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Search Results: 1 - 10 of 33065 matches for " Vicent Balanzá-Martínez "
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The impact of a history of psychotic symptoms on cognitive function in euthymic bipolar patients: a comparison with schizophrenic patients and healthy controls
Brissos, Sofia;Dias, Vasco Videira;Soeiro-de-Souza, Márcio Gerhardt;Balanzá-Martínez, Vicent;Kapczinski, Flavio;
Revista Brasileira de Psiquiatria , 2011, DOI: 10.1590/S1516-44462011000400008
Abstract: background: about two-thirds of patients with bipolar disorder (bd) have a lifetime history of at least one psychotic symptom. objective: to compare the neurocognitive performance of four groups: bd patients with and without a history of psychotic symptoms (bd hps+ and bd hps-, respectively); patients with schizophrenia (sz); and healthy control (hc) subjects. method: in this cross-sectional study, 35 stabilized patients with sz, 79 euthymic (44 hps+ and 35 hps-) patients with bd, and 50 hc were administered a comprehensive battery of neuropsychological tests. results: there was worse neurocognitive functioning in both bd and sz patients compared to hc. overall, data from both groups of bd patients did not differ on sociodemographic, clinical, or neurocognitive variables. however, bd hps+ patients had significantly more negative symptoms, as measured by the positive and negative syndrome scale (panss), and showed a trend toward worse performance on executive functions compared to bd hps- patients. moreover, both bd groups had better performance on all neurocognitive tests compared to sz group. conclusions: neurocognitive dysfunction may be more marked in sz than in bd, yet qualitatively similar. a history of past psychotic symptoms in bd was not associated with more severe cognitive impairment during euthymia. therefore, bd with psychotic symptoms does not appear to be a distinct neurocognitive phenotype.
The switch from conventional to atypical antipsychotic treatment should not be based exclusively on the presence of cognitive deficits. A pilot study in individuals with schizophrenia
Gabriel Selva-Vera, Vicent Balanzá-Martínez, José Salazar-Fraile, José Sánchez-Moreno, Anabel Martinez-Aran, Patricia Correa, Eduard Vieta, Rafael Tabarés-Seisdedos
BMC Psychiatry , 2010, DOI: 10.1186/1471-244x-10-47
Abstract: In this naturalistic study, we used a comprehensive neuropsychological battery of tests to assess a sample of schizophrenia patients taking either conventional (n = 13) or novel antipsychotics (n = 26) at baseline and at two years after.Continuous antipsychotic treatment regardless of class was associated with improvement on verbal fluency, executive functions, and visual and verbal memory. Patients taking atypical antipsychotics did not show greater cognitive enhancement over two years than patients taking conventional antipsychotics.Although long-term antipsychotic treatment slightly improved cognitive function, the switch from conventional to atypical antipsychotic treatment should not be based exclusively on the presence of these cognitive deficits.Cognitive disturbances are a core feature of schizophrenia and have been extensively studied in recent years [1]. Cognitive impairment is present before the onset of the illness [2] and is also found in healthy relatives of patients, although to a lesser degree [3]. In addition, this feature is not exclusively secondary to psychiatric symptoms or medication [4]. Cognitive impairment is a better predictor of future functional outcomes compared with positive symptoms [5-7].The positive action of conventional antipsychotics drugs (APDs) on cognition is considered mild or moderate [8] and is limited to certain cognitive domains such as sustained attention [9,10].Regarding novel antipsychotics, this supposed cognitive enhancement would be mediated by their capability to raise the level of dopamine and acetylcholine in prefrontal regions [11]. However, their different affinity for brain receptors may result in different procognitive profiles of each class of antipsychotics. Many studies support a cognitive enhancement of the different atypical antipsychotics: quetiapine and olanzapine [12], quetiapine and risperidone [13], ziprasidone and olanzapine [14]; olanzapine, quetiapine, and risperidone [15], risperidone and quetiap
Filosofia e investiga o para a paz Philosophy and Peace Research Philosophie et recherche pour la paix
Vicent Martínez Guzmán
Revista Crítica de Ciências Sociais , 2012, DOI: 10.4000/rccs.1015
Abstract: Como seres humanos, temos competências para organizar as nossas rela es, fazendo uso da guerra e de qualquer outro tipo de violência estrutural, cultural ou simbólica, que suponha a marginaliza o, exclus o e morte de uns seres humanos por outros e a degrada o do ambiente. Mas também é certo que temos competências para organizar as nossas rela es de forma pacífica: exprimindo ternura ou carinho nas rela es interpessoais ou criando institui es de governa o locais, estatais ou globais que promovam rela es humanas baseadas na justi a e rela es com a natureza baseadas na sustentabilidade. Neste contexto, o desafio filosófico dos estudos para a paz é a reconstru o normativa das nossas competências para fazer as pazes. As human beings, we have skills for organizing our relationships that make use of war and other types of structural, cultural and symbolic violence that presuppose the marginalization, exclusion and death of human beings and the degradation of the environment. But we also undoubtedly have skills for organizing our relationships in a peaceful way: expressing tenderness and care in interpersonal relations or creating local, state or global institutions of governance that promote human relations based on justice, as well as relations with nature based on sustainability. In this context, the philosophical challenge of Peace Studies involves the normative reconstruction of our peacemaking skills. Comme êtres humains, nous avons des compétences pour organiser nos rapports, en recourant à la guerre et à tout autre type de violence structurale, culturelle ou symbolique, ce qui suppose la marginalisation, l’exclusion et la mort de certains êtres humains par d’autres et la dégradation du milieu. Il est cependant certain que nous disposons aussi des compétences pour organiser nos rapports de manière pacifique: en montrant de l’affection ou de la tendresse dans les relations interpersonnelles ou en créant des institutions de gestion locales, étatiques ou globales qui promeuvent des rapports humains fondés sur la justice, ainsi que des rapports avec la nature fondés sur ce qui est soutenable. Dans ce contexte, le défi philosophique des études pour la paix est la reconstruction normative de nos compétences pour faire la paix.
Políticas para la Diversidad: Hospitalidad contra Extranjería
Vicent Martínez Guzmán
Convergencia , 2003,
Abstract: En este trabajo tomaremos como punto de partida las razones que podríamos tener para no ser solidarios con los de fuera , con los que tienen culturas diferentes analizando argumento de autores como Hun ting ton y Sartori. En segundo lugar, analizaremos las tensiones en tre cultura como característica de los seres humanos y la diversidad de culturas, la aparición de la noción de extra o y extranjero, el miedo a la diferencia y, en cualquier caso, la sólida relación que se manifiesta en tre los seres humanos incluso cuando nos consideramos extra os. Defenderemos que la relación en tre los seres humanos será violenta, cuando rompa esos vínculos sólidos que constituyen la solidaridad originaria de nuestras relaciones. Finalmente recapitularemos para dar indicadores de solidaridad basados en el derecho a la hospitalidad como constitutivo de la capacidad humana de ser mo rales. La tesis será que somos inmorales si no somos hospitalarios, de ahí que necesitemos políticas para la diversidad.
Saber Hacer las Paces. Epistemologías de los Estudios para la Paz
Vicent Martínez Guzmán
Convergencia , 2000,
Abstract: En estas reflexiones se propone un giro epistemológico provocado desde la Filosofía para la Paz. Se revisa la polémica entre la explicación y comprensión en la Filosofía de las Ciencias Humanas y Sociales y como complemento a la Teoría Crítica de la ética Comunicativa se utilizan los análisis críticos postmodernos, feministas y vernaculares. Se estudia cómo estos problemas han afectado a los Estudios para la Paz y se mantiene que estos estudios al estar comprometidos con valores de paz, convulsionan las nociones mismas de conocimiento y ciencia que pretendían ser neutrales y objetivas. Finalmente se proponen las características específicas del giro epistemológico en el marco de la ética Comunicativa que se caracteriza por la participación, el compromiso con valores, la responsabilidad, el diálogo de civilizaciones, la asunción de la categoría de género y otras nociones que se dejan abiertas.
Motor speed predicts stability of cognitive deficits in both schizophrenic and bipolar I patients at one-year follow-up
J. Salazar-Fraile,V. Balanzá-Martínez,G. Selva-Vera,A. Martínez-Aran
The European Journal of Psychiatry , 2009,
Abstract: Background: We examined whether motor speed assessed by the finger tapping test predicts generalized and specific stable deficits because of a common pathogenic process in bipolar and schizophrenic patients. Methods: One hundred and two patients underwent a battery of neuropsychological tests. Patients with a score of less than one standard deviation from their siblings', sample in two assessments with an interval of one year were defined as suffering from stable deficits because of a common pathogenic process. In addition to univariate analyses, factor analyses, ordinal logistic regression, and multiple linear regressions were used. A general score was also calculated. Results: No differences were found between schizophrenic and bipolar patients in the deficits of verbal fluency, shift reasoning ability and executive attention. Schizophrenic patients had greater persistent cognitive deficit because of a common pathogenic factor in the verbal memory dimension than bipolar patients. Motor speed predicted the specific deficits of verbal fluency, shift reasoning, executive attention and the general deficit of both bipolar I and schizophrenic patients. Bipolar patients suffered a lesser specific deficit in the verbal memory dimension than schizophrenic patients did, this domain not being predicted by motor speed. Motor speed predicted the generalized deficit and the specific dimensions in which schizophrenic and bipolar patients showed no differences. Conclusions: These results suggest the presence of general and specific stable cognitive deficits because of a common pathogenic factor related to psychomotor slowness. Motor speed seems to be suitable endophenocognitype for schizophrenia and bipolar disorder.
Nuevas formas de resolución de conflictos: transformación, empoderamiento y reconocimiento
Martínez Guzmán, Vicent;París Albert, Sonia;
Revista Katálysis , 2006, DOI: 10.1590/S1414-49802006000100003
Abstract: this paper uses the scientific field of conflict studies, within the framework of peace research. it is based on a philosophic conception of the "human condition" and is guided by the notions of empowerment and recognition as tools suitable for the pacific transformation of conflicts. it also looks at the relation of the doctrine of recognition with the problem of inequality and with a political philosophy of justice. it maintains that one cannot separate policies of recognition, more closely linked to identity and culture, from policies of justice, more attent to the pacific transformation of human inequalities, poverty, indigence, marginalization and exclusion. as an example of this proposal, it uses the most recent report of the united nations human development program.
Educación para hacer las paces y la transformación pacífica de los conflictos: un análisis filosófico Educació per fer les paus i la transformació pacífica dels conflictes: una anàlisi filosòfica Peace education and the peaceful transformation of conflicts: a philosophical analysis
Sonia París Albert,Vicent Martínez Guzmán
Temps d'Educació , 2013,
Abstract: Estas reflexiones filosóficas harán una breve síntesis de la educación para hacer las paces y la transformación pacífica de los conflictos que venimos trabajando desde hace alrededor de 20 a os en nuestro Master Universitario y Doctorado Internacional en Estudios de Paz, Conflictos y Desarrollo de la Universidad Jaume I (Castellón, Espa a). La diversidad y pluralidad de nuestro estudiantado y profesorado, nos ha supuesto una concepción dinámica de las corrientes filosóficas, pedagógicas y de investigación de la paz occidentales, que se han sentido interpeladas por el sufrimiento, las prácticas y las conceptualizaciones de estudiantes y profesorado, principalmente de países empobrecidos. Con estos fundamentos estamos trabajando en un giro epistemológico que supera la dicotomía saber dominante-saberes sometidos, aplicando las teorías críticas, los estudios de postdesarrollo, postcoloniales y la perspectiva de género. Así mismo, todo ello os ha llevado a una interpretación de la transformación de los conflictos en la que la potenciación de las capacidades y el reconocimiento se convierten en ejes fundamentales. Coherents amb les idees expressades en la presentació d'aquest número, aquestes reflexions filosòfiques faran una breu síntesi de l'educació per fer les paus i la transformació pacífica dels conflictes que venim treballant vora 20 anys al nostre Màster Universitari i Doctorat Internacional en Estudis de Pau, Conflictes i Desenvolupament de la Universitat Jaume I (Castelló, Espanya). La diversitat i pluralitat del nostre alumnat i professorat ens ha suposat una concepció dinàmica dels corrents filosòfics, pedagògics i d'investigació de la pau occidentals, que s'han sentit interpel·lats, pel sofriment, les pràctiques i les conceptualitzacions d'alumnat i professorat, principalment de pa sos empobrits. Amb aquest rerefons estem treballant en un gir epistemològic que supera la dicotomia saber dominant-sabers sotmesos, aplicant les teories crítiques, els estudis de postdesenvolupament, postcolonials i la perspectiva de gènere. Així mateix ens ha dut a una interpretació de la transformació dels conflictes en què la potenciació de les capacitats i el reconeixement es converteixen en eixos fonamentals ____________________________________________________ Ces réflexions philosophiques feront une brève synthèse de l'éducation pour la paix et la transformation pacifique des conflits que nous travaillons depuis près de 20 ans dans le master universitaire et le doctorat international en études de la Paix, des Conflits et du Développement de l'Université Jaume I (C
Presentación
Vicent Martínez Guzmán,Eloísa Nos Aldás
Convergencia , 2003,
Abstract:
Magnetic Resonance Microscopy Contribution to Interpret High-Resolution Magic Angle Spinning Metabolomic Data of Human Tumor Tissue
M. Carmen Martínez-Bisbal,Vicent Esteve,Beatriz Martínez-Granados,Bernardo Celda
Journal of Biomedicine and Biotechnology , 2011, DOI: 10.1155/2011/763684
Abstract: HRMAS NMR is considered a valuable technique to obtain detailed metabolic profile of unprocessed tissues. To properly interpret the HRMAS metabolomic results, detailed information of the actual state of the sample inside the rotor is needed. MRM (Magnetic Resonance Microscopy) was applied for obtaining structural and spatially localized metabolic information of the samples inside the HRMAS rotors. The tissue was observed stuck to the rotor wall under the effect of HRMAS spinning. MRM spectroscopy showed a transference of metabolites from the tissue to the medium. The sample shape and the metabolite transfer after HRMAS indicated that tissue had undergone alterations and it can not be strictly considered as intact. This must be considered when HRMAS is used for metabolic tissue characterization, and it is expected to be highly dependent on the manipulation of the sample. The localized spectroscopic information of MRM reveals the biochemical compartmentalization on tissue samples hidden in the HRMAS spectrum.
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