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Scrotal Skin Metastases of Renal Cell Carcinoma: A Case Report  [PDF]
Khadija Benhayoune, Hinde El Fatemi, Jamal El Fassi, Soufiane Mellas, Laila Chbani, Nawal Hammas, Taoufiq Harmouch, Hassan Farih
Case Reports in Clinical Medicine (CRCM) , 2015, DOI: 10.4236/crcm.2015.43020
Cutaneous metastasis from renal cell carcinoma is believed to be rare. We present a 66-year-old man operated for kidney cancer 20 years ago and has consulted for a scrotal lesion that had started 20 days. The physical examination revealed an erythematous lesion. A biopsy of the scrotal skin was made. We found a scrotal metastasis of renal cell carcinoma.
Post Traumatic Diaphragmatic Hernia Revealing a Colonic Tumor  [PDF]
Mohammed Elkehal, Sani Rabiou, Boubacar Efared, Saad Slaiki, Hicham Elbouhadouti, Yassine Ouadnouni, Nawal Hammas, Taoufiq Harmouch, Mohamed Smahi
Open Journal of Thoracic Surgery (OJTS) , 2016, DOI: 10.4236/ojts.2016.63003
Abstract: Post traumatic diaphragmatic injuries have long been known. However their varied clinical, expressions lead to difficulties which cause its delay. The occurrence of herniation of hollow viscera in the thoracic cavity followed by its necrosis or perforation, is a delayed complication, a rare entity with a poor prognosis. The discovery of a colonic tumor in a diaphragmatic hernia is an exceptional clinical circumstance. Here we report the case of a patient with a complicated diaphragmatic hernia, whose symptoms are precipitated by the presence of a colon stenosing tumor. The management consisted of an exclusive laparotomy had allowed dealing in one surgical intervention with both the abdominal and thoracic injuries.
Solitary Granular Cell Tumor of Cecum: A Case Report
Kaoutar Znati,Taoufiq Harmouch,Amal Benlemlih,Hinde Elfatemi
ISRN Gastroenterology , 2011, DOI: 10.5402/2011/943804
Hepatobiliary Cystadenoma Revealed by a Jaundice: A Case Report
Taoufiq Harmouch,Marie-pierre Vullierme,Alain Sauvanet,Valérie Paradis,Affaf Amarti
Case Reports in Gastrointestinal Medicine , 2011, DOI: 10.1155/2011/895605
Abstract: Introduction. Hepatobiliary cystadenomas are rare benign cystic tumors and have a potential for recurrence and malignant transformation. The diagnosis may be very difficult because of absence of typical imaging feature in some cases. Case Presentation. In this paper, the authors discuss a 57-year-old woman who presented a jaundice related to hepatobiliary cystadenoma. Biological and radiological examinations have led to surgery, and the diagnosis is made after a histological examination of surgical specimens. Conclusion. This observation illustrates a hepatobiliary cystadenoma revealed by jaundice. Histology examination contributed to diagnosis. The authors discussed the mechanisms of biliary obstruction and differential diagnoses through a review of the literature.
Can p63 serve as a biomarker for giant cell tumor of bone? A Moroccan experience
Nawal Hammas, Chbani Laila, Alaoui Lamrani Youssef, El Hind, Taoufiq Harmouch, Tizniti Siham, Amarti Afaf
Diagnostic Pathology , 2012, DOI: 10.1186/1746-1596-7-130
Abstract: This study includes 48 giant cell-containing tumors and pseudotumors of bone. P63 expression was evaluated by immunohistochemistry. Data analysis was performed using Epi-info software and SPSS software package (version 17).Immunohistochemical analysis showed a P63 nuclear expression in all giant cell tumors of bone, in 50% of osteoid osteomas, 40% of aneurysmal bone cysts, 37.5% of osteoblastomas, 33.3% of chondromyxoide fibromas, 25% of non ossifiant fibromas and 8.3% of osteosarcomas. Only one case of chondroblastoma was included in this series and expressed p63. No P63 immunoreactivity was detected in any of the cases of central giant cell granulomas or langerhans cells histiocytosis. The sensitivity and negative predictive value (NPV) of P63 immunohistochemistry for the diagnosis of giant cell tumor of bone were 100%. The specificity and positive predictive value (PPV) were 74.42% and 59.26% respectively.This study found not only that GCTOB expresses the P63 but it also shows that this protein may serve as a biomarker for the differential diagnosis between two morphologically similar lesions particularly in instances of limited sampling. Indeed, P63 expression seems to differentiate between giant cell tumor of bone and central giant cell granuloma since the latter does not express P63. Other benign and malignant giant cell-containing lesions express P63, decreasing its specificity as a diagnostic marker, but a strong staining was seen, except a case of chondroblastoma, only in giant cell tumor of bone. Clinical and radiological confrontation remains essential for an accurate diagnosis.The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1838562590777252 webcite.Giant cell tumour of bone (GCTOB) is the prototype of giant cell rich neoplasms of the skeleton. The term giant cell tumour was coined by Bloodgood in 1912 [1] and it was not until 1940 that Jaffe distinguished giant cell tumour of bone from other bone tum
A giant peritoneal simple mesothelial cyst: a case report
Abdelmalek Ousadden, Hicham Elbouhaddouti, Karim Ibnmajdoub, Taoufiq Harmouch, Khalid Mazaz, Khalid AitTaleb
Journal of Medical Case Reports , 2011, DOI: 10.1186/1752-1947-5-361
Abstract: A 21-year-old Caucasian Moroccan woman with vague abdominal discomfort and associated distention, during the previous 2 years, without other symptoms, presented to our hospital. Her past medical history was unremarkable. On physical examination, a mobile, painless and relatively hard abdominal mass was palpated. The laboratory examination and abdominal radiograph were unremarkable. Abdominal radiologic imaging showed a cystic mass of 35 × 20 × 10 cm that occupied the entire anterior and right abdominal cavity. Radical excision of the cyst was performed by midline laparotomy without any damage to the adjacent abdominal organs. The histopathological diagnosis was simple mesothelial cyst. The postoperative course was uneventful with no recurrence.A peritoneal simple mesothelial cyst is a quite rare abdominal tumor, that must always be considered in differential diagnosis of pelvic cystic lesions and other mesenteric cysts. The treatment of choice is the complete surgical excision of the cyst.According to Perrot classification, the peritoneal simple mesothelial cyst (PSMC), benign cystic mesothelioma and malignant cystic mesothelioma are mesenteric cysts (MC) of mesothelial origin [1]. The other MC types are non-pancreatic pseudocysts, dermoid cysts and cysts of lymphatic, enteric or urogenital origin [1]. PSMC is very rare, with only about 900 reported MC cases in the literature [2,3]. The cyst size ranges from a few centimeters to 40 cm [2,4,5]. The PSMC is usually asymptomatic, but occasionally presents with various, non-specific symptoms. The lack of specific symptoms and the rarity of PSMC, makes correct pre-operative diagnosis difficult.We present the case of a woman with a giant PSMC that was successfully managed by complete surgical excision, which is the treatment of choice of this lesion.A 21-year-old Caucasian Moroccan woman with vague abdominal discomfort and associated distention, during the previous two years, without other symptoms was admitted to our hos
Eccrine carcinoma : a rare cutaneous neoplasm
Karima Idrissi Serhrouchni, Taoufiq Harmouch, Laila Chbani, Hind El Fatemi, Mohammed Sekal, Nawal Hammas, Meriem Soughi, Loubna Benchat, Afaf Amarti
Diagnostic Pathology , 2013, DOI: 10.1186/1746-1596-8-15
Abstract: In our case, we present a 46- year-old female with a recurring exophytic tumor on the right lower extremity, without local extension.The initial tumor was biopsied, excised and diagnosed as an eccrine carcinoma.The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/3568051328673318 webcite.Malignant cutaneous adnexal neoplasms are a large and varied group, in particular eccrine carcinoma. They are one of the most challenging areas of Dermatopathology [1].Eccrine and apocrine neoplasms present a bewildering array of morphologies which often defy precise classification [2].The purpose of this case is to discuss the most common problems concerning the classification of this rare neoplasm and report the aim of the immunohistochemical profiles in differential diagnosis between a primitive eccrine carcinoma of the skin and a secondary neoplasm.In July 2012, a 45-year-old Moroccan woman presented to the department of Dermatology of Hassan II University Hospital of Fez with a 25-year-history of primary infertility, and an 18-month-history of an exophytic mass at the posterior right lower extremity, gradually increasing in size. She was otherwise healthy and had no systemic symptoms. Physical examination showed an ulcerative and bourgeoning mass of 15 cm with bleeding and purulent features (Figure 1). Biological tests included a complete blood count, routine blood and urine chemistry were normal, except for elevated LDH. Tumor markers as like as CA 19–9, CA 125, CA 15–3 were normal. MRI of the leg showed a subcutaneous infiltrative process coming into contact with the muscle fascia.The rest of the radiological examination, including radiography of the lung, abdominopelvic ultrasonography, computed tomographic thoraco-abdomino-pelvic scan, was normal.The mammography and ultrasound examination objectified a 4 mm measuring benign cystic lesion of the left breast classified ACR 3, requiring supervision during six months.After biops
Paragangliome malin orbitaire, à propos d’un cas
Idriss Benatiya Andaloussi, Mustapha Maaroufi, Mohammed Benzagmout, Taoufiq Harmouch, Meryem Abdellaoui, Salima Bhallil, Siham Tizniti, Mohammed Chaoui Elfaiz, Afaf Amarti, Hicham Tahri
Pan African Medical Journal , 2012,
Abstract: Les paragangliomes sont des tumeurs neuroendocrines développées aux dépens du système nerveux parasympathique. Ils peuvent se localiser n’ importe où dans l’organisme depuis la tète et cou jusqu’au pelvis. La localisation orbitaire de cette tumeur est très rare. Nous présentons le cas d’un patient agé de 37 ans qui présente depuis 4 mois une exophtalmie unilatérale droite, d’installation progressive, sans douleur ni baisse de l’acuité visuelle associés. L’examen général montre une tuméfaction sous le cuire chevelu, sans adénopathies locorégionales ni hépato ou splénomégalie. La tomodensitométrie retrouve un processus tumoral occupant le cadran supéro-externe de l’orbite droite, mesurant 38 mm de grand axe, envahissant la paroi supérieure et externe de l’orbite avec une importante ostéolyse. Un body scan révèle alors une métastase pulmonaire. L’examen histopathologique complétés par l’immunohistochimie, réalisé après biopsie, révèle un marquage cytoplasmique par l’anticorps anti-chromogranin, l’anticorps anti-synaptophysine et un marquage des vaisseaux par l’anticorps anti-CD31 soulignant l'architecture en zellbalen des nids tumoraux. Cet aspect est en faveur d’un paragangliome malin. Une exérèse chirurgicale incomplète suivie d’une radiothérapie adjuvante, sont alors réalisés. L’origine exacte de cette tumeur au sein de l’orbite reste très controversée. L’exophtalmie reste le principal signe révélateur. La tomodensitométrie, l’imagerie par résonnance magnétique et la scintigraphie au Metaiodobenzylguanidine radioinonisée à l’iode (MIBG-I131) permettent d’orienter le diagnostic et faire un bilan d’extension de la tumeur. Le diagnostic de certitude repose sur l’histopathologie et l’immunohistochimie. L'excision totale de la lésion est le traitement de choix pour les lésions bien délimitées. Dans les formes plus étendues le traitement repose sur l’excision incomplète associée à une radiothérapie adjuvante ou au MIBG I 131. La localisation orbitaire du paragangliome reste très rare. Son diagnostic est difficile et repose essentiellement sur l’immunohistochimie. Son pronostic dépend essentiellement de l’extension locale et de la présence de métastases à distance qui signe le caractère malin du paragangliome. Pan African Medical Journal 2012; 12:37
Study of Ionospheric Variability Using GNSS Observations  [PDF]
Jouan Taoufiq, Bouziani Mourad, Azzouzi Rachid, Christine Amory-Mazaudier
Positioning (POS) , 2018, DOI: 10.4236/pos.2018.94006
Abstract: With the increasing number of applications of Global navigation satellite system, the modeling of the ionosphere is a crucial element for precise positioning. Indeed, the ionosphere delays the electromagnetic waves which pass through it and induces a delay of propagation related to the electronic density (TEC) Total Electronic Content and to the frequency of the wave. The impact of this ionospheric error often results in a poor determination of the station’s position, particularly in strong solar activity. The first part of this paper focuses on a bibliographic study oriented first of all on the study of the ionosphere in relation to solar activity and secondly on the determination of the total electron content using GNSS measurements from the IGS network reference stations. Measurements were made on two permanent stations “RABT”, “TETN”. We selected years of GNSS measurements to evaluate the geomagnetic impact on the ionosphere, 2001, 2009 and 2013. A description of the ionospheric disturbances and geomagnetic storms was analyzed by determination of TEC, especially in high solar activity. The results show a strong dependence of the ionospheric activity with the geomagnetic activity.
Commutativity conditions on derivations and Lie ideals $σ$-prime rings
L. Oukhtite,S. Salhi,L. Taoufiq
Mathematics , 2009,
Abstract: Let $R$ be a 2-torsion free $\sigma$-prime ring, $U$ a nonzero square closed $\sigma$-Lie ideal of $R$ and let $d$ be a derivation of $R$. In this paper it is shown that: 1) If $d$ is centralizing on $U$, then $d = 0$ or $U \subseteq Z(R)$. 2) If either $d([x, y]) = 0$ for all $x, y \in U$, or $[d(x), d(y)] = 0$ for all $x, y \in U$ and $d$ commutes with $\sigma$ on $U$, then $d = 0$ or $U \subseteq Z(R)$.
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