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Search Results: 1 - 10 of 104257 matches for " Xinxin Zhang "
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Current perspectives on the efficacy and mechanisms of combination therapy for chronic hepatitis B virus
ZHANG Xinxin
Journal of Clinical Hepatology , 2013,
Abstract: The antiviral therapy is a main method to control chronic hepatitis B and prevent cirrhosis and hepatocarcinoma. However,the efficacy of current antiviral drugs are unsatisfactory. In order to optimize the antiviral strategy, it is worthy to investigate an important choice to combine antiviral drugs of different antiviral mechanism or different antiviral drug resistances. Although some relative studies and evidences have been taken, there are still many problems and arguments about combination therapy, which needs deep understanding of the pathogenesis and mechanism of poor antiviral response.
Empirical Evidence for a New Class of Personality Disorder: The Safety-Oriented Personality Style or Phobicentric Psychopathology (SOPS/PCP) and Impact on Personality Psychology  [PDF]
Patrick Bickersteth, Xinxin Zhang, Qi Guo
Psychology (PSYCH) , 2018, DOI: 10.4236/psych.2018.97098
Abstract: This study is aimed at establishing that the Safety-Oriented Personality Style (SOPS) or Phobicentric Psychopathology (PCP) is an actual mental disorder representing a disproportionate, self-focused pattern of reacting to ordinary fear-anxiety situations. SOPS/PCP is most similar to Neuroticism in the widely accepted Big 5 model. The presentation of personality within a dimensional structure is in contradistinction to that of the lately criticized category-based Diagnostic and Statistical Manual (DSM). Nonetheless contrasting both Big 5 and DSM, a neuro-biological theory provided the SOPS/PCP construct with etiological capability to empirically explain progress of the condition from normal to dysfunctional functioning, thus linking it with day-to-day emotional life. From a sample of 406 adults, who participated in confirming respectively that SOPS/PCP is present outside the clinical setting and is a real-world empirical condition, 100 individuals were randomly selected to examine the reliability and validity of the SOPS/PCP Individual Questionnaire (SOPSIQ). The results confirmed SOPS/PCP is an actual mental disorder, which is absent in some people and supported all the hypotheses in relation to the research objectives. In rivalry with three prominent formulations of personality, DSM, Big 5 and Interpersonal Relatedness & Self-Definition (IR), which is related to Contemporary Integrative Interpersonal Theory (CIIT), that of SOPS/PCP is presented as aspiring to be a more accurate elucidation of personality. Implications discussed also include suggesting DSM’s new categorical-dimensional platform is fatally flawed and questioning the investigative legitimacy of both the Big 5 and IR/CIIT. Among other ideas, it is suggested that SOPS/PCP might provide Big 5 with a presumptive etiological base; and that the behavior-to-theory approach of SOPS/PCP would be more research-friendly than the theory-to-behavior orientation prevalent in personality research. By describing personality functioning and its supporting theory as emotion-rooted this study recommends such a perspective makes it more practical to reliably define, track and eventually treat personality disorders.
The Optimal Investment Strategy Based on the DEA Model  [PDF]
Yulei Zhang, Shuai Zhang, Xinxin Zhang, Zhenping Li
Open Journal of Modelling and Simulation (OJMSi) , 2016, DOI: 10.4236/ojmsi.2016.42006
Abstract: The Goodgrant Foundation is a charitable organization that wants to improve education performance of undergraduates attending colleges and universities in the US. So the foundation plans to contribute a total of US 50 million for a suitable team of schools per year under the condition of avoiding repeated other large grant organizations’ investment. The DEA (Data Estimate Analysis) model is developed to determine an optimal investment strategy for the Goodgrant Foundation. In this paper, two questions were solved: how to choose a suitable team of schools and how to allocate the investment. Before the establishment of the model, the EXCEL software is used to preprocess data. Then the DEA model which includes two models in the paper is developed. For the first question, the CCR model is established to rank schools which used efficiency from DEAP 2.1. For the second question, the resource allocation model is established to allocate investment amount by weights of allocation from MATLAB software. Accordingly, the optimal investment strategy is received for the Goodgrant Foundation. Through the analysis above, 23 from 293 schools are selected to invest. Then the schools are ranked and the investment of US 50 million for 23 schools is allocated.
Seasonal Trends of Polycyclic Aromatic Hydrocarbons in Particulate Matter at an Urban Site in Beijing, China  [PDF]
Yanju Liu, Qingyang Liu, Xinxin Wang, Tingting Zhang
Journal of Geoscience and Environment Protection (GEP) , 2015, DOI: 10.4236/gep.2015.32002

This study was conducted to examine the impact of vehicular traffic emissions on the seasonal trends of polycyclic aromatic hydrocarbons (PAHs) concentration in particulate matter in Beijing. The PM10 and PM2.5 samples were collected at an urban site near the Third Ring Road in Beijing, China, from July 2009 to March 2010. Individual PAH concentrations at urban traffic site ranged from n.d. (below the detection limit, 0.2 ng/m3) to 558.49 ng/m3 of benzo(b)fluoranthene in PM10 samples and from n.d. to 177.93 ng/m3 also for benzo(b)fluoranthene in PM2.5 samples. Seasonal variations of PAHs compounds indicated that PAHs concentration in autumn and winter was higher than those in spring and summer. Results of PCA give four and five significant factors, which could explain 83.1% of the variation for PM2.5 and 85.3% of the variation for PM10, respectively.

Validation of the Questionnaire of Students’ Attitudes toward STEM-PBL: Can Students’ Attitude toward STEM-PBL Predict their Academic Achievement?  [PDF]
Mahnaz Shojaee, Ying Cui, Mehrdad Shahidi, Xinxin Zhang
Psychology (PSYCH) , 2019, DOI: 10.4236/psych.2019.102017
Abstract: The interdisciplinary curriculum of science, technology, engineering, math, and project-based learning (STEM-PBL) has currently received deep contemplation for its diverse benefits. This major attention has been focused on optimizing the curriculum by developing tools for assessing the diverse aspects of STEM in relation to teaching methods (e.g., PBL, teacher-centered learning, and game-based teaching), and students’ attitude. Following the principle of fallibility, the current research examined psychometric properties of the scale of students’ attitudes toward STEM-PBL. Also, the power of predictability of academic achievement by means of students’ attitude, and the mediating role of demographic factors were aimed to explore. The scale was completed by 337 students who were selected randomly. Using confirmatory factor analysis, Graded Response Modeling (GRM) based on Item Response Theory (IRT) provided technical informative details about each item of scale. Examining the items of scale displays reasonable psychometric properties including the validity of Student Attitude toward STEM-PBL Questionnaire. However, the analysis revealed that the removal of one of the items (item 22) may result in a better fit of the questionnaire. The results also showed that attitude toward STEM-PBL can predict students’ academic achievement using grade point average (GPA). Exploring the role of some mediating and demographic factors in this prediction revealed that self-learning had a high significant unique contribution in predicting GPA among respondents. The results displayed the significant association between GPA and students’ father education level. Also, students whose GPA and their fathers’ educational levels were high showed more positive attitude toward self-learning. Furthermore, the time of using technology and hands-on activity as a component of the students’ attitude toward STEM-PBL showed indirect relationship.
Fengxia Xie,Dan Zhang,Xinxin Zhang
Acta Crystallographica Section E , 2012, DOI: 10.1107/s1600536812020028
Abstract: In the asymmetric unit of the title polymeric compound, [Co(C8H4O4)(C5H5N)2]n, there are two crystallographically independent CoII atoms, each of which is six-coordinated in a distorted octahedral geometry by four O atoms from benzenedicarboxylate anions and two N atoms from pyridine ligands. The benzenedicarboxylate dianions bridge the CoII atoms into a tape running along the b axis. C—H...O hydrogen bonds are observed in the tape and between the tapes.
Determinants of the Wage Gap between Migrants and Local Urban Residents in China: 2002-2013  [PDF]
Xinxin Ma
Modern Economy (ME) , 2016, DOI: 10.4236/me.2016.77081
Abstract: This study explores the determinants of the wage gaps between rural-to-urban migrants and local urban residents in China from 2002 to 2013. Using the Chinese Household Income Project (CHIP) 2002 and 2013 survey data, the study provides an analysis based on the Oaxaca-Blinder decomposition model. The estimation results indicate that individual characteristics, regional location, and the distribution differences among industries and public and private sectors were the main factors causing the wage gaps. Furthermore, the main factors causing the wage gaps between 2002 and 2013 are human capital factors, industry sectors, and gender discrimination.
Business Start-Ups or Disguised Unemployment? Evidence on the Determinants of Self-Employment from Urban China  [PDF]
Xinxin Ma
Chinese Studies (ChnStd) , 2016, DOI: 10.4236/chnstd.2016.53009
Abstract: This study provides evidence on the determinants of self-employment for urban local registration residents in China. Using CHIP2007, the employment status is divided into four categories: self-employed employers, own-account workers, employees, and the unemployed. Several major con-clusions emerge. First, compared with the employee, holding other factors (e.g., human capital) constant, the wage premium associated with the self-employed employer is higher, while the wage premium associated with own-account workers is lower. Second, the influence of the wage premium on the self-employed employer is negatively significant, and the influence of the wage premium on the own-account workers is insignificant. These results reveal that compared with employees, being a self-employed or own-account worker is seemingly not a better choice for employment in urban China; being self-employed is similar to disguised unemployment. Third, considering the influence of all the factors: the wage level categories (wage levels in the public and private sectors), the entry period categories (the SOE reform period and the recent period), the age categories (aged 50 and over, and aged below 50), and the regional categories (the East, the Central, and the West regions), robust checks were conducted. In the own-account workers group, the business creation hypothesis is nearly rejected again; in fact, it is only supported for workers who entered the self-employment sector in the SOE reform period (entered early into the self-employment sector group), and workers aged over 50.
Impacts of Minimum Wage Policy on Wage Distributions in Urban China: Comparison between Public and Private Sectors  [PDF]
Xinxin Ma
Chinese Studies (ChnStd) , 2016, DOI: 10.4236/chnstd.2016.53006
Abstract: Using Chinese Household Income Project survey (CHIP) data, this study analyzes the impact of the Minimum Wage (MW) policy on average wage and wage distribution in urban China in the 1993-1995, the 1998-2002, and the 2007-2013 periods, and compared the MW effects between public and private sectors. Several major conclusions emerged from this study. First, comparatively, the overall impact of the MW on average wage in the 1993-1995 period is greater than the effect of the MW level on the average wage. Second, the MW effects on average wage exist in both the public and private sectors. However, holding the other factors consistent, the MW effect on average wage is greater for the private sector than for the public sector. Third, the overall effects of MW level on the low-wage group increased in the 2007-2013 period. Fourth, the effects of MW on wage distribution are greater for the private sector than for the public sector in the three periods. Holding the other factors consistent, the impact of MW on the low-wage group for the private sector increased greatly than for the public sector in the 2007-2013 period. Fifth, decomposition results indicated that the differences of distribution proportions, in regions with different MW levels between the public and private sectors helped reduce the wage gaps, as did the MW effects on wage, which were greater for the private sector than for the public sector in the 1993-1995 and 2007-2013 periods.
A Novel Identity-Based Multi-Signcryption Scheme
Jianhong Zhang,Yixian Yang,Xinxin Niu
International Journal of Distributed Sensor Networks , 2009, DOI: 10.1080/15501320802520613
Abstract: Message security and the sender's identity authentication for communication in the open channel is a basic and important technology of the internet. For keeping the message confidential and unforgeable, the sender can use a digital signature algorithm with his private key to sign the message, and then encrypts the signature on the message. Signcryption which was proposed by Zheng et. al in 1997 is a novel cryptographic primitive that simultaneously provides the authentication and encryption in a single logic step and at lower computational costs and communication overheads than the above sign-then-encrypt way. Since then, there are many signcryption schemes proposed. Only recently, a formal security proof model is formalized providing security proof for Zheng's signcryption in the random oracle model. In the ID-based cryptography, the complexity of the managing certificate is reduced.
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