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Search Results: 1 - 10 of 104961 matches for " WU Yu-hou "
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Numerical Simulation of Output Performance?in PEMFC

,CHEN Shi-zhong, WU Yu-hou

- , 2018, DOI: 10.13208/j.electrochem.170505
Abstract: 摘要 运用COMSOL软件模拟分析3种流道下的质子交换膜燃料电池输出性能. 在相同的操作条件下,比较了单蛇形流道、交指流道以及混合流道之间的性能差异,详细说明了3种流道下质子交换膜燃料电池输出性能差异的原因. 由模拟结果分析得出,混合流道输出性能最好,交指流道输出性能其次,单蛇形流道输出性能最差;混合流道的排水能力最好,氧气浓度分布的最均匀;混合流道阴极进出口氧气浓度差最小. 模拟结果对质子交换膜燃料电池结构的优化和设计具有重要的指导意义
A New Natural Hybrid of Paulownia (Scrophulariaceae)

Zhang Cun-yi,Zhao Yu-hou,

中国科学院研究生院学报 , 1995,
Biosensing Using Microring Resonator Interferograms
Shih-Hsiang Hsu,Yung-Chia Yang,Yu-Hou Su,Sheng-Min Wang,Shih-An Huang,Ching-Yu Lin
Sensors , 2014, DOI: 10.3390/s140101184
Abstract: Optical low-coherence interferometry (OLCI) takes advantage of the variation in refractive index in silicon-wire microring resonator (MRR) effective lengths to perform glucose biosensing using MRR interferograms. The MRR quality factor ( Q), proportional to the effective length, could be improved using the silicon-wire propagation loss and coupling ratio from the MRR coupler. Our study showed that multimode interference (MMI) performed well in broad band response, but the splitting ratio drifted to 75/25 due to the stress issue. The glucose sensing sensitivity demonstrated 0.00279 meter per refractive-index-unit (RIU) with a Q factor of ~30,000 under transverse electric polarization. The 1,310 nm DFB laser was built in the OLCI system as the optical ruler achieving 655 nm characterization accuracy. The lowest sensing limitation was therefore 2 × 10 ?4 RIU. Moreover, the MRR effective length from the glucose sensitivity could be utilized to experimentally demonstrate the silicon wire effective refractive index with a width of 0.45 mm and height of 0.26 mm.
Evaluation on Cartilage Morphology after Intra-Articular Injection of Titanium Dioxide Nanoparticles in Rats
Jiangxue Wang,Yu Gao,Ying Hou,Feng Zhao,Fang Pu,Xiaoyu Liu,Zhihong Wu,Yubo Fan
Journal of Nanomaterials , 2012, DOI: 10.1155/2012/452767
Abstract: Nanoscale wear particles would generate from orthopedic implants with nanoscale surface topography because of residual stress. In this study, the effect of TiO2 nanoparticles on articular cartilage was investigated by intra-articular injection in rats. Using contrast-enhanced high-resolution microcomputed tomography (micro-CT) technology, the decreased thickness of articular cartilage in distal femur was determined at 1, 7, 14, and 30 days after nanoparticle exposure. A strong linear correlation (=0.928, <0.0001) was observed with the results obtained by needle probe testing. After exposure to TiO2 nanoparticles, cartilage thickness showed time-dependent decrease, and cartilage volume was decreased too. Further, the histopathological examination showed the edema chondrocyte and shrinked nucleus in the radial and calcified zone of cartilage. The ultrastructure of articular cartilage implied that the chondrocyte was degenerated, expressing as the condensed chromatin, the dilated endoplasmic reticulum, and the rich mitochondria. Even, the fragments of ruptured endoplasmic reticulum were observed in the cytoplasm of chondrocytes at postexposure day 30. Results indicate that potential damage of articular cartilage was induced by particles existed in knee joint and imply that the biomonitoring should be strengthened in patients with prostheses replacement.
Application of DNA-based diagnostics in detection of schistosomal DNA in early infection and after drug treatment
Cen Wang, Lin Chen, Xuren Yin, Wanquan Hua, Min Hou, Minjun Ji, Chuanxin Yu, Guanling Wu
Parasites & Vectors , 2011, DOI: 10.1186/1756-3305-4-164
Abstract: This study compared loop-mediated isothermal amplification (LAMP) with conventional PCR as DNA-based diagnostic techniques for the early detection of schistosomal DNA and the evaluation of chemotherapy. The results showed that both PCR and LAMP assays targeting a 301 base pair (bp) sequence of the highly repetitive retrotransposon, SjR2, amplified DNA from schistosomes but were unable to distinguish between schistosome species. LAMP and conventional PCR were shown to amplify the target sequence of the SjR2-pCR2.1 recombinant plasmid template with limits of detection of 10-4 ng and 10-2 ng, respectively, thus demonstrating the superior sensitivity of the LAMP method. Schistosoma japonicum DNA was detected in all serum samples obtained from the three experimental groups at 1 week post-infection by LAMP assay, while the rate of detection by conventional PCR ranged from 50% to 66%. The potential application of PCR and LAMP assays for the evaluation of artesunate and praziquantel chemotherapy was investigated. PCR was shown to be less sensitive for detection of schistosomal DNA in drug-treated rabbit sera than the LAMP method.The data presented here indicate that LAMP is suitable for the detection of early infection in the groups primarily infected with Schistosoma japonicum, such as migrants, travellers, military personnel and the younger age groups. However, it is less suitable for evaluation of the efficacy of chemotherapy in the early stages because of its high sensitivity.Schistosomiasis remains one of the most common parasitic diseases, afflicting more than 200 million people worldwide [1]. In China, Schistosoma japonicum is the only causative species of schistosomiasis, which leads to hepatic periportal fibrosis and portal hypertension due to the deposition of Schistosoma japonicum eggs in tissues[2]. The morbidity associated with schistosomiasis has been successfully controlled in China through chemotherapy. However, it is difficult to eliminate this disease comp
Prediction and identification of mouse cytotoxic T lymphocyte epitopes in Ebola virus glycoproteins
Shipo Wu, Ting Yu, Xiaohong Song, Shaoqiong Yi, Lihua Hou, Wei Chen
Virology Journal , 2012, DOI: 10.1186/1743-422x-9-111
Abstract: Computer-assisted algorithms were used to predict H-2d-specific T cell epitopes in two species of EBOV (Sudan and Zaire) GP. The predicted peptides were synthesized and identified in BALB/c mice immunized with replication-deficient adenovirus vectors expressing the EBOV GP. Enzyme-linked immunospot assays and intracellular cytokine staining showed that the peptides RPHTPQFLF (Sudan EBOV), GPCAGDFAF and LYDRLASTV (Zaire EBOV) could stimulate splenoctyes in immunized mice to produce large amounts of interferon-gamma.Three peptides within the GPs of two EBOV strains were identified as T cell epitopes. The identification of these epitopes should facilitate the evaluation of vaccines based on the Ebola virus glycoprotein in a BALB/c mouse model.
Deformation Characteristics of Fine-grained Magnesium Alloy AZ31B Thin Sheet during Fast Gas Blow Forming
Pin hou Sun,Horng yu Wu,Shyong Lee,Chui-hung Chiu
Lecture Notes in Engineering and Computer Science , 2009,
{6-[2,5-Bis(chloromethyl)-3,4-dihydroxytetrahydrofuran-2-yloxy]-3-chloro-4,5-dihydroxy-3,4,5,6-tetrahydro-2H-pyran-2-yl}methyl acetate dihydrate
Jing-Yu Zhang,Xue-Hui Hou,Xue-Fen Wu
Acta Crystallographica Section E , 2010, DOI: 10.1107/s1600536809053173
Abstract: The title compound, C14H21Cl3O9·2H2O, is a disaccharide constructed from a galactose and a fructose. In the molecular structure, the tetrahydrofuran five-membered ring and tetrahydropyran six-membered ring assume envelope and chair conformations, respectively. An extensive O—H...O hydrogen-bonding network occurs in the crystal structure.
Dural repair with acellular biomembrane:multicenter clinical trials
Xiao-jing MU,Fang HOU,Min-ning XU,Yu-yan WU
Medical Journal of Chinese People's Liberation Army , 2011,
Abstract: Objective To evaluate the safety and efficacy of novel artificial dural acellular biomembrane(Zhenghai biomembrane) in dural repair.Methods A multicenter,randomized control trial was carried out with 155 patients undergone dural repair from Dec.2007 to Dec.2008.The patients were randomly divided into experimental group and control group and received dural repair with novel artificial dural acellular biomembrane and autologous fascia,respectively.There were 74 patients(34 males and 40 females;aged 46.6±14.6 years;reparation area 14.28±13.29cm2) in experimental group and 81 patients(36 males and 45 females;aged 44.8±12.7 years;reparation area 13.44±7.74cm2) in control group.Vital signs,laboratory indexes,cerebral CT/MRI scanning,incision healing and occurrence of complications were observed at 10 days and 1,3,6 months after operation,respectively,and the safety and efficacy of the novel artificial dural acellular biomembrane were evaluated.Results No cerebrospinal fluid leakage,intracranial infection or epilepsy was observed in both groups.Laboratory indexes and cerebral CT/MRI scanning were normal,and no repair material-related adverse events were found.The incidence of adverse events was 2.7% in experimental group and 3.7% in control group,and no significant difference was noticed between the two groups.Conclusion The safety and efficacy of dural repair with novel artificial dural acellular biomembrane are similar to that with autologous fascia,and may protect brain tissue timely.
Adjuvant percutaneous radiofrequency ablation of feeding artery of hepatocellular carcinoma before treatment
Yi-Bin Hou, Min-Hua Chen, Kun Yan, Jin-Yu Wu, Wei Yang
World Journal of Gastroenterology , 2009,
Abstract: AIM: To evaluate the feasibility and efficacy of percutaneous radiofrequency ablation (RFA) of the feeding artery of hepatocellular carcinoma (HCC) in reducing the blood-flow-induced heat-sink effect of RFA.METHODS: A total of 154 HCC patients with 177 pathologically confirmed hypervascular lesions participated in the study and were randomly assigned into two groups. Seventy-one patients with 75 HCCs (average tumor size, 4.3 ± 1.1 cm) were included in group A, in which the feeding artery of HCC was identified by color Doppler flow imaging, and were ablated with multiple small overlapping RFA foci [percutaneous ablation of feeding artery (PAA)] before routine RFA treatment of the tumor. Eighty-three patients with 102 HCC (average tumor size, 4.1 ± 1.0 cm) were included in group B, in which the tumors were treated routinely with RFA. Contrast-enhanced computed tomography was used as post-RFA imaging, when patients were followed-up for 1, 3 and 6 mo.RESULTS: In group A, feeding arteries were blocked in 66 (88%) HCC lesions, and the size of arteries decreased in nine (12%). The average number of punctures per HCC was 2.76 ± 1.12 in group A, and 3.36 ± 1.60 in group B (P = 0.01). The tumor necrosis rate at 1 mo post-RFA was 90.67% (68/75 lesions) in group A and 90.20% (92/102 lesions) in group B. HCC recurrence rate at 6 mo post-RFA was 17.33% (13/75) in group A and 31.37% (32/102) in group B (P = 0.04).CONCLUSION: PAA blocked effectively the feeding artery of HCC. Combination of PAA and RFA significantly decreased post-RFA recurrence and provided an alternative treatment for hypervascular HCC.
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