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Search Results: 1 - 10 of 126 matches for " Yasuhito Fujisaka "
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Practical Use of Gemcitabine and Cisplatin Combination Therapy as First-Line Treatment for Japanese Patients with Advanced Biliary Tract Cancer  [PDF]
Hisato Kawakami, Isamu Okamoto, Wataru Okamoto, Masayuki Takeda, Shinya Ueda, Toshihiro Kudo, Shin-ichi Nishina, Yasuhito Fujisaka, Masaki Miyazaki, Junji Tsurutani, Takayasu Kurata, Kazuhiko Nakagawa
Journal of Cancer Therapy (JCT) , 2013, DOI: 10.4236/jct.2013.46121
Abstract:

Gemcitabine and cisplatin combination therapy (GC) is accepted as a standard treatment for advanced biliary tract cancer (BTC). However, little information is available regarding such treatment in the clinical practice setting in Japan. We retrospectively examined the clinical data of patients with unresectable or recurrent BTC who received GC as first-line treatment. The regimen consisted of cisplatin (25 mg/m2) and gemcitabine (1000 mg/m2) administered intravenously on days 1 and 8 of repeated 3-week cycles. Twenty patients were analyzed. A total of 148 cycles of GC was administered, with a median of 8 and a range of 1 to 18 cycles. Treatment delay and dose reduction were noted in 35 (24%) and 41 (28%) of the 148 cycles, respectively. The major adverse events of grade 3 or 4 included neutropenia (50%), leukopenia (45%), anemia (30%), and thrombocytopenia (15%). Nonhematologic toxicities included nausea (10%), appetite loss (10%), and fatigue (10%). Median progression-free and overall survival times were 6.9 and 12.3 months, respectively. Gallbladder cancer showed a significantly higher response rate than did other types of BTC (chi-squaretest, P = 0.002). GC was thus effective and well tolerated as first-line chemotherapy for Japanese patients with advanced BTC in the clinical practice setting.

Preparation of Iron Ferrocyanide-Supported Nanofiber Membrane for Purification of Cesium-Contaminated Water  [PDF]
Yasuhito Mukai, Ayana Mizuno
Journal of Water Resource and Protection (JWARP) , 2014, DOI: 10.4236/jwarp.2014.64030
Abstract:

The earthquake in northeastern Japan that occurred on March 11, 2011 brought about the nuclear accident, resulting in the detection of radioactive cesium in soil and water over a wide region around Fukusihma. In this study, with the aim of the establishment of an effective method for removing cesium from water contaminated with cesium, the functionalized membrane with large cesium adsorption capacity per unit mass was prepared by combining nanofibers having a large specific surface area with iron ferrocyanide having a high selectivity for cesium adsorption. The nanofiber membrane made of polyacrylonitrile (PAN) was used as a base material of the functionalized membrane. Nanofiber membranes were immersed in the dispersions of iron ferrocyanide with various concentrations and pH values. After taking it out, it was dried at various temperatures and then non-immobilized iron ferrocyanide was completely removed through cleaning. As a result of the evaluation of completed affinity membranes, the amount of iron ferrocyanide immobilized by the nanofiber membrane increased significantly with the increase in the iron ferrocyanide concentration but subsequently showed a tendency to decrease rapidly, resulting in a distinct maximum at the iron ferrocyanide concentration of 3 wt%. And, the supported amount of iron ferrocyanide to the nanofiber membrane increased as pH became lower. Moreover, it was found that as high temperature as possible without exceeding the glass transition temperature of PAN was optimal as a drying temperature of prepared affinity membrane.

Coarse-graining and Self-similarity of Price Fluctuations
Yoshi Fujiwara,Hirokazu Fujisaka
Quantitative Finance , 2001, DOI: 10.1016/S0378-4371(01)00135-2
Abstract: We propose a new approach for analyzing price fluctuations in their strongly correlated regime ranging from minutes to months. This is done by employing a self-similarity assumption for the magnitude of coarse-grained price fluctuation or volatility. The existence of a Cramer function, the characteristic function for self-similarity, is confirmed by analyzing real price data from a stock market. We also discuss the close interrelation among our approach, the scaling-of-moments method and the multifractal approach for price fluctuations.
Undecidability of the existence of dictator for strongly candidate stable voting procedures in an infinite society and Cantor's diagonal argument
Tanaka, Yasuhito;
Computational & Applied Mathematics , 2008,
Abstract: the strong candidate stability theorem by dutta et al. [ 4], one of the major theoremsof social choice theory, states that, with a finite number of voters, there exists a dictator for any voting procedure which satisfies strong candidate stability, strong unanimity and independence of irrelevant alternatives (iia). this paper investigates a decidability problem of voting procedures in a society with an infinite number of individuals (infinite society) using cantor's diagonal argument presented by yanofsky [ 19] which is based on lawvere [ 10]. we will show the following result. the problem whether a strongly candidate stable voting procedure has a dictator or has no dictator in an infinite society is undecidable. it is proved using the arguments similar to those used to prove an extended version of cantor's theorem that there cannot be an onto function from (the set of natural numbers) to its power set (). this undecidability means that for any strongly candidate stable voting procedure we can not decide whether or not it has a dictator in finite steps by some program. a dictator of a voting procedure is a voter such that if he strictly prefers a candidate (denoted by x) to another candidate (denoted by y), then the voting procedure does not choose y. strong candidate stability requires that there be no change in the outcome of an election if a candidate withdraws who would lose ifevery candidate stood for office.
Various Notions about Constructive Brouwer's Fixed Point Theorem
Yasuhito Tanaka
IAENG International Journal of Applied Mathematics , 2012,
Abstract:
Constructive Proof of Brouwer's Fixed Point Theorem for Sequentially Locally Non-constant and Uniformly Sequentially Continuous Functions
Yasuhito Tanaka
IAENG International Journal of Applied Mathematics , 2012,
Abstract:
Constructive Proof of the Fan-Glicksberg Fixed Point Theorem for Sequentially Locally Non-constant Multi-functions in a Locally Convex Space
Yasuhito Tanaka
IAENG International Journal of Computer Science , 2013,
Abstract:
Proof of Constructive Version of the Fan-Glicksberg Fixed Point Theorem Directly by Sperner's Lemma and Approximate Nash Equilibrium with Continuous Strategies: A Constructive Analysis
Yasuhito Tanaka
IAENG International Journal of Applied Mathematics , 2011,
Abstract:
Brouwer's Fixed Point Theorem with Isolated Fixed Points and His Fan Theorem
Yasuhito Tanaka
ISRN Computational Mathematics , 2012, DOI: 10.5402/2012/843256
Abstract:
Constructive Proof of the Existence of Nash Equilibrium in a Finite Strategic Game with Sequentially Locally Nonconstant Payoff Functions
Yasuhito Tanaka
ISRN Computational Mathematics , 2012, DOI: 10.5402/2012/459459
Abstract:
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