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Search Results: 1 - 10 of 9870 matches for " Vinicius Daher Alvares;Barbosa "
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Deriva??o gástrica em Y-de-Roux e a atividade inflamatória do tecido adiposo
Valezi, Antonio Carlos;Cabrera, Edilson Jo?o;Delfino, Vinicius Daher Alvares;Barbosa, Decio Sabbatini;Mali Junior, Jorge;Menezes, Mariano de Almeida;
Revista do Colégio Brasileiro de Cirurgi?es , 2011, DOI: 10.1590/S0100-69912011000300004
Abstract: objective: to evaluate the oxidative stress and inflammatory markers in obese patients before and after roux-en-y vertical banded gastroplasty. methods: we studied 20 class iii obese patients undergoing roux-en-y vertical banded gastroplasty, seven men and 13 women, mean age 39 years, and 20 non-obese subjects, nine males and 11 females, mean age 38 years. we determined the plasma levels of malondialdehyde, stress an index, total antioxidant capacity, catalase, reduced and oxidized glutathione and inflammatory markers (c reactive protein and á-1 acid glycoprotein). in the obese group, these parameters were determined before and 2, 6 and 12 months after gastroplasty. results: preoperatively, the obese group showed elevated levels of inflammatory markers of oxidative stress (malondialdehyde levels and stress index) and lower levels of indicators of antioxidant defense compared to the control group. weight loss was accompanied by gradual reduction in the levels of malondialdehyde and stress index. we found an increased concentration of reduced glutathione and total antioxidant status and reduced levels of inflammatory markers. conclusion: weight loss improves the inflammatory state and oxidative stress levels.
Assessing albuminuria in spot morning samples from diabetic patients
Sampaio, Emerson;Delfino, Vinicius Daher Alvares;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2008, DOI: 10.1590/S0004-27302008000900012
Abstract: microalbuminuria assessment is essential for diagnosing incipient nephropathy in diabetic patients. the present study aim to evaluate whether urinary albumin concentration (uac) and urinary albumin-to-creatinine ratio (uacr) agree with 24 h urine collection in screening for albuminuria > 30 mg/24 h in type 1 and 2 diabetics. in this cross-sectional study were evaluated 293 diabetic patients (117 type 1 and 176 type 2). albuminuria was determinated by turbidimetric immunoassay. the best discriminator value was 22 mg/l (sensitivity 82.5%, specificity 74.0%) for uac and 27.3 mg/g creatinine (sensitivity 83.3%, specificity 80.9%) for uacr. areas under roc curves were 0.868 and 0.878, respectively (p = 0.53). lower discriminators as 10 mg/l (sensitivity 94.2%, specificity 48.6%) and 10 mg/g creatinine (sensitivity 96.7%, specificity 49.1%) attained high sensitivities. uac and uacr from spot morning urine had similar accuracy in screening microalbuminuria. the simplicity and lower cost of uac justifies its preferential clinical use.
An experimental model for the study of drug effects on cutaneous healing
Chiquetti Júnior, Antonio;Rodrigues, Marco Aurélio de Freitas;Delfino, Vinicius Daher Alvares;
Acta Cirurgica Brasileira , 2007, DOI: 10.1590/S0102-86502007000400014
Abstract: purpose: immunosuppressive agents are known to interfere with the healing of surgical wounds. the increasing use of these drugs warrants a better understanding of their effects on wound healing. the aim of this study was to develop an experimental model that would allow for a reliable and rapid assessment of drug effects on cutaneous wound healing. methods: thirty syngeneic lewis rats underwent surgical incision on their dorsal region, in the presence or absence of a three-week regimen of immunosuppressant drug therapy (i.e., cyclosporin, azathioprine, and prednisone). surgical site tissue was collected at intervals over 21 days after surgery and analyzed for cell number and collagen fiber content. both of these quantitative assessments were performed using digital image capture with the image pro plus 4.5 software. results: computerized histomorphometric analyses revealed an apparent inhibition of cellular responses and collagen fiber production in drug-treated animals compared to control animals. conclusion: the experimental model was reproducible, easy to perform, and allowed for quantitative histological evaluations. it may be useful for the study of surgical healing in the presence of other drug classes.
Nefropatia e retinopatia em diabéticos do tipo 1 de um programa de atendimento multiprofissional universitário
Sampaio, Emerson;Almeida, Henriqueta G.G.;Delfino, Vinicius Daher Alvares;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2007, DOI: 10.1590/S0004-27302007000300008
Abstract: type 1 diabetes mellitus (dm) is linked to micro and macrovascular long-term complications. we proposed to study the association between diabetic nephropathy (dn) and retinopathy (dr), and of these complications with clinical-laboratory variables in type 1 dm patients followed in a universitary center. it was a transversal study through medical registry analysis. we studied 81 patients; prevalence of dr was 21.0% and of dn was 35.8%, there was association between the complications. carriers of dn and dr have greater dm duration, greater hypertension prevalence, worse glycemic control and greater ldl cholesterol. it was found reduced glomerular filtration rate (gfr) in patients with microvascular complications, mainly in the ones with advanced lesions. in our study there was association between dr, nd and gfr, dm duration and hypertension were independently associated variables.
Indinavir-associated toxicity mimicking urinary tuberculosis in a patient with AIDS
Delfino, Vinicius Daher Alvares;Santiago, Natally Marques;Mocelin, Altair Jacob;Kunii, Luiz Fernando;Bortoliero, André Luiz;
Brazilian Journal of Infectious Diseases , 2008, DOI: 10.1590/S1413-86702008000100021
Abstract: this case reported to a patient with aids who presented persistent sterile leukocyturia and hematuria, lower back pain, bladder suffering symptoms, and renal papillary necrosis which were thought to be secondary to urinary tuberculosis but were demonstrated to be indinavir-associated side effects. the intention of this report is to remind medical professionals involved in the care of hiv+ patients of this possible association in order to avoid unnecessary investigation and to stress the need of careful periodical assessment of renal function and urinalysis in patients treated with indinavir.
Fun??o pulmonar e for?a muscular respiratória em pacientes com doen?a renal cr?nica submetidos à hemodiálise
Kovelis, Demetria;Pitta, Fábio;Probst, Vanessa Suziane;Peres, Celeide Pinto Aguiar;Delfino, Vinicius Daher Alvares;Mocelin, Altair Jacob;Brunetto, Ant?nio Fernando;
Jornal Brasileiro de Pneumologia , 2008, DOI: 10.1590/S1806-37132008001100004
Abstract: objective: to evaluate pulmonary function and respiratory muscle strength in chronic renal failure patients, correlating these variables with hemodialysis-related weight fluctuation; to study the correlation between the duration hemodialysis and potential respiratory alterations. methods: seventeen patients (median age, 47 years; interquartile range, 41-52 years), submitted to three weekly hemodialysis sessions for a median of 27 months (interquartile range, 14-55) were evaluated. twelve of the patients were male. the patients underwent spirometry. maximal inspiratory pressure (mip) and maximal expiratory pressure (mep) were measured prior to and after the first hemodialysis session of the week. body weight was quantified prior to and after each of the three weekly sessions. results: before the first hemodialysis session of the week, 8 patients presented mild restrictive defect, which normalized after the session in 2 of those patients. after dialysis, there was a significant increase in forced vital capacity (p = 0.02) and a significant decrease in body weight (p = 0.0001). weight fluctuation over 3 days without hemodialysis tended to correlate with the variation in forced vital capacity in the first weekly session (r = 0.47; p = 0.055). duration of hemodialysis correlated with predialysis mip (r = -0.3; p = 0.03) and mep (r = -0.63; p = 0.006). conclusions: more pronounced weight gain in the interdialytic period is associated with worsening of lung function, which is almost fully reversible by hemodialysis. in addition, longer duration of hemodialysis is associated with decreased respiratory muscle strength.
Evaluation of penicillin therapy in patients with leptospirosis and acute renal failure
DAHER, Elizabeth de Francesco;NOGUEIRA, Charlys Barbosa;
Revista do Instituto de Medicina Tropical de S?o Paulo , 2000, DOI: 10.1590/S0036-46652000000600005
Abstract: the effectiveness of specific antibiotic treatment in severe leptospirosis is still under debate. as part of a prospective study designed to evaluate renal function recovery after leptospirosis acute renal failure (arf) (arf was defined as pcr 31.5 mg/dl), the clinical evolutions of 16 treated patients (t) were compared to those of 18 untreated patients (nt). treatment or non-treatment was the option of each patient's attending infectologist. the penicillin treatment was always with 6 million iu/day for 8 days. no difference was found between the two groups in terms of age, gender, number of days from onset of symptoms to hospital admission, or results of laboratory tests performed upon admission and during hospitalization, but proteinuria was higher in the treated group. there were no significant difference in the other parameters employed to evaluate patients' clinical evolution as: length of hospital stay, days of fever, days to normalization of renal function, days to total bilirubins normalized or reached 1/3 of maximum value and days to normalization of platelet counts. dialytic treatment indication and mortality were similar between group t and nt. in conclusion, penicillin therapy did not provide better clinical outcome in patients with leptospirosis and arf.
Evaluation of penicillin therapy in patients with leptospirosis and acute renal failure
DAHER Elizabeth de Francesco,NOGUEIRA Charlys Barbosa
Revista do Instituto de Medicina Tropical de S?o Paulo , 2000,
Abstract: The effectiveness of specific antibiotic treatment in severe leptospirosis is still under debate. As part of a prospective study designed to evaluate renal function recovery after leptospirosis acute renal failure (ARF) (ARF was defined as Pcr > or = 1.5 mg/dL), the clinical evolutions of 16 treated patients (T) were compared to those of 18 untreated patients (nT). Treatment or non-treatment was the option of each patient's attending infectologist. The penicillin treatment was always with 6 million IU/day for 8 days. No difference was found between the two groups in terms of age, gender, number of days from onset of symptoms to hospital admission, or results of laboratory tests performed upon admission and during hospitalization, but proteinuria was higher in the treated group. There were no significant difference in the other parameters employed to evaluate patients' clinical evolution as: length of hospital stay, days of fever, days to normalization of renal function, days to total bilirubins normalized or reached 1/3 of maximum value and days to normalization of platelet counts. Dialytic treatment indication and mortality were similar between group T and nT. In conclusion, penicillin therapy did not provide better clinical outcome in patients with leptospirosis and ARF.
INTERVEN O PARA MODIFICAR CREN AS E ATITUDES DOS TERAPEUTAS NA MELHORA CLíNICA DOS PACIENTES COM LOMBALGIA
Bernardo Barbosa Vilar,Vinicius Cunha de Oliveira
Fisioterapia & Saúde Funcional , 2012,
Abstract: Introdu o: O efeito das interven es para modificar cren as e atitudes dos terapeutas em pacientes com dor lombar n o especifica ainda é desconhecida. Objetivo: Investigar o efeito das interven es para modificar as cren as e atitudes dos terapeutas na melhora clínica dos pacientes com dor lombar. Metodologia: Buscas realizadas nas bases de dados: MEDLINE, PsycINFO, PEDro, Cochrane e AMED e estudos clínicos aleatorizados ou quase aleatorizados investigando o efeito de interven es para modificar cren as e atitudes dos terapeutas na melhora clínica de pacientes com dor lombar foram incluídos. Qualidade dos estudos incluídos foi avaliada pela escala PEDro. Os desfechos clínicos de interesse foram dor e incapacidade. Quando houve homogeneidade suficiente, meta-análise foi realizada, e as estimativas foram reportadas com intervalo de confian a de 95% (IC95%). GRADE sumarizou a for a da recomenda o para cada desfecho analisado. Resultados: Dois artigos de baixa qualidade (PEDro<5) foram incluídos de um total de 2809 levantados através das estratégias de buscas. Meta-análise revelou very low quality evidence que a interven o n o tem efeito na incapacidade em curto prazo (tamanho de efeito de 1,8 pontos em uma escala de 100 pontos; IC95%: -7,3 a 3,7). Análises reportadas por estudos individuais também demonstraram que essas interven es n o s o eficazes na incapacidade a médio prazo (mean difference: -4,2; -13,4 a 5,0) e na dor a curto (0,0; -9,7 a 9,7), e a médio prazo (-9,1; -18,9 a 0,7). Conclus o: As interven es para modificar as cren as e atitudes dos terapeutas em rela o à melhora clínica na dor lombar n o s o efetivas. Palavras chave: Assistência ao Paciente. Conhecimentos, Atitudes e Pratica em Saúde. Dor lombar.
A clínica psicanalítica na universidade: reflex?es a partir do trabalho de supervis?o
Pinheiro, Nadja Nara Barbosa;Darriba, Vinicius Anci?es;
Psicologia Clínica , 2010, DOI: 10.1590/S0103-56652010000200004
Abstract: supported by their practice as supervisors of psychology graduating students, the authors bring up some questions related to psychoanalytical clinic at universities. two elements which fund psychoanalytical ethic are confronted: the place of knowledge and the place of subject at university and at psychoanalysis. from that, it is questioned the insertion of the students in psychoanalytic field as well as the possibilities of its transmission be made though out an experience of "control - analysis". by focusing on the effects produced by the imposition of a deadline on clinical treatment, the authors took freud's clinical directions as a paradigm of analyst's position in order to face some clinical difficulties.
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