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Search Results: 1 - 10 of 23043 matches for " Tatiana Ferreira;Garbin "
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Early HHV-6 replication is associated with morbidity non-related to CMV infection after kidney transplantation
Schroeder, Regina Barbosa;Michelon, Tatiana Ferreira;Garbin, Gabriela;Garcia, Valter;Silveira, Janaina Gomes da;Santos, Luciano;Neumann, Jorge;Keitel, Elizete;
Brazilian Journal of Infectious Diseases , 2012, DOI: 10.1590/S1413-86702012000200007
Abstract: human herpesvirus type 6-(hhv-6) has been associated with morbidity after liver transplantation. objective: the aim of this study was to determine the hhv-6 seroprevalence among donor-recipient pairs, analyze the incidence of early active infection, its clinical manifestation, interaction with cmv, and the related morbidity in the first year after kidney transplantation. methods: 46 donor-recipient pairs had igg evaluated by elisa before transplantation: hhv-6(pambio - usa) and cmv-(roche - usa). a frozen whole blood sample collected weekly (from the 1st to the 6th week) was retrospectively tested for hhv-6 viral load (vl) determination by real time quantitative pcr (qpcr, nanogen - italy). patients were preemptively surveyed for cmv by pp65 antigenemia (ag, apaap, immunohistochemistry, biotest - germany) from the 4th to the 12th week after transplantation. active infection was defined as qpcr-hhv6+ (viral-load/ml-vl) and ag+ (+cells/100.000 granulocytes), for hhv-6 and cmv, respectively. dcmv was defined as simultaneous positive antigenemia and suggestive signs/symptoms. concerning +qpcr-hhv6, associated factors, clinical manifestation, interaction with cmv and morbidity were searched. results: pre-transplant hhv-6 seroprevalence was significantly higher among kidney recipients compared to their donors (82.6x54.8%; p = 0.005 [3.9 (1.4-10.4)]). active infection by this virus occurred in 26.1% (12/46), with no association with previous igg (p = 0.412). median vl was 125 copies/ml (53-11.264), and the median ag was 21 +cells (2-740). there was no association between hhv-6 and cmv activation after transplantation (p = 0.441), neither concerning dcmv (p = 0.596). median highest ag+ and days of ganciclovir treatment were similar between qpcr-hhv6 + or - (p = 0.206 and p = 0.124, respectively). qpcr-hhv6+ was associated with higher incidence of bacterial (p = 0.009) and fungal (p = 0.001) infections, and higher number (p = 0.001) of hospital admission and longer duration
Evaluación de la incomodidad ocupacional: nivél del ruido de una clinica de graduacion
GARBIN,Artênio José Isper; GARBIN,Cléa Adas Saliba; FERREIRA,Nelly Foster; FERREIRA,Newton Luiz;
Acta Odontológica Venezolana , 2006,
Abstract: the increase of the sources producing of noise has been harming the quality of the professionals' life, accelerating to deterioration of the hearing apparel, could cause irreversible lesions, depending on the intensity of the noise and of the time of exhibition. the objective of the present study was an occupational evaluation of the noise level produced in 40 busy equipos by 80 students divided in couples, during the clinical activity, of the integrated clinic of graduation of school of dentistry of ara?atuba-unesp, and to alert the professional futures of the importance of the socket of preventive measures against the occupational diseases that you/they attack the surgeon dentist. the instrument to quantify the noise level was a dosímetro model q-400 marks quest technologies, fastened in a voluntary student. the results showed that noise level, the results showed that so much the average, maximum, and minimum (76.0 db; 83.4 db and 70.0db, respectively) it doesn't consist of an unhealthy activity according to nr-15 of safety's norm and medicine of the work and it doesn't establish the compulsory nature as for the hearing protector's use. however the maximum value was above the limited of 80 db of the norm nr-17, and finally, all the values were above 65 db of the norm nbr-10152 of acoustic comfort. it is ended that the professional should adopt measured of preventive behavior, as the use of the protector headphone, even if no obligatory, to avoid hearing lesions along his/her carreira.is important to emphasize that the universities should accomplish evaluations of unsoundness in the graduation clinics, and like this to alert the professional futures of the occupational risks, which are exposed.
Evaluación de la incomodidad ocupacional: nivél del ruido de una clinica de graduacion Avalia o do desconforto ocupacional ii: nível de ruído de uma clínica de gradua o
Artênio José Isper GARBIN,Cléa Adas Saliba GARBIN,Nelly Foster FERREIRA,Newton Luiz FERREIRA
Acta Odontológica Venezolana , 2006,
Abstract: El aumento de las fuentes productoras de ruido esta perjudicando la calidad de vida de los profesionales, acelerando el deterioro del aparato auditivo. Pudiendo causara lesiones irreparables, dependiendo la intensidad del ruido y del tiempo de exposición. El objetivo del presente estudio fue una evaluación ocupacional del nivel de ruido producido en 40 equipos utilizados por 80 alumnos divididos en duplas, en la Clínica Integrada de Graduación de la Facultad de Odontología de Ara atuba - UNESP, y alertar a los futuros profesionales de la necesidad de tomar medidas preventivas contra las enfermedades profesionales que amenazan al dentista. El instrumento para medir el nivel de ruido fue un dosímetro Modelo Q-400-Marca: Queso Technologies, equipado en un alumno voluntario. Los resultados obtenidos mostraron que el nivel de ruido, medio (76,0 dB), máximo (83,4 dB), y mínimo (70,0 dB) no representa una actividad insalubre, conforme a las Normas de Medicina del Trabajo (NR-15). Por tanto no establece la obligatoriedad de utilizar protectores auditivos. Considerando que el valor máximo fue mayor de 80 dB indicado como máximo por la Norma NR-17 y que todos los valores fueron superior a 65 dB según la Norma NBR-10152. Se concluye que el profesional debe adoptar medidas preventivas. Durante su trabajo, utilizando protector auditivo (no obligatorio), para evitar lesiones auditivas, a través de toda su carrera profesional. Cabe resaltar que las Universidades deben realizar exámenes de insalubridad en las clínicas de graduación y alertar a los futuros profesionales sobre los riesgos ocupacionales a que están expuestos. O aumento das fontes produtoras de ruído tem prejudicado a qualidade de vida dos profissionais, acelerando a deteriora o do aparelho auditivo, podendo causar les es irreversíveis, dependendo da intensidade do ruído e do tempo de exposi o. O objetivo do presente estudo foi uma avalia o ocupacional do nível de ruído produzido em 40 equipos ocupados por 80 alunos divididos em duplas, durante a atividade clínica, da Clínica Integrada de gradua o da Faculdade de Odontologia de Ara atuba UNESP, e alertar os futuros profissionais da importancia da tomada de medidas preventivas contra as doen as ocupacionais que acometem o cirurgi o dentista. O instrumento para quantificar o nível de ruído foi um dosímetro modelo Q-400 marca Quest Technologies, fixado em um aluno voluntário. Os resultados mostraram que nível de ruído, os resultados mostraram que tanto a média, máximo, e mínimo (76,0 dB; 83,4 dB e 70,0dB, respectivamente) n o consta de uma atividade insalu
Assessment of the diet of 0- to 6-year-old children in municipal schools in a Brazilian city
Garbin Clea,Arcieri R,Ferreira N,Luvizuto E
Journal of the Indian Society of Pedodontics and Preventive Dentistry , 2005,
Abstract: Diet control is one of the important factors in the prevention of dental caries because food functions as substratum for fermentation and, consequently, for the formation of the organic acids that demineralize the tooth surface. This study aims to descriptively assess school diet and the associated caries-preventive methods applied to children in all municipal nursery schools of a Brazilian city (Aragatuba/SP). For this, a questionnaire with open and closed questions was used. The results showed that all schools serve school meal, which is composed mainly of sugar, carbohydrates, and proteins. The students enjoy the meal very much because for most of them, the meal served at school is the only source of food. It was observed that 90% of the schools offer other kinds of food besides the main school meal. The snacks served such as cakes, white hominy, and milk fudge are composed of sweet and highly cariogenic foods. It was also verified that in 13.30% of the schools, the daily supervised dental hygiene, an important procedure that should not be neglected, is not carried out. This procedure introduces the children to healthy habits that are added to those acquired in the family environment. It was concluded that the school diet is potentially cariogenic and, in association with the lack of daily dental hygiene, this potential may become even higher.
Biosecurity in public and private office
Garbin, Artênio José Isper;Garbin, Cléa Adas Saliba;Arcieri, Renato Moreira;Crossato, Michel;Ferreira, Nelly Foster;
Journal of Applied Oral Science , 2005, DOI: 10.1590/S1678-77572005000200013
Abstract: biosecurity is currently a concern for all health-related services, including dentistry, since infection control has a relevant importance. in dental practice, health-related occupations have contact with a great number of individuals who are potentially capable to transmit pathogens. this study comprised a descriptive evaluation of the universal precaution measures for infection control adopted by dental practitioners working at public and private offices in the city of ara?atuba, sp. data collection was performed by a quiz with questions about individual and collective protection equipments. the results showed that the use of caps was reported by 55% of the professionals working at the public sector and 90% for the private sector. the use of masks and gloves was reported by all professionals surveyed; nevertheless, glove change between patients was not reported by 40% of professionals working at the public sector. there were more flaws in public offices as to the use of protective barriers, since except for the use of gloves, gowns and masks, the frequency of use of those barriers was smaller than at private offices.
Desafios e dificuldades do financiamento em saúde bucal: uma análise qualitativa Challenges and difficulties of financing oral health: a qualitative analysis
Suzely Adas Saliba Moimaz,Cléa Adas Saliba Garbin,Artênio José ísper Garbin,Nelly Foster Ferreira
Revista de Administra??o Pública , 2008, DOI: 10.1590/s0034-76122008000600005
Abstract: Os princípios de universalidade, integralidade e eqüidade do SUS só podem ser viabilizados com a constru o de um modelo de financiamento flexível e transparente que permita o controle social e ofere a a agilidade no uso dos recursos. Este artigo analisa as dificuldades e desafios do financiamento da saúde bucal na ótica de gestores e técnicos da área. A coleta de dados ocorreu por meio de entrevistas, queforam gravadas e transcritas para análise qualitativa, preconizada por Bardin. As dificuldades relatadas pelos entrevistados foram expressas em frases como: "Procuro cumprir a agenda, porém muita coisa n o consegui devido à falta de recursos", "n o se sabe o quanto pode gastar", "escassez de recursos para procedimentos de média e grande complexidades", "falta de recurso para troca de equipamento" e "prioridade para compra de materiais". No que tange aos desafios foi relatada a necessidade de "capacita o", "forma o" e "organiza o" dos recursos humanos em saúde pública. Observa-se a dificuldade na realiza o completa do plano previsto de gest o, assim como a necessidade de compromisso por parte dos gestores em acompanhar as etapas de todo processo de repasse financeiro e aplica o do mesmo. The principles of universality, completeness, and equity of the Unified Health System (SUS) only can be made viable with the construction of a flexible and transparent financing model that allows social control and offers agility in the use of resources. This article analyzes the difficulties and challenges of oral health financing in the perspective of managers and technicians who work in the Unique Health System. Data was collected through interviews, which were recorded and transcribed for qualitative analysis, according to Bardin's method. The difficulties reported by all interviewees were expressed by phrases such as "I try to fulfill my commitments, but I don't succeed due the lack of resources", "I don't know how much money I can spend", "scarce resources for medium and high complexity procedures", "lack of resources for replacing equipments" and "priority for purchasing materials". While discussing the challenges, the interviewees emphasized the need for "qualification", "training" and "planning" of human resources in public health. They also mentioned the difficulty in accomplishing the management plan, as in obtaining the managers' commitment in following all the stages of the transfer and application of funds.
A closer look at multiple-clone Plasmodium vivax infections: detection methods, prevalence and consequences
Havryliuk, Tatiana;Ferreira, Marcelo U;
Memórias do Instituto Oswaldo Cruz , 2009, DOI: 10.1590/S0074-02762009000100011
Abstract: the naturally occurring clonal diversity among field isolates of the major human malaria parasite plasmodium vivax remained unexplored until the early 1990s, when improved molecular methods allowed the use of blood samples obtained directly from patients, without prior in vitro culture, for genotyping purposes. here we briefly review the molecular strategies currently used to detect genetically distinct clones in patient-derived p. vivax samples, present evidence that multiple-clone p. vivax infections are commonly detected in areas with different levels of malaria transmission and discuss possible evolutionary and epidemiological consequences of the competition between genetically distinct clones in natural human infections. we suggest that, when two or more genetically distinct clones are present in the same host, intra-host competition for limited resources may select for p. vivax traits that represent major public health challenges, such as increased virulence, increased transmissibility and antimalarial drug resistance.
Impactos potenciais na avifauna decorrentes das altera??es propostas para o Código Florestal Brasileiro
Develey, Pedro Ferreira;Pongiluppi, Tatiana;
Biota Neotropica , 2010, DOI: 10.1590/S1676-06032010000400005
Abstract: proposed changes in the current brazilian forest code can lead to the reduction of native vegetation (forests, grasslands and wetlands) impacting directly many bird species. in brazil, 17 globally threatened species are dependent of riverine forests and eight of these are restricted to the brazilian territory. a decrease in the width of the area that should be protected as permanent preservation areas (área de preserva??o permanente - app) can lead to significant population losses that would put at risk the integrity of populations and, in some cases, the survival of species. in fragmented landscapes, the apps function as corridors, allowing the dispersion of birds through the matrix. legal reserve (reserva legal) areas should be maintained complementary to apps, as the avifauna composition varies in areas located near and far from water bodies. environmental heterogeneity is crucial to the maintenance of the bird community integrity. even small patches of forest are important to the avifauna, working as stepping stones that, like the corridors, enable forest birds to move across the landscape. birds are important predators, dispersers, and pollinators in agricultural ecosystems: in the tropical region, areas with high bird diversity are significantly correlated with the highest rates of arthropods' removal, including those considered pests. thus, proposed changes in the current forest code may represent a negative impact not only in relation to biodiversity, but also in regarding the agricultural production.
La problemática fractal: un punto de vista cognitivo con interés didáctico
Paradígma , 2007,
Abstract: in this article we will deepen in the problematic of the "fractal object", from a cognitive point of view and with a didactic interest. in particular, it is interesting to study what properties of the fractal are perceivable by the university students and how "they define it" having only one experience of visualization. the study includes 77 students who have previous knowledge of differential and integral calculus. the methodology is qualitative and systematic networks are used as tool for analysis of the collected qualitative data. most of the students perceive the fractal in his characteristics in a partial way and "they define it" as a mathematical set that fulfills certain properties. the previous knowledge of differential and integral calculus has not had a significant and/or determining incidence in the answers of the students
Cadeia Respiratória Mitocondrial Aspectos Clínicos, Bioquímicos, Enzimáticos e Moleculares Associados ao Dé?ce do Complexo I
Ferreira,Mariana; Aguiar,Tatiana; Vilarinho,Laura;
Arquivos de Medicina , 2008,
Abstract: mitochondrial cytopathies are a group of genetically heterogeneous disorders, that is characterized by alterations in the mitochondrial structure and oxidative phosphorylation deficiency (oxphos). oxphos system consists of five multimeric protein complexes and two electron carriers. nadh-ubiquinone oxidoreductase (complex i), the first and largest of the five complexes, is the major entry point of electrons, from krebs cycle, of the oxphos system. complex i deficiency is a frequently diagnosed defect of the mitochondrial oxphos system, caused by mutations in either the mitochondrial dna (mtdna) or the nuclear dna. because of this dual genetic control, which contributes to the complexity of the oxphos system, defects on complex i results in a broad spectrum of clinical phenotypes, that are usually associated to severe metabolic disorders of childhood, including progressive cardiomyopathy, encephalomyopathy, leukodystrophy or leigh syndrome. research on the mechanisms underlying mitochondrial complex i deficiency has used several models, such as neurospora crassa and human cell cybrids, and has taken advantage by the routinary use of novel biochemical tools, such as blue native polyacrylamide gel electrophoresis. given the complexity of this oxphos enzyme, both in structure and maintenance, it is difficult to achieve the molecular diagnosis of patients in a routine basis. in portugal, the study of these patients did not go beyond the biochemical activity measurements of respiratory chain enzymes and screening of most common point mutations and rearrangements of mtdna, until some months ago. as a consequence, at the molecular level, the majority of the complex i deficiency cases remain unsolved, being essential to move forward to a more wide-ranging study. moreover, a correct diagnosis will permit adequate genetic counselling and prenatal diagnosis.
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