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Search Results: 1 - 10 of 50478 matches for " Y Tettey "
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Still births at Korle Bu Teaching Hospital: characteristics of parents, pregnancy and labour
EK Wiredu, Y Tettey
Ghana Medical Journal , 2004,
Abstract:
Hormone receptor expression in male breast cancers
AB Akosa, S Van Norden, Y Tettey
Ghana Medical Journal , 2005,
Abstract: Male breast cancers are rare but have been found in higher proportions in Black Africans. Prognostic factors for breast cancers include tumour size, grade and stage, and hormone receptor status. The hormone receptor status is an invaluable guide in the use of adjuvant endocrine therapy, but none of the reports available in the literature from Africa showed any receptor work. This study was conducted to determine the grade, lymph node status and hormone receptor status of male breast cancers in Ghana. Nine archival cases of male breast cancers from the Pathology Department of Korle Bu Teaching Hospital were selected and studied on the basis of the presence of enough material for immunocytochemistry. Haematoxylin and Eosin (H & E) stained slides were reviewed and graded by Bloom and Richardson's criteria. Lymph node status was also assessed and sections were stained for oestrogen and progesterone receptors. Seven of the nine tumours were invasive ductal carcinomas and six of these were grade II, and one was grade III. Four cases had axillary lymph nodes removed at surgery and three were positive for metastases. Six (66%) of the cases were positive for oestrogen receptors with an H score ranging from 20 to 300. Using the criteria of McCarty et al, positivity for oestrogen receptor was reduced to 44%, which is lower than for Caucasians. We believe that this may be explained by the fact that in Ghana male breast cancers are seen a decade earlier. Only two cases were positive for progesterone receptor with an H score of 10 and 75. The two cases positive for progesterone receptors were also positive for oestrogen receptors. It is concluded that hormone receptor study is important in deciding on endocrine and adjuvant chemotherapy in male breast cancers and should be done routinely to help surgeons plan postoperative management of these patients. We recommend further research in this area.
Childhood deaths from malignant Neoplasms in accra
R.K Gyasi, Y Tettey
Ghana Medical Journal , 2007,
Abstract: Background: Malignant neoplasms are set to become a leading cause of childhood death in sub- Saharan Africa as immunization programmes reduce deaths due to infectious diseases. Knowledge of the pattern of deaths from these neoplasms is therefore desirable. Objective: To describe the pattern of deaths from paediatric malignancies, compare this to morbidity figures and provide baseline data for planning child care services. Methods: A 10 year retrospective survey of autopsy cases of paediatric malignancies at the Korle-Bu Teaching Hospital Mortuary was carried out based on autopsy files form January 1, 1990 to December 31, 1999 Results: A total of 252 cases of childhood malignant tumours were retrieved, 139 males and 113 females with a male to female ratio of 1.2:1. The most common malignancy was lymphoma forming 54% of cases and almost all of Non-Hodgkin’s type. Non-Burkitts type (29%) was the commonest followed by Burkitts (24%) and Hodgkin’s disease only one percent. The lymphomas were followed by central nervous system (CNS) tumours (13%), nephroblastomas(10.3%) leukemias (6.7%) hepatic tumours (4%) and sarcomas (2.6%). Less common tumours were Neuroblastomas (2.4%) and retinoblastomas (2%). Conclusion: Overall the pattern of deaths from paediatric malignancies followed the pattern of relative incidence in morbidity figures from Ghana and the subregion except for a relatively higher proportion of deaths from CNS tumours and a lower proportion from sarcomas. The pattern of cancer deaths seen in this study is similar to that seen in advanced countries except that lymphomas replace leukemia as the commonest cause of death
Colorectal Carcinoma: An Update of Current Trends in Accra
JCB Dakubo, SB Naaeder, Y Tettey, RK Gyasi
West African Journal of Medicine , 2010,
Abstract: BACKGROUND: Clinical experience and earlier studies indicate that the number of colorectal cancer cases seen annually in the Accra metropolis is increasing. OBJECTIVE: This study was aimed at providing a current update on colorectal cancer in Accra, Ghana. METHODS: A prospective study of confirmed cases of colorectal cancer diagnosed from January 1997 – December 2007. RESULTS: Three hundred and fifty-nine colorectal cancer cases were studied. Males were 192(53.5%) and females 167(46.5%) with an annual incidence of 32.6 new cases. The crude incidence rates were 12.53, 9.87 and 11.18 per 100,000 population for males, females and overall respectively. Rectal bleeding 185(51.1%), abdominal mass 76(21.1%), intestinal obstruction 62(17.3%), intestinal perforation nine (2.5%) and iron deficiency anaemia nine (2.5%) cases were the main presentations. There were 168 (46.8%) rectal and 191(53.2%) colon tumours. Two hundred and thirty-one patients had laparotomy with 225 resections, and 128 patients for various reasons did not undergo surgery. The Astler Coller stages of the tumours at diagnosis were C2 84(36.7%), C1 53(22.1%), B2 49(21.4%), D 17(7.4%), B1 14(6.1%) and A 12(5.1%) cases. Adenocarcinoma was the commonest histological type 321(89.4%), with the majority either well-differentiated (62.5%) or moderately well-differentiated (25.6) carcinomas. Poorly differentiated carcinomas accounted for 28 cases (7.8%). Post-operative mortality was 6.1%. Long term survival could not be assessed as the majority of patients were lost to follow up. CONCLUSION: The incidence of colorectal cancer has increased over the last four decades in tandem with an aging population of Accra with adenocarcinoma as the predominant histological type.
Eosinophilic enteritis – A diagnostic dilemma
JNA Clegg-Lamptey, Y Tettey, EK Wiredu, EY Kwawukume
West African Journal of Medicine , 2002,
Abstract: Eosinophilic enteritis is a rare condition of unknown aetiology, although it is generally believed to be due to intestinal allergy. It may mimic peptic ulcer, subacute (or chronic) intestinal obstruction, gastroenteritis, irritable bowel syndrome, and inflammatory bowel disease. The diagnosis is often difficult to make and most cases are only diagnosed after laparotomy / laparoscopy and biopsy. It can be successfully treated with corticosteroids. We report a case of Eosinophilic enteritis in a 27 year old woman the symptoms of which appeared within six weeks of childbirth. With repeated episodes of abdominal pain, vomiting, occasional loose stools with weight loss, she was investigated and treated for many weeks in three hospitals without success. All investigations were inconclusive. Finally laparotomy revealed inflamed segments of small bowel, a biopsy of which showed Eosinophilic enteritis. The patient was subsequently treated successfully with Prednisolone.
Cervical human papillomavirus infection in accra, Ghana
AB Domfeh, EK Wiredu, AA Adjei, PFK Ayeh-Kumi, TK Adiku, Y Tettey, RK Gyasi, HB Armah
Ghana Medical Journal , 2008,
Abstract: Background: This study was aimed at estimating the human papillomavirus (HPV) prevalence and its determinants among a sample of Ghanaian women. Design: Cross-sectional observational study. Setting: Gynaecology outpatient clinic of the Korle-Bu Teaching Hospital, Accra, Ghana; the largest tertiary care gynaecology outpatient clinic in Ghana. Participants: Convenient sample of 75 consenting women visiting the clinic. Methods: Information was obtained through personal interviews using structured questionnaire, Pap smears obtained, and laboratory testing of cervical exfoliated cells was performed. HPV DNA was detected using a GP5+/6+ polymerase chain reaction assay. These data were analyzed using both univariate and bivariate techniques. Results: The mean age of participants was 33.3 years (standard deviation, 9.2) and the percentage of lifetime monogamy was 21.3%. The crude HPV DNA prevalence was 10.7%. Unlike most populations studied so far, HPV prevalence was high not only among young women, but also in middle and old age. Independent HPV determinants were being illiterate (prevalence odds ratio [POR], 13.9; 95% confidence interval [95%CI], 1.9-100) and reporting more than three lifetime sexual partners (POR, 4.6; 95% CI, 1.0-22.2). Conclusions: The study indicates a high crude prevalence of HPV in a largely polygamous Ghanaian population with a high crude prevalence in older age groups, which may be a distinctive feature of polygamous populations where HPV transmission continues into middle age and cervical cancer incidence is very high.
Exploring the Factors That Hinder the Growth and Survival of Small Businesses in Ghana (A Case Study of Small Businesses within Kumasi Metropolitan Area)  [PDF]
Anthony Kusi, Christian Narh Opata, Tettey-Wayo John Narh
American Journal of Industrial and Business Management (AJIBM) , 2015, DOI: 10.4236/ajibm.2015.511070
Abstract: Micro, Small and Medium Scale Enterprises (MSMEs) contribute immensely to job creation, income generation and poverty reduction in emerging economies like that of Ghana. These positive contributions notwithstanding, most MSMEs in these economies have been performing poorly. This study therefore seeks to identify and analyze the challenges faced by MSMEs and proposed by appropriate measures that will enhance and sustain the vibrancy of MSMEs in order for them to perform their expected roles in the economic development process of Ghana. To be able to delve into the challenges of MSMEs in Ghana, a conceptual and theoretical framework is designed to guide the preparation of data collection instruments to suit the study. This involves a combination of survey and case study methods of data collection and analysis. The present study reveals that MSMEs are dominated by youth and female operators usually with low level of education. A further revelation is that majority of MSMEs lack qualified personnel; have poor access to credit and are usually self-financed. Based on the above, the study recommends the establishment of a common board to oversee the activities of support institutions for MSMEs. The study again proposes for the creation of MSMEs fund at all district, municipal and metropolitan areas to support MSMEs activities. Furthermore, the study is proposed for Bank of Ghana to create MSMEs bank to provide funds specifically for MSMEs development. Finally, effective implementation of the recommendation can lead to growth of MSME’s sector in Kumasi metropolis and eventually results in creation of employment as well as poverty reduction.
Surgically correctable adrenal-dependent hypertension: a report of five cases
F Ofei, R Darko, J Appiah-kusi, H Aduful, H Baddoo, Y Adugyamfi, Y Tettey, R.K Gyasi, L Aleksenko, E.D Yeboah, E.Q Archampong, A.A Yeboah, E Ogoe
Ghana Medical Journal , 2007,
Abstract: Although endocrine causes of secondary hypertension are relatively uncommon, medical practitioners must maintain a high index of suspicion for them in certain categories of patients. Such patients include young individuals, those with difficult- to-treat hypertension and those presenting with symptoms, clinical signs and/or laboratory parameters well-known to be associated with Cushing’s syndrome, Conn’s syndrome or phaeochromocytoma. This paper reports on 5 patients identified over a 2-year period with various hormonally-active adrenal adenomas causing hypertension in an environment where, hitherto, the occurrence of these conditions was generally thought to be rare. Aspects of the patients’ histories, examination and laboratory findings that drew attention to the possibility of the diagnosis in each case are highlighted, as are the confirmatory investigations and management methods used by a multidisciplinary team of medical practitioners. The clinical outcome with appropriate treatment of adrenalrelated hypertension is good and can result in significant cost savings in the long term.
Fault Classification using Pseudomodal Energies and Neuro-fuzzy modelling
Tshilidzi Marwala,Thando Tettey,Snehashish Chakraverty
Computer Science , 2007,
Abstract: This paper presents a fault classification method which makes use of a Takagi-Sugeno neuro-fuzzy model and Pseudomodal energies calculated from the vibration signals of cylindrical shells. The calculation of Pseudomodal Energies, for the purposes of condition monitoring, has previously been found to be an accurate method of extracting features from vibration signals. This calculation is therefore used to extract features from vibration signals obtained from a diverse population of cylindrical shells. Some of the cylinders in the population have faults in different substructures. The pseudomodal energies calculated from the vibration signals are then used as inputs to a neuro-fuzzy model. A leave-one-out cross-validation process is used to test the performance of the model. It is found that the neuro-fuzzy model is able to classify faults with an accuracy of 91.62%, which is higher than the previously used multilayer perceptron.
An Integrated Human-Computer System for Controlling Interstate Disputes
Tshilidzi Marwala,Monica Lagazio,Thando Tettey
Statistics , 2007,
Abstract: In this paper we develop a scientific approach to control inter-country conflict. This system makes use of a neural network and a feedback control approach. It was found that by controlling the four controllable inputs: Democracy, Dependency, Allies and Capability simultaneously, all the predicted dispute outcomes could be avoided. Furthermore, it was observed that controlling a single input Dependency or Capability also avoids all the predicted conflicts. When the influence of each input variable on conflict is assessed, Dependency, Capability, and Democracy emerge as key variables that influence conflict.
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