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Search Results: 1 - 10 of 53588 matches for " Xin-Ying Ren "
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In silico identification of putative promoter motifs of White Spot Syndrome Virus
Hendrik Marks, Xin-Ying Ren, Hans Sandbrink, Mari?lle CW van Hulten, Just M Vlak
BMC Bioinformatics , 2006, DOI: 10.1186/1471-2105-7-309
Abstract: The collective information shows that the upstream region of early WSSV genes, containing a TATA box and an initiator, is similar to Drosophila RNA polymerase II core promoter sequences, suggesting utilization of the cellular transcription machinery for generating early transcripts. The alignment of the 5' ends of known well-established late genes, including all major structural protein genes, identified a degenerate motif (ATNAC) which could be involved in WSSV late transcription. For these genes, only one contained a functional TATA box. However, almost half of the WSSV late genes, as previously assigned by microarray analysis, did contain a TATA box in their upstream region.The data may suggest the presence of two separate classes of late WSSV genes, one exploiting the cellular RNA polymerase II system for mRNA synthesis and the other generating messengers by a new virus-induced transcription mechanism.White Spot Syndrome Virus (WSSV), type species of the virus family Nimaviridae (genus whispovirus), is a pathogen of major economic importance in cultured penaeid shrimp [1,2]. Histopathological studies on WSSV infected shrimp have shown that the virus mainly infects tissues of ectodermal and mesodermal origin, such as the stomach, gills, heart, gut, muscle tissue and hematopoietic tissue [3-5]. Infected cells within these tissues are characterized by the appearance of homogeneous hypertrophied nuclei and chromatin margination [1,5,6]. WSSV particles have been mainly detected in the nuclei of infected cells, indicating that transcription, replication and virion assembly probably occur in the nucleus [5-8]. It is not clear how the virions are released from the nucleus of an infected cell, but this most likely occurs by budding or by rupture of the nuclear envelope and/or the cell membrane.The circular ds DNA genome of three WSSV isolates, originating from Taiwan (WSSV-TW), China (WSSV-CN) and Thailand (WSSV-TH), have been completely sequenced [9-11]. The genome of W
Realization of a Video Convertion Module Based on Batch Programs
一种基于批处理的服务器端视频转换模块的实现

ZHAO Xin-Ying,
赵鑫莹

计算机系统应用 , 2011,
Abstract: This paper realizes a module which can convert almost all formats of current video files to files of flv format which can be played on the Web pages timingly, automaticly and batchingly. Firstly, it introduces current main video formats, along with Mencoder and Ffmpeg components. Secondly, it introduces the workflow design of this module. Finally, the paper introduces function realization of its submodules, and matters we should pay attention to in practical applications.
2,4-Dioxo-1-(prop-2-ynyl)-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
Yan He,Liang-Yan Cui,Xin-Ying Zhang
Acta Crystallographica Section E , 2011, DOI: 10.1107/s1600536811032272
Abstract: In the crystal structure of the title compound, C8H6N2O3, the molecules are linked by a pairs of intermolecular N—H...O hydrogen bonds, forming inversion dimers. The aldehyde group is in the same plane as the pyrimidine ring [with a maximum deviation of 0.083 (2) for the O atom), and the linear propargyl group [C—C—C = 178.99 (19)°] makes a dihedral angle of 74.36 (13)° with the ring.
Selective protection of nigral dopaminergic neurons by echinacoside in a rat model of Parkinson disease induced by rotenone
Xin-ying Feng,Wen-wei Li
Zhong Xi Yi Jie He Xue Bao , 2012,
Abstract: OBJECTIVE: To observe the protective effects of echinacoside on rotenone-induced damages in rats.METHODS: Healthy male Sprague-Dawley rats, weighing from 200 to 220 g, were randomly divided into five groups with 20 rats in each group: control group, rotenone group and echinacoside groups of low, medium and high doses (20, 40 and 80 mg/(kg·d)). Rats in the rotenone group were injected intraperitoneally for four weeks with rotenone (2.75 mg/(kg·d)), dissolved into dimethyl sulfoxide; rats in the control group were injected intraperitoneally with dimethyl sulfoxide daily, and rats in the echinacoside groups received daily intraperitoneal injection of rotenone along with echinacoside gastric perfusion for four weeks. Modified neurological severity score was used to evaluate neurobehavior of the animals; dopaminergic neurons in substantia nigra were observed by immunochemical method and dopamine concentration in striatum was determined by a fluorescence spectrophotometer. Biomarkers of liver and kidney damage were also measured.RESULTS: In the rotenone group, the rats suffered from severe neurological disability (P<0.01), and the number of dopaminergic neurons in substantia nigra and dopamine concentration in striatum were decreased (P<0.05) compared with the normal control group; levels of the biomarkers for evaluating liver and kidney damage were increased (P<0.05). In the echinacoside groups, the neurological disability and the loss of dopaminergic neurons in substantia nigra were suppressed and dopamine concentrations in striatum were increased (P<0.05), but the liver and kidney damage was not improved (P>0.05).CONCLUSION: Rotenone causes severe damages to dopaminergic neurons, liver and kidney in rats and echinacoside selectively reverses dopaminergic neuronal injury.
Neuroprotective Properties of Picroside II in a Rat Model of Focal Cerebral Ischemia
Qin Li,Zhen Li,Xin-ying Xu,Yun-liang Guo,Fang Du
International Journal of Molecular Sciences , 2010, DOI: 10.3390/ijms11114580
Abstract: The aim of this study was to explore the effect of picroside II on neuronal apoptosis and the expression of caspase-3 and poly ADP-ribose polymerase (PARP) following middle cerebral artery occlusion/reperfusion in male Wistar rats. Picroside II (10 mg/kg) was administered intravenously into the tail vein of the animals. The neurological function deficits were evaluated with the Bederson’s test and the cerebral infarction volume was visualized with tetrazolium chloride (TTC) staining. The apoptotic cells were counted by in situ terminal deoxynucleotidyl transferase-mediated biotinylated deoxyuridine triphosphate nick end labeling (TUNEL) assay. The immunohistochemistry stain and enzyme linked immunosorbent assay (ELISA) was used to determine the expressions of caspase-3 and PARP in brain tissue. The results indicated that rats in the control group showed neurological function deficit and cerebral infarction in ischemic hemisphere after two hours ischemia followed by 22 hours reperfusion. Caspase-3 and PARP expressions were also profound in the cortex, the striatum and the hippocampus, along with increased apoptotic cells in this group. Bederson's score, infarction volume, and expressions of caspase-3 and PARP, as well as apoptosis in the treatment group were, however, significantly decreased compared to those in the control group indicating that intravenous treatment with picroside II might be beneficial to inhibit neuronal apoptosis and, thus, to improve the neurological function of rats upon cerebral ischemia reperfusion injury.
Multivariate chaotic time series prediction based on extreme learning machine
基于极端学习机的多变量混沌时间序列预测

Wang Xin-Ying,Han Min,
王新迎
,韩敏

物理学报 , 2012,
Abstract: For multivariate chaotic time series prediction problem, a prediction based on input variable selection and extreme learning machine is proposed in this paper. The multivariate chaotic time series is reconstructed in phase space, and a mutual information based method is used to select the input variables, which have high statistics information with the output variables. The extreme learning machine is conducted to model the multivariate chaotic time series in the phase space by utilizing its approximation capability. In order to improve the prediction accuracy, a model selection algorithm is conducted for extreme learning machine to choose an expected minimum risk prediction model. Simulation results based on Lorenz, R ssler multivariate chaotic time series and R ssler hyperchaotic time series show the effectiveness of the proposed method.
Classical Exchange Algebra of the Nonlinear Sigma Model on a Supercoset Target with 2n Grading

KE San-Min,LI Xin-Ying,WANG Chun,YUE Rui-Hong,

中国物理快报 , 2011,
Abstract:
An Effective Online Sparse Learning Algorithm for Echo State Networks
一种有效的储备池在线稀疏学习算法

HAN Min,WANG Xin-Ying,
韩敏
,王新迎

自动化学报 , 2011,
Abstract: In order to overcome the lack of effective online learning method for echo state networks and to solve the ill-posed problem of reservoir, an effective online sparse learning algorithm is proposed for echo state networks in this paper. An L1 regularization constraint is added to the objective function of reservoir, and a truncated gradient algorithm is used to approximately solve the problem online. The proposed method can adjust the output weights of reservoir online, control the sparsity of the output weights, and ensure the generalization performance.Theoretical analysis and simulation results demonstrate the effectiveness of the algorithm.
Kinetics of catalytically activated aggregation-fragmentation process

Gao Yan,Wang Hai-Feng,Lin Zhen-Quan,Xue Xin-Ying,

中国物理 B , 2011,
Abstract:
Research of Software Component for Open Embedded Automotive Application
车用嵌入式开放系统的软构件研究

LUAN Xin-ying,SUN Xiao-min,
栾鑫颖
,孙晓民

计算机应用研究 , 2006,
Abstract: Software for embedded system is hard to maintain, update and customize. However, Component-based software engineering would bring a number of advantages to the embedded applications. The characteristics and mechanism of embedded software component are analyzed in detail. The embedded software component based on OSEK standard for automotive and its development tools are presented and discussed.
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