oalib

OALib Journal期刊

ISSN: 2333-9721

费用:99美元

投稿

时间不限

2019 ( 6 )

2018 ( 86 )

2017 ( 81 )

2016 ( 125 )

自定义范围…

匹配条件: “ Y. Améyapoh” ,找到相关结果约53897条。
列表显示的所有文章,均可免费获取
第1页/共53897条
每页显示
Antimicrobial Activities of Syzygium aromaticum (L.) Merr. and L.M. Perry (Myrtaceae) Fruit Extracts on Six Standard Microorganisms and Their Clinical Counterpart  [PDF]
Y.-G. Afanyibo, K. Anani, K. Esseh, Y. Sadji, K. Idoh, K. Koudouvo, A. Agbonon, Y. Améyapoh, K. Tozo, M. Gbeassor
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104951
Abstract:
Syzygium aromaticum is used in combination with other plants as an al-coholic infusion by traditional practitioners to treat infections. It has been selected for evaluation for its antimicrobial properties to justify its use in traditional pharmacopoeia. The fruits were used as plant material while the microbial germs consisted of six reference strains: Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 29213, Salmonella typhimurium ATCC 14028, Pseudomonas aeruginosa ATCC 27853, Shigella flexneri ATCC 12022, Candida albicans ATCC 35659 and their clinical counterparts. The extracts were obtained by aqueous decoction, hydroethanolic and ethanolic macerations. The phytochemical screening was performed by chemical staining tests. The antibiotic susceptibility test was performed using the well diffusion method and the MIC and MBC or MFC were determined using the 96-well microplate dilution method. The results showed that 66.67% of the strains tested were sensitive to the aqueous extract with inhibition diameters ranging from 15 to 21 mm and MIC and MCB or MFC between 0.0976 - 0.3906 mg/mL and 0.1953 - 07812 mg/mL respectively, thus determining bacteriostatic activity. 100% of the germs tested were sensitive to hydroethanolic and ethanolic extracts. The inhibition diameters range from 12 - 28 mm for hydroethanolic extract with MIC and MBC or MFC ranging from 0.0488 - 0.3906 mm and 0.0488 - 0.7812 mm respectively. The ethanolic extract gave inhibition diameters of 12 - 26 mm; MIC and MBC or MFC ranging from 0.0976 - 0.7812 mm. Hydroethanolic extract gave three (3) bactericidal/fungicidal activities compared to four (4) as for ethanolic extract. These results prove the use of S. aromaticum among traditional recipes for treating infections in the pharmacopoeia but further studies remain important to produce traditionally improved drugs.
Caractéristiques physico-chimiques d’une lagune c tière tropicale : lagune de Fresco (C te d’Ivoire)
Y Issola, AM Kouassi, B Dongui, J Biemi
Afrique Science: Revue Internationale des Sciences et Technologie , 2008,
Abstract: Les variations saisonnières des paramètres physico-chimiques et hydrologiques de la lagune de Fresco ont été mesurées durant deux cycles annuels sur cinq stations. Il en résulte que la température, le pH, l’oxygène dissous et les sels nutritifs sont homogènement répartie sur le plan d’eau lagunaire. La distribution de la salinité et des MES y est hétérogène et permet de délimitée deux zones : - une zone océanique qui se comporte comme une baie avec des eaux peu renouvelées et un faible hydrodynamisme. Elle représente plus des 2/3 de la superficie de la lagune de Fresco ; - une zone continentale où l’influence des apports des rivières c tières Bolo et Niouniourou est très marqué. Les conclusions de cette étude permettent de classer la lagune de Fresco dans le système lagunaire Ebrié. Mots-clés : Hydrologie, physico-chimie, sels nutritifs, variations saisonnières, lagune c tière, Fresco, système lagunaire Ebrié
Particle size reduction to the nanometer range: a promising approach to improve buccal absorption of poorly water-soluble drugs
Rao S, Song Y, Peddie F, Evans AM
International Journal of Nanomedicine , 2011, DOI: http://dx.doi.org/10.2147/IJN.S19151
Abstract: rticle size reduction to the nanometer range: a promising approach to improve buccal absorption of poorly water-soluble drugs Original Research (4963) Total Article Views Authors: Rao S, Song Y, Peddie F, Evans AM Published Date June 2011 Volume 2011:6 Pages 1245 - 1251 DOI: http://dx.doi.org/10.2147/IJN.S19151 Shasha Rao, Yunmei Song, Frank Peddie, Allan M Evans Sansom Institute for Health Research, Division of Health Sciences, University of South Australia, Adelaide, South Australia, Australia Abstract: Poorly water-soluble drugs, such as phenylephrine, offer challenging problems for buccal drug delivery. In order to overcome these problems, particle size reduction (to the nanometer range) and cyclodextrin complexation were investigated for permeability enhancement. The apparent solubility in water and the buccal permeation of the original phenylephrine coarse powder, a phenylephrine–cyclodextrin complex and phenylephrine nanosuspensions were -characterized. The particle size and particle surface properties of phenylephrine nanosuspensions were used to optimize the size reduction process. The optimized phenylephrine nanosuspension was then freeze dried and incorporated into a multi-layered buccal patch, consisting of a small tablet adhered to a mucoadhesive film, yielding a phenylephrine buccal product with good dosage accuracy and improved mucosal permeability. The design of the buccal patch allows for drug incorporation without the need to change the mucoadhesive component, and is potentially suited to a range of poorly water-soluble compounds.
Description de la diversité génétique chez Brassica oleracea à l'aide de marqueurs isoenzymatiques et moléculaires
Margalé E,Chèvre AM,Delourme R,Hervé Y
Genetics Selection Evolution , 1994, DOI: 10.1186/1297-9686-26-s1-s137
Abstract:
Particle size reduction to the nanometer range: a promising approach to improve buccal absorption of poorly water-soluble drugs
Rao S,Song Y,Peddie F,Evans AM
International Journal of Nanomedicine , 2011,
Abstract: Shasha Rao, Yunmei Song, Frank Peddie, Allan M EvansSansom Institute for Health Research, Division of Health Sciences, University of South Australia, Adelaide, South Australia, AustraliaAbstract: Poorly water-soluble drugs, such as phenylephrine, offer challenging problems for buccal drug delivery. In order to overcome these problems, particle size reduction (to the nanometer range) and cyclodextrin complexation were investigated for permeability enhancement. The apparent solubility in water and the buccal permeation of the original phenylephrine coarse powder, a phenylephrine–cyclodextrin complex and phenylephrine nanosuspensions were -characterized. The particle size and particle surface properties of phenylephrine nanosuspensions were used to optimize the size reduction process. The optimized phenylephrine nanosuspension was then freeze dried and incorporated into a multi-layered buccal patch, consisting of a small tablet adhered to a mucoadhesive film, yielding a phenylephrine buccal product with good dosage accuracy and improved mucosal permeability. The design of the buccal patch allows for drug incorporation without the need to change the mucoadhesive component, and is potentially suited to a range of poorly water-soluble compounds.Keywords: buccal drug delivery, nanosuspension, solubility, permeation enhancement, mucoadhesion
Influence of asperities on fluid and thermal flow in a fracture: a coupled Lattice Boltzmann study
Amélie Neuville,Eirik Grude Flekk?y,Renaud Toussaint
Physics , 2013, DOI: 10.1002/jgrb.50256
Abstract: The characteristics of the hydro-thermal flow which occurs when a cold fluid is injected into a hot fractured bedrock depend on the morphology of the fracture. We consider a sharp triangular asperity, invariant in one direction, perturbing an otherwise flat fracture. We investigate its influence on the macroscopic hydraulic transmissivity and heat transfer efficiency, at fixed low Reynolds number. In this study, numerical simulations are done with a coupled lattice Boltzmann method that solves both the complete Navier-Stokes and advection-diffusion equations in three dimensions. The results are compared with those obtained under lubrication approximations which rely on many hypotheses and neglect the three-dimensional (3D) effects. The lubrication results are obtained by analytically solving the Stokes equation and a two-dimensional (integrated over the thickness) advection-diffusion equation. We use a lattice Boltzmann method with a double distribution (for mass and energy transport) on hypercubic and cubic lattices. Beyond some critical slope for the boundaries, the velocity profile is observed to be far from a quadratic profile in the vicinity of the sharp asperity: the fluid within the triangular asperity is quasi-static. We find that taking account of both the 3D effects and the cooling of the rock, are important for the thermal exchange. Neglecting these effects with lubrication approximations results in overestimating the heat exchange efficiency. The evolution of the temperature over time, towards steady state, also shows complex behavior: some sites alternately reheat and cool down several times, making it difficult to forecast the extracted heat.
Treatment of a Prolonged Air Leak with Radiotherapy: A Case Report
Erdo an etinkaya,M. Akif zgül, ule Gül,Ertan am,Yakup Büyükpolat
Case Reports in Pulmonology , 2012, DOI: 10.1155/2012/158371
Abstract: Pneumothorax is defined as air in the pleural space. Depending on the severity of the pneumothorax, treatment consists of oxygen therapy, simple aspiration, tube thoracostomy, and pleurodesis. Prolonged air leakage is observed in 25% of the patients who have undergone surgical procedures, such as thoracotomy, pleurectomy, and video-assisted thoracoscopy. The patient presented here is the third reported case successfully treated with radiotherapy. Ventilation scintigraphy was used to localise the air leak, and localised radiotherapy was performed at the targeted location. After radiotherapy, the air leak ceased and at the 3-month followup, the pneumothorax had not recurred. Radiotherapy can be a treatment modality for patients with prolonged air leak, who are not candidates for surgery.
Effect of Turkish propolis extracts on proteome of prostate cancer cell line
Ya?am Barlak, Orhan De?er, Meltem ?olak, Senem Karatayl?, Abdurrahman Bozday?, Fulya Yücesan
Proteome Science , 2011, DOI: 10.1186/1477-5956-9-74
Abstract: The antioxidant potentials of dimethyl sulfoxide and water extracts of propolis were found in correlation with the amount of total phenolic compounds of them. Dimethyl sulfoxide and water extracts of propolis of 20 μg/mL reduced the cell viability to 24.5% and 17.7%, respectively. Statistically significant discriminatory peaks between control PC-3 cells and dimethyl sulfoxide extract of propolis-treated PC-3 cells were found to be the proteomic features at m/z 5143, 8703, 12661, 20184 and 32794, detected by CM10 ProteinChip, and the peak at m/z 3772, detected by Q10 ProteinChip. Between control PC-3 cells and water extract of propolis-treated PC-3 cells, statistically significant discriminatory peaks were found to be the proteomic features at m/z 15846, 16052 and 24658, detected by CM10 ProteinChip and the peaks at m/z 10348, 10899 and 11603, detected by Q10 ProteinChip.It was concluded that dimethyl sulfoxide and water extracts of Turkish propolis may have anti-proliferative activity through differentiating protein expression profile in PC-3 prostate cancer cell lines along with their antioxidant capacity.Propolis is a natural, resinous hive product that honeybees manufacture by mixing their own waxes and salivated secretions with resins collected from the resin from the cracks in the bark of trees and leaf buds [1-4]. The chemical composition of propolis depends on the vegetation, climate, season and environmental conditions of the area from where it was collected [1,5]. It is mainly composed of resin and vegetable balsam (50%), wax (30%), essential and aromatic oils (10%), pollen (5%), and other various substances including organic compounds and minerals (5%) [3,5,6]. Organic compounds that are identified in different propolis samples are fatty and phenolic acids and esters, substituted phenolic esters, flavonoids (flavones, flavanones, flavonols, dihydroflavonols, chalcones), terpenes, β-steroids, aromatic aldehydes and alcohols, sesquiterpenes, naphtalene and s
Comparison of inflammatory microRNA expression in healthy and periodontitis tissues
Young H Wa Lee,Hee S Am Na,So Y Eon Jeong,Sung H Ee Jeong
Biocell , 2011,
Abstract: MicroRNAs (miRNAs) are short RNA molecules that negatively regulate gene expression primarily by degrading target mRNA or inhibit the translation of protein product. Recently, many reports have shown the altered miRNA expression in various diseases. However, there are no reports on miRNA expression related to periodontitis. Thus, this study aimed to compare the miRNAs differentially expressed in healthy and chronic periodontitis tissues and to determine the miRNAs closely associated with chronic periodontitis. To find out the miRNAs differentially induced in healthy and chronic periodontitis tissues, miRNA microarray was carried out and the expression of miRNAs was confirmed by real-time PCR. According to miRNA microarray analyses, six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. The expression of twenty-two miRNAs was increased more than 4 fold. Among these miRNAs, eight miRNAs which are known to be closely related to inflammation were selected. Six of these miRNA genes, miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. In summary, this study indicate that six miRNAs up-regulated in periodontitis gingiva may play a key role in chronic periodontitis.
Wave energy resource assessment and review of the technologies
Wan Nik WB, Sulaiman OO, Rosliza R, Prawoto Y, Muzathik AM
International Journal of Energy and Environment , 2011,
Abstract: Increase in human population has increased the demand for more energy. Technical improvement in transport and electrical appliances gives a lot of facilities to our life nowadays. Still we need to generate or convert this energy. Energy generation based on conventional technologies is always accompanied by environmental pollution. It gives overheating and greenhouse effects that later result in biosphere degradation. Nowadays sea wave energy is being increasingly regarded in many countries as a major and promising resource. It is renewable and environmentally friendly. In this paper wave parameters related to wave energy is analyzed. Then the paper describes the development of many different types of wave-energy converters. Several topics are addressed; the characterization of the wave energy resource, range of devices and how such devices can be organized into classes.
第1页/共53897条
每页显示


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.