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Search Results: 1 - 10 of 718741 matches for " Tatiana de P. A.; "
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Produ??o interdisciplinar de conhecimento científico no Brasil: temas ambientais
Maranh?o, Tatiana de P. A.;
Sociedade e Estado , 2010, DOI: 10.1590/S0102-69922010000300008
Abstract: a importancia dos temas ambientais parece ser compartilhada por diversos discursos políticos internacionais. apesar desse aparente consenso, países adotam estratégias diferentes de investimentos no desenvolvimento científico e tecnológico, produzido de modo desigual e concentrado. ademais, quest?es ambientais constituem objetos de pesquisa extremamente complexos, que necessitam de pesquisas interdisciplinares. no brasil, houve uma reorienta??o temática dos investimentos em p&d, o que poderia incrementar a pesquisa interdisciplinar, mas que, de fato, demonstra a dificuldade de se superar a divis?o de campos disciplinares. analisou-se que o número de grupos de pesquisa, linhas de pesquisa, pesquisadores e produ??o científica cresceu de modo significativo nos censos de 2000 a 2006. apesar desse crescimento na pesquisa, manteve-se uma concentra??o temática nos campos disciplinares: as ciências humanas e as ciências sociais aplicadas concentraram-se em pesquisas sobre meio ambiente e desenvolvimento sustentável, enquanto as biológicas, agrárias e exatas dedicaram-se majoritariamente à biodiversidade e aos recursos naturais.
One-Pot Three-Component Synthesis of N-Arylmethyl-4-(7-cyclohepta-1,3,5-trienyl)anilines  [PDF]
Lidia P. Yunnikova, Tatiana A. Akentieva, Tatiana V. Makhova
International Journal of Organic Chemistry (IJOC) , 2013, DOI: 10.4236/ijoc.2013.32017
Abstract:

We report a one-pot three-component synthesis of N-arylmethyl-4-(7-cyclohepta-1,3,5-trienyl)anilines by using various aromatic imines, tropylium tetrafluoroborate, and sodium tetrahydroborate in the presence of imidazole as activator.

Bacteriología urinaria asintomática en mujeres diabéticas tipo 2 Prevalence of asymptomatic bacteriuria in type 2 diabetic women
Tatiana Mendoza R,Manuel García de los Ríos A,Mónica Lafourcade R,Cristina Soto P
Revista médica de Chile , 2002,
Abstract: Background: Urinary tract infection (UTI) is frequent among diabetics, especially women. It may be preceded by asymptomatic bacteriuria. Aim: To study the frequency of asymptomatic bacteriuria in type 2 diabetic women. Patients and methods: Fifty women with type 2 diabetes and 50 non diabetic women were studied. In aseptic conditions, morning midstream urine specimens were obtained for microbiological analysis. The test was repeated in similar conditions during consecutive days. Urine samples were cultured in blood agar, Mac Conkey agar and CPS ID 2. Colony forming units were counted. Asymptomatic bacteriuria was defined as the presence of 100,000 or more colony forming units per ml. Leukocyturia was also quantified. Results: There was microbial growth in 40% of samples from diabetic women and 6% of samples from controls (p <0.01). Asymptomatic bacteriuria was present in 32% of diabetics and 4% of controls (p <0.01). E Coli was the most frequently isolated strain, in 55% of patients and 100% of controls. Klebsiella pneumoni was isolated in 10% of diabetics, coagulase negative Staphylococcus in 10%, Enterococcus spp in 10% and Pseudomonas aeruginosa in 5%. Leukocyturia of more than 10 cells per field, was present in 80% of diabetic women with positive culture. Women with positive cultures had a longer lasting diabetes than those with negative cultures. There was no association between urine microbiological results and glycosilated hemoglobin, fasting blood glucose, chronic complications of diabetes and treatment received. Conclusions: This study shows a high prevalence of asymptomatic bacteriuria among diabetic women (Rev Méd Chile 2002; 130: 1001-7).
Bacteriología urinaria asintomática en mujeres diabéticas tipo 2
Mendoza R,Tatiana; García de los Ríos A,Manuel; Lafourcade R,Mónica; Soto P,Cristina; Durruty A,Pilar; Alvo G,Mordo;
Revista médica de Chile , 2002, DOI: 10.4067/S0034-98872002000900006
Abstract: background: urinary tract infection (uti) is frequent among diabetics, especially women. it may be preceded by asymptomatic bacteriuria. aim: to study the frequency of asymptomatic bacteriuria in type 2 diabetic women. patients and methods: fifty women with type 2 diabetes and 50 non diabetic women were studied. in aseptic conditions, morning midstream urine specimens were obtained for microbiological analysis. the test was repeated in similar conditions during consecutive days. urine samples were cultured in blood agar, mac conkey agar and cps id 2. colony forming units were counted. asymptomatic bacteriuria was defined as the presence of 100,000 or more colony forming units per ml. leukocyturia was also quantified. results: there was microbial growth in 40% of samples from diabetic women and 6% of samples from controls (p <0.01). asymptomatic bacteriuria was present in 32% of diabetics and 4% of controls (p <0.01). e coli was the most frequently isolated strain, in 55% of patients and 100% of controls. klebsiella pneumoni? was isolated in 10% of diabetics, coagulase negative staphylococcus in 10%, enterococcus spp in 10% and pseudomonas aeruginosa in 5%. leukocyturia of more than 10 cells per field, was present in 80% of diabetic women with positive culture. women with positive cultures had a longer lasting diabetes than those with negative cultures. there was no association between urine microbiological results and glycosilated hemoglobin, fasting blood glucose, chronic complications of diabetes and treatment received. conclusions: this study shows a high prevalence of asymptomatic bacteriuria among diabetic women (rev méd chile 2002; 130: 1001-7).
Avalia??o da compostagem de carca?as de frango pelos métodos da composteira e de leiras estáticas aeradas
Paiva, Ed Carlo R.;Matos, Antonio T. de;Azevedo, M?nica A.;Barros, Renata T. P. de;Costa, Tatiana D. R.;
Engenharia Agrícola , 2012, DOI: 10.1590/S0100-69162012000500015
Abstract: it was evaluated the compostability of various waste properly mixed and the efficiency of different processes (aerated static piles and bin compost) in the elimination of microorganisms and time of composting. the experiments were built and monitored with the following compositions: bin method - coffee straw, poultry litter and poultry carcasses, asp 01 - sugar cane bagasse, poultry litter and poultry carcasses; asp 02 - sugar cane bagasse, poultry litter and ground poultry carcasses; asp 03 - coffee straw, poultry litter and ground poultry carcasses. the parameters monitored during the process, were: temperature, c/n ratio, volatile solids (vs), ph and water content, besides salmonella elimination and thermotolerants coliforms reduction were evaluated. the results obtained for the reduction of vs 20.87% (bin method), 25.31% (asp 01), 28.86% (asp 02) and 54.48% (asp 03).
Concentrations of Silver Nitrate in the In Vitro Development and Conservation of Passiflora gibertii N. E. Brown  [PDF]
Gláucia Amorim Faria, Lucas Menezes Felizardo, Antonio Flávio Arruda Ferreira, Paula Suares Rocha, Aline Namie Suzuki, Ant?nio da Silva Souza, Tatiana Góes Junghans, Maria A. P. C. Costa, Ana Patricia Bastos Peixoto, Augusto Ramalho de Morais, Beatriz Garcia Lopes, Tiago Almeida de Oliveira
American Journal of Plant Sciences (AJPS) , 2017, DOI: 10.4236/ajps.2017.812199
Abstract: The aim of this study was to evaluate the effects of silver nitrate in the in vitro development and conservation of passion fruit plants. Experiments were carried out at the Laboratory of Culture and Tissues, in the National Cassava and Fruits Research Center (EMBRAPA), using microcuttings of Passiflora gibertii N. E. Br., previously cultivated in vitro. The microcuttings were placed in MS media supplemented with silver nitrate at concentrations of 0, 1, 2, 4 and 8 mg·L-1, and, during 30, 60 and 90 days, the following variables were identified: Shooting length (cm), number of roots, number and coloration of leaves. A completely randomized design with 30 replications in a split-plot scheme was employed. Polynomial regression equations were adjusted in analysis of variance to compare averages of treatments. The obtained results support the assumption of high sensitivity of passion fruit tissues to ethylene, which reflects in the lost of vigor and in the induction of culture senescence by its accumulation. Based on obtained results, and in order to mitigate this problem, it is possible to indicate an addition of 2 mg·L-1?of silver nitrate in culture media, for the micropropagation of passion fruit plant, allowing the controlling of the atmosphere inside the culture test tubes, during the establishment of explants and other steps of the process.
Deletion of Fibroblast Growth Factor Receptor 2 from the Peri-Wolffian Duct Stroma Leads to Ureteric Induction Abnormalities and Vesicoureteral Reflux
Kenneth A. Walker, Sunder Sims-Lucas, Valeria E. Di Giovanni, Caitlin Schaefer, Whitney M. Sunseri, Tatiana Novitskaya, Mark P. de Caestecker, Feng Chen, Carlton M. Bates
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0056062
Abstract: Purpose Pax3cre-mediated deletion of fibroblast growth factor receptor 2 (Fgfr2) broadly in renal and urinary tract mesenchyme led to ureteric bud (UB) induction defects and vesicoureteral reflux (VUR), although the mechanisms were unclear. Here, we investigated whether Fgfr2 acts specifically in peri-Wolffian duct stroma (ST) to regulate UB induction and development of VUR and the mechanisms of Fgfr2 activity. Methods We conditionally deleted Fgfr2 in ST (Fgfr2ST?/?) using Tbx18cre mice. To look for ureteric bud induction defects in young embryos, we assessed length and apoptosis of common nephric ducts (CNDs). We performed 3D reconstructions and histological analyses of urinary tracts of embryos and postnatal mice and cystograms in postnatal mice to test for VUR. We performed in situ hybridization and real-time PCR in young embryos to determine mechanisms underlying UB induction defects. Results We confirmed that Fgfr2 is expressed in ST and that Fgfr2 was efficiently deleted in this tissue in Fgfr2ST?/? mice at embryonic day (E) 10.5. E11.5 Fgfr2ST?/? mice had randomized UB induction sites with approximately 1/3 arising too high and 1/3 too low from the Wolffian duct; however, apoptosis was unaltered in E12.5 mutant CNDs. While ureters were histologically normal, E15.5 Fgfr2ST?/? mice exhibit improper ureteral insertion sites into the bladder, consistent with the ureteric induction defects. While ureter and bladder histology appeared normal, postnatal day (P) 1 mutants had high rates of VUR versus controls (75% versus 3%, p = 0.001) and occasionally other defects including renal hypoplasia and duplex systems. P1 mutant mice also had improper ureteral bladder insertion sites and shortened intravesicular tunnel lengths that correlated with VUR. E10.5 Fgfr2ST?/? mice had decreases in Bmp4 mRNA in stromal tissues, suggesting a mechanism underlying the ureteric induction and VUR phenotypes. Conclusion Mutations in FGFR2 could possibly cause VUR in humans.
Variabilidade do controle glicêmico de pacientes com diabetes tipo 1 e tipo 2 durante um ano de acompanhamento
Gomes, Marília de B.;Fernandes, Luis Maurício M.P.;Fuks, Anna Gabriela;Pontes, Cristiana R.P.A.;Castro, Simone Henriques;Affonso, Filipe de Souza;Garfinkel, Tatiana;Lucas, Nélson Eduardo;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2001, DOI: 10.1590/S0004-27302001000200005
Abstract: to evaluate the variability of glicemic control in diabetic patients followed during one year, we conducted a retrospective study in which the record data of 113 diabetic patients were analyzed. the value of hba1c (glycated hemoglobin) measured during a year were registered and an index of glicemic control was calculated. this index was associated with duration of diabetes, bmi and dose of insulin. hba1c were higher in type 1 diabetes than type 2, respectively, [7.9 (4.4-13.3) vs. 7.0 (4.4-13.4)%; p= 0.007]. in 90 patients with at least two hba1c measurements, 68 (75.6%) had no change in glicemic control: 51 (76.1%) had good, 8 (11.1%) regular and 9 (11.9%) poor control. none of them sustained all the hba1c in the normal range: 26 (28.9%) had at least one normal hba1c value. in general group, 44 patients (48.9%) showed increase, 41 (45.6%) decreased and 5 (5.6%) remained with the same level of hba1c, without difference between dm1 and dm2 (p= 0,77). a difference in hba1c and diabetes duration among patients with dm2 treated with diet, oral hipoglycemic agents, combined therapy and monotherapy with insulin, was noted respectively (5.4±0.5 vs. 6.3±1.3 vs. 7.6±1.4 vs. 8.4±2.0%; p= 0.001) and (8.5±9.9 vs. 5.3±4.2 vs. 14.1±9.6 vs. 16.9±8.1 years; p= 0,003). the intraindividual coefficient of variation of hba1c was 11.6±7.4% (p= 0.0000) being 12.8±7.6 (p= 0.0000) in type 1 and 10.4±7.2% in type 2 (p= 0.0000) without difference between both groups. in conclusion: the majority of the patients in our study maintained a good control despite the intraindividual variability of hba1c and the difficulty to keeping it in the normal range.
Incidência de episódios hipot?nicos-hiporresponsivos associados à vacina combinada DTP/Hib usada no Programa Nacional de Imuniza??es
Martins, Reinaldo M.;Camacho, Luiz A. B.;Lemos, Maria Cristina F.;Noronha, Tatiana G. de;Carvalho, Maria Helena C. de;Greffe, Nadja;Silva, Marli M. da;Périssé, André R.;Maia, Maria de Lourdes S.;Homma, Akira;
Jornal de Pediatria , 2007, DOI: 10.1590/S0021-75572007000800008
Abstract: objective:to evaluate the safety of a combined diphtheria-tetanus-whole cell pertussis-haemophilus influenzae type b vaccine used on the brazilian national immunizations program, chiefly the incidence of hypotonic-hyporesponsive episodes. method: follow-up of a cohort of 21,064 infants (20,925 or 99.7% adhered to the study protocol), within 48 hours of vaccination with diphtheria-tetanus-whole cell pertussis-haemophilus influenzae type b vaccine in health care units in the city of rio de janeiro, to ascertain and investigate spontaneous and solicited severe adverse events. each child was followed-up for one dose only. results: the rate of hypotonic-hyporesponsive episodes was 1/1,744 doses (confirmed cases) and 1/1,495 doses (confirmed plus suspect cases). the rate of convulsions was 1/5,231 doses. no cases of apnea were detected. these results are comparable to those found in the literature with diphtheria-tetanus-whole cell pertussis vaccine. conclusion: the diphtheria-tetanus-whole cell pertussis-haemophilus influenzae type b vaccine under study can be safely used in the national immunizations program, according to the current precautions and contraindications.
Prevalence of common α-thalassemia determinants in south Brazil: importance for the diagnosis of microcytic anemia
Wagner, Sandrine C.;Castro, Simone M. de;Gonzalez, Tatiana P.;Santin, Ana P.;Filippon, Leticia;Zaleski, Carina F.;Azevedo, Laura A.;Amorin, Bruna;Callegari-Jacques, Sidia M.;Hutz, Mara H.;
Genetics and Molecular Biology , 2010, DOI: 10.1590/S1415-47572010005000086
Abstract: alpha thalassemia has not been systematically investigated in brazil. in this study, 493 unrelated individuals from the southernmost brazilian state of rio grande do sul were screened for deletional forms of α-thalassemia. one hundred and one individuals had microcytic anemia (mcv < 80 fl) and a normal hemoglobin pattern (hb a2 < 3.5% and hb f < 1%). the subjects were screened for -α3.7,-α4.2,-α20.5, -sea and -med deletions but only the -α3.7 allele was detected. the -α3.7 allele frequency in brazilians of european and african ancestry was 0.02 and 0.12, respectively, whereas in individuals with microcytosis the frequency was 0.20. the prevalence of α-thalassemia was significantly higher in individuals with microcytosis than in healthy individuals (p = 0.001), regardless of their ethnic origin. there were also significant differences in the hematological parameters of individuals with -α3.7/αα, -α3.7/α3.7 and β-thalassemia trait compared to healthy subjects. these data suggest that α-thalassemia is an important cause of microcytosis and mild anemia in brazilians.
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