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Search Results: 1 - 10 of 2169 matches for " Tomoko Abe "
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Negative Pressure Wound Therapy with Multiple Drainage Holes for the Treatment of Pressure Ulcer with Undermining: Case Reports  [PDF]
Hiroyuki Miura, Yumiko Ito, Tomoko Matsuda, Ayano Abe, Syun Kitaba
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2013, DOI: 10.4236/jcdsa.2013.31015
Abstract:

Noninvasive treatment of pressure ulcers with undermining is often difficult. To decrease the risk of bleeding in such conditions, negative pressure wound therapy (NPWT) has been applied. We treated a pressure ulcer with wide undermining using NPWT after opening drainage holes in the undermined area. This method can reduce the risk of bleeding and promote the rapid closure of the undermined area.

The Wheat Plastochron Mutant, fushi-darake, Shows Transformation of Reproductive Spikelet Meristem into Vegetative Shoot Meristem  [PDF]
Chikako Tahira, Naoki Shitsukawa, Yusuke Kazama, Tomoko Abe, Koji Murai
American Journal of Plant Sciences (AJPS) , 2013, DOI: 10.4236/ajps.2013.412A1005
Abstract:

In wheat plants at the vegetative growth stage, the shoot apical meristem (SAM) produces leaf primordia. When reproductive growth is initiated, the SAM forms an inflorescence meristem (IM) that differentiates a series of spikelet meristem (SM) as the branch. The SM then produces a series of floret meristem (FM) as the branch. To identify the mechanisms that regulate formation of the reproductive meristems in wheat, we have investigated a leaf initiation mutant, fushi-darake (fdk) which was developed by ion beam mutagenesis. The morphological traits were compared in wild type (WT) and fdk mutant plants grown in the experimental field. WT plants initiated leaves from SAM at regular intervals in spiral phyllotaxy, while fdk plants had 1/2 alternate phyllotaxy with rapid leaf emergence. The fdk plants have increased numbers of nodes and leaves compared with WT plants. The time interval between successive leaf initiation events (plastochron) was measured in plants grown in a growth chamber. The fdk plants clearly show the rapid leaf emergence, indicating a shortened plastochron. Each tiller in fdk plants branches at the upper part of the culm. The fine structure of organ formation in meristems of fdk plants was examined by scanning electron microscopy (SEM). The SEM analysis indicated that fdk plants show transformation of spikelet meristems into vegetative shoot meristems. In conclusion, the fdk mutant has a heterochronic nature, i.e., both

Effect of the Suppression of Cariesitic Bacterial Growth and Biofilm Formation Using Hydrogen/Free Chlorine Mixed Water Produced by an Electrolysis-Type Hydrogen Generator  [PDF]
Ryusuke Suzuki, Rin Kaneko, Masaru Nakano, Masato Kanda, Yuji Sebata, Shota Motegi, Tomoko Abe, Kazuaki Muramatsu
Health (Health) , 2019, DOI: 10.4236/health.2019.112013
Abstract: OBJECTS: Hydrogen has been shown to possess antibacterial effects at high concentrations. In addition, chlorine has a strong bactericidal effect even at low concentrations. Electrolysis is a way to simultaneously generate these two components. However, the concentration of hydrogen/free chlorine mixed water generated through electrolysis decreases quickly. It is predicted that the concentration of hydrogen/free chlorine mixed water will vary depending on the quality of water used. After investigating the optimum generation conditions, the effects of the most stable concentration of hydrogen/free chlorine mixed water on carious tooth fungus were evaluated in vitro. Thus, in this experiment, our goal was to evaluate the effects of hydrogen/free chlorine mixed water on oral bacteria. MATERIALS AND METHODS: Using a device that generates hydrogen/free chlorine through electrolysis, the differences in the concentrations of hydrogen and free chlorine based on electrolysis time were evaluated using tap water. Additionally, various concentration changes due to electrolysis time on the hydrogen/free chlorine mixed water were evaluated. Distilled tap water as a control group, hydrogen/free chlorine mixed water, and commercially available mouthwash were added for 1 minute to cultured Streptococcus mutans and then rinsed out with the culture medium. Bacterial growth (600 nm) and biofilm formation (590 nm) were measured at 3 and 6 hours after the addition of the medium. RESULTS: The concentration of hydrogen/chlorine mixed water produced by electrolysis varied depending on electrolysis time and the water used. The inhibitory effect of bacterial growth was enhanced depending on the chlorine concentration. Regarding the inhibitory effect on biofilm formation, only the mixed water of hydrogen/free chlorine concentration (500 ppb - 1.0 mg/L) had a suppressing effect after 6 hours. CONCLUSION: It was suggested that hydrogen/chlorine mixed water can be easily produced by electrolysis and has the effect of suppressing the growth of dental caries; therefore, it could be used as a cleaning agent in oral care products.
Strontium-89 Therapy for Breast Cancer Bone Metastases: Pain Relief Effects and Predictive Factors  [PDF]
Yukinori Okada, Tatsuyuki Abe, Mio Shinozaki, Shinjiro Sakaino, Hiromichi Gomi, Yasuo Nakajima, Yasuyuki Kojima, Tomoko Uejima, Koichiro Tsugawa
Advances in Breast Cancer Research (ABCR) , 2018, DOI: 10.4236/abcr.2018.74016
Abstract: In this study, we evaluate the analgesic effect of strontium-89 (Sr-89) for patients with breast cancer having multiple bone metastases and identify positive predictive factors. We retrospectively evaluated 15 patients who were administered Sr-89 for painful bone metastases from breast cancer at St. Marianna University Hospital between January 2010 and April 2014. For patients receiving multiple doses, only the first dose was evaluated. Pain relief was defined as a decrease in the score of the Numeric Rating Scale (NRS) or requirement of reduced doses of pain medication 1 - 2 months after being on Sr-89 administration. The associations between pain relief owing to Sr-89 and that owing to bone scan index, interval from bone metastasis onset to Sr-89 administration, zoledronate and denosumab treatment history, hormone therapy/aromatase inhibitor history, and chemotherapy history were assessed. A logistic model was used for statistical analysis. Pain relief was observed in 11 (73.3%) of 15 patients. No statistically significant value was observed between pain relief and bone scan index, interval from bone metastasis onset to Sr-89 administration, zoledronate and denosumab treatment history, hormone therapy/aromatase inhibitor history, and chemotherapy. Thus, Sr-89 was effective for 70% of patients with breast cancer bone metastases, although positive predictive factors for pain relief could not be determined.
Perceptual Continuity and Naturalness of Expressive Strength in Singing Voices Based on Speech Morphing
Tomoko Yonezawa,Noriko Suzuki,Shinji Abe,Kenji Mase
EURASIP Journal on Audio, Speech, and Music Processing , 2007, DOI: 10.1155/2007/23807
Abstract: This paper experimentally shows the importance of perceptual continuity of the expressive strength in vocal timbre for natural change in vocal expression. In order to synthesize various and continuous expressive strengths with vocal timbre, we investigated gradually changing expressions by applying the STRAIGHT speech morphing algorithm to singing voices. Here, a singing voice without expression is used as the base of morphing, and singing voices with three different expressions are used as the target. Through statistical analyses of perceptual evaluations, we confirmed that the proposed morphing algorithm provides perceptual continuity of vocal timbre. Our results showed the following: (i) gradual strengths in absolute evaluations, and (ii) a perceptually linear strength provided by the calculation of corrected intervals of the morph ratio by the inverse (reciprocal) function of an equation that approximates the perceptual strength. Finally, we concluded that applying continuity was highly effective for achieving perceptual naturalness, judging from the results showing that (iii) our gradual transformation method can perform well for perceived naturalness.
Perceptual Continuity and Naturalness of Expressive Strength in Singing Voices Based on Speech Morphing
Yonezawa Tomoko,Suzuki Noriko,Abe Shinji,Mase Kenji
EURASIP Journal on Audio, Speech, and Music Processing , 2007,
Abstract: This paper experimentally shows the importance of perceptual continuity of the expressive strength in vocal timbre for natural change in vocal expression. In order to synthesize various and continuous expressive strengths with vocal timbre, we investigated gradually changing expressions by applying the STRAIGHT speech morphing algorithm to singing voices. Here, a singing voice without expression is used as the base of morphing, and singing voices with three different expressions are used as the target. Through statistical analyses of perceptual evaluations, we confirmed that the proposed morphing algorithm provides perceptual continuity of vocal timbre. Our results showed the following: (i) gradual strengths in absolute evaluations, and (ii) a perceptually linear strength provided by the calculation of corrected intervals of the morph ratio by the inverse (reciprocal) function of an equation that approximates the perceptual strength. Finally, we concluded that applying continuity was highly effective for achieving perceptual naturalness, judging from the results showing that (iii) our gradual transformation method can perform well for perceived naturalness.
Results of Dating Violence Prevention Education for Japanese High School Boys  [PDF]
Tomoko Suga
Open Journal of Social Sciences (JSS) , 2017, DOI: 10.4236/jss.2017.512013
Abstract:
We conducted a class on domestic violence (DV) prevention for 234 high school boys (intervention group: 154 boys, non-intervention group: 80 boys) and verified its effect on the boys. The program dealt with respect, relationships and types of violence. The factor analysis of a questionnaire survey conducted before the class on DV prevention revealed that the high school boys’ understanding of “a relationship” and “a coercive behavior” was weak. Therefore, after conducting the class on DV prevention, we tested whether there was an improvement in their understanding of the terms “relationship” and “coercive behavior”. To understand whether boys’ understanding of “relationships” showed any change after the class, a comparison of the intervention and the non-intervention groups was carried out at four different time points—before the class on DV prevention, after the class, after a month, and after six months. A 2-factorial analysis of variance (repeated measures) was conducted. The results revealed that no mutual points of interaction were seen with the different measurement times based on the presence or absence of intervention (F (3,696) = 0.995, n.s.). To understand whether the term “coercive behaviors” changed boys’ understanding of the term after the class, the comparison from the results before the class till six months later showed significant mutual interactions with the measurement times based on the presence or absence of intervention (F (3,696) = 4.48, p < 0.01). From this study, it is clear that interventions such as a single class on DV prevention can help boys understand the term “coercive acts” and have an impact on their minds for a long time. However, the same may not be true in their understanding of “relationships”.
Japanese Educators’ Knowledge of DV  [PDF]
Tomoko Suga
Open Journal of Social Sciences (JSS) , 2018, DOI: 10.4236/jss.2018.62002
Abstract:
In the present research, a survey of the Domestic Violence (DV) related experience, knowledge, understanding of characteristics, and opinions on prevention of 244 Japanese educators was conducted. It cannot be overlooked that 8.0% of the 244 educators had experience suffering from DV. Additionally, 28.8% of the educators had experience taking a training or class on DV, and 34.0% had experience studying DV through books, etc. It was revealed from the present survey that roughly 30% of the educators had educational experience related to DV. Also it was revealed that 90.7% of female educators and 85.9% of male educators who were subjects of the present study thought that “It’s best if DV prevention is implemented during middle school and high school classes.” Educators who had studied DV through books, etc. understood six out of seven items about the characteristics of DV, which was more than those who had not studied DV. Additionally, those who had experience taking a training or class understood in detail three questions out of seven, which was more than those without experience. It is important to provide opportunities for training that would lead to learn the correct knowledge about DV for educators.
An Analysis of Surveys on Domestic Violence by Japan’s Cabinet Office (1999-2017)  [PDF]
Tomoko Suga
Open Journal of Social Sciences (JSS) , 2018, DOI: 10.4236/jss.2018.67005
Abstract: Japan’s Cabinet Office conducted surveys on DV seven times (1999, 2002, 2005, 2008, 2011, 2014, 2017). As a secondary source, we used the data on the Cabinet Offices website. In 2001, the first DV law, the Act on the Prevention of Spousal Violence was passed, after which the Japanese public began to recognize DV. Based on the question item on “domestic violence from a spouse” the data of the Cabinet Office’s survey from 2005 to 2017 indicated that on average, just over 30% of women experienced DV, while just under 20% of men did. These figures have not changed much. The proportions of victims who use advisory services have increased with every survey due to political movements and Japanese policy. In 2017, the data showed that a little less than 58% of women and almost 27% of men used advisory services. The most recent survey conducted in 2017, showed that people who do not separate from their spouse experience DV. In terms of the reasons that they do not separate, “children” weighed high on the list.
High Phosphorus Diet-Induced Changes in NaPi-IIb Phosphate Transporter Expression in the Rat Kidney: DNA Microarray Analysis
Tatsuya Suyama, Shinji Okada, Tomoko Ishijima, Kota Iida, Keiko Abe, Yuji Nakai
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0029483
Abstract: The mechanism by which phosphorus levels are maintained in the body was investigated by analyzing changes in gene expression in the rat kidney following administration of a high phosphorus (HP) diet. Male Wistar rats were divided into two groups and fed a diet containing 0.3% (control) or 1.2% (HP) phosphorous for 24 days. Phosphorous retention was not significantly increased in HP rats, but fractional excretion of phosphorus was significantly increased in the HP group compared to controls, with an excessive amount of the ingested phosphorus being passed through the body. DNA microarray analysis of kidney tissue from both groups revealed changes in gene expression profile induced by a HP diet. Among the genes that were upregulated, Gene Ontology (GO) terms related to ossification, collagen fibril organization, and inflammation and immune response were significantly enriched. In particular, there was significant upregulation of type IIb sodium-dependent phosphate transporter (NaPi-IIb) in the HP rat kidney compared to control rats. This upregulation was confirmed by in situ hybridization. Distinct signals for NaPi-IIb in both the cortex and medulla of the kidney were apparent in the HP group, while the corresponding signals were much weaker in the control group. Immunohistochemical analysis showed that NaPi-IIb localized to the basolateral side of kidney epithelial cells surrounding the urinary duct in HP rats but not in control animals. These data suggest that NaPi-IIb is upregulated in the kidney in response to the active excretion of phosphate in HP diet-fed rats.
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