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Search Results: 1 - 10 of 466065 matches for " Timothy A. Shapiro "
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Hypoglycemic myocardial stunning as cause of cardiogenic shock in a patient with ischemic cardiomyopathy: A case report and review of literature  [PDF]
Khawar Maqsood, Ghazi Mirrani, Nosheen Sarwar, Amatur R. Amarah, Muhammad Rizwan Sardar, Timothy A. Shapiro
Case Reports in Clinical Medicine (CRCM) , 2013, DOI: 10.4236/crcm.2013.21024

Hypoglycemia is a common complication seen in patients with diabetes mellitus and has been proven to have adverse effects on cardiovascular mortality. Hypoglycemia can potentially lead to worsening of cardiac function in patients with ischemic heart disease. We present a case of cardiogenic shock in a patient with hypoglycemia secondary to insulin accumulation due to worsening renal function with dramatic recovery of shock once his sugars normalized.

Recurrent takotsubo cardiomyopathy in the setting of transient neurological symptoms: a case report
Muhammad Sardar, Catherine Kuntz, Jeremy A Mazurek, Naveed Akhtar, Wajeeha Saeed, Timothy Shapiro
Journal of Medical Case Reports , 2011, DOI: 10.1186/1752-1947-5-412
Abstract: We present a rare case of a 76-year-old Caucasian woman with no history of congestive heart failure who presented to our emergency department twice with transient neurological complaints. On the first occasion, she was found to have transient aphasia which resolved within 24 hours, yet during that period she also developed symptoms of congestive heart failure and was noted to have a new, significantly depressed ejection fraction with apical akinesis and possible apical thrombus. One month after her presentation a repeat echocardiogram revealed complete resolution of all wall motion abnormalities and a return to baseline status. Seven months later she presented with ataxia, was diagnosed with vertebrobasilar insufficiency, and again developed symptoms and echocardiography findings similar to those of her first presentation. Once again, at her one-month follow-up examination, all wall motion abnormalities had completely resolved and her ejection fraction had returned to normal.Though the exact etiology of takotsubo cardiomyopathy is unclear, a neurohumoral mechanism has been proposed. Recurrence of this disorder is rare, though it has been reported in patients with structural brain abnormalities. This report is the first to describe recurrent takotsubo cardiomyopathy in a patient with transient neurological symptoms. In our patient, as expected in patients with this condition, complete resolution of all left ventricular abnormalities occurred within a short period of time. It is important for clinicians to be aware of this increasingly recognized syndrome, including its association with recurrence, especially in the clinical setting of neurologic dysfunction.Left apical ballooning syndrome, also known as takotsubo cardiomyopathy (TTC), is a clinical syndrome of transient diminished left ventricular (LV) apical wall motion with relative preservation of the basal heart segment in the presence of normal coronary arteries. It was first described in Japan in the early 1990
Landscape planning in an East Asian coastal region: the Hangzhou Bay area, China
Harvey A Shapiro,

环境科学学报(英文版) , 1999,
Abstract: The first area in China to which the McHargian approach to landscape planning was applied was the Hangzhou Bay area on the central coast. Using published maps and documents and analyzing remote sensing data, an ecological inventory (GIS) was first developed. Based on these data, several criteria for land and water use suitability evaluation were produced. These were then overlayed to evaluate the entire region for several categories of land and water uses, and a suitability synthesis map was produced. This map became the basis for developing several possible concepts and plans for the sustainable development of the region. It is a timely and much needed approach in a rapidly developing country like China if development is to fulfill both present needs and allow future generations to fulfill theirs too.
Complete transfer of populations from a single state to a pre-selected superposition of states using Piecewise Adiabatic Passage
Evgeny A. Shapiro,Valery Milner,Moshe Shapiro
Physics , 2008, DOI: 10.1103/PhysRevA.79.023422
Abstract: We develop a method for executing robust and selective transfer of populations between a single level and pre-selected superpositions of energy eigenstates. Viewed in the frequency domain, our method amounts to executing a series of simultaneous adiabatic passages into each component of the target superposition state. Viewed in {the} time domain, the method works by accumulating the wavefunction of the target wave packet as it revisits the Franck Condon region, in what amounts to an extension of the Piecewise Adiabatic Passage technique [ Shapiro et.al., Phys. Rev. Lett. 99, 033002 (2007)] to the multi-state regime. The viability of the method is verified by performing numerical tests for the Na_2 molecule.
Electromagnetically Induced Transparency Spectroscopy
Asaf Eliam,Evgeny A. Shapiro,Moshe Shapiro
Physics , 2012,
Abstract: We propose a method based on the Electromagnetically Induced Transparency (EIT) phenomenon for the detection of molecules which exist as a small minority in the presence of a majority of absorbers. The EIT effect we employ effectively eliminates the absorption of the majority species in the spectral region where it overlaps with the absorption of the minority species. The method can also be used to enhance local-modes transitions which overlap spectrally with a background of other local-modes transitions of the same molecule. The general theory is applied to the case of sparse and congested background spectra within the same molecule and to the recording of the spectra of isotopomers (of Chlorine and Methanol) that are in minority relative to other isotopomers which constitute the majority of molecules present.
Connected components in the intersection of two open opposite Schubert cells in real complete flag manifold
B. Shapiro,M. Shapiro,A. Vainshtein
Mathematics , 1997,
Abstract: In this paper we reduce the problem of counting the number of connected components in the intersection of two opposite open Schubert cells in the variety of real complete flags to a purely combinatorial question of counting the number of orbits of a certain intriguing group action in the space of upper triangular matrices with {0,1}-valued entries. The crucial step of our reduction uses the parametrization of the space of real unipotent totally positive upper triangular matrices introduced by Lusztig and Berenstein, Fomin, Zelevinski.
Periodic de Bruijn triangles: exact and asymptotic results
B. Shapiro,M. Shapiro,A. Vainshtein
Mathematics , 2003,
Abstract: We study the distribution of the number of permutations with a given periodic up-down sequence w.r.t. the last entry, find exponential generating functions and prove asymptotic formulas for this distribution.
Skew-symmetric Vanishing Lattices and Intersections of Schubert Cells
B. Shapiro,M. Shapiro,A. Vainshtein
Mathematics , 1998,
Abstract: We prove that the number of connected components in the intersection of two open opposite Schubert cells in the variety of complete real n-dimensional flags equals 3*2^{n-1} for n>5.
Mobile DNA and evolution in the 21st century
James A Shapiro
Mobile DNA , 2010, DOI: 10.1186/1759-8753-1-4
Abstract: The review assumes that readers of this journal are familiar with the actions of mobile DNA and other genome restructuring functions. It will try to integrate that familiarity into the historical development of evolutionary concepts and incorporate recent discoveries from genome sequencing. Just as our knowledge of mobile DNA has introduced new ways of thinking about hereditary change, the results of sequence analysis have documented several types of genome alterations at key places in evolutionary history, alterations which are notable because they happened within a single generation and affected multiple cellular and organismal characters at the same time: horizontal transfers of large DNA segments, cell fusions and symbioses, and whole genome doublings (WGDs). These rapid multi-character changes are fundamentally different from the slowly accumulating small random variations postulated in Darwinian and neo-Darwinian theory.Cell mergers and WGDs are the kinds of events that activate mobile DNA and genome restructuring. In order to fully integrate the genomic findings with our knowledge of mobile DNA, we have to make use of information about the molecular regulation of mobile DNA activities as well as McClintock's view that cells respond to signs of danger, frequently restructuring their genomes as part of the response [1]. This regulatory/cognitive view of genome restructuring helps us to formulate reasonable hypotheses about two unresolved questions in evolutionary theory: (i) the connections between evolutionary change and ecological disruption; and (ii) the origins of complex adaptive novelties at moments of macroevolutionary change.Since Darwin, three issues have been seen as central to formulating a coherent theory of evolutionary change:(i) descent with modification (that is the inheritance of novel characters),(ii) the origins of hereditary variation, and(iii) the operation of natural selection.All evolutionists accept descent with modification as fundament
Some Active Alternatives to Reading in Philosophy for Children
David A. Shapiro
Analytic Teaching and Philosophical Praxis , 2001,
Abstract: One of the ancillary benefits for school kids involved in doing Philosophy for Children is that it gives them an additional classroom opportunity to read. A number of teachers I’ve worked with have been initially attracted to P4C for just this reason. Even if they were initially skeptical about the value of philosophy, they at least considered it worthwhile that students were being encouragedto explore the written word. And indeed, the value of the reading aspect of P4C is not to be underestimated; anything that we can do to lure kids towards books is, I think, to be commended.Unfortunately, though, lots of kids don’t like to read, don’t read well, or just think that reading is uncool. For these reasons and others, any classroom activity - philosophy or not - that is organized primarily around explorations of textual materials is likely to leave some students by the wayside. As practitioners of Philosophy for Children, therefore, it behooves us to try to developalternative ways of raising philosophical questions, exercises that don’t rely on the written words asa starting point.In this paper, then, I discuss three different strategies I’ve developed to get (mostly) middle school students philosophizing about moral questions. These strategies use exercises - interactivelearning models - as a way to motivate discussions. Two things I need to note in describing them. First, while these examples explore issues in moral philosophy, such activities are not limited to philosophical ethics; I use similar sorts of active learning initiatives to do metaphysics, epistemology, and logic, too. Second, and more importantly, while this paper discusses active learning, I’m not suggesting that this should be the only way we do P4C. Such activities ought to be part of a comprehensive program that includes a good deal of reading and writing, as well.
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