oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 138 )

2018 ( 980 )

2017 ( 984 )

2016 ( 890 )

Custom range...

Search Results: 1 - 10 of 58967 matches for " Xiaoqiu Yang "
All listed articles are free for downloading (OA Articles)
Page 1 /58967
Display every page Item
Some General Inequalities for Choquet Integral  [PDF]
Xiuli Yang, Xiaoqiu Song, Leilei Huang
Applied Mathematics (AM) , 2015, DOI: 10.4236/am.2015.614201
Abstract: With the development of fuzzy measure theory, the integral inequalities based on Sugeno integral are extensively investigated. We concern on the inequalities of Choquuet integral. The main purpose of this paper is to prove the H?lder inequality for any arbitrary fuzzy measure-based Choquet integral whenever any two of these integrated functions f, g and h are comonotone, and there are three weights. Then we prove Minkowski inequality and Lyapunov inequality for Choquet integral. Moreover, when any two of these integrated functions f1, f2, , fn are comonotone, we also obtain the Hölder inequality, Minkowski inequality and Lyapunov inequality hold for Choquet integral.
Simulation on Domain Rotation Path and Magnetostriction of Terfenol-D Alloy
Jiuchun YAN,Wenbo HAN,Xiaoqiu XIE,Shiqin YANG,

材料科学技术学报 , 2001,
Abstract: Based on a simplified domain rotation model, the rotation path of internal domains and corresponding magnetostriction of 112], 111] oriented single Terfenol-D crystals under compressive prestresses have been simulated. Comparisons with results of experiment and other calculation have been made. Results of simulation showed that the 111] oriented single crystal has better low-field magnetostriction properties than the 112] oriented one. Under a compressive prestress of 10 MPa, up to 2300x10(-6) saturation magnetostriction of 111] oriented crystal has been obtained at 800 Oe, while for 112] oriented, 1600x10(-6) maximum magnetostriction has been reached at 1000 Oe.
Study on Preparation and Application in Flocculants of Modified Lignin
Haiyin Liu,Xiuyun Yang,Xiaoqiu Liu,Haibo Yao
Modern Applied Science , 2011, DOI: 10.5539/mas.v5n1p205
Abstract: The lignin sulfonate was modified with olefins monomer by the method of radiation graft polymerization, by which a new type of natural polymer flocculants can be made. And results of the flocculation and sedimentation are tested in the furfural wastewater treatment process. Furfural wastewater is a complex composition, whose COD is about 20000mg / L, is difficult to be treated by conventional methods. Our results showed that the kind of flocculants can remove 50 percent COD or more from furfural wastewater after aerating and adjusting pH value to 9.
Horizontal transfer generates genetic variation in an asexual pathogen
Xiaoqiu Huang
PeerJ , 2015, DOI: 10.7717/peerj.650
Abstract: There are major gaps in the understanding of how genetic variation is generated in the asexual pathogen Verticillium dahliae. On the one hand, V. dahliae is a haploid organism that reproduces clonally. On the other hand, single-nucleotide polymorphisms and chromosomal rearrangements were found between V. dahliae strains. Lineage-specific (LS) regions comprising about 5% of the genome are highly variable between V. dahliae strains. Nonetheless, it is unknown whether horizontal gene transfer plays a major role in generating genetic variation in V. dahliae. Here, we analyzed a previously sequenced V. dahliae population of nine strains from various geographical locations and hosts. We found highly homologous elements in LS regions of each strain; LS regions of V. dahliae strain JR2 are much richer in highly homologous elements than the core genome. In addition, we discovered, in LS regions of JR2, several structural forms of nonhomologous recombination, and two or three homologous sequence types of each form, with almost each sequence type present in an LS region of another strain. A large section of one of the forms is known to be horizontally transferred between V. dahliae strains. We unexpectedly found that 350 kilobases of dynamic LS regions were much more conserved than the core genome between V. dahliae and a closely related species (V. albo-atrum), suggesting that these LS regions were horizontally transferred recently. Our results support the view that genetic variation in LS regions is generated by horizontal transfer between strains, and by chromosomal reshuffling reported previously.
Association between Experiences and Representations: Memory, Dreaming, Dementia and Consciousness
Xiaoqiu Huang
Quantitative Biology , 2013,
Abstract: The mechanisms underlying major aspects of the human brain remain a mystery. It is unknown how verbal episodic memory is formed and integrated with sensory episodic memory. There is no consensus on the function and nature of dreaming. Here we present a theory for governing neural activity in the human brain. The theory describes the mechanisms for building memory traces for entities and explains how verbal memory is integrated with sensory memory. We infer that a core function of dreaming is to move charged particles such as calcium ions from the hippocampus to association areas to primary areas. We link a high level of calcium ions concentrations to Alzheimer's disease. We present a more precise definition of consciousness. Our results are a step forward in understanding the function and health of the human brain and provide the public with ways to keep a healthy brain.
Translational medicine as a permanent glue and force of clinical medicine and public health: perspectives (1) from 2012 Sino-American symposium on clinical and translational medicine
Jiebai Zhou, Duojiao Wu, Xinqing Liu, Shuoqi Yuan, Xiaoqiu Yang, Xiangdong Wang
Clinical and Translational Medicine , 2012, DOI: 10.1186/2001-1326-1-21
Abstract: Clinical and translational medicine (CTM) has been highly emphasized since Dr. Elias Zerhouni, the former director of the National Institutes of Health, proposed “The NIH Roadmap” in 2003 [1]. CTM is an emerging area comprising multidisciplinary research from basic sciences to medical applications and entails a close collaboration between clinicians and basic scientists across institutes. It is further defined as a two-way road: bench-to-bedside and bedside-to-bench [2], to translate discoveries from the bench into clinical application and/or the translation of clinical findings into the understanding of molecular mechanisms. CTM was emphasized to play a unique and critical role in optimizing new biotechnologies, improving clinical application of new therapeutic concepts, and ultimately improving the quality of life for patients [3]. The emergence of translational science highlights the unifying framework that bridges the continuum of knowledge creation and deployment, converting fundamental discoveries to human application, advancing the information into clinical practice, disseminating best clinical practices into communities and, ultimately, modifying the behavior of populations to improve global health [4].It is of great significance to promote CTM among clinicians, basic researchers, biotechnologists, politicians, ethicists, sociologists, or investors and coordinate these efforts among different countries [5]. CTM as an inter-disciplinary science is developing widely and become a global priority. The 2012 Sino-American Symposium on Clinical and Translational Medicine (SAS-CTM) as one of milestone conferences on CTM was organized by Chinese Academy of Engineering, Chinese Academy of Medical Sciences, The U.S. National Institutes of Health Clinical Center, and GlobalMD Organization. The SAS-CTM was established as a bridge between China and the U.S. to exchange ideas on clinical and translational research, built up the highest level and most influential collaborat
Severe Maternal Hyperglycemia Exacerbates the Development of Insulin Resistance and Fatty Liver in the Offspring on High Fat Diet
Yong Song,Jibin Li,Yong Zhao,Qijuan Zhang,Zhiguo Liu,Jingna Li,Xiaoyi Chen,Zhu Yang,Chao Yu,Xiaoqiu Xiao
Experimental Diabetes Research , 2012, DOI: 10.1155/2012/254976
Abstract: Background. Adverse maternal environments may predispose the offspring to metabolic syndrome in adulthoods, but the underlying mechanism has not been fully understood. Methods. Maternal hyperglycemia was induced by streptozotocin (STZ) injection while control (CON) rats received citrate buffer. Litters were adjusted to eight pups per dam and then weaned to standard diet. Since 13 weeks old, a subset of offspring from STZ and CON dams were switched to high fat diet (HFD) for another 13 weeks. Glucose and insulin tolerance tests (GTT and ITT) and insulin secretion assay were performed; serum levels of lipids and leptin were measured. Hepatic fat accumulation and islet area were evaluated through haematoxylin and eosin staining. Results. STZ offspring exhibited lower survival rate, lower birth weights, and growth inhibition which persisted throughout the study. STZ offspring on HFD showed more severe impairment in GTT and ITT, and more profound hepatic steatosis and more severe hyperlipidemia compared with CON-HFD rats. Conclusions. Offspring from diabetic dams would be prone to exhibit low birth weight and postnatal growth inhibition, but could maintain normal glucose tolerance and insulin sensitivity. HFD accelerates development of insulin resistance in the offspring of diabetic dams mainly via a compensatory response of islets.
A Genome-Wide Survey of Highly Expressed Non-Coding RNAs and Biological Validation of Selected Candidates in Agrobacterium tumefaciens
Keunsub Lee, Xiaoqiu Huang, Chichun Yang, Danny Lee, Vincent Ho, Kan Nobuta, Jian-Bing Fan, Kan Wang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0070720
Abstract: Agrobacterium tumefaciens is a plant pathogen that has the natural ability of delivering and integrating a piece of its own DNA into plant genome. Although bacterial non-coding RNAs (ncRNAs) have been shown to regulate various biological processes including virulence, we have limited knowledge of how Agrobacterium ncRNAs regulate this unique inter-Kingdom gene transfer. Using whole transcriptome sequencing and an ncRNA search algorithm developed for this work, we identified 475 highly expressed candidate ncRNAs from A. tumefaciens C58, including 101 trans-encoded small RNAs (sRNAs), 354 antisense RNAs (asRNAs), 20 5′ untranslated region (UTR) leaders including a RNA thermosensor and 6 riboswitches. Moreover, transcription start site (TSS) mapping analysis revealed that about 51% of the mapped mRNAs have 5′ UTRs longer than 60 nt, suggesting that numerous cis-acting regulatory elements might be encoded in the A. tumefaciens genome. Eighteen asRNAs were found on the complementary strands of virA, virB, virC, virD, and virE operons. Fifteen ncRNAs were induced and 7 were suppressed by the Agrobacterium virulence (vir) gene inducer acetosyringone (AS), a phenolic compound secreted by the plants. Interestingly, fourteen of the AS-induced ncRNAs have putative vir box sequences in the upstream regions. We experimentally validated expression of 36 ncRNAs using Northern blot and Rapid Amplification of cDNA Ends analyses. We show functional relevance of two 5′ UTR elements: a RNA thermonsensor (C1_109596F) that may regulate translation of the major cold shock protein cspA, and a thi-box riboswitch (C1_2541934R) that may transcriptionally regulate a thiamine biosynthesis operon, thiCOGG. Further studies on ncRNAs functions in this bacterium may provide insights and strategies that can be used to better manage pathogenic bacteria for plants and to improve Agrobacterum-mediated plant transformation.
Severe Maternal Hyperglycemia Exacerbates the Development of Insulin Resistance and Fatty Liver in the Offspring on High Fat Diet
Yong Song,Jibin Li,Yong Zhao,Qijuan Zhang,Zhiguo Liu,Jingna Li,Xiaoyi Chen,Zhu Yang,Chao Yu,Xiaoqiu Xiao
Journal of Diabetes Research , 2012, DOI: 10.1155/2012/254976
Abstract: Background. Adverse maternal environments may predispose the offspring to metabolic syndrome in adulthoods, but the underlying mechanism has not been fully understood. Methods. Maternal hyperglycemia was induced by streptozotocin (STZ) injection while control (CON) rats received citrate buffer. Litters were adjusted to eight pups per dam and then weaned to standard diet. Since 13 weeks old, a subset of offspring from STZ and CON dams were switched to high fat diet (HFD) for another 13 weeks. Glucose and insulin tolerance tests (GTT and ITT) and insulin secretion assay were performed; serum levels of lipids and leptin were measured. Hepatic fat accumulation and islet area were evaluated through haematoxylin and eosin staining. Results. STZ offspring exhibited lower survival rate, lower birth weights, and growth inhibition which persisted throughout the study. STZ offspring on HFD showed more severe impairment in GTT and ITT, and more profound hepatic steatosis and more severe hyperlipidemia compared with CON-HFD rats. Conclusions. Offspring from diabetic dams would be prone to exhibit low birth weight and postnatal growth inhibition, but could maintain normal glucose tolerance and insulin sensitivity. HFD accelerates development of insulin resistance in the offspring of diabetic dams mainly via a compensatory response of islets. 1. Introduction Metabolic syndrome (MetS) is a clustering of metabolic disorders including hyperglycemia, hypertension, dyslipidemia, overweight, and central obesity, with insulin resistance as the central feature of this syndrome [1]. A global increase in the prevalence of MetS has been found in the last decades due to the worldwide epidemic of obesity [2, 3]. The risk of the MetS depends on genetic susceptibility but is modulated by pre- and postnatal environmental factors. A growing body of evidence suggests that adverse environmental conditions during crucial periods of development may predispose individuals to develop different components of the MetS in adulthood [4]. Of particular note is maternal diabetes, including type 1 and type 2 diabetes and gestational diabetes mellitus (GDM). An overall increasing prevalence of diabetes indicates an emergence of diabetes among childbearing women. During pregnancy, especially during critical window periods for organogenesis and fetal development, unsatisfactory glycemic control is known to increase the incidence of severe obstetrical complications, including preeclampsia, macrosomia, and Caesarean section. Additionally, intrauterine exposure to a hyperglycemic environment predisposes
A method for finding single-nucleotide polymorphisms with allele frequencies in sequences of deep coverage
Jianmin Wang, Xiaoqiu Huang
BMC Bioinformatics , 2005, DOI: 10.1186/1471-2105-6-220
Abstract: We describe a computational method for finding common SNPs with allele frequencies in single-pass sequences of deep coverage. The method enhances a widely used program named PolyBayes in several aspects. We present results from our method and PolyBayes on eighteen data sets of human expressed sequence tags (ESTs) with deep coverage. The results indicate that our method used almost all single-pass sequences in computation of the allele frequencies of SNPs.The new method is able to handle single-pass sequences of deep coverage efficiently. Our work shows that it is possible to analyze sequences of deep coverage by using pairwise alignments of the sequences with the finished genome sequence, instead of multiple sequence alignments.Information concerning the allele frequencies of single-nucleotide polymorphisms (SNPs) is needed to select an optimal subset of common SNPs for use in association studies [1]. One approach to finding common SNPs with allele frequencies is to generate DNA sequences from a sufficient number of samples in a population. This approach requires that computational methods have an ability to handle thousands of sequences from the same genome location (sequences of deep coverage). In this paper, we describe a computational method for finding common SNPs with allele frequencies in sequences of deep coverage. We present results from the method on human expressed sequence tags (ESTs) of deep coverage, which are currently a major source of DNA sequences of deep coverage. The method is also expected to be useful for finding common mutations in sequences of deep coverage produced in a cancer genome project [2].The PolyBayes program is widely used to find SNPs in redundant DNA sequences [3,4]. It first constructs a multiple sequence alignment based on pairwise alignments of each sequence with a high-quality genomic sequence called an anchor. Then it identifies and removes paralogous sequences that have a high number of observed differences with the anchor s
Page 1 /58967
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.