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Search Results: 1 - 10 of 2849 matches for " Thierry Devers "
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One-pot Synthesis of TiO2 Nanoparticles in Suspensions for Quantification of Titanium Debris Release in Biological Liquids  [PDF]
Christophe Massard, Daniel Bourdeaux, Vincent Raspal, Emmanuelle Feschet-Chassot, Yves Sibaud, Eric Caudron, Thierry Devers, Kolma Oscar Awitor
Advances in Nanoparticles (ANP) , 2012, DOI: 10.4236/anp.2012.13012
Abstract: In this work we have developed an analytical method to measure potential titanium debris released from TiO2 nanotube layers devices immersed in biological fluids. This quantitative study is highly required to ensure both the security and non toxicity of the nanostructured surfaces used as future implantable medical devices in the living. A one-pot synthesis process is developed to produce high quality standard solutions of titanium dioxide nanoparticles in aqueous medium. The elaborated dispersion is then used to fabricate standard solutions in both aqueous and human blood plasma media. The synthesized nanoparticles dispersion was characterized by granulometry. The nanoparticles structure and morphology were then observed using Transmission Electron Microscopy (TEM). Thermogravimetric Analysis (TGA) was used to evaluate the concentration of TiO2 in the suspension. A quantitative routine by the use of Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES) is developed. The quantification threshold of titanium species is found to be in the 30 - 40 ppb range. None interference is detected between the particles and the human blood plasma. Using the established quantitative routine, the titanium species release from titania nanotube layers in human blood plasma is evaluated.
Association between Repeated Unpredictable Chronic Mild Stress (UCMS) Procedures with a High Fat Diet: A Model of Fluoxetine Resistance in Mice
Elsa Isingrini,Vincent Camus,Anne-Marie Le Guisquet,Maryse Pingaud,Séverine Devers,Catherine Belzung
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0010404
Abstract: Major depressive disorder is a debilitating disease. Unfortunately, treatment with antidepressants (ADs) has limited therapeutic efficacy since resistance to AD is common. Research in this field is hampered by the lack of a reliable natural animal model of AD resistance. Depression resistance is related to various factors, including the attendance of cardiovascular risk factors and past depressive episodes. We aimed to design a rodent model of depression resistance to ADs, associating cardiovascular risk factors with repeated unpredicted chronic mild stress (UCMS). Male BALB/c mice were given either a regular (4% fat) or a high fat diet (45% fat) and subjected to two 7-week periods of UCMS separated by 6 weeks. From the second week of each UCMS procedure, vehicle or fluoxetine (10 mg/kg, i.p.) was administrated daily. The effects of the UCMS and fluoxetine in both diet conditions were assessed using physical (coat state and body weight) and behavioural tests (the reward maze test and the splash test). The results demonstrate that during the second procedure, UCMS induced behavioural changes, including coat state degradation, disturbances in self-care behaviour (splash test) and anhedonia (reward maze test) and these were reversed by fluoxetine in the regular diet condition. In contrast, the high-fat diet regimen prevented the AD fluoxetine from abolishing the UCMS-induced changes. In conclusion, by associating UCMS—an already validated animal model of depression—with high-fat diet regimen, we designed a naturalistic animal model of AD resistance related to a sub-nosographic clinical entity of depression.
Hematite, Biotite and Cinnabar on the Face of the Turin Shroud: Microscopy and SEM-EDX Analysis  [PDF]
Gérard Lucotte, Thierry Derouin, Thierry Thomasset
Open Journal of Applied Sciences (OJAppS) , 2016, DOI: 10.4236/ojapps.2016.69059
Abstract: The Turin Shroud, recently accessible for hands-on scientific research, is now extensively investigated. Its pinkish red blood stains that seem anomalous ones are studied by modern techniques (notably by resolute optical microscopy and scanning electron microscopy coupled with energy dispersive X-ray). Exploration by these techniques of a blood stain located on the face permits us to discover some red-colour particles (hematite, biotite and cinnabar) of exogenous material in this stain. We finally characterize these red-colour particles and try to explain their presences in the blood stain. Globally, all these red-colour particles cannot explain all of the reddish appearance of the area under study.
Discrete Evolutionary Genetics: Multiplicative Fitnesses and the Mutation-Fitness Balance  [PDF]
Thierry Huillet, Servet Martinez
Applied Mathematics (AM) , 2011, DOI: 10.4236/am.2011.21002
Abstract: We revisit the multi-allelic mutation-fitness balance problem especially when fitnesses are multiplicative. Using ideas arising from quasi-stationary distributions, we analyze the qualitative differences between the fitness-first and mutation-first models, under various schemes of the mutation pattern. We give some stochastic domination relations between the equilibrium states resulting from these models.
Energy and Emergy Analysis to Evaluate Sustainability of Small Wastewater Treatment Plants: Application to a Constructed Wetland and a Sequencing Batch Reactor  [PDF]
Gerard Merlin, Thierry Lissolo
Journal of Water Resource and Protection (JWARP) , 2010, DOI: 10.4236/jwarp.2010.212120
Abstract: The aim of this study is to assess the sustainability of two wastewater treatment systems by energy and emergy analyses. The first system is a Sequencing Batch Reactor (SBR) which is a concrete and electricity dependent intensive process. The second is a constructed wetland, usually considered as an extensive process. The two studied facilities have similar treatment capacity and removal efficiencies. This study sheds new light on the comparison of wastewater treatment plants. We defined a new unit, the “Functional Efficiency Index” (or FEI) to describe the energetic efficiency of the facilities, expressed in kJ per year and per kg of removed COD. The energy analysis showed that, after its construction, the constructed wetland system uses only renewable energy, in marked contrast to the SBR, totally dependent on electricity which is considered here as a non renewable. The emergy analysis showed no significant differences between the two processes, but energy and emergy indices are in favour of the constructed wetland process and thus confirm its sustainability.
Improving Rwandan Criminal Justice through Forensic DNA Evidence: An Appraisal  [PDF]
Murangira B. Thierry
Beijing Law Review (BLR) , 2016, DOI: 10.4236/blr.2016.74032
Abstract: At present, the utility of forensic evidence has acquired admissibility in the area of criminal justice. This utility has been applied in various legal systems worldwide; wherein scientific evidence such as DNA helps the courts to decide complicated high-tech crime cases. Scientific evidence such as DNA is a tool used to ascertain the guilt or innocence of suspect with certainty when evidence such as blood, semen have been left at crime scene. It plays a duo role either to exonerate individual falsely accused or convict those guilty of crimes. DNA evidence is normally used to resolve criminal case in various ways. The first scenario is when the suspect is known and DNA sample collected from him/her is compared from the DNA sample collected from the scene of crime to ascertain the involvement of suspect in commission of crime. The second one is when the suspect is unknown but he/she leaves the biological evidence at the crime scene where these evidence can be analysed and compared with perpetrator’s DNA profile from DNA database to establish his/her identity. Moreover, through the use of DNA profile from database, DNA evidence collected from crime scene when the originator is unidentified be utilised to link other already committed crimes. In these circumstances, DNA technology is increasingly vital to safeguard correctness and objectivity in crime solving. Its use in Rwandan criminal justice system has not yet yielded significant impact on administration of justice. This is due to the fact that in criminal justice, forensic science in general and DNA technology in particular are still at infant stage and have not yet been introduced as subject in any law curriculum; lack of specific DNA legislation is another stumbling block wherein DNA evidence is considered as circumstantial evidence with minor consideration. It is the time wherein all actors of justice and all stakeholders (criminal justice chain and law colleges) should realize that this genetic evidence is a powerful and helpful tool for securing prosecution as well as helping to eliminate suspects early in investigation and increase prosecution rate, hence giving justice. The enactment of specific DNA legislation will guide the Investigators and Prosecutors in conducting investigation and prosecution and also the Judges in directing or evaluating DNA tests. For these reasons, DNA evidence and database need to be legally recognized through such new legislation and DNA technology be introduced in law colleges. This is one of mechanisms to break the circle of lack of awareness, admissibility of DNA
A Gravity Model Analysis for Trade between Cameroon and Twenty-Eight European Union Countries  [PDF]
Eric Doumbe Doumbe, Thierry Belinga
Open Journal of Social Sciences (JSS) , 2015, DOI: 10.4236/jss.2015.38013
Abstract: The purpose of this empirical analysis is to investigate, based on gravity model, Cameroon’s bilateral trade flows with Twenty-Eight European Union countries signatories of the EU-Cameroon Free Trade Agreement (FTA) on the 15th of January 2009. Though the said Agreement entry into force day was scheduled for the 4th of August 2014, it is important to analyze the trade trends among these 29 countries. The research findings reveal that Cameroon’s bilateral trade with European Union countries is affected positively by economic size and per capita GDP, and influenced negatively by the distance between the trading partners. The result of basic the gravity model reveals that the Product of two countries’ GDPs has positive and significant impact on bilateral trade, indeed, a 1 percent point increase in product of the GDPs leads to increase in the bilateral trade volume of Cameroon with the concerned trade partners by 1.2808 percent and about the distance factor, 1 percent point increase in distance leads to decrease the bilateral trade volume of Cameroon by 2.0306 percent.
Scanning Electron Microscopic Characterization and Elemental Analysis of One Hair Located on the Face of the Turin Shroud  [PDF]
Gérard Lucotte, Thierry Thomasset
Archaeological Discovery (AD) , 2017, DOI: 10.4236/ad.2017.51001
Abstract: As a contribution to the scientific knowledge of the Turin Shroud, we have studied by SEM-EDX a small hair fragment (14 × 9 μ) contained in a blood stain located in the Face between the two eyebrows. SEM study of this fragment shows the typical human scale hair pattern. EDX analysis of the fragment indicates that it is mainly made of organic matter, plus a little sulphur peak. The hair fragment was at both cut extremities with a razor blade formed of copper. Comparisons with present hairs of different sorts show that the hair fragment is a shaven down-hair. High-resolution SEM analysis of the pattern of residual melanosomes on the hair surface explains the blond-red colour of this hair observed in optical microscopy.
Systemic Bartonella henselae Infection in Immunocompetent Adult Presenting as Fever of Unknown Origin
Thierry Zenone
Case Reports in Medicine , 2011, DOI: 10.1155/2011/183937
Abstract: Systemic clinical presentations of infection caused by Bartonella henselae are rare in immunocompetent adults. We report four cases with hepatic and/or splenic involvement, presenting as fever of unknown origin. We discuss diagnosis and treatment of this infection. Bartonella henselae serology allows an easy diagnosis of hepatosplenic involvement in cat scratch disease, a clinical picture that appears to be underrecognized.
Habitat Selection and Mating Success in a Mustelid
Thierry Lodé
International Journal of Zoology , 2011, DOI: 10.1155/2011/159462
Abstract: Habitat selection remains a poorly understood ecological process, but relating mating behaviour to pattern of habitat selection constitutes a fundamental issue both in evolutionary ecology and in biological conservation. From radiotelemetry protocol, habitat-induced variations in mating success were investigated in a solitary mustelid carnivore, the European polecat Mustela putorius. Selection for marshy habitat was regarded as adaptive in that mating success was found greater using marches than other habitats. Males consorted with 1.3 females, revealing a low polygyny rate. Pregnant or lactating females selectively shifted to deciduous woods. That some habitat types may favour a good reproduction forms a key factor for species conservation and environmental management. Nevertheless, such as in various vertebrates, habitat requirements seem to be based on simple broad features of habitat, suggesting that habitat avoidance rather than habitat preference can explain polecat habitat predilection. 1. Introduction Adaptive significance of a behaviour is recognized when a behaviour provides a selective advantage in animal ability to adapt to its environment. Landscape structures are expected to influence especially mating behaviour and numerous species required heterogeneous habitat composition. Differences in habitat use among animals have been often ascribed to habitat selection although habitat selection remained a poorly known behavioural ecological process [1–3]. Patterns of habitat use may reveal specific choice for habitat, which should provide numerous benefits such as resource availability, shelter, avoidance of predation, and reduced interspecific competition [4, 5]. The basic conjecture in habitat selection theory is that animals select habitat features to maximize their fitness [6–9]. Thus, habitat selection is a behaviour related to fitness and differs from habitat use in which habitat preferences are mainly linked to resources. Habitat selection can lead to a strong fidelity to habitat features in which fitness was previously high [10]. Numerous species showed partitioning in microhabitat preferences, but patent demonstration for habitat selection was rare [11, 12]. Actually, natural selection can occur when distinct habitat types differ in successful breeding, and putative differences between unsuccessful and successful reproductive sites can be regarded as reflecting habitat selection [8, 12, 13]. It could be predicted that no selection occurs when unsuccessful and successful reproductive sites are not discernible from most of their main
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