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Search Results: 1 - 10 of 149763 matches for " Yokogawa H "
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Rationality of Moduli Spaces of Parabolic Bundles
H. U. Boden,K. Yokogawa
Mathematics , 1996,
Abstract: The moduli space of parabolic bundles with fixed determinant over a smooth curve of genus greater than one is proved to be rational whenever one of the multiplicities associated to the quasi-parabolic structure is equal to one. It follows that if rank and degree are coprime, the moduli space of vector bundles is stably rational, and the bound obtained on the level is strong enough to conclude rationality in many cases.
Moduli Spaces of Parabolic Higgs Bundles and Parabolic K(D) Pairs over Smooth Curves: I
H. U. Boden,K. Yokogawa
Mathematics , 1996,
Abstract: This paper concerns the moduli spaces of rank two parabolic Higgs bundles and parabolic K(D) pairs over a smooth curve. Precisely which parabolic bundles occur in stable K(D), pairs and stable Higgs bundles is determined. Using Morse theory, the moduli space of parabolic Higgs bundles is shown to be a non-compact, connected, simply connected manifold, and a computation of its Poincar\'e polynomial is given.
A sliding technique to load thin endothelial donor lamella onto Busin glide for Descemet-stripping automated endothelial keratoplasty
Kobayashi A, Yokogawa H, Sugiyama K
Clinical Ophthalmology , 2012, DOI: http://dx.doi.org/10.2147/OPTH.S34197
Abstract: sliding technique to load thin endothelial donor lamella onto Busin glide for Descemet-stripping automated endothelial keratoplasty Methodology (1314) Total Article Views Authors: Kobayashi A, Yokogawa H, Sugiyama K Published Date August 2012 Volume 2012:6 Pages 1229 - 1231 DOI: http://dx.doi.org/10.2147/OPTH.S34197 Received: 24 May 2012 Accepted: 21 June 2012 Published: 02 August 2012 Akira Kobayashi, Hideaki Yokogawa, Kazuhisa Sugiyama Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan Abstract: We describe a modified technique for loading donor corneal endothelial lamella onto a Busin glide without causing wrinkles, as part of the procedure of Descemet-stripping automated endothelial keratoplasty. Briefly, after punching out a composite of the donor-endothelial lamella and a microkeratome-dissected cap, several drops of dispersive ophthalmic viscosurgical device are placed onto the endothelial surface. The Busin glide surface is then wetted with several drops of balanced salt solution. After the composite is transferred onto the Busin glide, hydrodissection of the potential space between the donor-endothelial lamella and the microkeratome-dissected cap is carefully performed to enable smooth detachment of these two lamellae. Whereas simply dragging the donor-endothelial lamella directly onto the glide can cause wrinkling or folding of the donor lamella, this technique enables smooth detachment of the composite without wrinkle or fold formation, and results in less endothelial cell damage.
In vivo laser confocal microscopy findings in patients with map-dot-fingerprint (epithelial basement membrane) dystrophy
Kobayashi A, Yokogawa H, Sugiyama K
Clinical Ophthalmology , 2012, DOI: http://dx.doi.org/10.2147/OPTH.S34196
Abstract: vivo laser confocal microscopy findings in patients with map-dot-fingerprint (epithelial basement membrane) dystrophy Case Series (1491) Total Article Views Authors: Kobayashi A, Yokogawa H, Sugiyama K Published Date July 2012 Volume 2012:6 Pages 1187 - 1190 DOI: http://dx.doi.org/10.2147/OPTH.S34196 Received: 24 May 2012 Accepted: 12 June 2012 Published: 27 July 2012 Akira Kobayashi, Hideaki Yokogawa, Kazuhisa Sugiyama Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan Background: The purpose of this study was to investigate pathological changes of the corneal cell layer in patients with map-dot-fingerprint (epithelial basement membrane) dystrophy by in vivo laser corneal confocal microscopy. Methods: Two patients were evaluated using a cornea-specific in vivo laser scanning confocal microscope (Heidelberg Retina Tomograph 2 Rostock Cornea Module, HRT 2-RCM). The affected corneal areas of both patients were examined. Image analysis was performed to identify corneal epithelial and stromal deposits correlated with this dystrophy. Results: Variously shaped (linear, multilaminar, curvilinear, ring-shape, geographic) highly reflective materials were observed in the “map” area, mainly in the basal epithelial cell layer. In “fingerprint” lesions, multiple linear and curvilinear hyporeflective lines were observed. Additionally, in the affected corneas, infiltration of possible Langerhans cells and other inflammatory cells was observed as highly reflective Langerhans cell-like or dot images. Finally, needle-shaped materials were observed in one patient. Conclusion: HRT 2-RCM laser confocal microscopy is capable of identifying corneal microstructural changes related to map-dot-fingerprint corneal dystrophy in vivo. The technique may be useful in elucidating the pathogenesis and natural course of map-dot-fingerprint corneal dystrophy and other similar basement membrane abnormalities.
A sliding technique to load thin endothelial donor lamella onto Busin glide for Descemet-stripping automated endothelial keratoplasty
Kobayashi A,Yokogawa H,Sugiyama K
Clinical Ophthalmology , 2012,
Abstract: Akira Kobayashi, Hideaki Yokogawa, Kazuhisa SugiyamaDepartment of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, JapanAbstract: We describe a modified technique for loading donor corneal endothelial lamella onto a Busin glide without causing wrinkles, as part of the procedure of Descemet-stripping automated endothelial keratoplasty. Briefly, after punching out a composite of the donor-endothelial lamella and a microkeratome-dissected cap, several drops of dispersive ophthalmic viscosurgical device are placed onto the endothelial surface. The Busin glide surface is then wetted with several drops of balanced salt solution. After the composite is transferred onto the Busin glide, hydrodissection of the potential space between the donor-endothelial lamella and the microkeratome-dissected cap is carefully performed to enable smooth detachment of these two lamellae. Whereas simply dragging the donor-endothelial lamella directly onto the glide can cause wrinkling or folding of the donor lamella, this technique enables smooth detachment of the composite without wrinkle or fold formation, and results in less endothelial cell damage.Keywords: DSAEK, Busin glide, endothelial keratoplasty
In vivo laser confocal microscopy findings in patients with map-dot-fingerprint (epithelial basement membrane) dystrophy
Kobayashi A,Yokogawa H,Sugiyama K
Clinical Ophthalmology , 2012,
Abstract: Akira Kobayashi, Hideaki Yokogawa, Kazuhisa SugiyamaDepartment of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, JapanBackground: The purpose of this study was to investigate pathological changes of the corneal cell layer in patients with map-dot-fingerprint (epithelial basement membrane) dystrophy by in vivo laser corneal confocal microscopy.Methods: Two patients were evaluated using a cornea-specific in vivo laser scanning confocal microscope (Heidelberg Retina Tomograph 2 Rostock Cornea Module, HRT 2-RCM). The affected corneal areas of both patients were examined. Image analysis was performed to identify corneal epithelial and stromal deposits correlated with this dystrophy.Results: Variously shaped (linear, multilaminar, curvilinear, ring-shape, geographic) highly reflective materials were observed in the “map” area, mainly in the basal epithelial cell layer. In “fingerprint” lesions, multiple linear and curvilinear hyporeflective lines were observed. Additionally, in the affected corneas, infiltration of possible Langerhans cells and other inflammatory cells was observed as highly reflective Langerhans cell-like or dot images. Finally, needle-shaped materials were observed in one patient.Conclusion: HRT 2-RCM laser confocal microscopy is capable of identifying corneal microstructural changes related to map-dot-fingerprint corneal dystrophy in vivo. The technique may be useful in elucidating the pathogenesis and natural course of map-dot-fingerprint corneal dystrophy and other similar basement membrane abnormalities.Keywords: cornea, confocal microscopy, map-dot-fingerprint dystrophy, epithelial basement membrane dystrophy, Heidelberg Retina Tomograph 2 Rostock Cornea Module (HRT 2-RCM)
Clinical features of single and repeated globe rupture after penetrating keratoplasty
Murata N, Yokogawa H, Kobayashi A, Yamazaki N, Sugiyama K
Clinical Ophthalmology , 2013, DOI: http://dx.doi.org/10.2147/OPTH.S42117
Abstract: ical features of single and repeated globe rupture after penetrating keratoplasty Case Series (492) Total Article Views Authors: Murata N, Yokogawa H, Kobayashi A, Yamazaki N, Sugiyama K Published Date March 2013 Volume 2013:7 Pages 461 - 465 DOI: http://dx.doi.org/10.2147/OPTH.S42117 Received: 27 December 2012 Accepted: 14 January 2013 Published: 05 March 2013 Noriaki Murata, Hideaki Yokogawa, Akira Kobayashi, Natsuko Yamazaki, Kazuhisa Sugiyama Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan Background: In this paper, we report our experience of the clinical features of single and repeated globe rupture after penetrating keratoplasty. Methods: We undertook a retrospective analysis of single and repeated globe ruptures following keratoplasty in eight eyes from seven consecutive patients referred to Kanazawa University Hospital over a 10-year period from January 2002 to March 2012. We analyzed their ophthalmic and demographic data, including age at time of globe rupture, incidence, time interval between keratoplasty and globe rupture, cause of rupture, complicated ocular damage, and visual outcome after surgical repair. Results: Five patients (71.4%) experienced a single globe rupture and two patients (28.6%) experienced repeated globe ruptures. Patient age at the time of globe rupture was 75.4 ± 6.8 (range 67–83) years. Four of the patients were men and three were women. During the 10-year study period, the incidence of globe rupture following penetrating keratoplasty was 2.8%. The time interval between penetrating keratoplasty and globe rupture was 101 ± 92 months (range 7 months to 23 years). The most common cause of globe rupture in older patients was a fall (n = 5, 79.8 ± 3.7 years, all older than 67 years). Final best-corrected visual acuity was .20/200 in three eyes (37.5%). In all except one eye, globe rupture involved the graft-host junction; in the remaining eye, the rupture occurred after disruption of the extracapsular cataract extraction wound by blunt trauma. Conclusion: Preventative measures should be taken to avoid single and repeated ocular trauma following penetrating keratoplasty.
Polyatomic molecules in condensed phase: bond order index and solvation energy studied by RISM-SCF theory
H.Sato,D.Yokogawa,S.Sakaki
Condensed Matter Physics , 2007,
Abstract: The reference interaction site model - self-consistent field (RISM-SCF) theory was applied to a series of polyatomic molecules in aqueous solution, including CH4, NH3, H2O and HF. The bond order index, which characterizes the chemical bond, and its change by the solvation were studied by comparison with a dielectric continuum model. The change in the electronic structure was also associated with the solvation freeenergy.We find that the bond order indexes are not sensitive to the solvation effect even if the charge assigned to the atom is considerably changed. The distortion in the electronic energy is in proportion to the change in the solvation energy, showing that the linear response regime is a good expression of the solvation process examined here, in spite of solving the non-linear RISM-SCF equation.
Bowman’s layer encystment in cases of persistent Acanthamoeba keratitis
Yokogawa H,Kobayashi A,Yamazaki N,Ishibashi Y
Clinical Ophthalmology , 2012,
Abstract: Hideaki Yokogawa,1 Akira Kobayashi,1 Natsuko Yamazaki,1 Yasuhisa Ishibashi,2 Yosaburo Oikawa,3 Masaharu Tokoro,4 Kazuhisa Sugiyama11Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, 2Department of Ophthalmology, East Washinomiya Hospital, Kuki, 3Department of Medical Zoology, Kanazawa Medical University, Kahoku, 4Department of Parasitology, Kanazawa University Graduate School of Medical Science, Kanazawa, JapanBackground: The purpose of this study was to report Acanthamoeba encystment in Bowman’s layer in Japanese cases of persistent Acanthamoeba keratitis (AK).Methods: Laser confocal microscopic images of the cornea were obtained in vivo from 18 consecutive eyes from 17 confirmed AK patients. Retrospectively, 14 cases treated over 4 months were categorized as a nonpersistent group and three cases that required prolonged therapy for more than 6 months were categorized as a persistent group. Clinical outcomes based on final best-corrected visual acuity were retrospectively analyzed, and selected confocal images were evaluated qualitatively for abnormal findings.Results: The final best-corrected visual acuity was significantly lower (P < 0.01) for patients in the persistent group compared with that in the nonpersistent group. At the initial visit, in vivo confocal microscopy demonstrated Acanthamoeba cysts exclusively in the epithelial layer in both the nonpersistent group (80%) and the persistent group (100%). At a subsequent follow-up visit, numerous Acanthamoeba cysts were observed in the epithelial cell layer and in Bowman’s layer in all patients with persistent AK, but Acanthamoeba cysts were undetectable in all cases with nonpersistent AK tested.Conclusion: Invasion of cysts into Bowman’s layer was characteristically observed in patients with persistence of AK. This finding suggests that invasion of Acanthamoeba cysts into Bowman’s layer may be a useful predictor for a persistent clinical course.Keywords: Acanthamoeba keratitis, Bowman’s layer, encystment
Clinical features of single and repeated globe rupture after penetrating keratoplasty
Murata N,Yokogawa H,Kobayashi A,Yamazaki N
Clinical Ophthalmology , 2013,
Abstract: Noriaki Murata, Hideaki Yokogawa, Akira Kobayashi, Natsuko Yamazaki, Kazuhisa SugiyamaDepartment of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, JapanBackground: In this paper, we report our experience of the clinical features of single and repeated globe rupture after penetrating keratoplasty.Methods: We undertook a retrospective analysis of single and repeated globe ruptures following keratoplasty in eight eyes from seven consecutive patients referred to Kanazawa University Hospital over a 10-year period from January 2002 to March 2012. We analyzed their ophthalmic and demographic data, including age at time of globe rupture, incidence, time interval between keratoplasty and globe rupture, cause of rupture, complicated ocular damage, and visual outcome after surgical repair.Results: Five patients (71.4%) experienced a single globe rupture and two patients (28.6%) experienced repeated globe ruptures. Patient age at the time of globe rupture was 75.4 ± 6.8 (range 67–83) years. Four of the patients were men and three were women. During the 10-year study period, the incidence of globe rupture following penetrating keratoplasty was 2.8%. The time interval between penetrating keratoplasty and globe rupture was 101 ± 92 months (range 7 months to 23 years). The most common cause of globe rupture in older patients was a fall (n = 5, 79.8 ± 3.7 years, all older than 67 years). Final best-corrected visual acuity was .20/200 in three eyes (37.5%). In all except one eye, globe rupture involved the graft-host junction; in the remaining eye, the rupture occurred after disruption of the extracapsular cataract extraction wound by blunt trauma.Conclusion: Preventative measures should be taken to avoid single and repeated ocular trauma following penetrating keratoplasty.Keywords: repeated globe ruptures, penetrating keratoplasty, postoperative complications, ocular trauma
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