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Search Results: 1 - 10 of 78078 matches for " Weiliang Chen "
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Chen Longxun,Li Weiliang,

大气科学进展 , 1985,
Abstract: For better understanding the mechanism of monsoon formation and designing the numerical simulation of the general atmospheric circulation, a new approach of calculating atmospheric radiation is proposed to investigate the distribution of the atmospheric heat source, and the budget of heat component is recalculated. The results show that there is a tremendous atmospheric heat source region over central India, northeast of the Bay of Bengal, east of the South China Sea and about 10 °N at the west Pacific, among which the heating center with a maximum heating rate of 8 °C/day is located over the Bay of Bengal and the average rate in the Plateau is about 1 °C/day.
Python-based geometry preparation and simulation visualization toolkits for STEPS
Weiliang Chen,Erik De Schutter
Frontiers in Neuroinformatics , 2014, DOI: 10.3389/fninf.2014.00037
Abstract: STEPS is a stochastic reaction-diffusion simulation engine that implements a spatial extension of Gillespie's Stochastic Simulation Algorithm (SSA) in complex tetrahedral geometries. An extensive Python-based interface is provided to STEPS so that it can interact with the large number of scientific packages in Python. However, a gap existed between the interfaces of these packages and the STEPS user interface, where supporting toolkits could reduce the amount of scripting required for research projects. This paper introduces two new supporting toolkits that support geometry preparation and visualization for STEPS simulations.
Chemical Reaction and Crystalline Procedure of Bismuth Titanate Nanoparticles Derived by Metalorganic Decomposition Technique  [PDF]
Weiliang Liu, Xinqiang Wang, Dong Tian, Chenglong Xiao, Zengjiang Wei, Shouhua Chen
Materials Sciences and Applications (MSA) , 2010, DOI: 10.4236/msa.2010.12016
Abstract: The homogeneous bismuth titanate single-phase nanoscaled ceramic powders have been prepared by means of metalorganic decomposition. The thermal decomposition/oxidation of the preheated precursor, as investigated by differential thermalgravimetric analysis, X-ray powder diffraction, and environment scanning electron microscope, lead to the formation of a well-defined orthorhombic bismuth titanate compound. Formation of the layered perovskite-like bismuth titanate occurs via intermediates with sequential changes in the coordination polyhedron of bismuth. The chemical reactions of precursor powder in heat treatment process have been investigated further by Raman and Fourier transform infrared spectra, and the reaction mechanism was tentatively proposed thereafter.
A New Corrosion Sensor to Determine the Start and Development of Embedded Rebar Corrosion Process at Coastal Concrete
Chen Xu,Zhiyuan Li,Weiliang Jin
Sensors , 2013, DOI: 10.3390/s131013258
Abstract: The corrosion of reinforcements induced by chloride has resulted to be one of the most frequent causes of their premature damage. Most corrosion sensors were designed to monitor corrosion state in concrete, such as Anode-Ladder-System and Corrowatch System, which are widely used to monitor chloride ingress in marine concrete. However, the monitoring principle of these corrosion sensors is based on the macro-cell test method, so erroneous information may be obtained, especially from concrete under drying or saturated conditions due to concrete resistance taking control in macro-cell corrosion. In this paper, a fast weak polarization method to test corrosion state of reinforcements based on electrochemical polarization dynamics was proposed. Furthermore, a new corrosion sensor for monitoring the corrosion state of concrete cover was developed based on the proposed test method. The sensor was tested in cement mortar, with dry-wet cycle tests to accelerate the chloride ingress rate. The results show that the corrosion sensor can effectively monitor chloride penetration into concrete with little influence of the relative humidity in the concrete. With a reasonable corrosion sensor electrode arrangement, it seems the Ohm-drop effect measured by EIS can be ignored, which makes the tested electrochemical parameters more accurate.
Binding Modes of Three Inhibitors 8CA, F8A and I4A to A-FABP Studied Based on Molecular Dynamics Simulation
Jianzhong Chen, Jinan Wang, Weiliang Zhu
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0099862
Abstract: Adipocyte fatty-acid binding protein (A-FABP) is an important target of drug designs treating some diseases related to lipid-mediated biology. Molecular dynamics (MD) simulations coupled with solvated interaction energy method (SIE) were carried out to study the binding modes of three inhibitors 8CA, F8A and I4A to A-FABP. The rank of our predicted binding affinities is in accordance with experimental data. The results show that the substitution in the position 5 of N-benzyl and the seven-membered ring of N-benzyl-indole carboxylic acids strengthen the I4A binding, while the substitution in the position 2 of N-benzyl weakens the F8A binding. Computational alanine scanning and dynamics analyses were performed and the results suggest that the polar interactions of the positively charged residue R126 with the three inhibitors provide a significant contribution to inhibitor bindings. This polar interaction induces the disappearance of the correlated motion of the C terminus of A-FABP relative to the N terminus and favors the stability of the binding complex. This study is helpful for the rational design of potent inhibitors within the fields of metabolic disease, inflammation and atherosclerosis.
Manifesting pseudo-spin polarization on the edge of graphene via field emission image
Jingkun Chen,Zhibing Li,Weiliang Wang
Physics , 2013, DOI: 10.1063/1.4863726
Abstract: We obtain the wave function of field emission from graphene in magnetic field. The emission image reveals structure of the Landau levels and depends on the phase difference between two sub-lattices. The emission pattern is sensitive to the edge potential shift, so a gate voltage can manipulate that.
STEPS: efficient simulation of stochastic reaction–diffusion models in realistic morphologies
Iain Hepburn, Weiliang Chen, Stefan Wils, Erik De Schutter
BMC Systems Biology , 2012, DOI: 10.1186/1752-0509-6-36
Abstract: We describe STEPS, a stochastic reaction–diffusion simulator developed with an emphasis on simulating biochemical signaling pathways accurately and efficiently. STEPS supports all the above-mentioned features, and well-validated support for SBML allows many existing biochemical models to be imported reliably. Complex boundaries can be represented accurately in externally generated 3D tetrahedral meshes imported by STEPS. The powerful Python interface facilitates model construction and simulation control. STEPS implements the composition and rejection method, a variation of the Gillespie SSA, supporting diffusion between tetrahedral elements within an efficient search and update engine. Additional support for well-mixed conditions and for deterministic model solution is implemented. Solver accuracy is confirmed with an original and extensive validation set consisting of isolated reaction, diffusion and reaction–diffusion systems. Accuracy imposes upper and lower limits on tetrahedron sizes, which are described in detail. By comparing to Smoldyn, we show how the voxel-based approach in STEPS is often faster than particle-based methods, with increasing advantage in larger systems, and by comparing to MesoRD we show the efficiency of the STEPS implementation.STEPS simulates models of cellular reaction–diffusion systems with complex boundaries with high accuracy and high performance in C/C++, controlled by a powerful and user-friendly Python interface. STEPS is free for use and is available at http://steps.sourceforge.net/ webciteAs the understanding of the molecular systems governing many aspects of cellular function improves it is becoming increasingly clear that the assumption of mass action kinetics in well-mixed volumes is often invalid. A good example is calcium signaling, which can be highly localized with very steep concentration gradients [1-3]. Calcium signaling depends on the interaction between membranes where the calcium channels are located and the cytoplas
Clustering Predicts Memory Performance in Networks of Spiking and Non-Spiking Neurons
Weiliang Chen,Reinoud Maex,Volker Steuber,Neil Davey
Frontiers in Computational Neuroscience , 2011, DOI: 10.3389/fncom.2011.00014
Abstract: The problem we address in this paper is that of finding effective and parsimonious patterns of connectivity in sparse associative memories. This problem must be addressed in real neuronal systems, so that results in artificial systems could throw light on real systems. We show that there are efficient patterns of connectivity and that these patterns are effective in models with either spiking or non-spiking neurons. This suggests that there may be some underlying general principles governing good connectivity in such networks. We also show that the clustering of the network, measured by Clustering Coefficient, has a strong negative linear correlation to the performance of associative memory. This result is important since a purely static measure of network connectivity appears to determine an important dynamic property of the network.
Cloning and analysis of the antagonistic related genes of Enterobacter cloacae B8
Xuping Yu,Junli Zhu,Xunping Yao,Shicheng He,Haining Huang,Weiliang Chen,Debao Li
Chinese Science Bulletin , 2004, DOI: 10.1360/04wc0011
Abstract: To understand the antagonistic mechanism of the broad spectrum antagonistic Enterobacter cloacae B8, Tn5 transposon-mediated mutagenesis is performed using suicide plasmid pZJ25. Two mutant strains that lost antagonistic character are isolated. Tagging with kan r gene on Tn5, an antagonistic related DNA fragment, the F fragment, right of the Tn5 insertion site is cloned in a plasmid named pTLF, from one of the mutant strains B8F. The 735 bp F fragment is then sequenced after subcloning. Genomic DNA of the original B8 strain is isolated, digested with Pst I and ligated to Pst I cassette. DNA fragments left and right of the F fragment are amplified from the Pst I cassette library using cassette primer and specific primers designed according to known sequence. 1106 bp sequence left of the F fragment and 664bp sequence right of the F fragment are finally obtained. Bioinformatics analysis shows that the contig assembled from the sequences of the cloned antagonistic related DNA fragments of B8 encodes three ORFs and is homogeneous to admM, admN and admO genes of Pantoea agglomerans andrimid biosynthetic gene cluster (AY192157). The ORF, named anrF gene which encodes a polyketide synthase, knocked out by Tn5 insertion, is a homology of admM and the insertion site of Tn5 is at 214 bp upstream of the stop codon. It is concluded that the anrF gene is a gene related to the antagonistic activity of E. cloacae B8, and speculated that the antagonistic substance produced by B8 is an andrimid.
Pollination ecology of cultivated Ficus pumila var.awkeotsang

CHEN Yong,LI Hongqing,MA Weiliang,

应用生态学报 , 2006,
Abstract: The study on the pollination ecology of cultivated Ficus pumila var. awkeotsang showed that this plant had two apparent blossoming periods, i.e., in spring and autumn, which were relatively longer than those of the wild one. Cultivated Ficus pumila var. awkeotsang couldnt rely on the wasps living in the variant syconia to pollinate or lay eggs. Under the circumstances the wasps were separated from wild F. pumila var. awkeotsang, the pollination system was damaged because of the absence of the wasps. The pollination wasps could be introduced artificially to cultivated F. pumila var. awkeotsang, but the pollination system was restored relatively slowly. The rate of syconia hanging on trees could only reach 51.11% after four years, with an average production rate of the female flowers being 64.37%, and an average gall tuming rate of gall flowers being 64.35%. The growing syconia degree of female and male flowering phases was low, and the collective way of the wasps' flying out and the small number of the wasps entering the syconia were the causes of low rate co-existing breeding.
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