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Search Results: 1 - 10 of 28358 matches for " Yanan Zhu "
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Relabelling Algorithms for Large Dataset Mixture Models
Wanchuang Zhu,Yanan Fan
Statistics , 2014,
Abstract: Mixture models are flexible tools in density estimation and classification problems. Bayesian estimation of such models typically relies on sampling from the posterior distribution using Markov chain Monte Carlo. Label switching arises because the posterior is invariant to permutations of the component parameters. Methods for dealing with label switching have been studied fairly extensively in the literature, with the most popular approaches being those based on loss functions. However, many of these algorithms turn out to be too slow in practice, and can be infeasible as the size and dimension of the data grow. In this article, we review earlier solutions which can scale up well for large data sets, and compare their performances on simulated and real datasets. In addition, we propose a new, and computationally efficient algorithm based on a loss function interpretation, and show that it can scale up well in larger problems. We conclude with some discussions and recommendations of all the methods studied.
Study on the Performance Optimization of Knitted Fabric Anti-Roll by Tissue Structure  [PDF]
Guoqiang Chen, Yanan Zhu
Journal of Materials Science and Chemical Engineering (MSCE) , 2018, DOI: 10.4236/msce.2018.64001
Will use the same number of positive and negative coil longitudinal organization of fabric is ta edge sex used in the work of the organization to warp fabric edge sex, between restrained knitting principle, design a kind of weft basketwork weaving method, especially in weft knitting machine woven from has the edge of weft knitted fabric performance weaving method. In order to overcome the existing technology aims to make weft basketwork structure of a single organization, edge sex is bad, or can’t produce rich weft knitted fabric appearance of shortage, provide a resistance to edge weft knitted fabric weaving method.
Quantitative Analysis of ATP Sulfurylase and Selenocysteine Methyltransferase Gene Expression in Different Organs of Tea Plant (Camellia sinensis)  [PDF]
Shaoqiang Tao, Juan Li, Xungang Gu, Yanan Wang, Qiang Xia, Bing Qin, Lin Zhu
American Journal of Plant Sciences (AJPS) , 2012, DOI: 10.4236/ajps.2012.31004
Abstract: Tea plant (Camellia sinensis) has unique biological features for the study of cellular and molecular mechanisms, an evergreen broad-leaved woody plant which can accumulate selenium in soil abundant of Selenium. Expression of the genes related to Selenium (Se) metabolism is an adaptation to the soil environment for a long period. The purpose of the present study was to explore if there exist differences of expression about these genes in tea plant between growing in Selenium-abundant and normal soil. A quantitative real-time reverse transcription polymerase chain reaction (Q-RT-PCR) assay was done for quantification of ATP sulfurylase (APS) and selenocysteine methyltransferase (SMT) mRNA normalized to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene in tea plant. Young leaves, mature leaves and tender roots from tea plants growing in soil abundant of Selenium were respectively obtained from Shitai County, Anhui Province, and also the relevant materials of the selenium un-enriched tea plant planted at agricultural garden of Ahui Agriculture University were taken as control for real-time PCR analysis. The results showed that APS1, APS2 and SMT expression levels for either young or mature leaves in selenium-enriched tea plant were lower than that in ordinary (selenium un-enriched) tea plant. In contrast, the APS1, APS2 and SMT expression level of roots in selenium-enriched tea plant were all higher than that in ordinary tea plant. APS1 gene expression level of roots in selenium-enriched tea plant was about 1.6 times higher than that in the ordinary tea plant, APS2 gene expression level was about 4.8-fold higher than that in the ordinary tea plant, SMT gene expression level was about 3.3 times higher than that in the ordinary tea plant. Among various tissues of selenium-enriched tea plant, APS1 gene relative expression level of young leaves was similar to or slightly higher than mature leaves, and the one of roots was the lowest among them; APS2 gene relative expression level of young leaves was similar to or slightly higher than the roots, and the one of mature leaves was the lowest among them; SMT gene relative expression level of young leaves was similar to or slightly higher than mature leaves, and the one of roots was the highest among them. Our results suggest that there existed correlation between selenium and expression levels of these genes.
Hualing Zhu,Zhan Wang,Zhen Wei,Yanan Bai
Acta Crystallographica Section E , 2011, DOI: 10.1107/s1600536811030753
Abstract: In the title complex, [Cu(C12H12N3O)2], the CuII ion is tetracoordinated by two N atoms and two O atoms from two bis-chelating 4-(1-iminoethyl)-3-methyl-1-phenyl-1H-pyrazol-5-olate ligands in a square-planar geometry. The two N atoms and two O atoms around the CuII atom are trans to each other, as the CuII atom lies on an inversion centre. The six-membered ring composed of the Cu, an O, an N and three C atoms of the ligand and the pyrazole ring is nearly planar, the largest deviation being 0.037 (4) for an N atom. In the crystal, weak intermolecular C—H...N hydrogen-bonding interactions link the molecules into chains along the c axis.
Hualing Zhu,Jun Shi,Zhen Wei,Yanan Bai
Acta Crystallographica Section E , 2010, DOI: 10.1107/s1600536810020532
Abstract: In the title compound, C23H23N5O2, an intramolecular N—H...O hydrogen bond generates an S(6) ring, and the dihedral angle between the pyrazole rings is 48.42 (8)°. The dihedral angles between the pyrazole rings and their attached phenyl rings are 10.06 (8) and 47.53 (8)°.
Antitumor Effects of Conditional Replication Adenovirus in Combination with Cisplatin on Lung Cancer  [PDF]
Yanan Liu, Yinghui Huang
Engineering (ENG) , 2012, DOI: 10.4236/eng.2012.410B042

Object: To explore the therapeutic effects and therapeutic mechanisms of Conditional Replication Adenovirus(CRAd) in combination with cisplatin on lung cancer cells. Methods: Using MTS / PMS assay, in vitro cell inhibition assay was performed to detect the cell viability of two lung cancer cell lines, NCI-H292 and NCI-H661. PCR was employed to detect the Coxsackie receptor(CAR) expression of cancer cells. The in vivo anti-tumor effect of CRAd and cisplatin was evaluated using a subcutaneous mouse model. Results: The CRAd with cisplatin is superior to the use of cisplatin or CRAd viruse alone on the suppression of lung cancer cell growth. The mechanism of inhibition is associated with the increased CAR expression. Conclusion: The application of CRAd in combination with cisplatin could play a better therapeutic effect on lung cancer cell growth inhibition.

Conditional Replication Adenovirus Sensitizes A549 Cancer Cell to Cisplatin  [PDF]
Yanan Liu, Yinghui Huang
Engineering (ENG) , 2012, DOI: 10.4236/eng.2012.410B043

Objective: The aim of the study was to improve the therapeutic effect for lung cancer using a synergetic strategy of adenovirus-based gene therapy combined with chemotherapy. Methods: A conditional replication adenovirus(CRAd) was employed to treat the A549 lung cancer cells and cisplatin-resisted A549(A549-DDP) cells. In vitro MTS / PMS assay were used to evaluate the cell viability. PCR were used to detect expression of Coxsackie receptor (CAR) and Multidrug resistance(MDR) gene. The in vivo anti-tumor effect of CRAd and cisplatin was evaluated using a subcutaneous mouse model. Results: The CRAd sensitizes A549 cancer cells to cisplatin. The mechanism of enhanced cell growth inhibition is associated with the increased CAR and MDR expression. Conclusion: Our approach is better than the conventional gene therapy and chemotherapy strategy.

Precise measurement technique for the stable acoustic cavitation bubble
Wei Huang,Weizhong Chen,Yanan Liu,Xianxian Gao,Li’an Jiang,Junfeng Xu,Yifei Zhu
Chinese Science Bulletin , 2005, DOI: 10.1007/BF03183629
Abstract: Based on the periodic oscillation of the stable acoustic cavitation bubble, we present a precise measurement technique for the bubble evolution. This technique comprises the lighting engineering of pulsing laser beam whose phase can be digitally shifted, and the long distance microphotographics. We used a laser, an acousto-optic modulator, a pulse generator, and a long distance microscope. The evolution of a levitated bubble can be directly shown by a series of bubble’s images at different phases. Numerical simulation in the framework of the Rayleigh-Plesset bubble dynamics well supported the experimental result, and the ambient radius of the bubble, an important parameter related to the mass of the gas inside the bubble, was obtained at the same time.
Analysis of microbial diversity of nitrifying bacteria by Terminal Restriction Fragment Length Polymorphism

Weitie Lin,Yanan Zhu,

生物工程学报 , 2010,
Abstract: We analyzed the microbial diversity and quantity of nitrifying bacteria in the enrichment reactor by Terminal Restriction Fragment Length Polymorphism (T_RFLP), a cultured-independent molecular technique. The result indicated that nitrobacteria enriched the best, and the diversity index decreased 62.80% compared with the initial data. Nitrobacteria were predominant in the reactor. Meanwhile, we studied the microbial diversity before and after adding Nitrobacteria into shrimp ponds, and analyzed several major bacterial species that existed stably in the pond. According to the analysis by T_RFLP program, species including Brevibacillus brevis, Microbacterium lactium, Azoarcus indigens and Bordetella holmesii were the dominant bacteria in the ponds.
Characterization Analysis of Response of Alcohol Dehydrogenase Gene (ADH1) in Coix lacroyma>/em> jobi L. to Waterlogging Stress
Advance Journal of Food Science and Technology , 2012,
Abstract: The aim of this study was focused on response of Alcohol Dehydrogenase gene (ADH1) in Coix to waterlogging stress. Based on the conserved sequence of Alcphol Dehydrogenase (ADH1) gene in maize, rice, and wheat, primers were designed to isolate theADH1 product. The full-length sequence of cDNA was firstly cloned by using RACE technology. The acquired gene contains an open reading frame (ORF, DQ455071.2) of 1140 bp and encodes 379 amino acids residues with the molecular weight and theoretical isoelectric of 40.965 and 6.13 KD, respectively. The BlastN/P analysis revealed that the sequence was highly homologous with gramineous plants such as ADH1 in maize, rice, and wheat. Moreover, it could be found in the phylogenetic tree that the origin of ADH1- encoding protein was most close to gramineous plants. It was predicted that it had at least two standard transmembrane segments, and the three-dimensional structure had 54.38% consistency with the reference model of 2 fzwa. The characteristic belt of ADH1 target protein was obtained by prokaryotic expression. Semi-quantitative analysis suggested thatADH1 gene expression was induced by waterlogging, and the expression in the root tip reached the highest level after 4 h of waterlogging, while ADH enzyme activity was also increased after waterlogging and reached the highest level after 6 h. Significant difference occurred in the ADH enzyme activities at different treatment time (p<0.05). Results indicated that ADH1 was sensitive to waterlogging and took part in tolerant and adaptive process under anaerobic environment.
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