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Search Results: 1 - 10 of 78300 matches for " Yingxin Chen "
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Use the Substance-over-Form Convention to Regulate the Related Transaction
Yingxin Chen
International Journal of Business and Management , 2009, DOI: 10.5539/ijbm.v4n3p156
Abstract: Along with the coming of knowledge economic times, many enterprises form large groups by means of capital operations, including merger and purchase, reengineering, and stockholding. As a result, the relationships between enterprises tend to be more complex. Related parties and amounts of related transactions appear. For transactions or items that have inconsistent substances and forms, we must follow the substance-over-form convention in accounting. By this way, we can guarantee the quality of accounting information, regulate the accounting, and promote the development of market economy.
Research on the Role of Lawyers in Criminal Proceeding under the Provisions of the Vietnamese Criminal Procedure Code 2015  [PDF]
Cao Thi Tu Anh, Yingxin Chen
Open Journal of Social Sciences (JSS) , 2016, DOI: 10.4236/jss.2016.410006
Abstract: In Vietnam, the role of lawyers in criminal proceeding in general and adversarial in particular, plays an important role in contributes justice, legal rights/benefits protection for the accused or defendants, and assists to solve subjective cases lawfully. Vietnamese Criminal Procedure Code (VCPC) 2015 is established with numerous update regulations, in which they clearly stated and confirmed the upgrade of lawyers’ role in criminal proceeding, especially for adversarial one. This article is launched for discussion on lawyers’ role, especially in adversarial proceeding as per regulations of VCPC 2015, such as Right to enter Criminal proceeding, Equality with Other parties at court, Function of Plea submission for the accused or defendants. Moreover, the author also stated in this article some requirements for ensuring the upgrade of lawyer’s role in criminal proceeding at court.
New Insights into the Discovery of Novel Drugs to Treat Human Pulmonary Adenocarcinoma  [PDF]
Yu Wang, Haishan Zhang, Yingxin Chen, Lining Wang
Journal of Cancer Therapy (JCT) , 2019, DOI: 10.4236/jct.2019.102014
Abstract: Lung cancer is one of the most prevalent cancers in the world. A cisplatin-based chemotherapy regimen is commonly used to major patients who have adenocarcinoma. Because of the limited remission rate, many patients need receive second-line treatment after receiving first-line chemotherapy. Drug screenings carried out currently are mainly from single phase. In consideration of systemic treatment, evaluation of a novel drug candidate from the point of view of first-line and second-line treatment is supposed to be important in the process of drug screening. In this review, we propose a flow of searching for new drugs, which is tailored to accommodate to first-line and second-line treatment in clinic.
An ultrasound elastography method for examining the anterior cruciate ligament  [PDF]
Amy L. Cochran, Yingxin Gao
Natural Science (NS) , 2013, DOI: 10.4236/ns.2013.58A2004

We introduce an ultrasound elastography method for examining the ACL. It consisted of imaging the distal ACL while applying a drawer test and analyzing the resulting displacement and strain maps, where a map refers to how a variable is distributed spatially throughout an image. Our method was applied to healthy knees of cadaveric sheep to determine whether 1) our method can consistently generate displacements and strain maps in healthy ACLs; 2) displacement and strain maps are repeatable; and 3) healthy ACLs experience similar maps. We found that our method could consistently provide displacements and strain maps of the distal ACL region. Moreover, these ACLs experienced displacement and strain maps that were positively-correlated between trials, knees, and specimens. This correlation was statistically significant between pairs of trials and between left and right knees (p < 0.05). These results suggest that the maps are indeed repeatable and similar for healthy ACLs.

Optimization of an in vitro method to measure the bioaccessibility of polybrominated diphenyl ethers in dust using response surface methodology
Yingxin Yu,Yuping Pang,Xinyu Zhang,Chen Li,Zhiqiang Yu,Jiamo Fu,
Yingxin Yu
,Yuping Pang,Xinyu Zhang,Chen Li,Zhiqiang Yu,Jiamo Fu

环境科学学报(英文版) , 2011,
Abstract: To more reasonably evaluate human intake of PBDEs via dust ingestion, bioaccessibility should be taken into account. Previously, we developed an in vitro method to determine the bioaccessibility of PBDEs in food. Here, this method was adapted to determine the bioaccessibility of PBDEs in dust and the digestion conditions that influenced the bioaccessibility of PBDEs were optimized. The digestion conditions included the incubation time of dust in the intestinal digestion solution (T), the bile concentration in the intestinal digestion solution (Cbile), and the ratio of the volume of the intestinal digestion solution to dust (R). The influence of the concentrations of individual PBDE congeners (CPBDE) on the bioaccessibility of PBDEs was also investigated. Central composite design was used to build an experimental model and set experimental parameters, and response surface methodology was used to analyze the obtained data. The results showed that the bioaccessibility of PBDEs increased with the increases of Cbile and R, and was independent of T and CPBDE. Under the digestion conditions with Cbile and R being at 4.0-7.0 g/L and 150-250, respectively, the bioaccessibility of PBDEs in the method-dust varied from 39.2% to 72.8%, which were comparable with the bioaccessibility or bioavailability of PBDEs in dust/soil in the literature. Thus, the in vitro method to measure the bioaccessibility of PBDEs in dust was established and validated. Finally, the bioaccessibility of PBDEs in four natural dust samples, which ranged from 36.1% to 43.3%, were determined using the adapted method.
The Advantage of PET and CT Integration in Examination of Lung Tumors
Guangming Lu,Zhongqiu Wang,Hong Zhu,Linfeng Chang,Yingxin Chen,Jiang Wu,Yane Zhao
International Journal of Biomedical Imaging , 2007, DOI: 10.1155/2007/17131
Abstract: Purpose. To evaluate the diagnosis value of integrated positron emission tomography and computed tomography (PET/CT) with lung masses, this study emphasized the correlation between tumor size and maximum standardized uptake value (SUVmax) in selected regions of interest (ROI) of lung masses. Material and Methods. A retrospective analysis was performed on 85 patients with solid pulmonary lesions, all verified by pathology. The morphology, edge (speculated margins and lobule), size, density of pulmonary masses, and on-chest CT images were reviewed. The SUVmax in ROI of pulmonary masses was calculated. Results. Among the 85 patients with lung masses, 59 patients presented with pulmonary malignant neoplasm and 26 patients with benign lesions. The sensitivity, specificity, and accuracy were 89.8%, 61.5%, 81.2%, respectively, for PET measurement only, 88.1%, 65.4%, 81.2% for CT only, and 96.6%, 80.8%, 91.8% for PET/CT. The size of pulmonary malignant neoplasm in the 59 patients was apparently correlated with the ROI's SUVmax (r=0.617, P<.001). However, the size of pulmonary benign mass in the 26 patients was not correlated with the SUVmax. Conclusion. PET/CT is of greater value in characterization of lung masses than PET and CT performed separately. The examination of lung tumor can be further specified by the correlation between the size of pulmonary malignant neoplasm and the ROI's SUVmax.
NAD+-Carrying Mesoporous Silica Nanoparticles Can Prevent Oxidative Stress-Induced Energy Failures of Both Rodent Astrocytes and PC12 Cells
Heyu Chen, Yao Wang, Jixi Zhang, Yingxin Ma, Caixia Wang, Ying Zhou, Hongchen Gu, Weihai Ying
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0074100
Abstract: Aim To test the hypothesis that NAD+-carrying mesoporous silica nanoparticles (M-MSNs@NAD+) can effectively deliver NAD+ into cells to produce cytoprotective effects. Methods & Materials NAD+ was incorporated into M-MSNs. Primary rat astrocyte cultures and PC12 cells were treated with H2O2, followed by post-treatment with M-MSNs@NAD+. After various durations of the post-treatment, intracellular NAD+ levels, intracellular ATP levels and lactate dehydrogenase (LDH) release were determined. Results & Discussion M-MSNs can be effectively loaded with NAD+. The M-MSNs@NAD+ can significantly attenuate H2O2-induced NAD+ and ATP decreases in both astrocyte cultures and PC12 cells. M-MSNs@NAD+ can also partially prevent the H2O2-induced LDH release from both astrocyte cultures and PC12 cells. In contrast, the NAD+ that is spontaneously released from the M-MSNs@NAD+ is insufficient to prevent the H2O2-induced damage. Conclusions Our study has suggested the first approach that can effectively deliver NAD+ into cells, which provides an important basis both for elucidating the roles of intracellular NAD+ in biological functions and for therapeutic applications of NAD+. Our study has also provided the first direct evidence demonstrating a key role of NAD+ depletion in oxidative stress-induced ATP decreases.
Application of a Sign Language Synthesis System in Digital Library Services  [PDF]
Jing WAN, Bin WU, Yingxin QIAO
Intelligent Information Management (IIM) , 2009, DOI: 10.4236/iim.2009.11008
Abstract: Information Accessibility for disabled people is one of the most important design criteria for the China National Digital Library (CNDL) development. Sign language synthesis systems are effective to provide information services for people with hearing and speech impairments. This paper presents a framework of a sign language synthesis system application in CNDL, as well as discusses the relevant technologies applied in the system. CNDL has been a real practice area for the sign language synthesis research.
Comprehensive Benefit Analysis of Direct Expansion Ground Source Heat Pump System  [PDF]
Yuefen Gao, Yingxin Peng, Juanjuan Liu
Energy and Power Engineering (EPE) , 2013, DOI: 10.4236/epe.2013.52A009

Direct Expansion Ground Source Heat Pump (DXGSHP) system directly extracts heat or cold energy from ground by consuming electricity to provide for space conditioning. Compared with the currently widely-used secondary loop Ground Couple Heat Pump (GCHP) system, it has higher energy efficiency, lower operating costs, and less environmental impact. A case study is carried out in this paper. The subject is a residential building located in Beijing, China. It is assumed that the building adopts the DXGSHP system and the GCHP system respectively. Annual loads and energy consumption are simulated and computed. Then the initial cost, operating cost and CO2 emission are calculated. The economic benefit is analyzed with the Payback Time method and the Dynamic Annual Cost Value method. The environmental benefit is discussed mainly by comparing the CO2 emission savings. The results show that the DXGSHP system has higher initial costs, but lower operating costs, and less greenhouse gas emissions. The DXGSHP system has better comprehensive benefits than the GCHP system.

β-Adrenergic Stimulation Increases Cav3.1 Activity in Cardiac Myocytes through Protein Kinase A
Yingxin Li, Fang Wang, Xiaoying Zhang, Zhao Qi, Mingxin Tang, Christopher Szeto, Ying Li, Hongyu Zhang, Xiongwen Chen
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0039965
Abstract: The T-type Ca2+ channel (TTCC) plays important roles in cellular excitability and Ca2+ regulation. In the heart, TTCC is found in the sinoatrial nodal (SAN) and conduction cells. Cav3.1 encodes one of the three types of TTCCs. To date, there is no report regarding the regulation of Cav3.1 by β-adrenergic agonists, which is the topic of this study. Ventricular myocytes (VMs) from Cav3.1 double transgenic (TG) mice and SAN cells from wild type, Cav3.1 knockout, or Cav3.2 knockout mice were used to study β-adrenergic regulation of overexpressed or native Cav3.1-mediated T-type Ca2+ current (ICa-T(3.1)). ICa-T(3.1) was not found in control VMs but was robust in all examined TG-VMs. A β-adrenergic agonist (isoproterenol, ISO) and a cyclic AMP analog (dibutyryl-cAMP) significantly increased ICa-T(3.1) as well as ICa-L in TG-VMs at both physiological and room temperatures. The ISO effect on ICa-L and ICa-T in TG myocytes was blocked by H89, a PKA inhibitor. ICa-T was detected in control wildtype SAN cells but not in Cav3.1 knockout SAN cells, indicating the identity of ICa-T in normal SAN cells is mediated by Cav3.1. Real-time PCR confirmed the presence of Cav3.1 mRNA but not mRNAs of Cav3.2 and Cav3.3 in the SAN. ICa-T in SAN cells from wild type or Cav3.2 knockout mice was significantly increased by ISO, suggesting native Cav3.1 channels can be upregulated by the β-adrenergic (β-AR) system. In conclusion, β-adrenergic stimulation increases ICa-T(3.1) in cardiomyocytes, which is mediated by the cAMP/PKA pathway. The upregulation of ICa-T(3.1) by the β-adrenergic system could play important roles in cellular functions involving Cav3.1.
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