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THE NEWS IN THERAPY OF AUTISM
Vladimir TRAJKOVSKI
Journal of Special Education and Rehabilitation , 2004,
Abstract: There is no specifically marked medicine for the treatment of autism. A number of approaches have been used in evaluating the safety and efficiency of pharmacological treatments of both children and adults with autism. Two study parameters are particularly important, the presence of “blind” and control groups. The highest quality studies utilize equally “blind” and control procedures as well. They have to be performed at multiple sites with a large number of subjects.Research evaluating medicine proposed for treatment of autism, is on the increase. There is accelerated emphasis on medicine testing and better information on treatments should be more available than in the past. In this article, the following classes of medicine and therapies will be discussed: possible future medicine treatments - such as oxytocin, tetrahydrobiopterin and ampakines, hormone therapies, anti-yeast therapies, vitamin therapies, dimethylglycine, alpha lipoic acid and diet therapies.
ETIOLOGY OF AUTISM
Vladimir TRAJKOVSKI
Journal of Special Education and Rehabilitation , 2004,
Abstract: Although there is good evidence that autism is a multifactorial disorder, an adequate understanding of the genetic and nongenetic causes has yet to be achieved. With empirical research findings review is made to evidence on possible causal influences. Much the strongest evidence concerns the importance of susceptibility genes, but such genes have yet to be identified. Specific somatic conditions (tuberous sclerosis and the fragile X syndrome) account for a small proportion of cases. Over recent decades there has been a major rise in the rate of diagnosed autism. The main explanation for this rise is to be found in better ascertainment and a broadening of the diagnostic concept. Progress on the elucidation of the causes of autism will be crucially dependent on the combination of epidemiology with more basic science laboratory studies.
D-r Goran Ajdinski: “DEVELOPMENTAL CHARACTERISTICS WITH EASY MENTALLY RETARDED STUDENTS”
Vladimir TRAJKOVSKI
Journal of Special Education and Rehabilitation , 2000,
Abstract:
DEFECTOLOGY STUDENT’S SEMINAR WITH INTERNATIONAL PARTICIPATION
Vladimir TRAJKOVSKI
Journal of Special Education and Rehabilitation , 2000,
Abstract:
MEDICAL GENETICS AND ETHICS
Vladimir TRAJKOVSKI
Journal of Special Education and Rehabilitation , 1999,
Abstract: Fast development of medical genetics and it’s subdisciplines is noticed in last thirty years. Modern diagnostic methods made possible to establish human genome and its impairment. In human genetics, ethic is main principle in working. Ethic is science about biggest goodness for human or society, and its aim pro-tecting human health.Today's conditions for leaving and science development open a wide way for ethical approaches, but also for non-ethical manipulations with human even before his conception. We must keep to attitude that without law, with our behavior will must conduct our conscience. It is best to have neutral eugenetic attitude, which allows free ethical choice of each individual, in any case, for the well being of man.
AUTISM ON THE INTERNET
Vladimir TRAJKOVSKI
Journal of Special Education and Rehabilitation , 2000,
Abstract: The Internet as the world wide information system is a global information network that provides instantly communication between a million users through its services. The Internet can be used in any science discipline especially in medicine. The aim of this paper is to show the possibilities of Internet in studying all the aspects of autism syndrome, introducing the public with some web-sites which treats autism and presenting the one and only web-site in Macedonia called Autism-Macedonia. In this paper are elaborated the Internet functioning model, some areas that can be found on Internet, some Internet services with their addresses and searching by Internet. This paper is dedicated to the widest medical and defectology public and the parents of the children with autism. The Internet is the “instrument” in the hands of the doctors, defectologysts or any other professionals. They can’t imagine their scientific work without it. It’s an “excellent weapon” in the hands of any person who wants to enrich its knowledge.
Dr. Anastas Lakoski: "PSYCHOGENETICS"
Vladimir TRAJKOVSKI
Journal of Special Education and Rehabilitation , 1999,
Abstract:
FIRST "STUDENTS" DEFECTOLOGICAL DAYS
Vladimir TRAJKOVSKI
Journal of Special Education and Rehabilitation , 1999,
Abstract:
THE MEANING OF MITOCHONDRIAL DISEASES IN DEFECTOLOGY
Vladimir TRAJKOVSKI
Journal of Special Education and Rehabilitation , 1999,
Abstract: Mitochondrial diseases are a group of disorders characterized by morphological or functional defects of the mitochondria, the organelles producing most of our cellular energy. As the only extranuclear site carrying genetic information, the mitochondria add an important chapter in to the inheritance patterns of genetic disease. Because the mitochondria produce energy in all the tissues, symptoms resulting from mt DNA mutations may originate from any organ system, and the clinical spectrum of mitochondrial diseases has expanded to virtually all branches of medicine.Diagnosis of mitochondrial dysfunction may be difficult with currently available tools, however, measuring respiratory chain enzyme activities, mt DNA levels, and searching for mt DNA mutations and deletions are specific tests.Treatment of these disorders is currently empirical, involving agents that may improve the redox status of mitochondria, promote electron flow, or act as mitochondrial antioxidants.Limited data are available for genotype/phenotype correlation's in disorder caused by mt DNA mutations, therefore, prenatal diagnosis for mt DNA mutations has been hindered by an inability to predict accurately the clinical severity expected from a mutant load measured in fetal tissue
Evaluation of the Language Communicational Skills of Persons with Broca's Aphasia as a Concomitance from Cerebrovascular Insult
Ilija Todorov , Vladimir Trajkovski
Journal of Special Education and Rehabilitation , 2011, DOI: 10.2478/v10215-011-0002-x
Abstract: Persons with Broca's aphasia socialize in society much faster, because of the early rehabilitation treatment using the speech therapy. In the beginning of the illness, the voice production is arduous and the speech is with variable prosody. The patient expresses himself exceptionally with nouns and working verbs, also using mimics and gestures. The main purpose of the research is the evaluation of the communicational language skills of persons with Broca's aphasia, even in the acuteness of the illness. The goal is also to examine and establish the opinion of persons with Broca's aphasia, their family members and medical staff regarding the use of early rehabilitation treatment with speech therapy. The basic tasks of this research are to determine whether the disturbance of verbal interaction is often followed with speech apraxia and agrammatism among the persons suffering from Broca's aphasia. Two types of examinees are included in the research. The survey was conducted in Skopje and in a period of three months. The data gained from the research are grouped, tabulated, processed and graphically shown using the program Microsoft Office Excel 2003. The differecnces in the data of the examinees is analyzed with Chi square test with level of significance p<0.05. From the analyzis and interpretation of the results we can see that persons with Broca's aphasia, although produce incomplete sentences, they verbalise sentences with content which are informative for their interlocutor and the auditory understending is less demaged than the expressive funcion of the speech. In conclusion, the study found that early rehabilitation treatment using speech therapy for persons with Broca's aphasia resulted in faster improvements and better capabilities for speech-language communicational skills.
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