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Search Results: 1 - 10 of 21645 matches for " Tapan Kumar Mondal "
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Computational Identification of Conserved microRNAs and Their Targets in Tea (Camellia sinensis)  [PDF]
Akan Das, Tapan Kumar Mondal
American Journal of Plant Sciences (AJPS) , 2010, DOI: 10.4236/ajps.2010.12010
Abstract: MicroRNAs (miRNAs) are a class of ~22 nucleotides long non coding RNA molecules which play an important role in gene regulation at the post transcriptional level. The conserved nature of miRNAs provides the basis of new miRNA identification through homology search. In an attempt to identify new conserved miRNAs in tea, previously known plant miRNAs were used for searching their homolog in a tea Expressed Sequence Tags and full length nucleotide sequence database. The sequences showing homolog no more than four mismatches were predicted for their fold back structures and passed through a series of filtration criteria, finally led us to identify 13 conserved miRNAs in tea belonging to 9 miRNA families. A total of 37 potential target genes in Arabidopsis were identified subsequently for 7 miRNA families based on their sequence complementarity which encode transcription factors (8%), enzymes (30%) and transporters (14%) as well as other proteins involved in physiological and metabolic processes (48%). Overall, our findings will accelerate the way for further researches of miRNAs and their functions in tea.
COMPUTATIONAL MODELS FOR SUSTAINABLE DEVELOPMENT
Monendra Grover,Rajesh Kumar,Tapan Kumar Mondal,S. Rajkumar
Indian Journal of Computer Science and Engineering , 2011,
Abstract: Genetic erosion is a serious problem and computational models have been developed to prevent it. The computational modeling in this field not only includes (terrestrial) reserve design, but also decision modeling for related problems such as habitat restoration, marine reserve design, and nonreserve approaches to conservation management. Models have been formulated for evaluating tradeoffs between socioeconomic, biophysical, and spatial criteria in establishing marine reserves. The percolation theory and shortest path modeling have also been used. In this article we discuss the computational models that have been developed keeping in mind the sustainable developmentConservationists estimate that alarming rate at which biological species are disappearing will have an indelible impact on humanity. Targets which were set in 2002 to reduce the biodiversity loss by 2010 have not been met. The third global diversity outlook report said that loss of wildlife and habitats could not only exacerbate climate change through rising emissions but could also have a negative impact on food sources and industry.
Effects of Supplemental Exogenous Emulsifier on Performance, Nutrient Metabolism, and Serum Lipid Profile in Broiler Chickens
Amitava Roy,Sudipto Haldar,Souvik Mondal,Tapan Kumar Ghosh
Veterinary Medicine International , 2010, DOI: 10.4061/2010/262604
Abstract: The effects of an exogenous emulsifier, glyceryl polyethylene glycol ricinoleate, on performance and carcass traits of broiler chickens were assessed. The emulsifier was added to the diet at dose rates of 0 (control), 1 (E1) and 2 (E2) % of added fat (saturated palm oil). Live weight gain (<.07) and feed conversion ratio (<.05) in 39 days were higher in the E1 dietary group. Gain: ME intake and gain: protein intake during the grower phase improved quadratically (<.05). Gross carcass traits were not affected. Body fat content and fat accretion increased (<.05) and liver fat content decreased (<.05) linearly with the level of emulsifier in diet. Fat excretion decreased (<.001) leading to increased ileal fat digestibility (<.06) in the E1 group (quadratic response). Metabolizable intake of N (<.1) and fat (<.05) increased quadratically due to supplementation of emulsifier in diet. Metabolism of trace elements and serum lipid profiles were not affected. The study revealed that supplementation of exogenous emulsifiers in diets containing moderate quantities of added vegetable fats may substantially improve broiler performance.
Evaluation of Hepatoprotective Effect of Leaves of Cassia sophera Linn.
Arijit Mondal,Sanjay Kumar Karan,Tanushree Singha,D. Rajalingam,Tapan Kumar Maity
Evidence-Based Complementary and Alternative Medicine , 2012, DOI: 10.1155/2012/436139
Abstract: In the present study, the hepatoprotective activity of ethanolic extracts of Cassia sophera Linn. leaves was evaluated against carbon-tetrachloride- (CCl4-) induced hepatic damage in rats. The extracts at doses of 200 and 400 mg/kg were administered orally once daily. The hepatoprotection was assessed in terms of reduction in histological damage, changes in serum enzymes, serum glutamate oxaloacetate transaminase (AST), serum glutamate pyruvate transaminase (ALT), serum alkaline phosphatase (ALP), total bilirubin, and total protein levels. The substantially elevated serum enzymatic levels of AST, ALT, ALP, and total bilirubin were restored towards the normalization significantly by the extracts. The decreased serum total protein level was significantly normalized. Silymarin was used as standard reference and exhibited significant hepatoprotective activity against carbon tetrachloride-induced hepatotoxicity in rats. The biochemical observations were supplemented with histopathological examination of rat liver sections. The results of this study strongly indicate that Cassia sophera leaves have potent hepatoprotective action against carbon tetrachloride-induced hepatic damage in rats. This study suggests that possible activity may be due to the presence of flavonoids in the extracts.
Adsorption of Methyl Orange onto Chitosan from Aqueous Solution  [PDF]
Tapan Kumar Saha
Journal of Water Resource and Protection (JWARP) , 2010, DOI: 10.4236/jwarp.2010.210107
Abstract: Chitosan was utilized as adsorbent to remove methyl orange (MO) from aqueous solution by adsorption. Batch experiments were conducted to study the effects of pH, initial concentration of adsorbate and temperature on dye adsorption. The kinetic data obtained from different batch experiments were analyzed using both pseudo first-order and pseudo second-order equations. The equilibrium adsorption data were analyzed by using the Freundlich and Langmuir models. The best results were achieved with the pseudo second-order kinetic model and with the Langmuir isotherm equilibrium model. The equilibrium adsorption capacity (qe) increases with increasing the initial concentration of dye and with decreasing pH. The values of qe were found to be slightly increased with increasing solution temperatures. The activation energy (Ea) of sorption kinetics was found to be 10.41 kJ/mol. Thermodynamic parameters such as change in free energy (△G), enthalpy (△H) and entropy (△S) were also discussed.
Cytohistological study of eyelid lesions and pitfalls in fine needle aspiration cytology
Mondal Santosh,Dutta Tapan
Journal of Cytology , 2008,
Abstract: Aims : The purpose of the study was to evaluate different eyelid lesions appearing as a swelling or mass, using fine needle aspiration cytology (FNAC), to conduct a cytological diagnosis of these lesions with subsequent histopathological correlation, and to identify the problems faced during microscopical examination of the smears. Materials and Methods : Fine needle aspirates from 80 eyelid swellings and histopathological correlation in 62 cases were studied. Results: Forty eight cases of benign and 32 cases of malignant lesions were diagnosed by FNAC. The five leading benign lesions were chalazions (12 cases, 15%), epithelial cysts (eight cases, 10%), chronic nonspecific inflammation (six cases, 7.5%), seborrheic keratosis (five cases, 6.25%) and benign adnexal adenoma (four cases, 5%). The most common malignant lesion was basal cell carcinoma (12 cases, 15%) followed by sebaceous gland carcinoma (nine cases, 11.25%) and squamous cell carcinoma (eight cases, 10%). Conclusions: Histopathological correlation showed that the accuracy of fine needle aspiration cytology in making diagnosis was 83.87%. Incidence of basal cell carcinoma in the study was lower, compared to most western studies. Therefore, there may be a racial and geographical variation.
Preparation and Evaluation of Rapidly Disintegrating Fast Release Tablet of Diazepam-Hydroxypropyl-β-Cyclodextrin Inclusion Complex  [PDF]
Tapan Kumar Giri, Biswanath Sa
Pharmacology & Pharmacy (PP) , 2010, DOI: 10.4236/pp.2010.11003
Abstract: This study was undertaken to develop tablets of diazepam-hydroxypropyl-β-cyclodextrin inclusion complex that disintegrate within 3 minutes and release 85% of drug within 30 minutes to provide rapid action of the drug through oro-mucosal route. Formation of inclusion complex was verified using X-ray diffraction and differential scanning calorimetric studies. Enhanced of aqueous solubility, as evident from phase solubility study, and dissolution of the drug were related with the formation of inclusion complex. Among the various formulations, tablet containing inclusion complex of drug/hydroxypropyl-β-cyclodextrin in a molar ratio of 1:2, and a combination of microcrystalline cellulose/lactose in a ratio of 4:1 disintegrated in 13 seconds and released 85% drug within 9 minutes. Addition of 10% w/w polyvinyl pyrrolidone in the tablet formulation further enhanced the drug release. Accelerated stability study indicated that mean dissolution time of the drug from the tablet did not change significantly within 6 months.
Effect of Nano Size TiO2 Particles on Mechanical Properties of AWS E 11018M Type Electrode  [PDF]
Tapan Kumar Pal, Utpal Kumar Maity
Materials Sciences and Applications (MSA) , 2011, DOI: 10.4236/msa.2011.29173
Abstract: Addition of nano size particles of TiO2 in the coating of shielded metal arc welding electrode (E 11018M) partially substituting the conventional micro size TiO2 was studied for possible enhanced electrode characteristics. The results show that the nano size particle of TiO2 improved recovery of elements such as Mn, Ni, Mo, Ti etc. as well as increased all-weld-metal tensile and charpy impact properties at –51℃. Furthermore, the charpy impact properties were found to be very sensitive to variations in Ti content of the weld deposit.
An in Vitro Approach for the Conservation of Meizotropis pellita: An Endangered and Endemic Plant  [PDF]
Lalit Singh, Tapan Kumar Nailwal, Lalit Tewari
American Journal of Plant Sciences (AJPS) , 2013, DOI: 10.4236/ajps.2013.46151
Abstract:

An efficient protocol for high frequency in vitro regeneration of Meizotropis pellita an endangered and endemic plant was developed. In vitro germination of the seeds of Patwa was achieved successfully after incubation for 10 -15 days and plantlets up to a height of 5 -7 cm with profuse rooting were observed after incubation for 7 weeks in hormone free MS medium. This in vitro germination totally reduced contamination that used to occur in the explant taken from the field. Callus induction and proliferation were observed in leaf explants after 15 -20 days of incubation in MS medium containing 2 -4, D (9.06 μM) alone or in combination with 2 -4, D (9.06 μM) + 2-iP (7.38 μM). Shoot regeneration was achieved from 2 months old callus explant in MS

Kinetics, Isotherm and Thermodynamic Studies of the Adsorption of Reactive Red 239 Dye from Aqueous Solution by Chitosan 8B  [PDF]
Subarna Karmaker, Farin Sintaha, Tapan Kumar Saha
Advances in Biological Chemistry (ABC) , 2019, DOI: 10.4236/abc.2019.91001
Abstract: The adsorption of reactive red 239 (RR239) dye onto chitosan 8B was studied in aqueous solution at various pHs, initial dye concentrations, ionic strengths and temperatures, respectively. The adsorption of dye onto chitosan 8B was confirmed by diffuse reflectance electronic absorption spectra. The adsorption of RR239 onto chitosan 8B was greatly influenced by solution pHs, initial dye concentrations, ionic strengths and temperatures. The kinetics and mechanism of dye adsorption process were analyzed by pseudo first-, second-order, Elovich and intraparticle diffusion kinetic models. The adsorption kinetics of RR239 dye followed a pseudo second-order model very well. The surface sorption and intraparticle diffusion mechanisms were involved in the actual sorption process. The equilibrium isotherm data were fitted well with the Langmuir model rather than the Freundlich, Temkin and Dubinin-Radushkevich models. The maximum dye adsorption onto chitosan 8B was estimated to be 163.93 μmol/g at 45°C. The activation energy (Ea) was obtained to be 23.30 kJ/mol. The computed thermodynamic parameters such as ΔG\"\", ΔH\"\", ΔS\"\", ΔG, ΔH and ΔS confirmed that the adsorption of RR239 dye onto chitosan 8B was a spontaneous endothermic physisorption process. Desorption test was carried out in NaOH solution (pH 12.5) and the chitosan flakes could be reused.
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