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Search Results: 1 - 10 of 775 matches for " Umberto Simeoni "
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Holocene cuspate forelands in the Strait of Magellan, southern Chile
Giorgio Fontolan,Umberto Simeoni
Revista geológica de Chile , 1999,
Critical Serum Creatinine Values in Very Preterm Newborns
Alexandra Bruel, Jean-Christophe Rozé, Cyril Flamant, Umberto Simeoni, Gwena?lle Roussey-Kesler, Emma Allain-Launay
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0084892
Abstract: Background Renal failure in neonates is associated with an increased risk of mortality and morbidity. But critical values are not known. Objective To define critical values for serum creatinine levels by gestational age in preterm infants, as a predictive factor for mortality and morbidity. Study Design This was a retrospective study of all preterm infants born before 33 weeks of gestational age, hospitalized in Nantes University Hospital NICU between 2003 and 2009, with serum creatinine levels measured between postnatal days 3 to 30. Children were retrospectively randomized into either training or validation set. Critical creatinine values were defined within the training set as the 90th percentile values of highest serum creatinine (HSCr) in infants with optimal neurodevelopmental at two years of age. The relationship between these critical creatinine values and neonatal mortality, and non-optimal neural development at two years, was then assessed in the validation set. Results and Conclusion The analysis involved a total of 1,461 infants (gestational ages of 24-27 weeks (n=322), 28-29 weeks (n=336), and 30-32 weeks (803)), and 14,721 creatinine assessments. The critical values determined in the training set (n=485) were 1.6, 1.1 and 1.0 mg/dL for each gestational age group, respectively. In the validation set (n=976), a serum creatinine level above the critical value was significantly associated with neonatal mortality (Odds ratio: 8.55 (95% confidence interval: 4.23-17.28); p<0.01) after adjusting for known renal?failure risk factors, and with non-optimal neurodevelopmental outcome at two years (odds ratio: 2.06 (95% confidence interval: 1.26-3.36); p=0.004) before adjustment. Creatinine values greater than 1.6, 1.1 and 1.0 mg/dL respectively at 24-27, 28-29, 30-32 weeks of gestation were associated with mortality before and after adjustment for risk factors, and with non-optimal neurodevelopmental outcome, before adjustment.
Serravallian (Miocene) nannofossils in Patagonia, Argentina [Nannofósiles del Serravalliano (Mioceno) en Patagonia, Argentina]
Simeoni Margarita
Carnets de Géologie , 2009,
Abstract: For the first time, nannofossils found in the marine stratigraphic unit named "Patagoniano" which crops out at Cerro Chenque and Cerro Hermitte in southeastern Chubut, Argentina, are documented. They were recovered from pelitic levels in the lower part of coarsening-upward siliciclastic sedimentary sequences. The nannofossils are assigned in part to the Discoaster kugleri Zone NN7 (Martini, 1971) and CN5b (Bukry, 1971, 1973) thus allowing correlation of the productive levels with the Serravallian Stage (upper Middle Miocene).
Transition from isotropic to anisotropic beam profiles in a linear focusing channel
Wilson Simeoni Jr
Physics , 2009,
Abstract: This paper examines the transition from isotropic to anisotropic beam profiles in a linear focusing channel. Considering a high-intensity ion beam in space-charge dominated regime and large mismatched {\it RMS} beam size initially, observe a fast anisotropy situation of the beam, characterized for a transition of the transversal section round to elliptical with a coupling of transversal emittance driven for instabilities of nonlinear space-charge forces. Space-charge interactions in high-intensity linear accelerator can lead to equipartitioning of energy between the degrees of freedom. The anisotropization phenomena suggest a kind of route to equipartition. In order to understand the initial dynamical behavior of an anisotropic beam, in particular, to study possible mechanisms of equipartition connected with phase space we have to know how we can compute the variables (volume, area of surface, and area projected) that characterize the anisotropic beam in phase space. The purpose of this paper is to propose one definiton of the anisotropic equipartition \cite{Yankov1}. Anisotropic equipartition corresponds to a phase space density uniform on the surface invariant of the $\xi$, a version of the ergodic hypothesis where the $\xi$ invariant play the role of the conserved energy \cite{Kandrup3}. In the state of anisotropic equipartition, the beam temperature is stationary, the entropy grows in the cascade form, there is a coupling of transversal emittance, the beam develops an elliptical shape with a increase in its size along one direction and there is halo formation along one direction preferential.
The Intensity of IUGR-Induced Transcriptome Deregulations Is Inversely Correlated with the Onset of Organ Function in a Rat Model
Daniel Vaiman, Géraldine Gascoin-Lachambre, Farid Boubred, Fran?oise Mondon, Jean-Marc Feuerstein, Isabelle Ligi, Isabelle Grandvuillemin, Sandrine Barbaux, Eric Ghigo, Vincent Achard, Umberto Simeoni, Christophe Buffat
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0021222
Abstract: A low-protein diet applied during pregnancy in the rat results in intrauterine growth restricted (IUGR) fetuses. In humans, IUGR is associated with increased perinatal morbidity, higher incidence of neuro-developmental defects and increased risk of adult metabolic anomalies, such as diabetes and cardiovascular disease. Development and function of many organs are affected by environmental conditions such as those inducing fetal and early postnatal growth restriction. This phenomenon, termed “fetal programming” has been studied unconnectedly in some organs, but very few studies (if any) have investigated at the same time several organs, on a more comparative basis. However, it is quite probable that IUGR affects differentially most organ systems, with possible persistent changes in gene expression. In this study we address transcriptional alterations induced by IUGR in a multi-organ perspective, by systematic analysis of 20-days rat fetuses. We show that (1) expressional alterations are apparently stronger in organs functioning late in foetal or postnatal life than in organs that are functioning early (2) hierarchical classification of the deregulations put together kidney and placenta in one cluster, liver, lungs and heart in another; (3) the epigenetic machinery is set up especially in the placenta, while its alterations are rather mild in other organs; (4) the genes appear deregulated in chromosome clusters; (5) the altered expression cascades varies from organ to organ, with noticeably a very significant modification of the complement and coagulation cascades in the kidney; (6) we found a significant increase in TF binding site for HNF4 proteins specifically for liver genes that are down-regulated in IUGR, suggesting that this decrease is achieved through the action of HNF transcription factors, that are themselves transcriptionnally induced in the liver by IUGR (x 1.84 fold). Altogether, our study suggests that a combination of tissue-specific mechanisms contributes to bring about tissue-driven modifications of gene cascades. The question of these cascades being activated to adapt the organ to harsh environmental condition, or as an endpoint consequence is still raised.
Beyond Customer Churn: Generating Personalized Actions to Retain Customers in a Retail Bank by a Recommender System Approach  [PDF]
Michele Gorgoglione, Umberto Panniello
Journal of Intelligent Learning Systems and Applications (JILSA) , 2011, DOI: 10.4236/jilsa.2011.32011
Abstract: Customer churn may be a critical issue for banks. The extant literature on statistical and machine learning for customer churn focuses on the problem of correctly predicting that a customer is about to switch bank, while very rarely consid-ers the problem of generating personalized actions to improve the customer retention rate. However, these decisions are at least as critical as the correct identification of customers at risk. The decision of what actions to deliver to what customers is normally left to managers who can only rely upon their knowledge. By looking at the scientific literature on CRM and personalization, this research proposes a number of models which can be used to generate marketing ac-tions, and shows how to integrate them into a model embracing both the analytical prediction of customer churn and the generation of retention actions. The benefits and risks associated with each approach are discussed. The paper also describes a case of application of a predictive model of customer churn in a retail bank where the analysts have also generated a set of personalized actions to retain customers by using one of the approaches presented in the paper, namely by adapting a recommender system approach to the retention problem.
Numerical Study of the Injection of Carbon Dioxide in a Homogeneous Porous Media  [PDF]
Luiz Umberto Rodrigues Sica
Open Journal of Fluid Dynamics (OJFD) , 2018, DOI: 10.4236/ojfd.2018.81009
This work proposes a locally conservative and less restrictive algorithm to solve the problem dealt with in [1], i.e. a two-phase flow in a homogeneous porous medium (water and CO2), with mass absorption between the fluid phases and reaction between the CO2 phase and the rock. The latter is modeled by two non-linear hyperbolic equations that represent the transport of the flowing phases for a given velocity field (equations of saturation and concentration). From the numerical point of view, we use the operator splitting technique to properly treat the time scale of each physical phenomenon and a high-order non-oscillatory central-scheme finite volume method for nonlinear hyperbolic equations proposed by [2] that was extended for a system of equations with source terms to treat the equations that govern the saturation and concentration of phases. In addition, with respect to source terms, the mass flux between fluid phases was handled using the flash methodology, whereas kinetic theory was applied for reproducing the changes in porosity and permeability that are caused by the reaction of CO2 with the rock. The same physical trends observed in [1] were obtained in our numerical results which indicate a good predictive capability. Furthermore, this method avoids the difficulties that arise when adopting small time steps enforced by CFL stability restrictions. Finally, the results obtained show that the applicability of the KT method is beyond just a single nonlinear conservation law with the absence of source terms.
Vector Meson Exchanges and CP Asymmetry in $K^{\pm}\rightarrowπ^{\pm}π^0$
Riazuddin,N. Paver,F. Simeoni
Physics , 1993, DOI: 10.1016/0370-2693(93)90344-H
Abstract: Using a current algebra framework, we discuss the contribution of vector meson exchanges to the CP violating asymmetry in the decay $K^{\pm}\rightarrow\pi^{\pm}\pi^0$, resulting from the interference of the $K\rightarrow\pi\pi$ amplitude with the radiative correction $K\rightarrow\pi\pi\gamma$.
La Guardia di Finanza e le attività di prevenzione e repressione delle organizzazioni criminali / La Guardia di Finanza et ses activités de prévention et de répression des organisations criminelles / The Guardia di Finanza and the prevention of and fight against organized crime
Sirico Umberto
Rivista di Criminologia, Vittimologia e Sicurezza , 2010,
Abstract: The article describes the structure of Italian Guardia di Finanza and its tasks. In particular, this police force fights against economic and organized crime through specific investigation methods which are described in the text.Then, the author examines the “Molecola Project”, carried out in cooperation with the Italian Anti-Mafia Division, which consists of an operative software aimed at supporting economic and capital investigations of a high number of person involved in organized crime.
Quelques commentaires sur les personnages de fiction
Umberto Eco
SociologieS , 2010,
Abstract: L’auteur met en place des observations et développe des analyses sur le statut des personnages de fiction, mettant à contribution les ressources de l’histoire, de la littérature, de la sémiotique, de la logique et de la narratologie. De quelle vie particulière vivent les personnages de roman, qui fait que nous sommes capables de les tenir pour plus réels que des personnages réels, et que nous sommes enclins à éprouver les sentiments qu’ils éprouvent, même si nous savons qu’ils n’existent pas ? Comment ces personnages de fiction existent-ils, selon quelle partition leur existence se développe-t-elle au point d’interférer avec la n tre ? L’interrogation porte sur la nature de ce flux émotionnel qui s’écoule du lecteur vers les personnages de fiction et les investit de valeur, sur ce qui se projette de la vie vers le roman, entra nant avec lui le lecteur qui se trouve de la sorte impliqué malgré lui dans l’histoire, et se trouve pris dans le mécanisme de l’identification et de la vie fictive. Some commentaries about fiction charactersPutting into form a number of observations and developing an analysis on the status of fiction characters, the author draws on resources coming from history, literature, semiotic, logic et narration. What is that particular life lived by fiction characters that enable us to consider them as being more real than real characters, and to experience the feelings that they experience, even though we know that they do not exist? How do these characters exist? In other words, according to what “script” does their existence develop to the point of interfering with ours? The questioning centres on the nature of the emotional flux which flows from the reader towards the fictional characters thus giving them value, and on what it is which is projected from real life towards the novel and which is capable of sweeping up the reader who, without having particularly intended to do so, finds him or herself caught up in the mechanism of identifying with a fictive life. Comentarios sobre los personajes ficticiosEl autor establece un marco de observación y desarrolla los análisis sobre el papel de los personajes de ficción a partir de las aproximaciones históricas, literarias, semióticas, de la lógica y de la narración Como pueden ser construidos los personajes de novela de manera a que los consideremos como reales y que podamos experimentar sus sentimientos a sabiendas de que estos personajes no existen? Como podemos proyectarnos en personajes que no existen? El interrogante se focaliza en las caracteristicas de ese flujo emocional que pr
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