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An In Vitro Model of the Glomerular Capillary Wall Using Electrospun Collagen Nanofibres in a Bioartificial Composite Basement Membrane
Sadie C. Slater, Vince Beachley, Thomas Hayes, Daming Zhang, Gavin I. Welsh, Moin A. Saleem, Peter W. Mathieson, Xuejun Wen, Bo Su, Simon C. Satchell
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0020802
Abstract: The filtering unit of the kidney, the glomerulus, contains capillaries whose walls function as a biological sieve, the glomerular filtration barrier. This comprises layers of two specialised cells, glomerular endothelial cells (GEnC) and podocytes, separated by a basement membrane. Glomerular filtration barrier function, and dysfunction in disease, remains incompletely understood, partly due to difficulties in studying the relevant cell types in vitro. We have addressed this by generation of unique conditionally immortalised human GEnC and podocytes. However, because the glomerular filtration barrier functions as a whole, it is necessary to develop three dimensional co-culture models to maximise the benefit of the availability of these cells. Here we have developed the first two tri-layer models of the glomerular capillary wall. The first is based on tissue culture inserts and provides evidence of cell-cell interaction via soluble mediators. In the second model the synthetic support of the tissue culture insert is replaced with a novel composite bioartificial membrane. This consists of a nanofibre membrane containing collagen I, electrospun directly onto a micro-photoelectroformed fine nickel supporting mesh. GEnC and podocytes grew in monolayers on either side of the insert support or the novel membrane to form a tri-layer model recapitulating the human glomerular capillary in vitro. These models will advance the study of both the physiology of normal glomerular filtration and of its disruption in glomerular disease.
No Relationship between Economic Freedom and Economic Growth: A Note  [PDF]
Vince Hooper
Open Journal of Business and Management (OJBM) , 2019, DOI: 10.4236/ojbm.2019.72027
Abstract: The purpose of this research note is to re-examine the link between economic freedom and economic growth because the connection has been massively over played in the past 50 years. Answering this question has important socioeconomic policy implications as economic freedom as a means of fostering higher economic growth has been high on the priority list of leading countries like the UK and US. Indeed, virtually every country in the world has embarked on this agenda of increasing economic freedom either voluntarily or at the behest of the World Bank and IMF through Washington Consensus of increasing economic freedom at all costs. The costs of liberalisation and hence increasing economic freedom have been ongoing moral hazard problems, heightened financial instability, unsustainable global debt problems, increased geopolitical risks, greater economic disequilibrium, the rise of protectionism and international social upheaval. A new economic development order needs to be constructed based on solving these issues.
A Degree-Decreasing Lemma for (M O D q- M O D p) Circuits
Vince Grolmusz
Discrete Mathematics & Theoretical Computer Science , 2001,
Abstract: Consider a (MOD q, MOD p) circuit, where the inputs of the bottom MOD p gates are degree- d polynomials with integer coefficients of the input variables (p, q are different primes). Using our main tool --- the Degree Decreasing Lemma --- we show that this circuit can be converted to a (MOD q, MOD p) circuit with linear polynomials on the input-level with the price of increasing the size of the circuit. This result has numerous consequences: for the Constant Degree Hypothesis of Barrington, Straubing and Thérien, and generalizing the lower bound results of Yan and Parberry, Krause and Waack, and Krause and Pudlák. Perhaps the most important application is an exponential lower bound for the size of (MOD q, MOD p) circuits computing the n fan-in AND, where the input of each MOD p gate at the bottom is an arbitrary integer valued function of cn variables (c<1) plus an arbitrary linear function of n input variables.
A Note on Set Systems with no Union of Cardinality 0 modulo m
Vince Grolmusz
Discrete Mathematics & Theoretical Computer Science , 2003,
Abstract: Alon, Kleitman, Lipton, Meshulam, Rabin and Spencer (Graphs. Combin. 7 (1991), no. 2, 97-99) proved, that for any hypergraph F ={F 1,F 2,…, F d(q-1)+1 }, where q is a prime-power, and d denotes the maximal degree of the hypergraph, there exists an F 0 F, such that | F∈ F 0 F| ≡ 0 (q). We give a direct, alternative proof for this theorem, and we also show that an explicit construction exists for a hypergraph of degree d and size Ω(d 2) which does not contain a non-empty sub-hypergraph with a union of size 0 modulo 6, consequently, the theorem does not generalize for non-prime-power moduli.
Astronomical station Vidojevica: In situ test of the ALTA Apogee U42 CCD camera
Vince O.
Serbian Astronomical Journal , 2012, DOI: 10.2298/saj1285065v
Abstract: Currently, the CCD camera most used by observers of the Astronomical Observatory of Belgrade is the ALTA Apogee U42. It is used for both photometric and astrometric observations. Therefore, it is very important to know different measurable parameters which describe the condition of the camera - linearity, gain, readout noise etc. In this paper, we present a thorough test of this camera.
Attenuation Laws for Galaxies with Different Star Formation Histories, Based on the SDSS Images
Vince, O.
Serbian Astronomical Journal , 2009,
Abstract: Attenuation curves (laws) in the optical part of thespectrum (from about 3500 AA~to 9000 AA) are determined for galaxieswith different star formation histories (SFHs) using images in five photometrical bands from the Sloan Digital Sky Survey (SDSS). Owing to large surveys like SDSS, it is possible to defineseveral subgroups of galaxies with similar SFHs using two spectralindices that trace SFH. Attenuation curves are analyzed in termsof SFH and compared to the curves that are often used for dustcorrection of the observed data.
Trends und Perspektiven in der Neurochirurgie: Interdisziplin res Management von Akustikusneurinomen
Vince GH
Journal für Neurologie, Neurochirurgie und Psychiatrie , 2013,
FCJ-122 Anxious Atmospheres, and the Transdisciplinary Practice of United Visual Artists
Vince Dziekan
Fibreculture Journal , 2011,
Abstract: The transformative impact of digital culture on practices associated with artistic production, curation and audience is distinctive of the continued evolution of new media arts. Through this text I propose to initiate an open exploration of the variegated term transdisciplinarity developing from the idea of it as an intersectional discourse between traditional art disciplines (Architecture, Design, Fine Art) and Electronic Media Art. Of particular interest will be extending this to an investigation of the socio-cultural experience of digital mediation, spatial practice and temporality – both as experience related to dynamic artwork as well as an influential factor in reinterpreting the aesthetic conditions associated with exhibition.In order to do so I will focus directly on London-based art and design practice United Visual Artists, or UVA. Founded in 2003, UVA's work spans architectural and responsive installations, public art, live performance and moving image.
Beyond the Museum Walls : Situating Art in Virtual Space (Polemic Overlay and Three Movements)
Vince Dziekan
Fibreculture Journal , 2005,
Abstract: In recognition of digital communication’s profound effects on social relations and institutions, this paper explores the influence of digitisation on our notions of art through the design of its institutions. No longer can the museum, as the primary technology of art, be viewed as just a physical container. With the additional of the hidden infrastructure of electronic and multimedia technologies that are to be found “behind the walls”, as it were, the architectural issues of negotiating spaces and manipulating locative settings for displaying artworks are as much virtual as physical.As a contribution to the negotiation of a distributed aesthetics, this paper entertains the possibility that transplanting art to the virtual site of the Internet disrupts our understanding of art itself. From presence on the gallery wall to the plane of the screen, if this translation offers an alternative way of seeing, then what does the Web offer to a different apperception of art? How to position the digital in the discourse surrounding art and the role it plays within contemporary cultural practice?In an attempt to ground these concerns, I will frame the subsequent discussion by focussing my attention upon one particularly representative instance: The National Gallery of Victoria’s Ian Potter Gallery of Australian Art; recognising in this localised, site-specific experience a microexample of a much more ubiquitous phenomenon.
Nico Stehr, Moral Markets: How Knowledge and Affluence Change Consumers and Products.
Vince Carducci
The Canadian Journal of Sociology , 2009,
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