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Search Results: 1 - 10 of 34603 matches for " Weizhong Lu "
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Cholangiocarcinoma Arising 38 Years after Surgical Resection of Hepatocellular Carcinoma  [PDF]
Jianguo Chen, Weizhong Lu, Lianxin Wang, Yixin Zhang, Nengjin Wang, Yongsheng Chen, Jian Zhu, Hongwei Zheng, Jun Yang, Fei Chen
Journal of Cancer Therapy (JCT) , 2013, DOI: 10.4236/jct.2013.45107

Background: Most of the reports on tumor relapse are recurrence of the same type of tumor after months to few years of a successful initial cancer treatment. It is generally unusual and unexpected that a different type of the second tumor occurs after several decades of the curative treatment of the original tumor. Case Presentation: We report a case of 74-year-old man with intrahepatic cholangiocarcinoma (ICC) diagnosed 38 years after curative resection of hepatocellular carcinoma (HCC). In addition to the uniqueness of longer survival and developed a new type of tumor, both the original HCC and the later occurred ICC were detected through a cancer surveillance program by screening alpha-fetoprotein (AFP) and ultrasonography of the liver for the general population and/or high risk group of people who were asymptomatic. Conclusion: This report provides evidence demonstrating occurrence of new type of tumor following initial curative therapy of the original tumor. In addition, this case report also highlights the importance of cancer surveillance program for earlier detection of the tumors to achieve a remarkably improved prognosis of the cancer patients for a prolonged cancer free survival time.

Developing Human Capital Capabilities of Top Management Team for CoPS Innovation  [PDF]
Yuhui GE, Weizhong YANG
Journal of Service Science and Management (JSSM) , 2009, DOI: 10.4236/jssm.2009.23027
Abstract: Top management team (TMT) play key roles in many industries and firms. Human resources is continuously developed and considered to be a competitive advantage. Traditional research on TMT has, however, paid scant attention to the human capital capabilities of TMT needed for firms. Furthermore, traditional work on TMT of firms pays limited attention to its specific traits in complex products and systems (CoPS) innovation. In the present paper, we explore the development of human capabilities of TMT observed in CoPS innovation firms. We developed a model for analysis the human capital capabilities of TMT for CoPS Innovation, and suggested that a dynamic interplay between the development of human capital capabilities of TMT and the changing CoPS innovation environment, and human capital capabilities of TMT for CoPS innovation could be developed through team learning. And we formulated an empirical research framework for the analysis of factors affecting the human capital capabilities of TMT for CoPS innovation. Four key factors were identified and extracted by using factor analysis, and these resulting factors were related to the performance of CoPS innovation by using a multiple regression analysis method. The proposed framework identified four blocks of human capital capabilities of TMT for CoPS innovation, namely technology innovation management, risk management, organization management and relationship network management. The paper argues that TMT for CoPS innovation firms are only able to effectively harness and develop their human capital capabilities by team learning and integrating these four building blocks within the team.
Time series analysis of dengue fever and weather in Guangzhou, China
Liang Lu, Hualiang Lin, Linwei Tian, Weizhong Yang, Jimin Sun, Qiyong Liu
BMC Public Health , 2009, DOI: 10.1186/1471-2458-9-395
Abstract: Time series Poisson regression analysis was performed using data on monthly weather variables and monthly notified cases of dengue fever in Guangzhou, China for the period of 2001-2006. Estimates of the Poisson model parameters was implemented using the Generalized Estimating Equation (GEE) approach; the quasi-likelihood based information criterion (QICu) was used to select the most parsimonious model.Two best fitting models, with the smallest QICu values, are selected to characterize the relationship between monthly dengue incidence and weather variables. Minimum temperature and wind velocity are significant predictors of dengue incidence. Further inclusion of minimum humidity in the model provides a better fit.Minimum temperature and minimum humidity, at a lag of one month, are positively associated with dengue incidence in the subtropical city of Guangzhou, China. Wind velocity is inversely associated with dengue incidence of the same month. These findings should be considered in the prediction of future patterns of dengue transmission.Dengue fever is an arboviral disease transmitted by mosquitoes in tropical and subtropical areas around the world. It is caused by one of four closely related but antigenically distinct virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4) of the genus Flavivirus [1]. In terms of the number of human infections occurring globally, dengue fever is considered to be the most important arthropod-borne viral disease in humans; currently, more than 2.5 billion people live in high risk areas of dengue fever [2].In China, outbreaks of dengue-like illness were not uncommon in the 1940s although etiological and epidemiological investigations were not carried out. Outbreaks of dengue-like illness were not reported in China during 1950-1978. An outbreak of dengue fever due to DEN-4 virus occurred in Foshan City of Guangdong Province in 1978 [3]. Since then, dengue occurred frequently in southern China, including Guangdong, Guangxi, Hainan, Taiwan, F
Analysis and comparison of very large metagenomes with fast clustering and functional annotation
Weizhong Li
BMC Bioinformatics , 2009, DOI: 10.1186/1471-2105-10-359
Abstract: The new metagenomic data analysis method Rapid Analysis of Multiple Metagenomes with a Clustering and Annotation Pipeline (RAMMCAP) was developed using an ultra-fast sequence clustering algorithm, fast protein family annotation tools, and a novel statistical metagenome comparison method that employs a unique graphic interface. RAMMCAP processes extremely large datasets with only moderate computational effort. It identifies raw read clusters and protein clusters that may include novel gene families, and compares metagenomes using clusters or functional annotations calculated by RAMMCAP. In this study, RAMMCAP was applied to the two largest available metagenomic collections, the "Global Ocean Sampling" and the "Metagenomic Profiling of Nine Biomes".RAMMCAP is a very fast method that can cluster and annotate one million metagenomic reads in only hundreds of CPU hours. It is available from http://tools.camera.calit2.net/camera/rammcap/ webcite.The emerging field of metagenomics enables a more comprehensive understanding of environmental microbial communities [1-9]. However, metagenomic data consists of enormous numbers of fragmented sequences that challenge data analysis methodologically and computationally. To address these challenges, new methods and resources have been developed, such as simulated datasets[10], IMG/M[11], CAMERA[12], MG-RAST[13], taxonomy tools[14,15], statistical comparison[16], functional diversity analysis[17], binning [18-20] and so on.The Rapid Analysis of Multiple Metagenomes with a Clustering and Annotation Pipeline (RAMMCAP) presented herein aims to address the particular computational challenges imposed by the huge size and great diversity of metagenomic data. The primary goal is to significantly reduce the computational effort in sequence comparison, as large-scale comparison of metagenomic sequences has become extremely time-consuming. For example, the protein analysis of the Global Ocean Sampling (GOS) study[2] took more than one million
Variability of Bio-Clinical Parameters in Chinese-Origin Rhesus Macaques Infected with Simian Immunodeficiency Virus: A Nonhuman Primate AIDS Model
Song Chen,Chunhui Lai,Xiaoxiang Wu,Yaozheng Lu,Daishu Han,Weizhong Guo,Linchun Fu,Jean-Marie Andrieu,Wei Lu
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0023177
Abstract: Although Chinese-origin Rhesus macaques (Ch RhMs) infected with simian immunodeficiency virus (SIV) have been used for many years to evaluate the efficacy of AIDS vaccines and therapeutics, the bio-clinical variability of such a nonhuman primate AIDS model was so far not established.
Heat exchange at air-sea interface in the South China Sea during monsoon periods in 1986
Disheng Wu,Weizhong Feng,Jianping Xu,Jinghua Yan,Xue Zhao,Shuihua Zhou,Jiwei Zhang,Guanyu Qiao,Fu Lin,Boming Lu
Chinese Science Bulletin , 2006, DOI: 10.1007/s11434-006-2123-z
Abstract: In order to explore the interaction between the sea and monsoon in the South China Sea, the heat exchanges at air-sea interface during monsoon periods in 1986 were calculated using observational data. It shows that when the summer monsoon bursts and prevails over the South China Sea, the air-sea interface heat exchange is strong and the latent heat rises rapidly in the intertropical convergence zone and the tropic cyclone system near 20.49°N, 114.14°E. On May 24, 1986, the sensible heat became positive in the typhoon system. The heating exchange indicates that heat is transported from ocean to atmosphere, with major contribution of latent heat. When the summer monsoon prevails over the South China Sea and the weather is fine, even SST (sea surface temperature) is high, but sensible heat appears to be negative. The heat exchange indicates that heat is transported from atmosphere to ocean, with major contribution of short-wave radiation absorbed by sea surface and sensible heat. When summer monsoon is over and the northeast monsoon prevails over the South China Sea, the heat exchange at air-sea interface is very strong. The heating exchange shows that the ocean heats the atmosphere, with major contribution of latent heat when cold air arrives at the sea surface and the sensible heat rises to positive rapidly. Therefore it can be concluded that the heat exchange at air-sea interface is different from the SST in South China Sea. When the summer monsoon prevails over the South China Sea, the main trend is the ocean responding to the atmosphere.
Diurnal Cycle of the North American Monsoon in a Mesoscale Model Simulation: Evolution of Key Parameters in Relation to Precipitation
Bin Guan,Weizhong Zheng
Atmosphere , 2011, DOI: 10.3390/atmos2020057
Abstract: The diurnal cycle of the North American monsoon is analyzed based on the output from a mesoscale model simulation. Statistically significant diurnal cycle in precipitation is identified, with heavy precipitation—essentially convective—dominating in local afternoons. Temporal evolution of key parameters in relation to precipitation is investigated, based on which a sequence of the dynamic/thermodynamic processes underlying precipitation development is proposed. Particularly, the afternoon peak in precipitation is found preceded by enhanced static instability and low-level convergence.
Auto-amplifying dynamic behavior of heap and convection in granular material
Weizhong Chen,Rongjue Wei
Chinese Science Bulletin , 1998, DOI: 10.1007/BF02883565
Abstract: Two experiments have been carried out to understand the physical characteristics of surface heap and internal convection of granular material subjected to vertical vibration. The results show that they have a clear auteamplifying behavior. An effective force leading to the heap and cunvection has been obtained, which includes the square and cubic terms of the local height.
On Farmer’s Willingness to Small Forest Tenure Mortgage Loans —A Case Study on Yibin of Sichuan
Xin Cai,Weizhong Zeng
International Journal of Business and Management , 2011, DOI: 10.5539/ijbm.v6n3p272
Abstract: Based on the survey data of 364 peasant households in Yibin, Sichuan, this paper analyzes the farmer’s willingness to small forest tenure mortgage loans. The result indicates a high willingness up to 74.2%, i.e. the farmers are willing to invest forest tenure mortgage loans into forestry and agricultural production. The influential factors on farmer’s willingness to small forest tenure mortgage loans include age, education, forest area, the main source of family income, perception on the policies of forest tenure mortgage loans, social services of forestry, financial institutions, etc. We propose the policy advocacy of forest tenure mortgage loans be enhanced, mortgage loans of different period be designed for different purposes, and discount policy on small mortgage loans be issued.
Molecular Epidemiology of Human Immunodeficiency Virus Type 1 in Guangdong Province of Southern China
Song Chen,Weiping Cai,Jingyang He,Nicole Vidal,Chunhui Lai,Weizhong Guo,Haolan He,Xiejie Chen,Linsheng Fu,Martine Peeters,Eric Delaporte,Jean-Marie Andrieu,Wei Lu
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0048747
Abstract: Although the outbreak of human immunodeficiency virus type 1 (HIV-1) in Guangdong has been documented for more than a decade, the molecular characteristics of such a regional HIV-1 epidemic remained unknown.
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