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Search Results: 1 - 10 of 235984 matches for " W E Sadoh "
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Physicians management of sore throat in children in Benin City, Nigeria
W.E Sadoh, A.M Akinsete
Nigerian Journal of Clinical Practice , 2009,
Abstract: Sorethroat is a common reason for presentation in primary paediatric care. Because only minority of cases of pharyngitis is caused by bacteria, physicians have been guided by various recommendations on the judicious use of antibiotics to avoid overprescription. In the absence of guidelines, the treatment approaches between physicians may differ. The management of children with sorethroat by physicians inBeninCity,Mid-WesternNigeriawas evaluated. The experience and practice of 25 paediatricians and 30 non paediatricians who routinely attend to children with sorethroat in Benin metropolis, Nigeria were evaluated with the aid of a self administered questionnaire. Information sought for included biodata, empirical antibiotic prescription. The choice of antibiotic and complications of pharyngitis encountered in practice. Majority of respondents 31(56.4 %) considered viruses as the commonest cause of pharyngitis. Despite this an equal proportion 31(56.4 %) treated children with sorethroat empirically with antibiotics. Of these, significantly more paediatricians 19(61.3%) than non paediatricians 12(38.7%) considered viruses the commonest cause of pharyngitis, P = 0.013. CI (0.10 0.63). Almost three quarter (72.7 %) of respondents examine the throat of the childrenwhile only 18.2%obtained throat swab formicrobiological analysis. The 24 doctorswho did not treat empiricallywould prescribe antibiotic if the patient has purulent pharyngeal exudates, fever and adenitis.Augmentin and cefuroximewere themost prescribed antibiotics. Alot of children served by these doctors receive antibiotic needlessly from empirical antibiotic treatment of pharyngitis.National guidelines on appropriate antibiotic use is needed to promote rational use of antibiotics and reduce antibiotic overuse.
Attitude of Health-Care Workers to HIV/AIDS
A E Sadah, A O Fawole, W E Sadoh, A O Oladimeji, O S Sotiloye
African Journal of Reproductive Health , 2006,
Abstract: The current 5% prevalence rate of HIV in Nigeria represents a significant population of people living with HIV/AIDS (PLWHA). Discrimination against PLWHA has profound impact on the care and support required fro their optimal management particularly in resource-constrained settings. The study sought to assess the knowledge of health-care providers about HIV/AIDS, determine the potential for discrimination in the provision of services based on patients\' HIV sero-status and review the factors that may contribute to such attitude. Self administered semi-structured questionnaires were administered to respondents who were selected by multi-stage sampling technique. The questionnaires explored the respondents\' knowledge about HIV and their attitude and practice regarding PLWHA. Three hundred and forty-five questionnaires were completed. Only 77.1% correctly identified breastfeeding as a source of HIV transmission; 5.2% and 26% respectively thought transmission was possible through mosquito bite and handshake. About 10% and 15% respectively among trained nurses and auxiliary nurses were unaware that HIV could be transmitted to the child during delivery. Some 13.9% and 12.7% of respondents respectively were unwilling to take vital signs and carry out physical examination on PLWHA. Compared to physicians, trained nurses and auxiliary nurses were more likely to deny services based on HIV ero-status. Negative attitude was more likely if the source of the HIV infection was from homosexual exposure or bisexual indiscretion. The health-care workers studied manifested certain attitudes that are potentially discriminatory of PLWHA well-coordinated continuing education of HIV/AIDS for all categories of health-care workers is recommended as a vital strategy in the crusade against the epidemic. African Journal of Reproductive Health Vol. 10 (1) 2006: pp. 39-46
A 4 Year Review of Neonatal Outcome at the University of Benin Teaching Hospital, Benin City
A.I Omoigberal, W.E Sadoh, D.U Nwaneri
Nigerian Journal of Clinical Practice , 2010,
Abstract: Background: Neonatal morbidity and mortality rates reflect a nation's socio-economic status, the efficiency and effectiveness of health care services. This important indicator is useful in planning for improved healthcare delivery. A four year review of neonatal outcome was therefore conducted in the special care baby Unit (SCBU) of University of Benin Teaching Hospital (UBTH). Methods and Subjects: The study was done between 2003 and 2006 and sought to review the morbidity, mortality, salvage rate of low birth weight babies and outcome of all inborn and outborn babies admitted into the SCBU of UBTH. The biodata, birth weight, sex, APGAR scores and reasons for admissions and outcome were abstracted from case notes/admission records. Result: A total of 3075 babies were admitted to the unit during the period under review. 2602 (84.6%) were inborn while 473 (15.4%) were out-born. There were more males 1676 (54.6%). There were 855(27.8%) preterm babies of which 803(26.1%) were low birth weight babies. Neonatal sepsis, severe birth asphyxia, pre-maturity and neonatal tetanus were the most common morbidities suffered by the neonates. Mortality was recorded amongst 625 (20.3%) babies. Mortality rate was significantly higher amongst the out-born than in born babies, P value < 0.0001. Conclusion: The neonatal mortality rate in this study is high. The morbidity profile observed in the study is attributable to preventable causes. Of note is the contribution of NNT to morbidity and mortality. Strengthening of linkages in perinatal care, improving maternal emergency obstetric care and neonatal resuscitation skills are proposed measures to reduce neonatal mortality. Key Words: Neonatal mortality, morbidity, Prematurity, birth asphyxia, Neonatal tetanus
Attitude of health care workers to patients and colleagues infected with human immunodeficiency virus
A Sadoh, W Sadoh, AO Fawole, A Oladimeji, O Sotiloye
SAHARA J (Journal of Social Aspects of HIV/AIDS Research Alliance) , 2009,
Abstract: Discrimination against persons living with HIV/AIDS in hospital settings has been documented. This study examined the attitude of health care workers (HCWs) to nurses, doctors and patients infected with HIV. A total of 345 respondents selected by multistage sampling techniques were surveyed, using a semi-structured questionnaire, which explored respondents’ attitude to HIV-infected patients and colleagues with HIV/AIDS. HCWs were unwilling to accept that medical procedures be carried out on them by HIV-infected doctors and nurses, with almost 80% refusing surgery or assistance at surgery on them by an HIV-infected doctor or nurse. They were also significantly more unwilling to accept that medical procedures be carried out on them by an infected colleague, compared with their carrying out the same procedure on an HIV-infected patient. Thus, HCWs seemed to believe that the risk of contracting HIV was higher if an infected HCW were to perform medical procedures on them, and fear of contracting HIV seemed to be the driving force for their negative attitudes. Education on occupational risks of HIV, provision of a safe working environment with enforcement of universal precautions, as well as provision of post-exposure prophylaxis are suggested as ways to enable HCWs to change their attitudes.
Congenital heart diseases at the University of Benin Teaching Hospital
MO Ibadin, WE Sadoh, W Osarogiabon
Nigerian Journal of Paediatrics , 2005,
Abstract: No Abstract.
The Diagnostic Value of Both Troponin T and Creatinine Kinase Isoenzyme (CK-MB) in Detecting Combined Renal and Myocardial Injuries in Asphyxiated Infants
Wilson E. Sadoh, Charles O. Eregie, Damian U. Nwaneri, Ayebo E. Sadoh
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0091338
Abstract: Background Troponin T (cTnT) and Creatinine Kinase Isoenzyme (CK-MB) are both markers of myocardial injuries. However, CK-MB is also elevated in acute kidney injury. Objective The diagnostic value of both cTnT and cardiac CK-MB in combined myocardial and acute kidney injuries (AKI) in asphyxiated neonates was evaluated. Method 40 asphyxiated infants and 40 non-asphyxiated controls were consecutively recruited. Serum levels of cTnT, CK-MB and creatinine were measured. Myocardial injury and AKI were defined as cTnT >95th percentile of the control and serum creatinine >1.0 mg/dl respectively. Results Of the 40 subjects, 9 (22.50%), 8 (20.00%) and 4 (10.00%) had myocardial injury, AKI and combined AKI and myocardial injuries respectively. The mean cTnT and CK-MB values were highest in infants with combined AKI and myocardial injuries. The Mean cTnT in infants with AKI, myocardial injury and combined AKI and myocardial injuries were 0.010±0.0007 ng/ml, 0.067±0.040 ng/ml and 0.084±0.067 ng/ml respectively, p = 0.006. The mean CK-MB in infants with AKI, myocardial injury and combined AKI and myocardial injuries were 2.78±0.22 ng/ml, 1.28±0.11 ng/ml and 4.58±0.52 ng/ml respectively, p = <0.0001. Conclusion In severe perinatal asphyxia, renal and myocardial injuries could co-exist. Elevated cTnT signifies the presence of myocardial injury. Elevated CK-MB indicates either myocardial injury, AKI or both. Therefore renal injury should be excluded in asphyxiated infants with elevated CK-MB.
Experiences of HIV positive mothers who chose not to breastfeed their babies in Nigeria
WE Sadoh, AE Sadoh
African Journal of Reproductive Health , 2009,
Abstract: HIV positive mothers, who choose not to breastfeed their babies in a predominantly breastfeeding community would face a number of barriers. This study looked at the experiences of HIV positive mothers who chose the no breastfeeding option. Consecutive HIV positive mothers who opted not to breastfeed their infants after infant feeding counselling and whose infants were attending the HIV programme at the University of Benin Teaching Hospital, Benin City, Nigeria were recruited for the study. Disclosure of HIV serostatus and adherence to no breastfeeding options were evaluated using an interviewer administered structured questionnaire. Of the 62 mothers recruited for the study, 57 (91.94%) had disclosed their serostatus to at least their partners. Most partners 42 (93.33%) were supportive while three mothers were divorced following disclosure. Thirteen (20.97%) mothers could not comply with no breastfeeding. Non disclosure of serostatus, pressure from extended family and token breastfeeding mitigate against adhering to no breastfeeding by HIV positive mothers (Afr J Reprod Health 2009; 13[1]:27-35).
Diphtheria mortality in Nigeria: the need to stock diphtheria antitoxin
AE Sadoh, WE Sadoh
African Journal of Clinical and Experimental Microbiology , 2011,
Abstract: INTRODUCTION: Diphtheria had been a major of cause of childhood mortality until the advent of an effective vaccine. Even in Nigeria with low to moderate coverage with the third dose of DPT the number of reported cases of diphtheria had been reducing. However, in a recent report we noted an increase in the incidence of diphtheria. The mainstay of management of diphtheria is the Diphtheria antitoxin. Diphtheria antitoxin is not available in Nigeria. We present the mortalities from diphtheria to highlight the need to stock the diphtheria antitoxin. METHODOLOGY: A review of the case notes of patients managed for diphtheria between August 2008 and 2010 was done and relevant data extracted. RESULTS: Nine cases of diphtheria were seen and three mortalities were recorded giving a mortality rate of 33.3%. One of the deaths was from myocardial involvement and acute renal failure while another was from possible septicaemia. The third mortality occurred at home after discharge from hospital DISCUSSION: Most of the symptoms of diphtheria are due to the effects of the diphtheria exotoxin. The non availability of the antitoxin for the management of these children contributed to their mortality. CONCLUSION: As long as diphtheria remains uneradicated the need for the antitoxin is imperative.
Need for a clinical decision rule for the management of pharyngitis in Nigeria
WE Sadoh, AE Sadoh
Nigerian Journal of Paediatrics , 2013,
Abstract: Pharyngitis is a common reason for presentation in the hospital by children. Although viral aetiology is the commonest, Group A Streptococcus is the most important cause of and reason for antibiotic treatment of pharyngitis. The fact that GAS causes the non suppurative sequalae of rheumatic fever and acute glomerulonephritis perhaps drives the empirical antibiotic treatment of most cases of pharyngitis. The unnecessary antibiotic treatment contributes to antibiotic resistance, a major public health problem. While it is desirable to do throat culture to guide the physician’s management of each case, the required laboratory skill is unavailable in most clinical settings in Nigeria. A clinical decision rule (CDR) which is a clinical tool that helps guide physicians in the management of conditions such as pharyngitis, have been shown to be helpful in managing pharyngitis in other countries. It reduces the number of unnecessary antibiotic prescriptions and has a high sensitivity and specificity in distinguishing GAS from non GAS pharyngitis. Currently there are no guidelines or CDR for the management of pharyngitis in Nigeria, there is an urgent need to derive, validate and implement a CDR to guide the treatment of pharyngits.
Natural history of ventricular septal defects in Nigerian children
WE Sadoh
South African Journal of Child Health , 2010,
Abstract: Introduction. Ventricular septal defect (VSD) is a common congenital heart disease (CHD). Spontaneous closure of the VSD may occur, depending on the type and size of defects. This study was conducted to determine the natural history of VSD in a group of Nigerian children. Subjects and methods. Sixty-one children diagnosed with VSD were prospectively studied at a tertiary centre in Nigeria until they were 2 years old. They had regular two-dimensional (2D) and Doppler echocardiography evaluations for the VSD size and closure. Results. Most (35 – 57.4%) of the patients were female, their mean age at presentation was 11.2±5.2 months, and the most common type of VSD was the perimembranous (39 – 63.9%). Almost half (28 – 45.9%) of the patients had spontaneous closure. The spontaneous closure rate was highest in muscular VSD (82.4%) and in small defects (95.0%). Incidental presence of a murmur, absence of heart failure and bronchopneumonia were good clinical predictors of closure. Only 3 (4.9%) patients had surgery abroad. There were 2 (3.3%) deaths from bronchopneumonia and bacterial endocarditis. Conclusion. Spontaneous closure readily occurs in small-sized defects and muscular VSDs. However, most patients with moderate to large VSDs are confined to long-term medical management, highlighting the need for indigenous surgical capacity in Nigeria.
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