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Search Results: 1 - 10 of 120089 matches for " Xinyan Wang "
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L’évaluation formative dans l’enseignement des langues étrangères en Chine
WANG Xinyan
Synergies Chine , 2012,
Abstract: Dans le récent programme d’enseignement du fran ais langue seconde publié en 2011, l’évaluation formative y fait figure un nouveau venu. Notre article vise à présenter les concepts qui sous-tendent l’évaluation formative afin de fournir des informations utiles pour sa mise en application en Chine.
Molecular Characterization, 3D Modeling of Grass Carp Interleukin-10 Receptor 1 (IL10R1)  [PDF]
He Wei, Shangnian Wang, Lei Qin, Hong Zhou, Xinyan Wang
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.510B045

Interleukin-10 (IL-10) is an important cytokine that plays a pivotal role in natural and adaptive immune systems. However, in lower vertebrates, especially in teleost the receptor of this cytokine is still largely unknown. This paper described the cloning and characterization of grass carp interleukin-10 receptor 1 (gcIL10R1) and the 3D structure of its extracellular domain was predicted. The gcIL10R1 cDNA included 180 bp5’ untranslated region (UTR), 870 bp3’ UTR and an open reading frame (ORF) of 1632 bp. The ORF was found to encode a 543 amino acid protein with a putative JAK1 binding site, one STAT3 binding site. The phylogenetic analysis clusters gcIL10R1 with other teleost IL10R1s but independently of the amphibian, avian and mammalian IL10R1s. The 3D structure of its extracellular domain was the first homology model of a fish IL10R1 that revealed a high similarity with its mammalian and avian counterparts.

Fault Ride-Through Study of Wind Turbines  [PDF]
Xinyan Zhang, Xuan Cao, Weiqing Wang, Chao Yun
Journal of Power and Energy Engineering (JPEE) , 2013, DOI: 10.4236/jpee.2013.15004
Abstract: The installation of wind energy has increased rapidly around the world. The grid codes about the wind energy require wind turbine (WT) has the ability of fault (or low voltage) ride-through (FRT). To study the FRT operation of the wind farms, three methods were discussed. First, the rotor short current of doubly-fed induction generator (DFIG) was limited by introducing a rotor side protection circuit. Second, the voltage of DC bus was limited by a DC energy absorb circuit. Third, STATCOM was used to increase the low level voltages of the wind farm. Simulation under MATLAB was studied and the corresponding results were given and discussed. The methods proposed in this paper can limit the rotor short current and the DC voltage of the DFIG WT to some degree, but the voltage support to the power system during the fault largely depend on the installation place of STATCOM.
Molecular Cloning, Characterization and Expression Analysis of Macrohage-Colony Stimulating Factor 2 Gene from Grass Carp (Ctenopharyngodon idellus)  [PDF]
Linyong Du, Lei Qin, Shangnian Wang, Lu Yang, Kun Yang, Xinyan Wang, Hong Zhou
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.510B046

Macrophage colony-stimulating factor (CSF-1/M-CSF) is a key factor for the differentiation, growth and survival of monocytes/macrophages and osteoclasts. The functions of M-CSF have been well characterized in mammals. In this study, we have cloned and sequenced the cDNA of M-CSF2 in grass carp. The grass carp M-CSF2 cDNA was 1487 bp in length, containing an open reading frame of 855 bp that encodes 284 amino acids. The deduced protein of grass carp M-CSF2 possessed same domains similar to its mammalian counterparts. Multiple alignments and phylogenetic tree indicate that the grass carp M-CSF2 exhibits close evolutionary relationship with its counterparts in other teleosts. Lastly, the tissue distribution results also showed that the grass carp M-CSF2 transcript was dominantly expressed in head kidney, kidney and spleen in vivo.

Response of Subcutaneous Xenografts of Endometrial Cancer in Nude Mice to Inhibitors of Phosphatidylinositol 3-Kinase/Akt and Mitogen-Activated Protein Kinase (MAPK) Pathways: An Effective Therapeutic Strategy for Endometrial Cancer  [PDF]
Ruixia Guo, Xinyan Wang, Ruifang Zhang, Huirong Shi, Yuhuan Qiao, Wenjing Yun, Xin Ge, Yan Lin, Jia Lei
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.612118
Abstract: Objective: This study was designed to explore whether inhibition of the extracellular-regulated kinase (ERK) and phosphatidylinositol-3-kinase (PI3K) signaling pathways can inhibit the growth of xenografts of endometrial cancer cell lines with different estrogen receptors (ER) profiles in vivo and to provide preliminary laboratory basis for the probability of endometrial adenocarcinoma treatment with blockage of the two pathways, especially to endometrial cancer with low ER status. Methods: Human endometrial cancer Ishikawa bearing ER and HEC-1Awith low ER status cells were subcutaneously injected into BALB/c nude mice to establish endometrial cancer xenograft tumor models. The effects of PI3K/Akt inhibitor LY294002, MAPK/ERK1/2 inhibitor PD-98059 and their combinations on the growth of the xenograft tumors and apoptotic state of Ishikawa and HEC-1Acells were tested in vivo using the inhibitory rate, the terminal deoxynucleotidyl transferase-mediated nick-end labeling assay, H/E-stain. Western blot analysis was used to detect the alterations of activated ERK (P-ERK) and AKT (P-AKT) during this process. Results: LY294002, a PI3K/Akt pathway inhibitor, induced significant suppression in the growth of both Ishikawa and HEC-1Acell xenograft tumors, concomitant with increased apoptosis in xenografts as evidenced by TUNEL. A similar effect was also observed when the MAPK/ERK1/2 signaling pathway was inhibited by PD98059. Concurrent inhibition of the PI3K/Akt and MAPK/ERK1/2 pathways showed enhanced anti-tumor effects in vivo as indicated by increased apoptosis. At the same time, the levels of P-ERK and P-AKT in both xenograft tumors decreased, and their levels in combination group was the lowest. Conclusions: PD98059, LY294002 and their combinations showed remarkable inhibitory effects on xenograft tumors of endometrial carcinoma cell lines with different expression status of ER in vivo through blockage of PI3K/Akt and MAPK/ERK1/2 signaling pathways. This suggests that targeting these pathways may be an effective therapeutic strategy against endometrial carcinomas, especially for ER-negative cancers which show poor response to endocrinal therapy.
Giant magneto-impedance effects in nanocrystalline soft magnetic alloy ribbons
Wanjun Ku,Fuding Ge,Ge Yan,Xinyan Wang,Jing Zhu
Chinese Science Bulletin , 1997, DOI: 10.1007/BF02882632
Selecting Wheat Seeds of Moderate Phytate Using Colorimetric Method
Xinglin Li,Dandan Wang,Jie Gao,Xinyan Li
Journal of Agricultural Science , 2011, DOI: 10.5539/jas.v3n2p267
Abstract: A simple and effective method of determining the phytate content of a single wheat seed was considered necessary for selecting the materials of moderate phytate during early generations breeding. 23 wheat genotypes (16 winter wheat cultivars and 7 spring wheat cultivars) were firstly used as determining samples of phytate content (PC) and inorganic phosphorus content (IPC) of the whole meal, secondarily they were planted in two locations for two times (2004 and 2005). The all single plants were harvested by a plot from those sites, then 6 individual plants were randomly selected to save their seeds for each plot, and the seeds of other plants were grinded into whole meal to assay their PC and IPC. Subsequently, every seed from per individual plant was cut into two semi-grain seeds: the semi-grain seed without embryo (SGSWOE) and the semi-grain seed with embryo (SGSWE); the SGSWOE was carried out to assay colorimetric scoring values by inorganic phosphorus content (CSVIPC), while according to the CSVIPC index, the satisfied SGSWEs were saved to plant at next generation or the dissatisfied SGSWEs were eliminated. The results showed that there was significantly negative correlation between PC and IPC of the wheat meal from either the first samples or the materials harvested at those sites, and for the latter there was significantly negative correlation between PC and CSVIPC. There was no significant difference of CSVIPC among the SGSWEOs and SGSWE of the spikes and individual plants from the same plot or the same genotype at any sites. In conclusion the CSVIPC of the SGSWOEs can indirectly express PC level of the wheat meal: the higher the former was, the lower the latter was. So the CSVIPC of SGSWOE can be applied to assaying the level of corresponding SGSWE according to their index, and screening the individual plant of moderation phytate. Moreover, this method is characterized by high efficiency during breeding processing.
Microcomputed Tomography with Diffraction-Enhanced Imaging for Morphologic Characterization and Quantitative Evaluation of Microvessel of Hepatic Fibrosis in Rats
Jinghao Duan, Chunhong Hu, Shuqian Luo, Xinyan Zhao, Tailing Wang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0078176
Abstract: Backgroud Hepatic fibrosis can lead to deformation of vessel morphology and structure. In the present feasibility study, high-resolution computed tomography (CT) using diffraction-enhanced imaging (DEI) was used to represent three-dimensional (3D) vessel microstructures of hepatic fibrosis in rats and to differentiate different stages of hepatic fibrosis using qualitative descriptions and quantitative measurement of microvessels. Material and Methods Three typical specimens at different stages, i.e., mild, moderate and severe hepatic fibrosis, were imaged using DEI at 15 keV without contrast agents. The correspondence between DEI-CT images and histopathological findings was determined. The 3D visualizations from different stages of hepatic fibrosis were presented using DEI-CT. Additionally, Qualitative descriptions and quantitative evaluation of vessel features, such as vessel trend, vascular distortion deformation, thrombus formation and texture features on the inner wall of the vessel, were performed. Results DEI-CT produced high-resolution images of the vessel microstructures in hepatic fibrosis that corresponded to information on actual structures observed from the histological sections. Combined with the 3D visualization technique, DEI-CT enabled the acquisition of an accurate description of the 3D vessel morphology from different stages of hepatic fibrosis. Qualitative descriptions and quantitative assessment of microvessels demonstrated clear differences between the different stages of hepatic fibrosis. The thrombus inside the vessel of severe liver fibrosis was accurately displayed, and corresponding analysis can provide an exact measurement of vessel stenosis rate. Conclusions DEI-CT may allow morphologic descriptions and quantitative evaluation of vessel microstructures from different stages of hepatic fibrosis and can better characterize the various stages of fibrosis progression using high-resolution 3D vessel morphology.
Clinical Teleacupuncture between China and Austria Using Heart Rate Variability in Patients with Depression  [PDF]
Lu Wang, Guangyu Cheng, Zemin Sheng, Qianqian Niu, Weiping Cheng, Xiao Feng, Jan Valentini, Ingrid Gaischek, Xinyan Gao, Haixue Kuang, Gerhard Litscher
Chinese Medicine (CM) , 2011, DOI: 10.4236/cm.2011.22013
Abstract: In previous studies by the same research group it has been shown in post-stroke patients that the autonomic system can be affected by acupuncture. Within this study, teleacupuncture between China and Austria is used for quantifying the effects of heart rate variability (HRV) in Chinese patients suffering from depression. In 22 Chinese depression patients (17 f, 5 m; mean age ± SD 52.3 ± 10.6 years; range 31 - 70 years) electrocardiographic signals before, during and after acupuncture at the acupoint Jianshi (PC 5) were recorded in Harbin and analyzed in Graz using teleacupuncture via internet. HRV data were analyzed in the time and frequency domain and a protocol from Austria was sent to the team in China immediately after the treatment and recording session. Mean heart rate decreased significantly (p < 0.001) during and after acupuncture, whereas total HRV increased significantly during (p < 0.034) and after (p < 0.001) acupuncture, always immediately following manual needle stimulation. Furthermore, there is a marked decrease in balance between sympathetic and parasympathetic activity (low frequency/high frequency HRV ratio) during treatment. This study shows that HRV could be a useful parameter for quantifying clinical effects of acupuncture on the autonomic nervous system. Teleacupuncture between China and Austria over a distance of more than 8,500 km has been successfully used.
Cognitive Transfer and English writing
Xinyan Li
English Language Teaching , 2008, DOI: 10.5539/elt.v1n1p113
Abstract: The author examines the cognitive learning theory and cognitive transfer in English writing, tries to find out how it relates to English writing, and how it influences English writing.
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