanes in petroleum
Jinzhong Liu,Yongchun Tang
Chinese Science Bulletin , 1997, DOI: 10.1007/BF02882624
Abstract: Because equipment condition was limited, kinetics of methane, which is one of the most important component in petroleum exploration, is not discussed in this note. Our further work will focus on kinetics of methane through a modified MCT-GC set.
Kinetics of petroleum generation determined from multiple cold trap pyrolysis gas chromatography
Jinzhong Liu,Yongchun Tang
Chinese Science Bulletin , 1997, DOI: 10.1007/BF02882450
Abstract:
Kinetics of early methane generation from Green River shale
Jinzhong Liu,Yongchun Tang
Chinese Science Bulletin , 1998, DOI: 10.1007/BF02883470
Abstract: During oil/gas exploration in an area, there is a question as to whether methane in the strata was generatedin situ mainly by thermal degradation of local organic matter. The key to the question is whether the kerogen could produce methane of more than 80 mL/g TOC, when its Ro increased from initial (0.36%) to current value of 0.70% during thermal evolution. The authors have made efforts to answer this question by the kinetics method. First, a series of pyrolysis experiments were carried out to obtain data of methane yield and Ro evolution, from which kinetic parameters of methane and Ro were derived; then these parameters were extrapolated to the geological condition and finally, a methane yield, 96 mL/g TOC, was predicted. The result suggests that from the view of hydrocarbon generation, methane in the seam should be from thermal degradation of local kerogen.
Sliding Mode Control for Uncertain Chaotic Systems with Nonlinear Inputs
Yongchun Liu,Da Lin
Mechanical Engineering Research , 2012, DOI: 10.5539/mer.v2n1p1
Abstract: A sliding mode control design for a class of uncertain chaotic systems subject to sector nonlinear inputs and dead zone is considered in this paper. It is guaranteed that, under the proposed control law, chaotic systems can asymptotically drive the system orbits to arbitrarily desired trajectories even with both uncertainties and input nonlinearities. However, in the sliding mode, the investigated uncertain chaotic system with nonlinear input still possesses advantages of fast response, good transient performance and insensitive to the parameter uncertainties and external disturbances as the systems with linear input. Finally, the Duffing-Holmes chaotic system and the multi-scroll chaotic system are used as an illustrative example to demonstrate the effectiveness of the proposed control scheme.
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