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Search Results: 1 - 10 of 26505 matches for " Vitor Araújo Goulart "
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Cutaneous Vasculitis with Renal Impairment in Octogenarian  [PDF]
Thiago Sande Miguel, Bruna Sande Miguel, Vinicius Sande Miguel, Jair Baptista Miguel, Sebasti?o Celio Horta Coelho Filho, Nayrton Kalys Cruz dos Anjos, Lívia Cristina de Melo Pino, Paola Stephanie Azevedo de Sá, Vitor Araújo Goulart, Daniel Almeida da Costa
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.56004
Abstract: Henoch-Schönlein purpura is a vasculitis of small vessels, characterized by tissue deposition of IgA, affecting predominantly the skin, intestine, joints and kidneys. It mainly affects the pediatric age group, especially from 2 to 11 years old. Most often, it is preceded by episode of upper airway infection from days to weeks. The most common clinical manifestations are purpuric cutaneous lesions located in the lower limbs and buttocks, abdominal pain in colic, nausea, vomiting, diarrhea, in addition to arthralgia/arthritis, usually with spontaneous resolution. Renal impairment usually manifests with hematuria and proteinuria, and renal function may also be impaired. The case described refers to a female patient, 86 years old, with a previous history of infection of the upper airways, followed by purpura in the lower limbs and renal impairment: serum creatinine 3.1 mg/dL (N 0.5 - 1.2 mg/dL); glomerular filtration rate 15 ml/min (N > 60 ml/min); urea 118 mg/dL (N < 40 g/dL); proteinuria 4.497 mg/24h. The present report aims to draw attention to the occurrence of Henoch-Schönlein purpura in an atypical age group, with significant renal impairment, improvement only with conservative treatment, thus avoiding the use of immunosuppressants and the risks of immunosuppression and toxicity related to such drugs.
Exponential decay of correlations for nonuniformly hyperbolic flows with a C^{1+α} stable foliation, including the classical Lorenz attractor
Vitor Araújo,Ian Melbourne
Mathematics , 2015,
Abstract: We prove exponential decay of correlations for a class of $C^{1+\alpha}$ uniformly hyperbolic skew product flows, subject to a uniform nonintegrability condition. In particular, this establishes exponential decay of correlations for an open set of geometric Lorenz attractors. As a special case, we show that the classical Lorenz attractor is robustly exponentially mixing.
Cytotoxic, trypanocidal activities and physicochemical parameters of nor-2-lapachone-based 1,2,3-triazoles
Silva Júnior, Eufranio N. da;Moura, Maria Aline B. F. de;Pinto, Antonio V.;Pinto, Maria do Carmo F. R.;Souza, Maria Cecília B. V. de;Araújo, Ana J.;Pessoa, Claudia;Costa-Lotufo, Letícia V.;Montenegro, Raquel C.;Moraes, Manoel Odorico de;Ferreira, Vitor F.;Goulart, Marilia O. F.;
Journal of the Brazilian Chemical Society , 2009, DOI: 10.1590/S0103-50532009000400007
Abstract: the cytotoxicities of five nor-2-lapachone-based 1,2,3-triazoles and the precursor azidonaphthoquinone were assayed against six neoplasic cancer cell lines: sf-295 (central nervous system), hct-8 (colon), mdamb-435 (melanoma), hl-60 (leukaemia), pc-3 (prostate) and b-16 (murine melanoma). ic50 values ranging from 0.43 to 9.48 μm were obtained. 3-(4-(1-hydroxycyclohexyl)-1h-1,2,3-triazol-1yl)-2,2-dimethylnaphtho[1,2-b]furan-4,5-dione proved highly cytotoxic to mdamb-435, with ic50 even lower than the one from doxorubicin (positive control). in an attempt to correlate physicochemical parameters (reduction potentials and calculated log p) with cytotoxic activity, electrochemical studies were conducted in acetate buffer, ph 4.5, using a vitreous carbon electrode and calculated log p values were obtained. despite the absence of a structural conjugative interaction between the two systems (quinone and triazole), the heterocyclic group was found to influence the voltammetric behaviour, as indicated by anodic shifts in the reduction potentials. no correlation was found between epic and cytotoxicity. in contrast, a comparison of epic with previously reported trypanocidal activities reconfirmed the trend for higher activity coupled with better quinone electrophilicity (> epic).a leading term in the correlation of cytoxicity, despite the absence of a linear correlation, was the calculated log p: the lower the lipophilicity, the lower the cytoxicity (> ic50).
SIG nas nuvens para empresas florestais / Cloud GIS for forestry companies
Marcelo Antunes Araújo,Juliana Aoki,Bruna Goulart Duarte
Ambiência , 2012,
Abstract: O presente artigo descreve um panorama geral de conceitos, servi os e aplica es na área florestal da utiliza o do Geographic Information System (GIS) por meio da computa o em nuvem, o chamado Sistema de Informa o Geográfica (SIG) na nuvem. Este modelo de distribui o de recursos amplia as capacidades atuais das empresas em prover a infraestrutura necessária ao processamento geográfico com investimentos adequados e portanto minimizando custos, além de fortalecer as atuais oportunidades de presta o de servi os remotos de SIG para as pequenas e médias empresas que desejam ter acesso a sistemas mais avan ados tecnologicamente.AbstractThis paper presents an overview of concepts, services and applications in forestry use of GIS through cloud computing, called Cloud GIS. This resource allocation model extends the capabilities of existing companies in providing the necessary infrastructure to geographic processing with appropriate investments and therefore minimizing costs, besides strengthening the existing opportunities to provide services to remote GIS for small and medium forest businesses who want access the most technologically advanced systems.
O ensino de conteúdos atitudinais na forma??o inicial do enfermeiro
Nosow, Vitor;Püschel, Vilanice Alves de Araújo;
Revista da Escola de Enfermagem da USP , 2009, DOI: 10.1590/S0080-62342009000600015
Abstract: qualitative research, exploratory and descriptive, had the aim to investigate teaching of the attitudinal content on training of nurses by professors in a public school of nursing. it was held at the escola de enfermagem da usp, with nine teachers in nursing baccalaureate and members of grupo de apoio pedagógico. after approval of the project, data were collected through semi-structured interviews and analyzed using content analysis. for want of insertion of the attitudinal contents in the courses programs, they are worked by the individual teacher's initiative that uses different strategies in the classroom or on the practice field. in the process of teaching teachers found possibilities and limitations related to the institution, teachers and students. the major difficulty is the assessment of attitudinal content. work attitudes as learning objectives and build the right tools is the goal to be considered in the new curriculum.
INFLUêNCIA DO CANAL MARINHO DA ILHA DE VITóRIA-ES SOBRE A BIOMASSA DE ALGAS DO GêNERO Ulva sp. (CHLOROPHYTA, ULVALES)
Vitor Araújo-Lima,Nuno Gouvea de Souza Caliman
Perspectivas Online : Biológicas e Saúde , 2012,
Abstract: As informa es a respeito do tamanho da biomassa de Ulva sp aqui apresentadas têm por objetivo contribuirpara o conhecimento deste gênero, focando o fornecimento de subsídios para estratégias de conserva o doecossistema aquático. O objetivo deste estudo foi observar se ocorre diferen a na biomassa de Ulva sp emdiferentes pontos localizados próximos a um canal com polui o organica de esgoto. As condi es doambiente ou fatores abióticos, como a polui o, induzem uma serie de respostas fisiológicas em organismos,que determinam se o ambiente físico é habitável ou n o . Foram escolhidos 3 pontos alinhados em rela o aoponto de polui o, de modo que a incidência de polui o seria maior no primeiro do que no segundo e maiorno segundo do que no terceiro (200 metros equidistantes). Cinco quadrantes foram retirados de cada ponto,triados e pesados. No presente estudo foi evidenciado uma resposta fisiológica quanto ao crescimento da algaverde do gênero Ulva conhecida como alface-do-mar. Observa-se que os pontos dois e três n o foram t oafetados quanto o ponto um, este localizado mais próximo da polui o respondeu tendo metade do pesoencontrado nos outros pontos.
Defini es para o resultado de enfermagem comportamento de preven o de quedas: uma revis o integrativa
Allyne Fortes Vitor,Thelma Leite de Araújo
Revista Eletr?nica de Enfermagem , 2011,
Abstract: Devido à necessidade de mensurar o risco de quedas em concordancia à linguagem padronizada de enfermagem, foi selecionado o resultado de enfermagem Comportamento para Preven o de Quedas da Nursing Outcomes Classification (NOC), com objetivo de identificar evidências sobre seus elementos, mensura o, compara o com indicadores existentes e construir defini es constitutivas. Foi efetuada revis o integrativa entre abril e novembro de 2009, mediante identifica o da quest o, estabelecimento de critérios de inclus o/exclus o, extra o das informa es, avalia o, interpreta o e síntese. Destacaram-se pesquisas transversais e perspectivas de especialistas. Os indicadores Uso de recursos de corre o da vis o e Uso de sapatos amarrados e do tamanho adequado foram considerados insuficientes para avaliar fatores de risco como déficits sensoriais e roupas/cal ados inadequados. Percebe-se que algumas defini es precisam ser melhor desenvolvidas e que esse resultado de enfermagem merece refinamento sobretudo referente aos indicadores. Foram identificados 22 indicadores e defini es foram propostas baseadas nas evidências da literatura.
Hydralazine Hydrochloride: An Alternative Complexometric Reagent for Total Iron Spotometric Determination  [PDF]
Arlan de Assis Gonsalves, Cle?nia Roberta Melo Araújo, Cristiane Xavier Galhardo, Marília Oliveira Fonseca Goulart, Fabiane Caxico de Abreu
American Journal of Analytical Chemistry (AJAC) , 2011, DOI: 10.4236/ajac.2011.27089
Abstract: An alternative spectrophotometric method has been developed for total iron determination using flow injection analysis (FIA). The procedure is based on the coordination reaction between hydralazine and Fe2+ ions, which results in the formation of a purple complex monitored at 538 nm. For determination of total iron, Fe3+ ions were reduced using ascorbic acid. Under optimized conditions, a linear calibration graph (0.1 - 6.0 ?g?ml–1; n = 6) was obtained. The method allows LOD (3? of blank/slope = 0.06 ?g?ml–1) and LOQ (10? of blank/slope = 0.22 ?g?ml–1). The RSD ((s/ ) × 100) for a mixed standard containing 0.60 ?g?ml–1 Fe2+ and Fe3+ was 0.10% (n = 10). Recoveries of spiked samples were 94.3% - 106.0%. The analytical frequency was 60 h–1. The effect of possible interferences has been studied. The procedure was successfully applied for analysis of environmental samples. The real samples results were comparable with those obtained by the official method considering a paired t-test and 95% of confidence level.
The -786T>C promoter polymorphism of the NOS3 gene is associated with prostate cancer progression
Karina Marangoni, Thaíse G Araújo, Adriana F Neves, Luiz R Goulart
BMC Cancer , 2008, DOI: 10.1186/1471-2407-8-273
Abstract: This study aimed evaluating the NOS3 promoter polymorphisms by PCR-SSCP and sequencing, associating genotypes and haplotypes with NOS3 expression levels through semi-quantitative RT-PCR, and with PCA3 mRNA detection, a specific tumor biomarker, in the peripheral blood of pre-surgical samples from 177 patients; 83 PCa and 94 BPH.Three novel SNPs were identified -764A>G, -714G>T and -649G>A in the NOS3 gene promoter region, which together with the -786T>C generated four haplotypes (N, T, C, A). NOS3 gene expression levels were affected by the -786T>C polymorphism, and there was a 2-fold increase in NOS3 levels favored by the incorporation of each C allele. NOS3 levels higher than 80% of the constitutive gene expression level (B2M) presented a 4-fold increase in PCa occurrence.The -786T>C polymorphism was the most important promoter alteration of the NOS3 gene that may affect the PCa progression, but not its occurrence, and the incorporation of the C allele is associated with increased levels of NOS3 transcripts. The NOS3 transcript levels presented a bimodal behavior in tumor development and may be used as a biomarker together with the PCA3 marker for molecular staging of the prostate cancer.Enzymes responsible for nitric oxide (NO) synthesis constitute a family with at least three distinct isoforms, inducible, neuronal and endothelial [1]. The nitric oxide synthase 3 (NOS3) is located at the 7q35-q36 chromosome locus and the characterization of the 5'-flanking genomic region indicates that the NOS3 promoter is 'TATA-less'. This feature has been described for genes such as housekeeping genes and is usually associated with multiple transcription start sites. The NO synthase mRNA does not correspond to these criteria and the presence of specific potential transcription factor binding sites in the promoter could account for the cell specificity of its transcription [2].The NOS3 seems to have an important role in vascular development, maintenance of the vascular tone and
Espécies raras de Phallales (Agaricomycetidae, Basidiomycetes) no Nordeste do Brasil
Leite, Anileide Gomes;Silva, Bianca Denise Barbosa;Araújo, Ricardo Souza;Baseia, Iuri Goulart;
Acta Botanica Brasilica , 2007, DOI: 10.1590/S0102-33062007000100011
Abstract: six interesting species of phallales are recorded from the atlantic rainforest: asero? floriformis baseia & calonge, geastrum setiferum baseia, ileodictyon cibarium tulasne ex raoul, laternea triscapa turpin, phallus pygmaeus baseia and staheliomyces cinctus e. fischer. a key and comments on taxonomy and ecology of these species are also provided.
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