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Search Results: 1 - 10 of 275 matches for " Vicky Broeckx "
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The Dark Side of EGFP: Defective Polyubiquitination
Mathijs Baens, Heidi Noels, Vicky Broeckx, Sofie Hagens, Sabine Fevery, An D. Billiau, Hugo Vankelecom, Peter Marynen
PLOS ONE , 2006, DOI: 10.1371/journal.pone.0000054
Abstract: Enhanced Green Fluorescent Protein (EGFP) is the most commonly used live cell reporter despite a number of conflicting reports that it can affect cell physiology. Thus far, the precise mechanism of GFP-associated defects remained unclear. Here we demonstrate that EGFP and EGFP fusion proteins inhibit polyubiquitination, a posttranslational modification that controls a wide variety of cellular processes, like activation of kinase signalling or protein degradation by the proteasome. As a consequence, the NF-κB and JNK signalling pathways are less responsive to activation, and the stability of the p53 tumour suppressor is enhanced in cell lines and in vivo. In view of the emerging role of polyubiquitination in the regulation of numerous cellular processes, the use of EGFP as a live cell reporter should be carefully considered.
An Objectivist Looks at the Concept of Aesthetic Value
J. L. Broeckx
Philosophica , 1985,
sthetische und soziologische Implikationen in Adornos 'Typen musikalischen Verhaltens'
J. L. Broeckx
Philosophica , 1971,
Anger and hostility in the aftermath of a wildfire disaster in Greece  [PDF]
Dimitrios Adamis, Vicky Papanikolaou
Open Journal of Psychiatry (OJPsych) , 2011, DOI: 10.4236/ojpsych.2011.12010
Abstract: Previous studies reported that anger and hostility are often presented in the victims of a disaster. This study investigates the symptoms of anger and hostility after a wildfire disaster in a rural area of Greece. Cross sectional case control study of adult population (18-65 years old). Face to face interview. Data collected were demographic, Symptom Checklist 90-Revised for assessment of hostility, type and number of losses, trust in institutions personal and social attitudes. It was found that more of the victims of the wildfires reported symptoms of hostility compared to controls but this difference was disappeared when we adjust for other variables. Risk factors for development of hostility among the victims were mistrust in military forces and media, high levels of anxiety and distress, younger age and having higher education. It was concluded that anger and hostility after a disaster perhaps are not only related to disaster but other factors concerning demographic and personal characteristics may play an important role.
Two-Part Tariff Lottery: A Means to Provide Public Good at the Social Optimum  [PDF]
Amornrat Apinunmahakul, Vicky Barham
Theoretical Economics Letters (TEL) , 2012, DOI: 10.4236/tel.2012.21006
Abstract: Pure public goods provided by charitable organizations may be provided at the first-best level when the provision is financed by an appropriately designed lottery. If lottery tickets are sold using a two-part tariff, the level of provision of the public good is greater than when fees are not charged to participate in the lottery. Unlike [13] who asymptotically approach the first-best level of provision with an arbitrarily large prize, a Pareto efficient level of the public good is produced when participation fees for the lottery are set appropriately.
Strategic Interaction and Charitable Fundraising  [PDF]
Amornrat Amornrat Apinunmahakul, Vicky Barham
Modern Economy (ME) , 2012, DOI: 10.4236/me.2012.33044
Abstract: This paper studies strategic interaction between rival charities providing multiple public goods, highlighting the role of fundraising campaigns in influencing donor decision-making. The analysis suggests that, even when charities honor donor designation, social welfare may be higher in equilibrium when charities solicit donors sequentially, rather than simultaneously or through a United Fund.
A young women with a large ovarian mass  [PDF]
Vicky O’Dwyer, Kevin Hickey
Open Journal of Obstetrics and Gynecology (OJOG) , 2013, DOI: 10.4236/ojog.2013.31008

A dermoid ovarian cyst is the commonest ovarian cystin women of reproductive age. We report a young woman who presented with a large abdominal mass. We discuss the differential diagnosis and surgical management of a large complex ovarian mass in a young woman.

Evaluation of New Commercially Available Metal Artifact Reduction (MAR) Algorithm on Both Image Quality and Relative Dosimetry for Patients with Hip Prosthesis or Dental Fillings  [PDF]
Vicky W. Huang, Kirpal Kohli
International Journal of Medical Physics,Clinical Engineering and Radiation Oncology (IJMPCERO) , 2017, DOI: 10.4236/ijmpcero.2017.62012
Abstract: Streaking artifacts on computed tomography (CT) images are caused by high density materials such as hip prosthesis, surgical clips and dental fillings. The artifacts can lead to compromised clinical outcome due to the inability to differentiate tumor volume and the uncertainties in dose calculation. The goals of our study are to evaluate how GE’s smart metal artifact reduction (MAR) algorithm impacts image quality on phantoms and dosimetry on head and neck patients with dental fillings and pelvic patients with hip prosthesis. Treatment plans calculated on the MAR and non-MAR datasets with the same beam arrangements and fluence are compared. Dose differences between the MAR and non-MAR datasets are not significant. However, substantial reductions of metal artifacts are observed when MAR algorithm is applied. Planning on the MAR dataset is recommended since it improves image quality and CT number accuracy. It also negates the need to contour the artifacts and override the density which can be time consuming.?
Reaching the Socially Isolated Person with Alzheimer's Disease Through Group Music Therapy - A Case Report
Vicky Abad
Voices: A World Forum for Music Therapy , 2002,
Abstract: The purpose of this report is to present a case on John, an 82 year old man with Alzheimer's disease, who resides in a dementia specific unit of a nursing home. People with dementia who require institutional care are often at risk of social isolation, due to the regressive nature of the disease, and the potential of developing behavioural disturbances. This case story demonstrates how group music therapy can be individually tailored to meet the needs of people with dementia who are socially isolated as a result of behavioural challenges, including aggressive and agitating behaviours, and therefore improve the quality of the person's life.
La métamorphose du célibataire chez Rachilde
Vicky Gauthier
Voix Plurielles , 2012,
Abstract: Un personnage fort intéressant fait son entrée sur la scène du roman (mais aussi de la société) à la fin du dix-neuvième siècle : le célibataire, qui devient peu à peu le héros de prédilection de la littérature fantastique. écrivant et publiant à cette époque où la misogynie est à son paroxysme, l’écrivaine fran aise Rachilde (1860-1953) semble de prime abord ne pas échapper à cette tendance : son uvre, comme la littérature décadente, verse dans l’insolite, le morbide, la folie, la névrose, la perversion ; la femme y est considérée comme l’Autre, l’ennemie de l’homme entra nant le mal et la destruction. D’ailleurs, on y retrouve fréquemment ce personnage à la Dorian Gray ou à la Des Esseintes, notamment dans Le Mordu (1889), Les Hors Nature (1897), Refaire l’Amour (1927). Plus encore, et c’est peut-être là la plus grande originalité de Rachilde, une autre figure, plus marginale et peu répandue, émerge au sein de sa fiction ; le célibataire dandy et dilettante – si cher aux décadents – est, chez elle, femme. également misanthrope désabusée – et peut-être même davantage puisqu’elle est consciente de son pouvoir et de ses possibilités d’action dans le monde dans lequel elle vit –, la femme célibataire chez Rachilde devient une force sur-naturelle et inquiétante, dont l’esprit, le corps et les traits en sont les signes prophétiques. Cet article portera sur l’étude de deux de ses romans L’Animale (1893) et La Jongleuse (1900) et s’intéressera tout particulièrement à leurs héro nes respectives, Laure et éliante, qui constituent deux profils, deux prototypes, du personnage de la femme célibataire rachildienne.
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