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Search Results: 1 - 10 of 153718 matches for " Wanis H. Ibrahim "
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Diagnostic Utility of Sago-Like Nodules on Gross Thoracoscopic Appearance in Tuberculous Pleural Effusion and Their Correlation with Final Histo-Microbiologic Findings  [PDF]
Merlin Thomas, Wanis H. Ibrahim, Tasleem Raza, Kamran Mushtaq, Adeel Arshad, Mushtaq Ahmed, Salma Taha, Shireen Omer, Saber Al Sarafandi, Omer Rabadi, Hisham A. Abdul-Sattar
Journal of Tuberculosis Research (JTR) , 2018, DOI: 10.4236/jtr.2018.64024
Abstract: Background: Distinguishing tuberculous pleural effusion (TPE) from other causes of exudative effusion is often challenging. Delay in treatment initiation can occur while awaiting histo-microbiologic confirmation owing to the paucibacillary nature of the disease. Sago-like nodules are the most common visual finding on gross thoracoscopic appearance. The primary objective was to determine the diagnostic utility of the presence of sago-like nodules on gross thoracoscopic appearance in TPE to help justify early initiation of tuberculosis (TB) treatment based on their finding while awaiting final histo-microbiologic confirmation. Secondary objective was to study the correlation between the presence of sago-like nodules and the final histo-microbiologic findings in pleural biopsy specimens. Methods: This was a retrospective-descriptive study of all patients with exudative pleural effusion who underwent diagnostic medical thoracoscopy (MT) at Hamad General Hospital during an eight-year period (from January, 2008 to December, 2015). Results: The presence of sago-like nodules on gross thoracoscopic appearance of the pleural surface had a sensitivity of 58%, a specificity of 89% and a positive predictive value of 97% for TPE with a diagnostic accuracy of 62%. There is significant association between the presence of sago-like nodules and demonstration of granulomatous inflammation in pleural biopsy specimens (P = 0.000). There is no association between sago-like nodules and positive TB smear and culture in biopsy specimens. Conclusion: The presence of sago-like nodules on gross thoracoscopic appearance has a high specificity and positive predictive value for TPE and significantly correlates with the presence of granulomatous inflammation. Patients from TB prevalent areas with exudative pleural effusion and sago-like nodules on gross thoracoscopic appearance may be commenced on TB chemotherapy while awaiting final histologic confirmation.
Diagnostic Delay and Associated Clinical Features of Tuberculosis among Adult Patients with Acute Myeloid Leukemia in Doha, Qatar  [PDF]
Halima El Omri, Ruba Taha, Wanis Ibrahim, Nancy Kassem, Lajos Szabados, Hesham El Sabah, Fatma Ben Abid, Amna Gamiel, Aisha Al Khinji, Wojciech Szmeigielski, Saba Hasan, Ibrahim Al Hijji
Journal of Tuberculosis Research (JTR) , 2018, DOI: 10.4236/jtr.2018.61005
Abstract: Background: Tuberculosis is currently the world’s leading cause of death arising from a single infectious condition. While T cell mediated immunity is recognized to have a major contribution to tuberculosis activation, the present investigation confirmed that TB was more prevalent among patients with acute myeloid rather than lymphoid leukemia and such association was frequently overlooked. The primary objective of this study is to estimate the diagnostic delay of tuberculosis among patients with acute myeloid leukemia (AML) and compare it to the general population in Qatar. Secondary objective is to study the clinical and epidemiologic characteristics of tuberculosis in patients with AML. Methods: This is a retrospective study of tuberculosis cases diagnosed in subjects with AML during the period from January 2008 till December 2016. Results: Among 215 subjects with AML identified during the study period, 12 (5.58%) received the diagnosis of tuberculosis. The estimated incidence of tuberculosis among AML cases was 7.14 cases per 1000 per year. The mean delay in diagnosis of tuberculosis was 64.2 days (95% CI: 26.8 - 101.5) and the median was 45 days (interquartile range; Q1 - Q3, 29.5 - 97.5). Prolonged fever was the most common presentation (100% of cases). Parenchymal lung involvement was the most common radiologic abnormality (83.3% of cases). Three patients (25%) died and 8 patients completed 9 to 12 months of anti-tuberculous treatment with clinical and radiological remission. Conclusion: Infections caused by Mycobacterium tuberculosis are not uncommon in patients with AML especially in patients from tuberculosis endemic regions. It constitutes a diagnostic challenge so high index of suspicion is of paramount importance.
A Roadmap for Reconfiguring Industrial Enterprises as a Consequence of Global Economic Crisis (GEC)  [PDF]
Ibrahim H. Garbie
Journal of Service Science and Management (JSSM) , 2010, DOI: 10.4236/jssm.2010.34048
Abstract: Due to the existing depression, industrial enterprises in most of the world require to be reconfigured and/or reorganized especially the manufacturing firms (companies). As a consequence of the global economic crisis (GEC), great political and economical maybe changed and some companies will go out from business and others will be merged with other firms. Also, a big effecting will be represented in unemployment. The industrial enterprises will start to deal intensively for better utilization of resources (e.g., equipments, machines, etc.) and human resources. There are a lot of issues needed to be addressed to cope with this recession. The most important issue is then the opportunity to learn new skills and techniques. The other issues which this paper illustrated representing in complexity level of industrial enterprises, designing hybrid or innovative manufacturing systems, applied manufacturing strategies and philosophies, product development, management for change, and good accounting system. In this paper, a conceptual framework as a roadmap for discussing these issues of reconfiguring industrial enterprises will be explained and discussed. The analysis shows that reconfiguring industrial enterprises is not easy task and a multi-dimensional problem.
Anodic Stripping Voltammetric Determination of Nitrite Using Carbon Paste Electrode Modified with Chitosan  [PDF]
Ibrahim H. I. Habib
American Journal of Analytical Chemistry (AJAC) , 2011, DOI: 10.4236/ajac.2011.22035
Abstract: A simple method for anodic stripping voltammetric determination of nitrite using carbon paste electrode modified with biomolecular chitosan, is described. In this method, the electrode is activated electrochemically by scanning 5 replicates over the potential range from +500 to +1400 mV immersing in 0.5 M HCl solution. Following this step, the nitrite sample containing 0.1 M KCl is preconcentrated on the activated electrode at +500 mV for 30 s. The deposited anions are then oxidized by different modes of sweep in the oxidation direction. Chemical and electrical parameters affecting the voltammetric measurements are optimized. The peak current is linear proportional to the NO2- concentration within the range 0.41 - 4.1 µg/ml, with detection limit 0.187 µg/m using differential pulse mode. The relative standard deviation is 0.285% for 2.46 µg/ml (five replicates). No interference is observed due to oxygen dissolved in the sample so that nitrogen purging is not needed in this case. The result obtained by the modified electrode is more accurate and selective than the unmodified electrode.
Converting Traditional Production Systems to Focused Cells as a Requirement of Global Manufacturing  [PDF]
Ibrahim H. Garbie
Journal of Service Science and Management (JSSM) , 2011, DOI: 10.4236/jssm.2011.43032
Abstract: The converting process from traditional production systems (e.g., Job Shops) to focused (cellular) systems is important as one requirement of global manufacturing to challenge the existing global financial crisis. This represents a big problem and a huge task for manufacturers and academicians which almost most of industrial enterprises around the world are still working as a job shop. This converting process means breaking or dividing the existing functional (process) layout into independently and distinctly focused manufacturing cells to gain on the conversion benefits. To consider this issue, a new methodology of converting job shops into cellular systems is introduced based on the requirements of global manufacturing regarding manufacturing systems design only. These requirements are: responsiveness, reconfigurable machines, mass customization, innovative and manufacturing systems configuration. A complete industrial case study will be used to analyze and explain the proposed methodology in a small-sized job shop manufacturing firm.
Pharmacist Role in Pharmaceutical Care during Ramadan  [PDF]
Osama H. Mohamed Ibrahim
Pharmacology & Pharmacy (PP) , 2015, DOI: 10.4236/pp.2015.612061
Abstract: Introduction: Ramadan is the ninth month in the Islamic Hijri calendar where Muslims are ex-pected to fast every day from dawn to sunset. The eating behavior changes during Ramadan and the abstinence of food affects the oral drugs administration and other convenience dosage forms. There is a need to highlight and illustrate the role of the pharmacists in medication adjustment challenges that the patients conquer in the Holy month of Ramadan. Objectives: To estimate the awareness of pharmacists’ role in providing pharmaceutical care during Ramadan; moreover, to explore pharmacists’ perspective on the importance of medication regimen adjustment along with the proper counseling required to optimize patients’ health throughout fasting. Method: This is an observational study that was done through dissemination of a cross-sectional survey among 130 pharmacists covering Abu Dhabi, Dubai, Sharjah, Ajman, and Northern Emirates regions. The targeted population consisted of practicing community pharmacists and hospital pharmacists across UAE. Results: Among pharmacists participated in the study 115 pharmacists (88.5%) were Muslims and 79 pharmacists (60.8%) were Arabs. 126 pharmacists (97%) reported performing one or more kinds of medication regimen adjustment around Ramadan for at least one patient. Changing the frequency had the highest percentage by the pharmacist compared to other methods of regimen adjustment (39%). Moreover, the results revealed that 46.9% of the pharmacists chose not to change the medication itself. Nineteen percent of Muslim pharmacists initiated the conversation about medication regimen adjustment (P = 0.0448) compared to non-Muslims, while14% of pharmacists were Arabs who showed no statistically significant difference. Conclusion: In conclusion, pharmacists are more qualified to adjust and manage medication regimens than what they are presently performing. Utilization of such skill is required to adjust patients’ medication regimen during fasting the Holy month of Ramadan and to ensure safe transition for fasting patients into and out of Ramadan.
Preoperative Versus Postoperative Radiation Therapy in Patients with Soft Tissue Sarcomas
Mohamed Ibrahim El-sayed,Doaa Wadie Maximos,Mostafa El-sayed Abdel-wanis,Amen Hamdy Zaky
Cancer and Clinical Oncology , 2012, DOI: 10.5539/cco.v1n2p36
Abstract: Purpose: To evaluate treatment outcome and to determine whether or not the timing of radiotherapy (RT) was associated with any difference in disease relapse, survival, or incidence of complications in patients with soft tissue sarcomas (STS). Methods: The medical files of 63 patients with a primary, nonmetastatic, STS, treated with surgery and irradiation were evaluated. Data regarding tumor stage, grade, site, dosage and timing of radiotherapy, treatment complications, disease relapse, and disease-free (DFS) and overall survival (OAS) rates were analyzed. Results: The median follow up was 47 months (range; 5-66 months). Four-year OAS and DFS rates were 82.6% and 78.8% respectively. There were significant higher 4-year OAS (p = 0.024) and DFS (p = 0.011) rates in patients with stage I and II diseases than those in patients with stage III disease. On the other hand, there were no significant differences in 4-year OAS (p = 0.83, HR: 0.743, 95% CI: 0.165 to 3.345) and DFS (p = 0.64, HR: 0.74, 95% CI: 0.21 to 2.61) rates between preoperative and postoperative RT patients. Disease relapse for preoperative versus postoperative RT patients was not statistically different (p = 0.41). Wound complications were more frequent in preoperative RT patients (25%) compared to postoperative RT patients (8%) (p = 0.0566 chi-square). Conclusions: Preoperative irradiation has not a positive impact on survival or disease relapse rates, but is associated with high wound complication rate.
Structural Deformation Monitoring and Analysis of Highway Bridge Using Accurate Geodetic Techniques  [PDF]
Ashraf Abd El-Wanis Beshr
Engineering (ENG) , 2015, DOI: 10.4236/eng.2015.78045
Abstract: As the new materials and technologies are increasingly applied to construction of civil infrastructures such bridges, dam and tunnels, the need for structural monitoring systems, maintenance and restoration becomes more important and vital. Bridges are widespread in every society and affect its human, social, economical and cultural aspects. Measurements and monitoring of the structural deformation of highway bridges have an essential role in structural safety. This paper investigates an integrated monitoring system for estimation of the deformation behavior of one of the important reinforced bridges in Egypt. The applied data for analysing the deformation of any structure from geodetic observations are the coordinates of several monitoring points distributed on the structure itself. The coordinates of these points are calculated with respect to control fixed points. So any deviations in the control points coordinates between the two successive epochs of observations will affect the values of structural deformation. To overcome this shortage, applying the multi-parameter transformation will be studied in this paper for structural health monitoring of bridges. Statistical tests using F-Fisher criterion with a confidence level of 98% of the geodetic observations for bridge deformation values are also presented. The results of the practical measurements, analysis of the interesting deformation technique and traffic flow around the studied highway bridge are also presented. The resulting structural deformation values from statistical tests provide a significant improvement of understanding and prediction the structure deformation values of highway bridges.
A Generalization of a Logarithmic Sobolev Inequality to the H?lder Class
H. Ibrahim
Journal of Function Spaces and Applications , 2012, DOI: 10.1155/2012/148706
Abstract: In a recent work of the author, a parabolic extension of the elliptic Ogawa type inequality has been established. This inequality is originated from the Brézis-Gallouët-Wainger logarithmic type inequalities revealing Sobolev embeddings in the critical case. In this paper, we improve the parabolic version of Ogawa inequality by allowing it to cover not only the class of functions from Sobolev spaces, but also the wider class of Hölder continuous functions.
Voltage profile generation for simultaneous multi-protein detection in western blot analysis  [PDF]
Matthew Blair, Mina Wanis, Gaurav Swarnkar, Hiroki Yokota, Stanley Chien
Journal of Biomedical Science and Engineering (JBiSE) , 2012, DOI: 10.4236/jbise.2012.59067
Abstract: Western blotting is a popular technique for examining expression levels of proteins using gel-based electrophoretic fractionation followed by blotting and antibody reactions. Although this is a mature technique, one of the major limitations is the need to prepare an individual electrophoretic gel for each of the protein species to be analyzed. Since most analyses require the detection of multiple protein species, a procedure that allows utilization of a single gel for detecting multiple protein species should significantly save time and resources. In this paper, we developed a novel multiprotein detection device, which enabled simultaneous detection of several proteins species from a single electrophoretic gel. In this device, a protein transfer unit utilized a multi-anode plate that generated a non-uniform voltage profile. This voltage profile enabled uniform transfer regardless of molecular mass of proteins. In vitro experiments using samples, isolated from boneforming osteoblast cells, showed that the expression levels of 5 - 7 different proteins were detectable in the presence and absence of mechanical stimulation that activated genes necessary for bone formation. The result supports the notion that through simultaneous detection of multiple protein species, the described device contributes to reduction in procedural time and sample amounts, as well as a removal of variations among multiple gels.
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