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Search Results: 1 - 10 of 489 matches for " Turgay;Celik "
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Angiotensin Receptor Blockers for the Prevention of Atrial Fibrillation Recurrences: Unending Hot Debate
Turgay Celik
Journal of Atrial Fibrillation , 2010, DOI: 10.4022/jafib.v2i2.580
Abstract: Although there is a plausible scientific basis for the notion that inhibition of the renin-angiotensin system can reduce the incidence of atrial fibrillation (AF) the greatest benefit was seen in patients with heart failure/left ventricular dysfunction in whom therapy with an angiotensin converting enzyme (ACE) inhibitor or angiotensin receptor blockers (ARBs) is probably already indicated. A number of initial studies suggested that ACE inhibitors and ARBs might prevent new onset and recurrent AF. However, the available data do not support the use of these drugs solely for the prevention of AF. I believe that additional prospective definitive trials are needed to clarify the role of ARBs in the prevention of AF recurrence.
Cold, calcium and hypertension; is there a relationship between them?
Murat Celik,Turgay Celik
Journal of Experimental and Integrative Medicine , 2011,
Abstract: In their study published in this issue of the Journal of Experimental and Integrative Medicine, Kozyreva et al touched upon a quite interesting topic; the relationship between thermoregulation and immune system under the exposure of cold, and the modulator effect of exogenous Ca(2+) in hypertensive and normotensive rats. In that study, they observed that in thermoneutral conditions, the difference between hypertensives and normo-tensives in immune response parameters was small, some calcium-dependent mechanisms of immune response development can possibly be blocked by cold, and deep cooling on the background of administered Ca(2+) caused significant stimulation instead of suppression of the immune response in rats with arterial hypertension compared to normotensives. These observations can be explained not only the functional vascular properties of blood vessels, but also other physiological systems and molecular mechanisms involving in the response to cold in hypertensives. The prevalence of hypertension is increased in people who... [J Exp Integr Med 2011; 1(4.000): 241-242]
Lifestyle Change Programs in the Management of Hyperlipidemia
Sevket Balta,Sait Demirkol,Turgay Celik
Oman Medical Journal , 2012,
Wellens' syndrome with segmental wall-motion abnormalities
Turgay Celik, Baris Bugan, Serdar Firtina, et al
Open Access Emergency Medicine , 2010, DOI: http://dx.doi.org/10.2147/OAEM.S14484
Abstract: s' syndrome with segmental wall-motion abnormalities Case report (2840) Total Article Views Authors: Turgay Celik, Baris Bugan, Serdar Firtina, et al Published Date December 2010 Volume 2010:2 Pages 87 - 89 DOI: http://dx.doi.org/10.2147/OAEM.S14484 Turgay Celik1, Baris Bugan1, Serdar Firtina1, Murat Celik2, Sait Demirkol1, Atila Iyisoy1 1Gulhane Military Medical Academy, Department of Cardiology, Ankara, Turkey; 2Van Army District Hospital, Department of Cardiology, Van, Turkey Abstract: Wellens' syndrome is a pattern of electrocardiographic T-wave changes associated with critical, proximal left anterior descending (LAD) artery stenosis. We herein report 2 cases of Wellens' syndrome with segmental wall-motion abnormalities The first case is a 50-year-old man admitted to the emergency department with typical chest pain. Admission ECG showed biphasic T waves in leads V1–V3 with inverted T waves in leads V4–V6, and cardiac enzymes were in normal limits. The second case is a 62-year-old woman admitted to the emergency department with chest pain on rest. Admission ECG showed deeply inverted T waves in leads V1–V4, and troponin T was minimally elevated. The critical lesions in the proximal segment LAD were successfully opened with stent deployments. Wall-motion abnormalities returned to normal after intervention.
P Wave Dispersion is Increased in Pulmonary Stenosis
Namik Ozmen,Bekir Sitki Cebeci,Ejder Kardesoglu,Turgay Celik
Indian Pacing and Electrophysiology Journal , 2006,
Abstract: Aim: The right atrium pressure load is increased in pulmonary stenosis (PS) that is a congenital anomaly and this changes the electrophysiological characteristics of the atria. However, there is not enough data on the issue of P wave dispersion (PWD) in PS. Methods: Forty- two patients diagnosed as having valvular PS with echocardiography and 33 completely healthy individuals as the control group were included in the study. P wave duration, p wave maximum (p max) and p minimum (p min) were calculated from resting electrocariography (ECG) obtained at the rate of 50 mm/sec. P wave dispersion was derived by subtracting p min from p max. The mean pressure gradient (MPG) at the pulmonary valve, structure of the valve and diameters of the right and left atria were measured with echocardiography. The data from two groups were compared with the Mann-Whitney U test and correlation analysis was performed with the Pearson correlation technique. Results: There wasn’t any statistically significance in the comparison of age, left atrial diameter and p min between two groups. While the MPG at the pulmonary valve was 43.11 ± 18.8 mmHg in PS patients, it was 8.4 ± 4.5 mmHg in the control group. While p max was 107.1 ± 11.5 in PS group, it was 98.2 ± 5.1 in control group (p=0.01), PWD was 40.4 ± 1.2 in PS group, and 27.2 ± 9.3 in the control group (p=0.01)Moreover, while the diameter of the right atrium in PS group was greater than that of the control group, (38.7 ± 3.9 vs 30.2 ± 2.5, p=0.02). We detected a correlation between PWD and pressure gradient in regression analysis. Conclusion: P wave dispersion and p max are increased in PS. While PWD was correlated with the pressure gradient that is the degree of narrowing, it was not correlated with the diameters of the right and left atria.
Comparative Effects of Antioxidants on Chronic Ethanol-Induced Oxidative Stress in Rat Hippocampus
Journal of Neurological Sciences , 2012,
Abstract: Objective: Long-term ethanol exposure can cause serious damages on central nervous system functions. The aim of the study was to investigate the effects of several antioxidant agents on chronic ethanol-induced oxidative stress in rat brain.Material and Methods: Oxidative stress was evaluated by measuring malondialdehyde (MDA), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), levels in the brain tissue. Ethanol was given to adult male Wistar rats by a liquid diet for 28 days. Control rats were fed by no ethanol contained izocaloric liquid diet. Melatonin (4 mg), ebselen (20 mg), proantocyanidin (PAC) (100 mg), vitamin E (100 mg) and vitamin C (100 mg) were applied to rats by oral route with gavages for 7 days from 22nd day of ethanol administration. Blood alcohol levels were measured by gas chromatography technique. MDA, SOD and GSH-Px levels were measured in hippocampal tissue.Results: While chronic exposure to ethanol caused a significant increase in MDA level, it significantly decreased both SOD and GSH-Px levels in hippocampal tissue. All antioxidants used in the study significantly reversed both the decrease in SOD and the increase in MDA levels. Vitamin E and vitamin C were ineffective on decreased GSH-Px level in ethanol administered rats.Conclusions: Our results suggest that chronic ethanol exposition causes oxidative stress responses that can be reversed by melatonin, ebselen, PAC, vitamin E and vitamin C treatments in hippocampal area of rat brain. In addition, melatonin, ebselen and PAC were more effective than vitamin E and vitamin C.
Pivotal roles of risk factors for incident atrial fibrillation in patients with newly diagnosed hyperthyroidism
Sevket Balta,Sait Demirkol,Turgay Celik,Mustafa Cakar
老年心脏病学杂志(英文版) , 2013,
Abstract: None.
High admission levels of γ-glutamyltransferase predict poor myocardial perfusion after primary percutaneous intervention
Yuksel, Uygar Cagdas;Celik, Turgay;Celik, Murat;Bugan, Baris;Iyisoy, Atila;Yaman, Halil;
Clinics , 2011, DOI: 10.1590/S1807-59322011001000010
Abstract: objective: this retrospective study aimed to investigate the relationship between admission levels of serum y-glutamyltransferase and poor myocardial perfusion after primary percutaneous coronary intervention in patients with acute myocardial infarction. introduction: reperfusion injury caused by free radical release and increased oxidative stress is responsible for the pathophysiology of the no-reflow phenomenon in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention. serum ?-glutamyltransferase is an established marker of increased oxidative stress. methods: the study population consisted of 80 patients (64 men and 16 women, mean age = 67.5 + 6.6 years) with thrombolysis in myocardial infarction 0/1 flow pre-procedurally. the patients were divided into two groups according to thrombolysis in myocardial perfusion grades that were assessed immediately following primary percutaneous coronary intervention. the two groups (group 1 and group 2) each consisted of 40 patients with thrombolysis in myocardial perfusion grades 0-1 and thrombolysis in myocardial perfusion grades 2-3, respectively. results: admission pain to balloon time, ?-glutamyltransferase and creatine kinase-mb isoenzyme levels of group 1 patients were significantly higher than those of group 2 patients. pain to balloon time, ?-glutamyltransferase, peak creatine kinase-mb isoenzyme, low left ventricular ejection fraction and poor pre-procedural thrombolysis in myocardial infarction grade were significantly associated with poor myocardial perfusion by univariate analysis. however, only pain to balloon time and ?-glutamyltransferase levels showed a significant independent association with poor myocardial perfusion by backward logistic regression analysis. adjusted odds ratios were calculated as 4.92 for pain to balloon time and 1.13 for ?-glutamyltransferase. conclusion: high admission ?-glutamyltransferase levels are associated with poor myocardial perfusion in pa
Pivotal roles of risk factors for incident atrial fibrillation in patients with newly diagnosed hyperthyroidism
The Pivotal Roles of Risk Factors for Incident Atrial Fibrillation in Patients with Newly Diagnosed Hyperthyroidism

Sevket Balt,Sait Demirkol,Turgay Celik,Mustafa Cakar,Murat Unlu,Atila Iyisoy,
Sevket Balt
,Sait Demirkol,Turgay Celik,Mustafa Cakar,Murat Unlu,Atila Iyisoy

老年心脏病学杂志(英文版) , 2013,
The Contribution of Supervisors to Doctoral Students in Doctoral Education: A Qualitative Study  [PDF]
Kazim Celik
Creative Education (CE) , 2013, DOI: 10.4236/ce.2013.41002
Abstract: In this study, it was aimed to analyze supervisor-student relationship in the doctoral education based on views of students. For this reason, research assistants having completed doctoral education and got PhD title were asked what the contributions of their supervisors were and what kind of problems they experienced in doctoral education. Considering academic advising process, it was intended to shed a light on both formal and information sides of supervisor-student relationship. As a design of the study, qualitative case study method was used. In the light of the aim of the study, “semi-structured data collection form”, one of the qualitative data collection tools, was used to collect the data. The data gained from 19 research assistants having completed their PhD degrees in the past 36 months were analyzed with content analysis. The past/ongoing contribution of supervisors to their students’ education were classified under the themes of contribution to their personal development, contribution to academic development, contribution to professional development, and contribution to intellectual development. The students, being in intimate relationship with their supervisors, emphasize positive contributions of supervisors. However, the students, not being in an intimate relationship, underline the negative characteristics of their supervisors. Few of the participants utter ongoing contribution of supervisors. This study analyzes dimensions for the contribution of supervisors to students in doctoral education, and the experiences of students in these dimensions. In this regard, academicians who are supervisors or will be supervisors are expected to benefit from the study.
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