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Search Results: 1 - 10 of 12834 matches for " Xiaoyang Luo "
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Study on the Pension Rights of Families That Have Lost Their Only Child  [PDF]
Xiaoyang Zhang
Beijing Law Review (BLR) , 2015, DOI: 10.4236/blr.2015.61003
Abstract: According to incomplete statistics, the number of families that have lost their only child had reached more than one million in China currently, following an annual increase by 76,000. The problem of elder care of these families that have lost their only child has become a hot issue in China. Legislation and relevant policies about families that have lost their only child are not sufficient, which have caused the lack of basis on establishing a reasonable elder care system of those families. This paper is aiming to address the rights as a core and further supplement on the basis of the present situation of families that have lost their only child, therefore implement to build the pension right system of loss of only child families. Meanwhile, we also strive to put forward specific advices on establishing legislation and relevant policies.
The role of Endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) for qualitative diagnosis of mediastinal and hilar lymphadenopathy: a prospective analysis
Ting Ye, Hong Hu, Xiaoyang Luo, Haiquan Chen
BMC Cancer , 2011, DOI: 10.1186/1471-2407-11-100
Abstract: 101 patients with mediastinal and hilar lymphadenopathy or suspected lung cancer in our institution were included in this prospective study. EBUS-TBNA was performed in all cases. The final diagnosis was confirmed by cytology, surgical results, and/or clinical follow-up for at least 6 months. Sensitivity, specificity, accuracy, and positive and negative predictive values were calculated using standard formulas.In 101 patients, EBUS-TBNA was successfully performed to obtain samples from 225 lymph nodes, 7 lung masses, 1 mediastinal mass and 2 esophageal masses. 63 malignant tumors and 38 benign diseases were confirmed. Epidermal growth factor receptor mutation was detected in 10 biopsy samples, and epidermal growth factor receptor mutation was detected in 4 cases. With respect to the correct diagnosis of mediastinal and hilar lymphadenopathy, EBUS-TBNA had a sensitivity of 95.08%, specificity of 100%, positive predictive value of 100%, negative predictive value of 93.02%, and overall accuracy of 97.02%. The relationship of diagnostic accuracy and number of lymph node passes or size of lymph nodes was both insignificant (p = 0.27; p = 0.23). The procedure was uneventful without complications.EBUS-TBNA is an accurate and safe tool in diagnosis of mediastinal and hilar lymphadenopathy. It cannot completely replace mediastinoscopy, it may indeed reduce the number of mediastinoscopy procedures. In some cases, it can necessarily be the first-line procedure before mediastinoscopy.Patients with mediastinal lymphadenopathy or suspected lung cancer required accurate diagnosis to determine optimal treatment. For these patients, mediastinal nodal sampling is often necessary and has traditionally been performed by mediastinoscopy or anterior mediastinotomy. However, mediastinoscopy, with a sensitivity of 80% to 85% and a specificity of nearly 100%, which is considered the gold standard for diagnosis with tissue confirmation of mediastinal lymphadenophy and lung cancer with mediast
Molecular mechanism of effect of rotating constant magnetic field on organisms
Xiaoyun Zhang,Zhenguo Luo,Xiaoyang He,Qingguo Han,Weide Zhang
Science China Life Sciences , 2001, DOI: 10.1007/BF02882398
Abstract: The effect of RCMF-magnetic therapy apparatus on signal substances was studied. The radioimmunoassay (RIA) suggested that the magnetic field increased β-endorphin markedly in plasma. ELISA indicated that the magnetic field inhibited vomiting reaction induced by chemotherapy drug, with reversible decrease of serotonin (5-HT) level in brains, small intestine tissue and serum. Furthermore, the bioeffect of magnetic fields on 5-HT level presented a typical window effect and post-effect, and the inhibitory effect of magnetic field on the emesis was parallel to the decrease level of 5-HT. This result implied that the decrease of 5-HT might be the basis of rotating constant magnetic field (RCMF) inhibiting drug-induced emesis. The nitric acid reductase-spectrophotometry and nicotinamide adenine dinucleotide-diaphorase/arginine-vasopressin (AVP) cytochemistry technique showed that the magnetic field induced nitric oxide (NO) increase in hypothalamus and the high NO(A) level lasted for 3 hours. The results suggested that NO(A) increases after the treatment of the magnetic field in hypothalamus, which may result from strong expression of NO-ergic neuron in paraventricular hypothalamic nucleus (PVN), periventricular hypothalamic nucleus (PEN) and supraoptic nucleus (SON). The coexistence of NO and AVP may play an important role in the regulation of endocrine and neuroendocrine by the magnetic field. And our data also confirmed that the magnetic field increased the content of NO so strongly that high NO level lasted for 3 hours, also made neuropeptide Y (NPY) cell in medulla stained heavily.
Molecular Dynamics Simulations of DOPC Lipid Bilayers: The Effect of Lennard-Jones Parameters of Hydrocarbon Chains  [PDF]
Anping Liu, Xiaoyang Qi
Computational Molecular Bioscience (CMB) , 2012, DOI: 10.4236/cmb.2012.23007
Abstract: The current Chemistry at Harvard Molecular Mechanics (CHARMM) force field cannot accurately describe the properties of unsaturated phospholipid membranes. In this paper, a series of simulations was performed in which the Lennard- Jones (L-J) parameters of lipid acyl chains of dioleoylphosphatidylcholine (DOPC) were systematically adjusted. The results showed that adjustment of the L-J parameters in lipid acyl chains can significantly improve the current CHARMM force field. It was found that the L-J parameters have different influences on the order parameters of the top half and bottom half of the chain, separated by the cis double bond. The order parameters of the top half and the bottom half of the chain are related to the area/lipid and the length of the chain, respectively.
Power Balance of Multi-Harmonic Components in Nonlinear Network  [PDF]
Binghua Huang, Xiaoyang He
Journal of Modern Physics (JMP) , 2014, DOI: 10.4236/jmp.2014.514132
Abstract:

The main harmonic components in nonlinear differential equations can be solved by using the harmonic balance principle. The nonlinear coupling relation among various harmonics can be found by balance theorem of frequency domain. The superhet receiver circuits which are described by nonlinear differential equation of comprising even degree terms include three main harmonic components: the difference frequency and two signal frequencies. Based on the nonlinear coupling relation, taking superhet circuit as an example, this paper demonstrates that the every one of three main harmonics in networks must individually observe conservation of complex power. The power of difference frequency is from variable-frequency device. And total dissipative power of each harmonic is equal to zero. These conclusions can also be verified by the traditional harmonic analysis. The oscillation solutions which consist of the mixture of three main harmonics possess very long oscillation period, the spectral distribution are very tight, similar to evolution from doubling period leading to chaos. It can be illustrated that the chaos is sufficient or infinite extension of the oscillation period. In fact, the oscillation solutions plotted by numerical simulation all are certainly a periodic function of discrete spectrum. When phase portrait plotted hasn’t finished one cycle, it is shown as aperiodic chaos.

Discontinuous Legendre Wavelet Galerkin Method for One-Dimensional Advection-Diffusion Equation  [PDF]
Xiaoyang Zheng, Zhengyuan Wei
Applied Mathematics (AM) , 2015, DOI: 10.4236/am.2015.69141
Abstract: This paper presents discontinuous Legendre wavelet Galerkin (DLWG) approach for solving one-dimensional advection-diffusion equation (ADE). Variational formulation of this type equation and corresponding numerical fluxes are devised by utilizing the advantages of both the Legendre wavelet bases and discontinuous Galerkin (DG) method. The distinctive features of the proposed method are its simple applicability for a variety of boundary conditions and able to effectively approximate the solution of PDEs with less storage space and execution. The results of a numerical experiment are provided to verify the efficiency of the designed new technique.
Estimates of Approximation Error by Legendre Wavelet  [PDF]
Xiaoyang Zheng, Zhengyuan Wei
Applied Mathematics (AM) , 2016, DOI: 10.4236/am.2016.77063
Abstract: This paper first introduces Legendre wavelet bases and derives their rich properties. Then these properties are applied to estimation of approximation error upper bounded in spaces \"\"?and \"\"?by norms \"\"?and \"\"?, respectively. These estimate results are valuable to solve integral-differential equations by Legendre wavelet method.
Compressive Behavior of Steel Members Reinforced by Patch Plate with Welding and Bonding  [PDF]
Xiaoyang Liu, Mikihito Hirohata
Open Journal of Civil Engineering (OJCE) , 2018, DOI: 10.4236/ojce.2018.84026
Abstract: Repair and reinformcement of aged civil steel structures is one of the important issues for maintaining and using them for a long term. For repair and reinforcement of deteriorated civil steel structures due to fatigue and corrosion, patch plate reinforcement is widely applied. Bolting is generally used because of easy quality control and many construction achievements. However, bolting has downsides including holes made and weight increase. Welding is considered to overcome these demerits but in reality the application of welding is unsatisfactory due to the possibility of fatigue crack occurring from the welded part. In this study, a patch plate strengthening system of welded joint assisted with bonding has been proposed. The compressive behaviors of weld-bond jointed specimen were investigated by a series of experiments and FE analysis. It was confirmed that use of welding and bonding was effective to enhance compressive strength of specimen, due to better load-carrying capacity of patch plate compared with sole use of welding.
The Caenorhabditis elegans Gene mfap-1 Encodes a Nuclear Protein That Affects Alternative Splicing
Long Ma ,Xiaoyang Gao,Jintao Luo,Liange Huang,Yanling Teng,H. Robert Horvitz
PLOS Genetics , 2012, DOI: 10.1371/journal.pgen.1002827
Abstract: RNA splicing is a major regulatory mechanism for controlling eukaryotic gene expression. By generating various splice isoforms from a single pre–mRNA, alternative splicing plays a key role in promoting the evolving complexity of metazoans. Numerous splicing factors have been identified. However, the in vivo functions of many splicing factors remain to be understood. In vivo studies are essential for understanding the molecular mechanisms of RNA splicing and the biology of numerous RNA splicing-related diseases. We previously isolated a Caenorhabditis elegans mutant defective in an essential gene from a genetic screen for suppressors of the rubberband Unc phenotype of unc-93(e1500) animals. This mutant contains missense mutations in two adjacent codons of the C. elegans microfibrillar-associated protein 1 gene mfap-1. mfap-1(n4564 n5214) suppresses the Unc phenotypes of different rubberband Unc mutants in a pattern similar to that of mutations in the splicing factor genes uaf-1 (the C. elegans U2AF large subunit gene) and sfa-1 (the C. elegans SF1/BBP gene). We used the endogenous gene tos-1 as a reporter for splicing and detected increased intron 1 retention and exon 3 skipping of tos-1 transcripts in mfap-1(n4564 n5214) animals. Using a yeast two-hybrid screen, we isolated splicing factors as potential MFAP-1 interactors. Our studies indicate that C. elegans mfap-1 encodes a splicing factor that can affect alternative splicing.
Relationship between tumor size and disease stage in non-small cell lung cancer
Fu Yang, Haiquan Chen, Jiaqing Xiang, Yawei Zhang, Jianhua Zhou, Hong Hu, Jie Zhang, Xiaoyang Luo
BMC Cancer , 2010, DOI: 10.1186/1471-2407-10-474
Abstract: We conducted a retrospective analysis of 917 cases of NSCLC that were resected in the Cancer Hospital of Fudan University and Shanghai Sixth Hospital between January 2000 and February 2009. Tumor sizes were grouped into five categories: ≤20 mm, 21 to 30 mm, 31 to 50 mm, 51 to 70 mm and ≥71 mm.Age and tumor size affected stage distribution: patients 60 years or older had a higher percentage of N0M0 disease than patients younger than 60 years (61.67% vs. 44.85%, p < 0.01). The smaller the tumor, the more likely the disease was N0M0 status (p < 0.05). For tumors ≤20 mm in diameter, the proportion of cases with N0M0 status was 70.79%, compared to 58.88% for 21 to 30 mm, 48.03% for 31 to 50 mm, 47.55% for 51 to 70 mm, 33.33% for ≥71 mm. The mean (± SD) tumor size of cases with N0M0 status was 37.17 ± 21.34 mm, compared to 45.75 ± 23.19 mm for cases with other status.There is a statistically significant relationship between tumor size and distribution of disease stage of primary NSCLC tumors: the smaller the tumor, the more likely the disease is N0M0 status.Lung cancer is the leading cause of cancer-related death worldwide. A total of 497,908 new lung cancer cases and 428,938 deaths from lung cancer are estimated to have occurred in China in 2005 [1,2]. When diagnosis and treatment are initiated early, lung cancer can be cured. In the database of IASLC, the 5-year survival rate of patients with pathologic and clinical stage IA non-small cell lung cancer (NSCLC) is 73% and 50%, respectively [3]. In contrast, the 5-year survival is only 13% and 2% for patients with pathologic and clinical stage IV disease, respectively [3]. Unfortunately, 75%~80% patients with NSCLC are diagnosed with locally advanced or advanced disease [4], resulting in a dismal overall 5-year survival of 15.7% [5,6].This state implies that to improve survival, efforts should be made to detect NSCLC in earlier stages so that curative surgery can be performed. Lung cancer screening trials with conventional
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