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Search Results: 1 - 10 of 70952 matches for " Wei Shi "
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Mechanism Analysis of Coal Mine Entrepreneurial Social Capital  [PDF]
Ping Wang, Wei Shi
Technology and Investment (TI) , 2012, DOI: 10.4236/ti.2012.33021
Abstract: This paper first focuses on the concept of coal entrepreneurial social capital under the background of safety production; Then, analyzes the source of coal entrepreneurial social capital and their action mechanism in order to improve the performance of safety and economy; Finally, this article puts forward the possible application safety production fields and its prospect of entrepreneurial social capital in coal mine enterprise and safety in production.
A Novel Design of Fuzzy PID Controllers for Dual-Sensor Cardiac Pacemaker Systems  [PDF]
Wei Vivien Shi
Open Journal of Applied Biosensor (OJAB) , 2013, DOI: 10.4236/ojab.2013.22004
Abstract: This work proposes to design a fuzzy proportional-integral derivative (FPID) controller for dual-sensor cardiac pacemaker systems, which can automatically control the heart rate to accurately track a desired preset profile. The combination of fuzzy logic and conventional PID control approaches is adopted for the controller design based on dual-sensors. This controller offers good adaptation of the heart rate to the physiological needs of the patient under different states (rest and walk). Through comparing with the conventional fuzzy control algorithm, FPID provides a more suitable control strategy to determine a pacing rate in order to achieve a closer match between actual heart rate and a desired profile. To assist the heartbeat recovery, the stimuli with adjustable pacing rate is generated by the pacemaker according to the FPID controller, such actual heart rate may track the preset heart rate faithfully. Simulation results confirm that this proposed control design is effective for heartbeat recovery and maintenance. This study will be helpful not only for the analysis and treatment of bradycardias but also for improving the performance of medical devices.
Recent Advances of Sensors for Assistive Technologies  [PDF]
Wei (Vivien) Shi
Journal of Computer and Communications (JCC) , 2015, DOI: 10.4236/jcc.2015.35010
Abstract:

In this paper, the recent advances of sensors incorporated in assistive technologies are presented. Based on the function and operation of modern assistive devices, a variety of sensors are described with their features and applications. Further improvements and future trend are pointed out and discussed.

Sensors Applied in Healthcare Environments  [PDF]
Wei Vivien Shi
Journal of Computer and Communications (JCC) , 2016, DOI: 10.4236/jcc.2016.45015
Abstract:

In this paper, the recent advances of sensors applied in healthcare environments are presented. Based on the function and operation of modern health and wellness measurement and monitoring and mHealth solutions, a variety of sensors are described with their features and applications. Further improvements and future trend are pointed out and discussed.

Collapsing and Reconstructing of Building Language Reflection on Development and Actuality of the Traditional European Architecture in Qingdao City
Wei Shi
International Journal of Business and Management , 2009, DOI: 10.5539/ijbm.v3n5p90
Abstract: Buildings have their own ways of expressing themselves and this kind of expression needs to be put in a certain proper occasion. And this essay aims to find the way how to express a building more perfectly after master the modern construction technologies by reflecting on the Catholic churches and the nearby building blocks in Qingdao City.
Traceability in Acceptance Testing  [PDF]
Jean-Pierre Corriveau, Wei Shi
Journal of Software Engineering and Applications (JSEA) , 2013, DOI: 10.4236/jsea.2013.610A005
Abstract:

Regardless of which (model-centric or code-centric) development process is adopted, industrial software production ultimately and necessarily requires the delivery of an executable implementation. It is generally accepted that the quality of such an implementation is of utmost importance. Yet current verification techniques, including software testing, remain problematic. In this paper, we focus on acceptance testing, that is, on the validation of the actual behavior of the implementation under test against the requirements of stakeholder(s). This task must be as objective and automated as possible. Our first goal is to review existing code-based and model-based tools for testing in light of what such an objective and automated approach to acceptance testing entails. Our contention is that the difficulties we identify originate mainly in a lack of traceability between a testable model of the requirements of the stakeholder(s) and the test cases used to validate these requirements. We then investigate whether such traceability is addressed in other relevant specification-based approaches.

Is the Antiproteinuric Effect of Cyclosporine A Independent of Its Immunosuppressive Function in T Cells?
Bin Zhang,Wei Shi
International Journal of Nephrology , 2012, DOI: 10.1155/2012/809456
Abstract: The antiproteinuric effect of cyclosporine A(CsA) has been believed to result from its immunosuppressive effect on the transcription factor NFAT in T cells. However, current evidences supporting this hypothesis are missing. A recent study showed that CsA has a direct antiproteinuric effect on podocytes, suggesting a novel non-immunosuppressive mechanism for CsA's antiproteinuric effect. Conditional NFATc1 activation in podoyctes per se is sufficient to induce proteinuria in mice, indicating that NFAT activation in podocytes is a critical pathogenic molecular event leading to podocyte injury and proteinuria. Meanwhile, evidence showed that TRPC6-mediated Ca2+ influx stimulates NFAT-dependent TRPC6 expression. Altogether, these advances in podocyte research indicate that calcineurin-NFAT signal or calcineurin-synaptopodin axis has a direct proteinuric effect on podocytes which raises the possibility of developing specific antiproteinuric drugs that lack the unwanted effects of calcineurin or NFAT inhibition. 1. Introduction Clinically, calcineurin inhibitors (e.g., cyclosporine A, CsA) have been used to reduce proteinuria in focal segmental glomerulosclerosis (FSGS), minimal change disease (MCD), and other proteinuric kidney diseases [1]. T-cell dysfunction is associated with some forms of proteinuria, including a subset of MCD in children. This concept originally stemmed from the so called “Shalhoub hypothesis” that “lipoid nephrosis” is produced by a systemic abnormality of T-cell function [2]. For decades, FSGS was thought to be an immunologic disease resulting from the noxious effect of a lymphokine on the podocyte [3]. This was the primary reason for using CsA as an immunosuppressive drug, to continue to endorse this mechanism of action despite studies demonstrating that calcineurin inhibition reduced proteinuria in nonimmunologic glomerulopathies. Actually, CsA can also reduce proteinuria in human and experimental Alport’s syndrome, a nonimmunological disease, raising doubts of this hypothesis [4, 5]. Moreover, although CsA effectively lowered the level of proteinuria in human membranous nephropathy, the study of Ambalavanan et al. showed a more numerous and lager electron-dense immune deposits than before CsA’s therapy, indicating that whilst CsA exerts an antiproteinuric effect, the drug does not modify the histologic aggravation of the glomerular lesions [6]. A recent study showed that CsA has a direct antiproteinuric effect on podocytes [7].CsA blocked calcineurin-mediated dephosphorylation of the actin-organizing protein synaptopodin, a
Renal cell carcinoma metastasizing to solitary fibrous tumor of the pleura: a case report
Christopher Kragel, Shi Wei
Journal of Medical Case Reports , 2011, DOI: 10.1186/1752-1947-5-248
Abstract: A 58-year-old Caucasian man who developed a persistent dry cough presented to our hospital. Imaging studies revealed a large pleural-based mass in the left lung. A biopsy of the mass showed a spindle-cell lesion consistent with a solitary fibrous tumor. The patient underwent surgical excision of the 13 cm mass. The pathological examination confirmed the diagnosis of a solitary fibrous tumor but also demonstrated discrete foci of metastatic renal cell carcinoma. Until that point, a primary renal cell carcinoma tissue diagnosis had not been made and the initial radiological work-up was inconclusive.Awareness of the unusual phenomenon of tumor-to-tumor metastasis is important for practicing surgical pathologists, particularly in the evaluation of a mass lesion showing bimodal histology. This case also highlights the importance of careful examination of surgical specimens, as minute and unusual findings can direct patient care.The coexistence of two primary neoplasms in one patient is not uncommon, and these tumors may even arise at the same anatomic site ("collision tumor"). However, tumor-to-tumor metastasis is an extremely rare but interesting phenomenon. Since first described by Berent in 1902 [1], fewer than 200 cases have been reported in the English-language literature. The most frequent donor tumor site is the lung, while renal cell carcinoma is by far the most common recipient [2,3]. This combination constitutes approximately one-third of all reported cases. However, renal cell carcinoma acting as a donor tumor is extraordinarily rare, with only nine cases reported to date [4-12]. Interestingly, meningiomas are the most frequent recipients of donor renal cell carcinoma, followed by papillary carcinoma of the thyroid. Here we report the first case of a solitary fibrous tumor of the lung acting as the recipient of a donor renal cell carcinoma.A 58-year-old Caucasian man who developed a persistent dry cough and hemoptysis presented to our hospital. Computed tomogr
Privileged chiral catalysts in asymmetric Morita-Baylis-Hillman/aza-Morita-Baylis-Hillman reaction
Yin Wei,Min Shi
Chinese Science Bulletin , 2010, DOI: 10.1007/s11434-010-3119-2
Abstract: In the past decade, the asymmetric Morita-Baylis-Hillman (MBH)/aza-Morita-Baylis-Hillman (aza-MBH) reaction has attracted great attention because it leads to the formation of densely functionalized products in a catalytic and atom-economic way. The MBH/aza-MBH adducts can be further applied in a wide variety of organic synthesis, such as peptide synthesis and heterocyclic compounds synthesis. After a lot of attempts to improve the enantioselectivity, many types of chiral organocatalysts have been identified as highly enantioselective organocatalysts in MBH/aza-MBH reaction. Especially, certain “privileged chiral catalysts” are highly enantioselective in MBH/aza-MBH reaction, which are designed and developed through introducing bi-/multi-functional groups on the so-called “privileged structures” such as cinchona alkaloids, BINAP/BINOL. This review summarizes the exciting advances about the design and development of chiral catalysts derived from “privileged structures” and their applications in asymmetric MBH/aza-MBH reaction.
How to Cultivate the Ability of Innovative Thinking in Computer Programming Teaching
Fuqian Shi,Jincai Wei
International Education Studies , 2008, DOI: 10.5539/ies.v1n1p50
Abstract: In the current teaching activities on curriculum, teachers taught all kinds of computer language at the most of the time. Students also focus on a variety of examinations, but the real time to train students’ independent software developing skill is very limited. This has resulted in the students only to copy other people's systems design ideas, materials or other software reproduction procedures and take a simple so-called "Program Design." Based on this, this paper introduced a variety of computer teaching activities in classroom and formed role for training students’ imagination, the ability to find and explore, knowledge transfer capability and the quality of innovative thinking of students.
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