oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

4 ( 1 )

2019 ( 229 )

2018 ( 472 )

2017 ( 447 )

Custom range...

Search Results: 1 - 10 of 291069 matches for " Wagner R. da;Souza "
All listed articles are free for downloading (OA Articles)
Page 1 /291069
Display every page Item
Operant measurement of auditory threshold in prelingually deaf users of cochlear implants: II
Silva, Wagner R. da;Souza, Deisy G. de;Bevilacqua, Maria Cecília;Lopes Jr., Jair;
Psychology & Neuroscience , 2011, DOI: 10.3922/j.psns.2011.1.011
Abstract: two experiments evaluated an operant procedure for establishing stimulus control using auditory and electrical stimuli as a baseline for measuring the electrical current threshold of electrodes implanted in the cochlea. twenty-one prelingually deaf children, users of cochlear implants, learned a go/no go auditory discrimination task (i.e., pressing a button in the presence of the stimulus but not in its absence). when the simple discrimination baseline became stable, the electrical current was manipulated in descending and ascending series according to an adapted staircase method. thresholds were determined for three electrodes, one in each location in the cochlea (basal, medial, and apical). stimulus control was maintained within a certain range of decreasing electrical current but was eventually disrupted. increasing the current recovered stimulus control, thus allowing the determination of a range of electrical currents that could be defined as the threshold. the present study demonstrated the feasibility of the operant procedure combined with a psychophysical method for threshold assessment, thus contributing to the routine fitting and maintenance of cochlear implants within the limitations of a hospital setting.
Operant measurement of auditory threshold in prelingually deaf users of cochlear implants: II
Wagner R. da Silva,Deisy G. de Souza,Maria Cecília Bevilacqua,Jair Lopes Jr.
Psychology & Neuroscience , 2011,
Abstract: Two experiments evaluated an operant procedure for establishing stimulus control using auditory and electrical stimuli as a baseline for measuring the electrical current threshold of electrodes implanted in the cochlea. Twenty-one prelingually deaf children, users of cochlear implants, learned a Go/No Go auditory discrimination task (i.e., pressing a button in the presence of the stimulus but not in its absence). When the simple discrimination baseline became stable, the electrical current was manipulated in descending and ascending series according to an adapted staircase method. Thresholds were determined for three electrodes, one in each location in the cochlea (basal, medial, and apical). Stimulus control was maintained within a certain range of decreasing electrical current but was eventually disrupted. Increasing the current recovered stimulus control, thus allowing the determination of a range of electrical currents that could be defned as the threshold. The present study demonstrated the feasibility of the operant procedure combined with a psychophysical method for threshold assessment, thus contributing to the routine ftting and maintenance of cochlear implants within the limitations of a hospital setting.
Medidas operantes de limiar auditivo em crian?as com surdez pré-lingual, usuárias de implante coclear
Silva, Wagner R. da;Souza, Deisy das Gra?as de;Bevilacqua, Maria Cecília;Kimura, Márcia Y. T.;Lopes Jr., Jair;
Psicologia: Reflex?o e Crítica , 2011, DOI: 10.1590/S0102-79722011000200018
Abstract: auditory thresholds of prelingually deaf children who received cochlear implants were evaluated for the electrical stimulation to one of the medial electrodes. a go/no go operant procedure was used to teach a simple discrimination, indicated by a motor response, between the presence versus the absence of an auditory stimulus. simple discrimination was used as a baseline upon which the electrical stimulus's intensity was manipulated in a decreasing sequence followed by an increasing sequence, according to a modified psychophysical staircase method. the accuracy of responding in the presence of the electrical stimulus was reduced for all seven participants when the stimulus intensity decreased bellow a certain value and was recovered when the stimulus intensity was increased to the previous level. the experimental design allowed reliable identification of individual thresholds. the results suggest that the psychophysical paradigm in combination with the operant procedure might be useful for the evaluation of the auditory threshold for purposes of cochlear implant fitting in clinical settings.
Chronic administration of Abarema cochliacarpos attenuates colonic inflammation in rats
Silva, Maria Silene da;Sánchez-Fidalgo, Susana;Cárdeno, Ana;Talero, Elena;Silva, Marcelo Aparecido da;Vilegas, Wagner;Brito, Alba R. M. Souza;Lastra, Catalina A. de la;
Revista Brasileira de Farmacognosia , 2011, DOI: 10.1590/S0102-695X2011005000122
Abstract: inflammatory bowel diseases are characterized by a chronic clinical course of relapse and remission associated with self-destructive inflammation of the gastrointestinal tract. active extracts from plants have emerged as natural potential candidates for its treatment. abarema cochliacarpos (gomes) barneby & grimes, fabaceae (barbatim?o), is a native medicinal plant in to brazil. previously we have demonstrated in an acute colitis model a marked protective effect of a butanolic extract, so we decided to assess its anti-inflammatory effect in a chronic ulcerative colitis model induced by trinitrobenzensulfonic acid (tnbs). abarema cochliacarpos (150 mg/day, v.o.) was administered for fourteen consecutive days. this treatment decreased significantly macroscopic damage as compared with tnbs. histological analysis showed that the extract improved the microscopic structure. myeloperoxidase activity (mpo) was significantly decreased. study of cytokines showed that tnf-α was diminished and il-10 level was increased after abarema cochliacarpos treatment. in order to elucidate inflammatory mechanisms, expression of cyclooxygenase (cox)-2 and nitric oxide synthase (inos) were studied showing a significant downregulation. in addition, there was reduction in the jnk and p-38 activation. finally, iκb degradation was blocked by abarema cochliacarpos treatment being consistent with an up-regulation of the nf-kappab-binding activity. these results reinforce the anti-inflammatory effects described previously suggesting that abarema cochliacarpos could provide a source for the search for new anti-inflammatory compounds useful in ulcerative colitis treatment.
Improving Cry8Ka toxin activity towards the cotton boll weevil (Anthonomus grandis)
Gustavo R Oliveira, Maria CM Silva, Wagner A Lucena, Erich YT Nakasu, Alexandre AP Firmino, Magda A Beneventi, Djair SL Souza, José E Gomes, José DA de Souza, Daniel J Rigden, Hudson B Ramos, Carlos R Soccol, Maria F Grossi-de-Sa
BMC Biotechnology , 2011, DOI: 10.1186/1472-6750-11-85
Abstract: Bioassays carried out with A. grandis larvae revealed that the LC50 of the screened mutant Cry8Ka5 toxin was 3.15-fold higher than the wild-type Cry8Ka1 toxin. Homology modelling of Cry8Ka1 and the Cry8Ka5 mutant suggested that both proteins retained the typical three-domain Cry family structure. The mutated residues were located mostly in loops and appeared unlikely to interfere with molecular stability.The improved toxicity of the Cry8Ka5 mutant obtained in this study will allow the generation of a transgenic cotton event with improved potential to control A. grandis.Anthonomus grandis (Coleoptera: Curculionidae), commonly known as the cotton boll weevil, is the most harmful cotton-feeding insect-pest in the Americas [1-4]. Even in cotton fields where the insect has been considered eradicated (e.g. Mississipi State USA), the growers must maintain a continued vigil because of the tremendous ability of the boll weevil to return to previous controlled regions from time to time to re-infest. Millions of dollars in insecticides were spent by growers to have areas eradicated. In not eradicated areas, yield losses to boll weevil exceeded until 10 percent in certain years and the growers had to apply 8-12 boll weevil sprays per field [5]. These repeated treatments are necessary, because only adult boll weevils feed on tender cotton terminals, on pollen from flower buds and on fruits. The larvae are protected inside the boll, which makes difficult the contact with chemical pesticides. Recently presented during forum Brazil' 2010/11, cotton area production is estimated at 1.2 million of hectares the highest since the early 1990's [6]. However, especially in Brazil, boll weevil is considered a key pest in cotton fields and despite of pest management and several insecticide sprays, an efficient boll weevil control does not exist. As an alternative to chemicals, the use of transgenic plants resistant to A. grandis presents a potential solution to the problem posed by insect-pe
Alternating hemiplegia of childhood: Case report
Abram Topczewski,Jairo Wagner,Patricia da Silva Souza
Einstein (S?o Paulo) , 2006,
Abstract: The case of a 13-year old boy presenting alternating hemiplegia ofchildhood that began later than usual is reported. The clinical coursesuggests, however, a case of benign alternating hemiplegia ofchildhood. The treatment with flunarizine was good for the patient.
Sustained Reduction of the Dengue Vector Population Resulting from an Integrated Control Strategy Applied in Two Brazilian Cities
da N. Regis, Ridelane Veiga Acioli, José Constantino Silveira, Maria Alice Varjal Melo-Santos, Wayner Vieira Souza, Candida M. Nogueira. Ribeiro, Juliana C. Serafim. da Silva, Antonio Miguel Vieira Monteiro, Cláudia M. F. Oliveira, Rosangela M. R. Barbosa, Cynthia Braga, Marco Aurélio Benedetti Rodrigues, Marilú Gomes N. M. Silva, Paulo Justiniano Ribeiro Jr., Wagner Hugo Bonat, Liliam César de Castro Medeiros, Marilia Sa Carvalho, André Freire Furtado
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0067682
Abstract: Aedes aegypti has developed evolution-driven adaptations for surviving in the domestic human habitat. Several trap models have been designed considering these strategies and tested for monitoring this efficient vector of Dengue. Here, we report a real-scale evaluation of a system for monitoring and controlling mosquito populations based on egg sampling coupled with geographic information systems technology. The SMCP-Aedes, a system based on open technology and open data standards, was set up from March/2008 to October/2011 as a pilot trial in two sites of Pernambuco -Brazil: Ipojuca (10,000 residents) and Santa Cruz (83,000), in a joint effort of health authorities and staff, and a network of scientists providing scientific support. A widespread infestation by Aedes was found in both sites in 2008–2009, with 96.8%–100% trap positivity. Egg densities were markedly higher in SCC than in Ipojuca. A 90% decrease in egg density was recorded in SCC after two years of sustained control pressure imposed by suppression of >7,500,000 eggs and >3,200 adults, plus larval control by adding fishes to cisterns. In Ipojuca, 1.1 million mosquito eggs were suppressed and a 77% reduction in egg density was achieved. This study aimed at assessing the applicability of a system using GIS and spatial statistic analysis tools for quantitative assessment of mosquito populations. It also provided useful information on the requirements for reducing well-established mosquito populations. Results from two cities led us to conclude that the success in markedly reducing an Aedes population required the appropriate choice of control measures for sustained mass elimination guided by a user-friendly mosquito surveillance system. The system was able to support interventional decisions and to assess the program’s success. Additionally, it created a stimulating environment for health staff and residents, which had a positive impact on their commitment to the dengue control program.
Gold Nanoparticle and Berberine Entrapped into Hydrogel Matrix as Drug Delivery System  [PDF]
Camila Rufino Souza, Henrique R. Oliveira, Wagner M. Pinheiro, Lubhandwa S. Biswaro, Ricardo B. Azevedo, Anderson J. Gomes, Claure N. Lunardi
Journal of Biomaterials and Nanobiotechnology (JBNB) , 2015, DOI: 10.4236/jbnb.2015.61006
Abstract: In this study the novel hydrogel loaded with gold nanoparticle (AuNP) enhanced the berberine (BS) release when compared with other formulations of hydrogel. Hydrogels are hydrophilic polymer networks having the capacity to absorb water, ranging from about twenty to thousand times their dry weight. BS is a natural product, a quaternary ammonium salt from the group of isoquinoline alkaloids found in medicinal plants as Berberis Vulgaris. BS has some activity against dysentery, hypertension, inflammation, and liver disease in China and Japan. In this work, BS was used as a model drug to study its association with different types of hydrogel composites of polyvinyl alcohol (BS-PVA 10%); gellan gum (BS-GG 2%), gellan gum-PVA crosslinked with cysteine (cys) (BSGG2%PVA2%cys) and gellan gum-PVA cosslinked with cysteine associated with gold nanoparticles (AuNP-BSGG2%PVA2%cys). Several parameters such as fraction of retained water (Wf), hydration percentage (%H), Swelling (DSw) and time course profile (t = 100%) (TC) were evaluated for all preparations. The results showed that the AuNP-BS-GG2%PVA2%cys was able to retain more water and swelling than the other preparations. The time course of release of the BS to the medium was greater for AuNP-BS-GG2%PVA2%cys making it a candidate to drug delivery studies in biological assays. Also Scanning Electron Microscopy (SEM) images of the surface of these hydrogel were performed. Furthermore, crosslink of the resulting hydrogels were investigated by Fourier Transform Infrared Spectroscopy (FTIR) and differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). Thus, briefly, the aim of this work was to study three composition of hydrogel loaded with BS and its composition in relation to addition to AuNP and evaluate its profile for further drug delivery application using the Surface Plasmonic Resonance (SPR) as a tool improving the drug release in the new hydrogel.
Nerves of the Mandibular Musculature of the Sand Tiger Shark Carcharias taurus (Rafinesque, 1810) (Chondrichthyes: Odontaspididae)
Silva Casas,André Luis da; Intelizano,Wagner; Fernandes de Souza Castro,Marcelo; Bonfim Mariana,Arani Nanci;
International Journal of Morphology , 2005, DOI: 10.4067/S0717-95022005000400017
Abstract: during this study, fifteen shark heads of sand tiger shark carcharias taurus (rafinesque, 1810) were analyzed. the studied material was obtained in the santos fishing terminal, s?o paulo, brazil. the heads dissection was focused on the characterization of the mandibular muscles and on the description of the mandibular branch of the trigeminal nerve. the c. taurus mandibular muscles are represented by: m. preorbitalis, m. levator palatoquadrati, m. quadratomandibularis and m. intermandibularis. the origin of the trigeminal nerve of c. taurus is located in a lateral portion of the medulla oblongata. in the orbita, the trigeminal nerve branches off to originate the mandibular branch that innervates the muscles which are derived from the mandibular arch. the proximal branches of the trigeminal nerve mandibular branch innervate the m. levator palatoquadrati. the muscles preorbitalis and quadratomandibularis receive fibers from the intermediate branches of the trigeminal nerve mandibular branch and the distal ramification of the mandibular branch can be visualized in the m. intermandibularis
Variabilidade genética de duas variedades de tilápia nilótica por meio de marcadores microssatélites
Moreira, Angela Aparecida;Hilsdorf, Alexandre Wagner Silva;Silva, Juliana Viana da;Souza, Vania Ribeiro de;
Pesquisa Agropecuária Brasileira , 2007, DOI: 10.1590/S0100-204X2007000400010
Abstract: the objective of this work was to evaluate the genetic variability of two nile tilapia strains (oreochromis niloticus), chitralada and red stirling, as well as its offsprings submitted to genetic enhancement programs, in intensive systems farming by microsatellites markers. thirty individuals of each parental strain, 30 crossbred (ch) individuals from chitralada and red stirling strains, and 30 individuals from red stirling progeny (rr) were used. five microsatellites loci were utilized: unh104, unh108, unh118, unh222 e unh231. low values of inbreeding were observed with a negative fis in both strains and their crossings. genetic differences between the two strains were detected through fst = 0.131 and rst = 0.130. the parental strains chitralada and red stirling presented 24.4% of genetic distance, which produced 23.5% of hybrid vigor in the ch stock.
Page 1 /291069
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.