oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 161 )

2018 ( 308 )

2017 ( 276 )

2016 ( 376 )

Custom range...

Search Results: 1 - 10 of 167539 matches for " Tangour E "
All listed articles are free for downloading (OA Articles)
Page 1 /167539
Display every page Item
The impact of vitamin D deficiency on immune T cells in asthmatic children: a case-control study
Maalmi H, Berra es A, Tangour E, Ammar J, Abid H, Hamzaoui K, Hamzaoui A
Journal of Asthma and Allergy , 2012, DOI: http://dx.doi.org/10.2147/JAA.S29566
Abstract: ct of vitamin D deficiency on immune T cells in asthmatic children: a case-control study Original Research (4185) Total Article Views Authors: Maalmi H, Berra es A, Tangour E, Ammar J, Abid H, Hamzaoui K, Hamzaoui A Published Date May 2012 Volume 2012:5 Pages 11 - 19 DOI: http://dx.doi.org/10.2147/JAA.S29566 Received: 29 December 2011 Accepted: 14 February 2012 Published: 09 May 2012 Ha fa Maalmi,1,2 Anissa Berra es,1,2,3 Eya Tangour,1,2,3 Jamel Ammar,1,2,3 Hanadi Abid,1,2,3 Kamel Hamzaoui,1,2 Agnes Hamzaoui1,2,3 1Department of Basic Sciences, Medicine School of Tunis, University Tunis El Manar, Tunis; 2Unit Research, Homeostasis and Cell Dysfunction, Ariana; 3Department of Pneumopediatry, A Mami Hospital, Ariana, Tunisia Background: Vitamin D exerts profound effects on both adaptive and innate immune functions involved in the development and course of autoimmune and inflammatory diseases. As the incidence of vitamin D insufficiency is surprisingly high in the general population, experimental studies have started to investigate whether vitamin D levels (measured as serum 25 hydroxy vitamin D-25[OH]D) are correlated with immune cells and clinical parameters. Purpose: The aim of the present research was to investigate serum vitamin D status in a case-control study in children with asthma and to study associations between vitamin D levels and certain immunological parameters. Materials and methods: A case control study of thirty-nine children with clinically controlled asthma was enrolled to assess the relationship between serum vitamin D concentrations and disease activity. Vitamin D was assayed with a radioimmunoassay kit. We evaluated the relationship between vitamin D concentrations and forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and the FEV1/FVC ratio. Correlations between inflammatory mediators, Th1, Th2, Th17, and regulatory T cells (Treg) and vitamin D were investigated. Results: Only 15.38% of our asthmatic children had a sufficient serum 25(OH)D (≥30 ng/mL) whereas 80% of healthy children expressed sufficient levels. Deficient values of vitamin D (<20 ng/mL) were observed in 17 (43.59%) asthmatic patients (14.40 ± 3.30 ng/mL; P = 0.0001). Deficiency was not observed in controls. Th1/Th2 ratio was significantly correlated to 25(OH)D level (r = 0.698; P = 0.0001). A significant negative correlation was observed between serum interleukin-17 and vitamin D levels in young asthmatics (r = -0.617; P = 0.001). A significant correlation was observed between CD25+Foxp3+ Treg cells and vitamin D values in asthmatics (r = 0.368; P = 0.021). Conclusion: Even in a southern Mediterranean country, hypovitaminosis D is frequent in children with asthma. Our findings suggest that vitamin D is an important promoter of T cell regulation in vivo in young asthmatics.
The impact of vitamin D deficiency on immune T cells in asthmatic children: a case-control study
Maalmi H,Berraïes A,Tangour E,Ammar J
Journal of Asthma and Allergy , 2012,
Abstract: Ha fa Maalmi,1,2 Anissa Berra es,1,2,3 Eya Tangour,1,2,3 Jamel Ammar,1,2,3 Hanadi Abid,1,2,3 Kamel Hamzaoui,1,2 Agnes Hamzaoui1,2,31Department of Basic Sciences, Medicine School of Tunis, University Tunis El Manar, Tunis; 2Unit Research, Homeostasis and Cell Dysfunction, Ariana; 3Department of Pneumopediatry, A Mami Hospital, Ariana, Tunisia Background: Vitamin D exerts profound effects on both adaptive and innate immune functions involved in the development and course of autoimmune and inflammatory diseases. As the incidence of vitamin D insufficiency is surprisingly high in the general population, experimental studies have started to investigate whether vitamin D levels (measured as serum 25 hydroxy vitamin D-25[OH]D) are correlated with immune cells and clinical parameters.Purpose: The aim of the present research was to investigate serum vitamin D status in a case-control study in children with asthma and to study associations between vitamin D levels and certain immunological parameters.Materials and methods: A case control study of thirty-nine children with clinically controlled asthma was enrolled to assess the relationship between serum vitamin D concentrations and disease activity. Vitamin D was assayed with a radioimmunoassay kit. We evaluated the relationship between vitamin D concentrations and forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and the FEV1/FVC ratio. Correlations between inflammatory mediators, Th1, Th2, Th17, and regulatory T cells (Treg) and vitamin D were investigated.Results: Only 15.38% of our asthmatic children had a sufficient serum 25(OH)D (≥30 ng/mL) whereas 80% of healthy children expressed sufficient levels. Deficient values of vitamin D (<20 ng/mL) were observed in 17 (43.59%) asthmatic patients (14.40 ± 3.30 ng/mL; P = 0.0001). Deficiency was not observed in controls. Th1/Th2 ratio was significantly correlated to 25(OH)D level (r = 0.698; P = 0.0001). A significant negative correlation was observed between serum interleukin-17 and vitamin D levels in young asthmatics (r = -0.617; P = 0.001). A significant correlation was observed between CD25+Foxp3+ Treg cells and vitamin D values in asthmatics (r = 0.368; P = 0.021).Conclusion: Even in a southern Mediterranean country, hypovitaminosis D is frequent in children with asthma. Our findings suggest that vitamin D is an important promoter of T cell regulation in vivo in young asthmatics.Keywords: vitamin D, Th17, Treg cells, asthma, children
Cluster Model of Formation of Subnuclear and Subatomic Objects  [PDF]
E. E. Lin
Journal of Modern Physics (JMP) , 2014, DOI: 10.4236/jmp.2014.53018
Abstract:

The paper describes the development results on one-dimensional (1D) asymptotic model of the formation kinetics for the objects (clusters) of subnuclear (quark) and subatomic (nuclear) matters. A concept of the objects distribution density wave φ(a, t) in space of sizes a lies in the basis for analytical description of the processes under consideration. The proposed formalism makes it possible to describe in an adequate way the final outcomes of the well-known catastrophic phenomena in the world of elementary particles. Mass characteristics of different processes of approach to equilibrium in nuclear reactions are calculated.

The Gene as Natural Nanomaterial for Treatment of Diseases  [PDF]
E. E. Escultura
Open Journal of Biophysics (OJBIPHY) , 2017, DOI: 10.4236/ojbiphy.2017.71003
Abstract: As an application of the grand unified theory (GUT) to medicine, this paper introduces two natural nanomaterials—the gene and electromagnetic wave. They are involved in the proposed treatment of genetic and infectious diseases. It introduces the superstring as the fundamental building block of matter and the basic constituent of dark matter, one of the two fundamental states of matter. It also introduces the primum, unit of visible or ordinary matter, the other fundamental state of matter. They are convertible to each other by the action of basic cosmic or electromagnetic waves. Eleven biological laws define biology as a biological and physical theory. The gene is the primitive ingredient of living things and, therefore, the beginning of biological life and the virus the simplest living thing. Treatment ranges from genetic modification and alteration to remove undesirable symptom through genetic sterilization to stop the spread of the disease and outright destruction of the disease. Genetic sterilization and outright destruction apply also to infectious diseases. The paper concludes with a blueprint for research and development of appropriate technologies for the treatment.
Extensions of the Constructivist Real Number System  [PDF]
E. E. Escultura
Advances in Pure Mathematics (APM) , 2018, DOI: 10.4236/apm.2018.88044
Abstract: The paper reviews the most consequential defects and rectification of traditional mathematics and its foundations. While this work is only the tip of the iceberg, so to speak, it gives us a totally different picture of mathematics from what we have known for a long time. This journey started with two teasers posted in SciMath in 1997: 1) The equation 1 = 0.99… does not make sense. 2) The concept \"\"?does not exist. The first statement sparked a debate that raged over a decade. Both statements generated a series of publications that continues to grow to this day. Among the new findings are: 3) There does not exist nondenumerable set. 4) There does not exist non-measurable set. 5) Cantor’s diagonal method is flawed. 6) The real numbers are discrete and countable. 7) Formal logic does not apply to mathematics. The unfinished debate between logicism, intuitionism-constructivism and formalism is resolved. The resolution is the constructivist foundations of mathematics with a summary of all the rectification undertaken in 2015, 2016 and in this paper. The extensions of the constructivist real number system include the complex vector plane and transcendental functions. Two important results in the 2015 are noted: The solution and resolution of Hilbert’s 23 problems that includes the resolution of Fermat’s last theorem and proof Goldbach’s conjecture.
ЕЛЕКТРОХ М ЧНИЙ СИНТЕЗ Д ОКСИДУ МАНГАНУ В ПРИСУТНОСТ ОН В Fe2+ ТА Co2+ Electrochemical synthesis of manganese dioxide in the presence of ions Fe2+ and Co2+ Электрохимический синтез диоксида марганца в присутствии ионов Fe2+ и Co2+
Г.В. Сокольський,Н.Д. ?ванова,С.В. ?ванов,E.?. Болдир?в
Proceedings of National Aviation University , 2009,
Abstract: Зразки д оксиду мангану отримано методом анодного осадження з фторвм сних електрол т в на основ сульфату мангану у присутност дом шок он в двовалентних зал за або кобальту. Отриман продукти характеризувалися методами ААС та ДТА. Проанал зовано вплив дом шок он в зал за кобальту на х м чний склад отриманих зразк в Manganese dioxide samples have been prepared by the anode deposition from fluoride containing electrolytes based on manganese sulphate at the presence of additives of iron(II), cobalt(II) ions. Obtained materials were characterised with AAS and DTA. The influence of doping by ions of iron(II) and cobalt(II) on the chemical composition of the samples obtained has been analysed. Образцы диоксида марганца получены методом анодного осаждения из фторсодержащих электролитов на основе сульфата марганца в присутствии примесей ионов двухвалентных железа или кобальта. Полученные продукты характеризовались методами ААС и ДТА. Проанализировано влияние примесей ионов железа и кобальта на химический состав полученных образцов.
Numerical Investigations of a New N-body Simulation Method  [PDF]
E. Vilkoviskij
International Journal of Astronomy and Astrophysics (IJAA) , 2012, DOI: 10.4236/ijaa.2012.23016
Abstract: Numerical investigation of a new similarity method (the Aldar-Kose method) for N-body simulations is described. Using this method we have carried out numerical simulations for two tasks: 1) calculation of the temporal behavior of different physical parameters of active galactic nuclei (AGN) containing a super massive black hole (SMBH), an accretion disk, and a compact stellar cluster; 2) calculation of the stellar capture rate to the central SMBH without accretion disk. The calculations show good perspectives for applications of the similarity method to optimize the evolution model calculations of large stellar systems and of AGN.
Studies on TiO2/Reduced Graphene Oxide Composites as Cathode Materials for Magnesium-Ion Battery  [PDF]
E. Sheha
Graphene (Graphene) , 2014, DOI: 10.4236/graphene.2014.33006
Abstract:

The aim of this work is to introduce a high performance cathode for magnesium-ion batteries. TiO2/reduced graphene oxide (rGO) composites were mixed in ball mill. The samples are charac- terized using XRD and SEM. The spex-milled composites exhibit better electrochemical perfor- mance with higher reversible capacity and excellent cyclability. The excellent electrochemical performance of TiO2/rGO composites is due to their unique structures, which intimately combine the conductive graphene nanosheets network with TiO2 nanoparticles and possess the characteristic parallel channels running along the [010] orientation, which allow easy Mg2+ transport. It was found that layered TiO2 and rGO nanosheets in the composite interlace with each other to form novel sandwich-structured microspheres, which exhibit preferable electrochemical performance in rechargeable Mg batteries.

Variable Thermal Comfort Index for Indoor Work Space in Office Buildings: A Study in Germany  [PDF]
E. Kuchen
Open Journal of Civil Engineering (OJCE) , 2016, DOI: 10.4236/ojce.2016.64054
Abstract: International standards state the thermal comfort requirements that office spaces must comply with. These are based on a model developed by Prof. Paul Ole Fanger of the Centre for Indoor Environment and Energy, Denmark. Today, forty-year research shows an evolution in these experiences. The work presented here is to develop a tool to evaluate the thermal comfort of working environments of office buildings. A methodology is devised on the basis of on-site measurements and questionnaire responses. For measurements, a mobile unit equipped with sensors is used, whereas the questionnaire obtains user responses on thermal quality of the work space. The thermal conditions of thirty office buildings presenting different acclimatization systems have been surveyed. The correlation between objective and subjective data allows developing a formula that shows the thermal comfort level for a given environment as a function of local aspects. For the surveyed buildings, the resulting comfortable temperature was 23.3, and the minimum percentage of user individuals experiencing discomfort with such temperature was 7%.
Linking Regional Science and Urban Economics: Long-Run Interactions among Preferences for Amenities and Public Goods  [PDF]
Philip E. Philip E. Graves
Modern Economy (ME) , 2012, DOI: 10.4236/me.2012.33035
Abstract: The linked nature of long-term patterns of urban deconcentration and regional change (from rustbelt to sunbelt in the U.S., but with similar phenomena increasingly world-wide) is analyzed in a framework that emphasizes heterogeneous human preferences. The focus is on the important interactions that exist between local and regional amenities, whether exogenous or endogenous. The central thesis is that persistent exogenous amenity variation among regions provides an underlying pattern of regional growth and decline. However, inappropriate provision of local public goods in central cities is seen to lead both to non-optimally large levels of suburbanization and to rates of regional change that are also non-optimally large.
Page 1 /167539
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.