A Schiff base, (E)-ethyl-4-(2-oxoacenaphthylen-1(2H)-ylideneamino)benzoate, (E4AB) had been synthesized in good yield
by the acid-catalyzed condensation reaction of acenaphthenequinone and
ethyl-4-aminobenzoate in methanolic solution. The synthesized compound was
elucidated by elemental analysis (CHN), FTIR, 1H-NMR, 13C-NMR
and single crystal X-ray diffraction. E4AB crystallized in the monoclinic
crystal system with space group P21/c, Z = 4, V = 1569.3(2) ?3 and unit
cell parameters a = 9.1589(8) , b = 21.2003(17)?, c =8.4502(7) ?, β= 106.972(2)°.
The crystal structure of the compound is stabilized by intermolecular C-H···O hydrogen bonds and weak intermolecular π···π interactions. The title compound had been tested for
the antimicrobial activity against Bacillus
subtilis (B. subtilis), Enterobacter and Fusarium oxysporum f. sp. Cubense (Foc) by disc-diffusion method.
E4AB is relatively active against Foc which is a pathogen that cause Wilt disease (also well known as Panama disease)
in banana plantation.
A benzophenone substituted semicarbazone, 2-((3-aminophenyl)(phenyl)methylene)hydrazinecarboxamide
(APHC) had been synthesized in good yield by the condensation of
3-aminobenzophenone and semicarbazide hydrochloride. The title compound was
elucidated by elemental analysis (CHN), FTIR, 1H and 13C-NMR, 1H-1H COSY, TGA and single crystal X-ray diffraction. The
compound crystallized in the orthorhombic crystal system with space group of Pccn, Z = 32, V = 10375.1 (2) ?3, and lattice constants a = 12.3855 (1) ?, b = 34.5746 (5) ?, c =
24.2283 (3) ? and γ = β = α = 90°. The molecular view
shows that APHC contains four molecules of each species in the asymmetric unit,
with similar geometries. However, there is no intramolecular hydrogen bond
found in the crystal structure of the synthesized compound. X-ray diffraction
also reveals that the molecule of the semicarbazone exists as a Z isomer with respect to the C=N.