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Search Results: 1 - 10 of 180645 matches for " Walkyria de Paula;Pontes "
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A importancia do teste de tolerancia à glicose oral no diagnóstico da intolerancia à glicose e diabetes mellitus do tipo 2 em mulheres com síndrome dos ovários policísticos
Pontes, Ana Gabriela;Rehme, Marta Francis Benevides;Micussi, Maria Thereza Albuquerque Barbosa Cabral;Maranh?o, Técia Maria de Oliveira;Pimenta, Walkyria de Paula;Carvalho, Lídia Raquel de;Pontes, Anaglória;
Revista Brasileira de Ginecologia e Obstetrícia , 2012, DOI: 10.1590/S0100-72032012000300007
Abstract: purpose: to evaluate the importance of the oral glucose tolerance test for the diagnosis of glucose intolerance (gi) and type 2 diabetes mellitus (dm-2) in women with pcos. methods: a retrospective study was conducted on 247 patients with pcos selected at random. the diagnosis of gi was obtained from the two-hour oral glucose tolerance test with 75 g of glucose according to the criteria of the world health organization (who) (gi: 120 minutes for plasma glucose >140 mg/dl and <200 mg/dl), and the diagnosis of dm-2 was obtained by both the oral glucose tolerance test (dm: 120 minutes for plasma glucose >200 mg/dl) and fasting glucose using the criteria of the american diabetes association (impaired fasting glucose: fasting plasma glucose >100 and <126 mg/dl; dm: fasting glucose >126 mg/dl). a logistic regression model for repeated measures was applied to compare the oral glucose tolerance test with fasting plasma glucose. anova followed by the tukey test was used for the analysis of the clinical and biochemical characteristics of patients with and without gi and/or dm-2. a p<0.05 was considered statistically significant. results: pcos patients had a mean age of 24.8±6.3, and body mass index (bmi) of 18.3 to 54.9 kg/m2 (32.5±7.6). the percentage of obese patients was 64%, the percentage of overweight patients was 18.6% and 17.4% had healthy weight. the oral glucose tolerance test identified 14 cases of dm-2 (5.7%), while fasting glucose detected only three cases (1.2%), and the frequency of these disorders was higher with increasing age and bmi. conclusions: the results of this study demonstrate the superiority of the oral glucose tolerance test in relation to fasting glucose in diagnosing dm-2 in young women with pcos and should be performed in these patients.
Resistência à insulina em mulheres com síndrome dos ovários policísticos: rela??o com as variáveis antropométricas e bioquímicas
Pontes, Ana Gabriela;Rehme, Marta Francis Benevides;Martins, Anice Maria Vieira de Camargo;Micussi, Maria Thereza Albuquerque Barbosa Cabral;Maranh?o, Técia Maria de Oliveira;Pimenta, Walkyria de Paula;Pontes, Anaglória;
Revista Brasileira de Ginecologia e Obstetrícia , 2012, DOI: 10.1590/S0100-72032012000200006
Abstract: purpose: to analyze the prevalence of insulin resistance, according to different biochemical and anthropometric measurements in women with polycystic ovary syndrome. methods: a total of 189 patients with polycystic ovary syndrome were retrospectively analyzed. insulin resistance diagnosis was performed using fasting insulin, homa-ir, quicki, insulin sensibility index and glucose/fasting insulin ratio. body mass index and lipid accumulation product were used. data were analyzed statistically by descriptive statistics, anova, tukey post-test, and pearson's correlation. results: the polycystic ovary syndrome patients had a mean age of 24.9±5.2 and a mean body mass index of 31.8±7.6. the percentage of obese patients was 57.14%. among the methods of insulin resistance investigation, the insulin sensibility index was the technique that most detected (56.4%) the presence of insulin resistance in women with polycystic ovary syndrome. the insulin resistance was detected in 87% of obese patients. the fasting glucose/fasting insulin ratio and insulin sensibility index were strongly correlated with lipid accumulation product. conclusion: the prevalence of insulin resistance varied according to the method used, and it was greater the higher the body mass index. lipid accumulation product was also related to insulin resistance.
A ultra-sonografia do pancreas é eficaz em diagnosticar o diabete melito tipo 1 e tipo 2?
Pimenta Walkyria de Paula,Teixeira Altamir Santos,Aragon Flávio Ferrari,Baptistelli Elda Eveline
Radiologia Brasileira , 2002,
Abstract: Este trabalho foi realizado para verificar se a ultra-sonografia do pancreas oferece dados auxiliares na classifica o de diabéticos adultos dos tipos 1 e 2. O tamanho e a ecogenicidade do pancreas foram determinados pela ultra-sonografia em 81 diabéticos, sendo 20 do tipo 1 e 61 do tipo 2 (53 obesos e oito n o-obesos). Os pacientes tipo 2 obesos diferiram dos demais por apresentarem área total e diametro antero-posterior do corpo do pancreas significativamente maiores. Quanto à ecogenicidade pancreática, esta estava aumentada com maior freqüência nos diabéticos tipo 2 obesos que nos diabéticos tipo 1. Consideramos, assim, que a ultra-sonografia do pancreas constitui metodologia auxiliar na classifica o de diabéticos entre os tipo 1 e 2, sendo menos eficaz quando os últimos n o s o obesos.
Sobrepeso na adolescência de filhos de m?es que tiveram distúrbios glicêmicos na gesta??o
Buzinaro, Elizabeth Fernandes;Berchieri, Carolina Bragiola;Haddad, Adriana Lúcia Mendes;Padovani, Carlos Roberto;Pimenta, Walkyria de Paula;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2008, DOI: 10.1590/S0004-27302008000100012
Abstract: aim: to verify whether different hyperglycemia levels during pregnancy cause frequency differences in adolescent obesity and its morbidities in the offspring. methods: seventy-three children were divided into three groups according to maternal glucose tolerance: g1 (n=27) normal oral glucose tolerance test (ogtt) and daily glycemia (dg); g2 (n=23) normal ogtt and high dg; g3 (n=23) abnormal ogtt and dg (gestational diabetes mellitus; gdm). all underwent clinical evaluation (anthropometry) a questionnaire(neonatal data, eating habits), and determination of fasting serum glucose and lipid profile measurement. analysis of variance (anova) and the goodman?s test were used to compare the groups. results: g3 mothers showed higher fasting plasma glucose(fpg) and dg than g2 and g1(fpg: 93±10 vs 83±5 vs 78±10mg/dl; dg: 104±12 vs 93±7 vs 85±9mg/dl, respectively; p<0.001). g2 mothers had higher dg than g1 (93±7 vs 85±9mg/dl; p<0.001). g3 offspring birthweight was higher than g1 and g2 (3,667±527 vs 3,167±565 and 3,282±401g, respectively; p<0.05). more g3 offspring were overweight than g1 (52.2 vs 14.8%; p<0.05). conclusions: offspring of gdm mothers with fasting and daily hyperglycemia have higher birthweight and overweight frequency in adolescence. these children must be followed up from infancy.
Avalia??o quanto à presen?a de microalbuminúria e hiperfiltra??o glomerular no estágio de tolerancia à glicose diminuída
Cruz, Ney de Souza;Sartori, Maria Salete;Santos, Maria Luiza dos;Aragon, Flávio Ferrari;Padovani, Carlos Roberto;Pimenta, Walkyria de Paula;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2003, DOI: 10.1590/S0004-27302003000200008
Abstract: in the impaired glucose tolerance (igt) phase, there are already several characteristic metabolic abnormalities and risk factors in type 2 diabetes mellitus, which predispose them to develop vasculopathy. we looked for increased urinary albumin excretion (uae) and creatinine clearance (ccr) in brazilians with igt and normal blood pressure. the standard oral glucose tolerance test with plasma insulin was performed to classify participants into two groups: igt and normal glucose tolerance (ngt). overnight urine collection was used to assess the uae (immunoturbidimetry) and ccr. no differences were observed between the groups in regarding uae and ccr. the frequency of microalbuminuria was 21.1 and 3.3% for the igt and ngt groups, respectively (ns). in conclusion, brazilians with igt, normal blood pressure and insulin resistance did not present microalbuminuria or glomerular hyperfiltration.
A ultra-sonografia do pancreas é eficaz em diagnosticar o diabete melito tipo 1 e tipo 2?
Pimenta, Walkyria de Paula;Teixeira, Altamir Santos;Aragon, Flávio Ferrari;Baptistelli, Elda Eveline;Moreira, Adriana Guanaes;Castro, Ana Valéria Barros de;Padovani, Carlos Roberto;
Radiologia Brasileira , 2002, DOI: 10.1590/S0100-39842002000400006
Abstract: the aim of this study was to determine whether ultrasonography of the pancreas can be used as an auxiliary tool in the diagnosis of adult patients with type 1 and type 2 diabetes mellitus. the size and echogenicity of the pancreas were evaluated by ultrasound in 81 diabetic patients: 20 type 1 and 61 type 2 (53 obese and 8 non-obese). obese type 2 diabetic patients showed different results from patients in the other groups, with significantly larger pancreas area and anteroposterior body diameter. the pancreas was more frequently hyperechogenic in obese type 2 diabetic patients than in type 1 diabetic patients. we concluded that ultrasonography of the pancreas may be used as an auxiliary tool for the diagnosis of type 1 and type 2 diabetic patients, although this method showed to be less efficient in non-obese patients.
Ocorrência de diabetes melito em mulheres com hiperglicemia em gesta??o prévia
Silva,Márcia Rocha Gabaldi; Calderon,Iracema de Mattos Paranhos; Gon?alves,Luciana Colnago; Aragon,Flávio Ferrari; Padovani,Carlos Roberto; Pimenta,Walkyria de Paula;
Revista de Saúde Pública , 2003, DOI: 10.1590/S0034-89102003000300013
Abstract: objective: to estimate the prevalence of glucose intolerance (diabetes mellitus and impaired glucose tolerance) in women who had their glucose tolerance evaluated and followed up during pregnancy. methods: over the last 12 years since the index pregnancy, from a total of 3,113 pregnant women seen in an obstetrics clinic, 551 were randomly selected and proportionally to the number of women in each group. of these, 529 could be evaluated and had been classified as follows: 250 in group ia (normal glucose tolerance); 120 in group ib (daily hyperglycemia); 72 in group iia (abnormal oral glucose tolerance test); and 87 in group iib (abnormal oral glucose tolerance test and daily hyperglycemia). the evaluation consisted of measuring fasting plasma glucose and when the results ranged between 6.1 and 6.9 mmol/l, patients were submitted to oral glucose tolerance test. results: prevalence of diabetes mellitus was: ia, 1.6%; ib, 16.7%; iia, 23.6%; and iib, 44.8% (ia < [ib=iia]
Pyroelectric composite film for X-ray intensity detection
Sakamoto, Walter Katsumi;Estevam, Giuliano Pierre;Carvalho, Aparecido Augusto de;Pontes, Wesley;Paula, Mauro Henrique de;
Materials Research , 2012, DOI: 10.1590/S1516-14392012005000030
Abstract: composite material obtained with modified lead titanate (pz34) ferroelectric ceramic and polyether-ether-ketone (peek) polymer matrix was used as sensitive component to measure x-ray intensity in a novel detection system. the sensing element works as a thermal transducer, converting a non-quantified thermal flux into an output measurable quantity of electrical voltage. the samples were obtained up to 60 vol.% of ceramic, by hot pressing the mixture of pz34 and peek powders at 368 °c and applying 12 mpa pressure for 2.0 hours. the sensor response varies from 2.70 to 0.80 v in the energy fluence rate range of 6.30 to 37.20 w.m-2. the absorbed incident energy was analyzed as a function of the ionizing energy. furthermore, by measuring the pyroelectric activity of the composite film it was observed that there is no degradation of the sensor after the irradiation.
Evolu??o de variáveis hemodinamicas e perfusionais durante o choque séptico experimental tratado com ressuscita??o volêmica guiada por metas
Park, Marcelo;Rosário, André Loureiro;Schettino, Guilherme de Paula Pinto;Azevedo, Luciano César Pontes;
Revista Brasileira de Terapia Intensiva , 2011, DOI: 10.1590/S0103-507X2011000300005
Abstract: objectives: although fluid resuscitation guided by central venous oxygen saturation (svco2) is currently considered the gold standard in sepsis therapy, few studies have described hemodynamic and perfusion parameters during this procedure. this study aims to describe these parameters during septic shock without resuscitation and after 12 hours of goal-directed resuscitation. methods: thirteen anesthetized pigs (35-45 kg) had peritonitis caused by fecal inoculation (0.75 g/kg). after developing persistent hypotension, both groups were given antibiotics and randomized either to the control group (n=7) or the experimental group (n=6). in the control group, hemodynamic control was optimized to maintain a central venous pressure of 8-12 mmhg, a urinary output above 0.5 ml/kg/hour and a mean arterial blood pressure above 65 mmhg. the experimental group received the above target therapy in addition to maintaining a svo2 above 65%. the interventions included lactated ringer's solution and norepinephrine for both groups and dobutamine in the svo2 group. the animals were treated for 12 hours or until death. results: untreated sepsis was associated with significant reductions in svo2, pvo2, cardiac output and central venous pressure in addition to increased arteriovenous oxygen saturation and veno-arterial co2 differences. following resuscitation, these parameters were corrected in both groups. goal-directed resuscitation was associated with a better hemodynamic profile, characterized by higher svo2, cardiac output and central venous pressure. conclusions: non-resuscitated sepsis showed a hemodynamic profile suggesting hypovolemia, with worsened perfusion and hemodynamics, which is reversed upon fluid resuscitation. goal-directed resuscitation is associated with significantly improved hemodynamic and perfusion parameters
Leukemia mortality trends among children, adolescents, and young adults in Latin America
Curado,Maria Paula; Pontes,Thais; Guerra-Yi,Marta E.; Cancela,Marianna de Camargo;
Revista Panamericana de Salud Pública , 2011, DOI: 10.1590/S1020-49892011000200004
Abstract: objective: to describe and compare trends in leukemia mortality among children (0-14 years of age) and adolescents and young adults (aya, 15-24 years of age) in 12 countries in latin america during 1980-2004. methods: data from the world health organization mortality database was analyzed using a joinpoint regression model to identify significant mortality rate changes over time and to estimate annual percent change. results: leukemia is ranked first among cancer-related causes of death among children and aya in latin america. in children, the global percentage changes indicate increased rates for both sexes in colombia, ecuador, and mexico, with substantially higher rates for mexico. in aya, significant increases were observed for both sexes in mexico; ecuador saw some increase for both sexes; and colombia and uruguay had increases in females only. downward trends were observed in argentina for both sexes, and in costa rica for males only. there were no major changes in the other countries analyzed. conclusions: leukemia mortality rates among aya are declining, but show less significant decreases than rates among children. the study results point to a global need for further advances, specifically for aya, similar to those made by childhood leukemia therapeutic protocols. also, specialized oncological centers exist in most countries of latin america, but they are often inaccessible. special attention should be given to mexico due to the significant increase in mortality rates.
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