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Search Results: 1 - 10 of 6041 matches for " XAVIER;SANCHO-BIELSA "
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The lizard cerebral cortex as a model to study neuronal regeneration
LOPEZ-GARCIA, CARLOS;MOLOWNY, ASUNCION;NACHER, JUAN;PONSODA, XAVIER;SANCHO-BIELSA, FRANCISCO;ALONSO-LLOSA, GREGORI;
Anais da Academia Brasileira de Ciências , 2002, DOI: 10.1590/S0001-37652002000100006
Abstract: the medial cerebral cortex of lizards, an area homologous to the hippocampal fascia dentata, shows delayed postnatal neurogenesis, i.e., cells in the medial cortex ependyma proliferate and give rise to immature neurons, which migrate to the cell layer. there, recruited neurons differentiate and give rise to zinc containing axons directed to the rest of cortical areas, thus resulting in a continuous growth of the medial cortex and its zinc-enriched axonal projection. this happens along the lizard life span, even in adult lizards, thus allowing one of their most important characteristics: neuronal regeneration. experiments in our laboratory have shown that chemical lesion of the medial cortex (affecting up to 95% of its neurons) results in a cascade of events: first, massive neuronal death and axonal-dendritic retraction and, secondly, triggered ependymal-neuroblast proliferation and subsequent neo-histogenesis and regeneration of an almost new medial cortex, indistinguishable from a normal undamaged one. this is the only case to our knowledge of the regeneration of an amniote central nervous centre by new neuron production and neo-histogenesis. thus the lizard cerebral cortex is a good model to study neuronal regeneration and the complex factors that regulate its neurogenetic, migratory and neo-synaptogenetic events.
Neurons of the Dentate Molecular Layer in the Rabbit Hippocampus
Francisco J. Sancho-Bielsa,Juan D. Navarro-López,Gregori Alonso-Llosa,Asunción Molowny,Xavier Ponsoda,Javier Yajeya,Carlos López-García
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0048470
Abstract: The molecular layer of the dentate gyrus appears as the main entrance gate for information into the hippocampus, i.e., where the perforant path axons from the entorhinal cortex synapse onto the spines and dendrites of granule cells. A few dispersed neuronal somata appear intermingled in between and probably control the flow of information in this area. In rabbits, the number of neurons in the molecular layer increases in the first week of postnatal life and then stabilizes to appear permanent and heterogeneous over the individuals’ life span, including old animals. By means of Golgi impregnations, NADPH histochemistry, immunocytochemical stainings and intracellular labelings (lucifer yellow and biocytin injections), eight neuronal morphological types have been detected in the molecular layer of developing adult and old rabbits. Six of them appear as interneurons displaying smooth dendrites and GABA immunoreactivity: those here called as globoid, vertical, small horizontal, large horizontal, inverted pyramidal and polymorphic. Additionally there are two GABA negative types: the sarmentous and ectopic granular neurons. The distribution of the somata and dendritic trees of these neurons shows preferences for a definite sublayer of the molecular layer: small horizontal, sarmentous and inverted pyramidal neurons are preferably found in the outer third of the molecular layer; vertical, globoid and polymorph neurons locate the intermediate third, while large horizontal and ectopic granular neurons occupy the inner third or the juxtagranular molecular layer. Our results reveal substantial differences in the morphology and electrophysiological behaviour between each neuronal archetype in the dentate molecular layer, allowing us to propose a new classification for this neural population.
Relationship between sunspot number and total annual precipitation at Izana (Tenerife): Maximum precipitation prediction with three year lagged sunspots?
Xavier Calbet,Maria Carmen Romero,Juan Manuel Sancho,Pilar Ripodas,Victor Jesus Quintero
Physics , 2001,
Abstract: A possible relationship between sunspot number and total annual precipitation from the Izana Observatory has been found. The annual precipitation period ranges from 1916 to 1998, thus including nearly eight 11-year solar cycles. When points of total precipitation for a given year at Izana are plotted on the ordinate axis versus the yearly sunspot number on the abcisa axis three years back from the precipitation one, nearly all of them lie in the lower left hand corner of the diagram. This seems to indicate a relationship between the above mentioned variables. If this relationship is confirmed it would permit the prediction of a maximum annual precipitation at Izana three years in advance.
A Direct Proof of the Theorem on Formal Functions
Fernado Sancho,Pedro Sancho
Mathematics , 2007,
Abstract: We give a direct and elementary proof of the theorem on formal functions by studying the behaviour of the Godement resolution of a sheaf of modules under completion.
Elucidating General Equilibrium Multiplier Effects: A Differential Perspective  [PDF]
M. Alejandro Cardenete, Ferran Sancho
Theoretical Economics Letters (TEL) , 2013, DOI: 10.4236/tel.2013.35046
Abstract: Expenditure multipliers are routinely used to evaluate the effectiveness of government spending. When interested in disaggregated effects, interindustry models provide the necessary tools to be able to look at very detailed sectorial results. These models are theoretically simple and empirically operational, which makes them easily implementable and therefore popular with policy makers. They miss, however, quite a bit of the interaction that takes place at the micro level. On the one hand, they ignore the role exerted by supply constraints in primary factors; on the other hand, they look at the world as though it is fully linear. We overcome these limitations by using an opposite Walrasian general equilibrium model to compute marginal multipliers. By using differential calculus, we also offer some insights regarding the “under-the-hood” circuits of influence.
Statistical methods for the information professional. A practical, painless approach to understanding, using and interpreting statistics (Liwen Vaughan)
Sancho, Rosa
Revista Espa?ola de Documentación Científica , 2001,
Abstract:
Informe del V taller iberoamericano de indicadores de ciencia y tecnología
Sancho, Rosa
Revista Espa?ola de Documentación Científica , 2001,
Abstract:
Congreso Internacional de Información INFO2008 y IV Seminario Internacional sobre Estudios Cuantitativos y Cualitativos de la Ciencia y la Tecnología Gilberto Sotolongo Aguilar
Sancho, Rosa
Revista Espa?ola de Documentación Científica , 2008,
Abstract:
I Jornadas espa olas de indicadores para la evaluación de la ciencia y la tecnología
Sancho, Rosa
Revista Espa?ola de Documentación Científica , 2005,
Abstract:
Innovación industrial
Sancho, Rosa
Revista Espa?ola de Documentación Científica , 2007,
Abstract: A study about the state of the art of definitions, theories and patterns of innovation processes is presented. The process of development of industrial innovation as well as the more commonly used indicators are analysed. The harmonized surveys used in industrialized countries to obtain innovation statistics and indicators are presented. Se presentan las definiciones, teorías y modelos del proceso de innovación industrial y su evolución a lo largo del tiempo. Se analiza históricamente el proceso del desarrollo de la innovación en la industria y los indicadores de innovación más comúnmente empleados. Se exponen las encuestas normalizadas que se utilizan en los países industrializados para obtener las estadísticas e indicadores de innovación.
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