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Search Results: 1 - 10 of 2674 matches for " Takeshi Yoshimura "
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Anti-hyperalgesic effects of calcitonin on neuropathic pain interacting with its peripheral receptors
Akitoshi Ito, Mineko Takeda, Takeshi Yoshimura, Takayuki Komatsu, Takeshi Ohno, Hiroshi Kuriyama, Akio Matsuda, Megumu Yoshimura
Molecular Pain , 2012, DOI: 10.1186/1744-8069-8-42
Abstract: Subcutaneous injection of elcatonin, a synthetic derivative of eel calcitonin, relieved hyperalgesia induced by chronic constriction injury (CCI). Real-time reverse transcriptase-polymerase chain reaction analysis revealed that the CCI provoked the upregulation of tetrodotoxin (TTX)-sensitive Nav.1.3 mRNA and downregulation of TTX-resistant Nav1.8 and Nav1.9 mRNA on the ipsilateral dorsal root ganglion (DRG), which would consequently increase the excitability of peripheral nerves. These changes were reversed by elcatonin. In addition, the gene expression of the calcitonin receptor and binding site of 125I-calcitonin was increased at the constricted peripheral nerve tissue but not at the DRG. The anti-hyperalgesic effect and normalization of sodium channel mRNA by elcatonin was parallel to the change of the calcitonin receptor expression. Elcatonin, however, did not affect the sensitivity of nociception or gene expression of sodium channel, while it suppressed calcitonin receptor mRNA under normal conditions.These results suggest that the anti-hyperalgesic action of calcitonin on CCI rats could be attributable to the normalization of the sodium channel expression, which might be exerted by an unknown signal produced at the peripheral nerve tissue but not by DRG neurons through the activation of the calcitonin receptor. Calcitonin signals were silent in the normal condition and nerve injury may be one of triggers for conversion of a silent to an active signal.
Irradiance and Developmental Stages of Crown Architecture Affect Shoot Production in Rhododendron reticulatum  [PDF]
Kenichi Yoshimura
American Journal of Plant Sciences (AJPS) , 2013, DOI: 10.4236/ajps.2013.45A011
Abstract:

Plasticity in crown architecture, contributing to leaf arrangement within crown, is an important feature for whole plant carbon assimilation and survival. In this study, I examined the plasticity in crown architecture to light condition and developmental stage by the changes in shoot production. Rhododendron reticulatum expands crown with orthotropic growth in monopodial branching in young stage, but orthotropic growth is ceased in adult stage. Main stem of young crown is described with monopodial branching regardless of light environment. But multi-layer crown is observed in sun-lit environment rather than mono-layer crown in adult stage. Long shoot production for each branching system (foliage derived from sympodial branching) in young crown is associated with local light environment, but not in adult crown. Long shoot production rate is correlated with long shoot production rate of its mother shoot in young crown, but not in mono-layer crown. These results suggest that young crown expands branches to sun-lit position whereas adult crown reduces congestion of shoots with stochastic shoot production regardless of shoot production of mother shoots. I concluded that both light and developmental stage are important factors for shoot production and constructing crown architecture.

Erratum to “Irradiance and Developmental Stages of Crown Architecture Affect Shoot Production in Rhododendron reticulatum” [American Journal of Plant Sciences 4 (2013) 69-76]  [PDF]
Kenichi Yoshimura
American Journal of Plant Sciences (AJPS) , 2014, DOI: 10.4236/ajps.2014.513214
Abstract:

The original online version of this article (Yoshimura, K. (2013) Irradiance and Developmental Stages of Crown Architecture Affect Shoot Production in Rhododendron reticulatum. American Journal of Plant Sciences, 4, 69-76. http://dx.doi.org/10.4236/ajps.2013.45A011) was published as a single-author paper mistakenly. To reflect the contribution and responsibility of the second author as well as the affiliations of the authors at the time of the study, we have revised the authorship and author affiliations of this article. The author wishes to correct the errors as:


Kenichi Yoshimura1,2, Hiroaki Ishii1

1Graduate School of Science and Technology, Kobe University, Kobe, Japan

2Present Address: Center for Ecological Research, Kyoto University, Otsu, Japan

Email:

Obstructive azoospermia as an unusual complication associated with herniorrhaphy of an omphalocele: a case report
Kazunari Tsuchihashi, Kazutoshi Okubo, Kentaro Ichioka, Takeshi Soda, Koji Yoshimura, Akihiro Kanematsu, Osamu Ogawa, Hiroyuki Nishiyama
Journal of Medical Case Reports , 2011, DOI: 10.1186/1752-1947-5-234
Abstract: A 30-year-old Japanese man was diagnosed with obstructive azoospermia. He had undergone herniorrhaphy of an omphalocele immediately after birth. Reconstruction surgery of both seminal tracts was performed to pursue the possibility of naturally achieved pregnancy. Intra-operative findings demonstrated that both vasa deferentia were interrupted at the internal inguinal rings, although the abdominal end of the right vas leading to the seminal vesicle was found in the abdominal cavity. The discharge from the stump of the testicular end had no sperm, although the right epididymal tubules were dilated with motile sperm. Therefore, we performed right-sided vasovasostomy in the internal inguinal ring and ipsilateral epididymovasostomy simultaneously.To the best of our knowledge, this is the first report describing obstructive azoospermia as an unusual complication of herniorrhaphy of an omphalocele. It is important to pay attention to the existence of seminal tracts in such surgery as well as in inguinal herniorrhaphy.Obstructive azoospermia is one cause of male infertility. Obstruction of the seminal tracts can be caused by iatrogenic damage, by a congenital anomaly or by infectious diseases [1]. Although the most common iatrogenic cause is bilateral repair of an inguinal hernia, here we present a case of obstructive azoospermia caused by herniorrhaphy of an omphalocele immediately after birth. As far as we are aware, this is the first such report.A 30-year-old Japanese man who had undergone herniorrhaphy for an omphalocele immediately after birth was referred to our hospital. He presented to our hospital with 1 year of infertility after his marriage. Multiple semen analyses revealed azoospermia, but a scrotal examination revealed no abnormalities in the testes or in the vas deferens or epididymis on both sides. Magnetic resonance imaging of the scrotum revealed no abnormal findings in the seminal vesicles, the prostate or the ejaculatory ducts. An endocrinological examina
Effects of candesartan in hypertensive patients with type 2 diabetes mellitus on inflammatory parameters and their relationship to pulse pressure
Masaya Sakamoto, Hirofumi Suzuki, Takeshi Hayashi, Hiroyuki Iuchi, Tsuyoshi Isaka, Noriko Sakamoto, Yosuke Kayama, Katsuyoshi Tojo, Michihiro Yoshimura, Kazunori Utsunomiya
Cardiovascular Diabetology , 2012, DOI: 10.1186/1475-2840-11-118
Abstract: We administered candesartan therapy (12?mg daily) for 6?months and evaluated whether there was improvement in serum inflammatory parameters high molecular weight adiponectin (HMW-ADN), plasminogen activator inhibitor-1 (PAI-1), highly sensitive C-reactive protein (Hs-CRP), vascular cell adhesion molecule-1 (VCAM-1) in serum and urinary-8-hydroxydeoxyguanosine (U-8-OHdG). We then analyzed the relationship between the degree of lowering of blood pressure and inflammatory factors and the relationship between pulse pressure and inflammatory factors. Finally, we analyzed predictive factors in patients who received the protective benefit of candesartan.After 6?months of treatment, significant improvements from baseline values were observed in all patients in HMW-ADN and PAI-1 but not in Hs-CRP, VCAM-1 and U-8-OHdG. Multilinear regression analysis was performed to determine which factors could best predict changes in HMW-ADN and PAI-1. Changes in blood pressure were not significant predictors of changes in metabolic factors in all patients. We found that the group with baseline pulse pressure <60?mmHg had improved HMW-ADN and PAI-1 values compared with the group with baseline pulse pressure ≥ 60?mmHg. These results suggest that pulse pressure at baseline could be predictive of changes in HMW-ADN and PAI-1.Candesartan improved inflammatory parameters (HMW-ADN and PAI-1) in hypertensive patients with type 2 diabetes mellitus of long duration independent of blood pressure changes. Patients with pulse pressure <60?mmHg might receive protective benefits by candesartan.UMIN000007921Almost half of type 2 diabetic patients are reported to have hypertension during their lifetime [1], and the coexistence of hypertension and diabetes mellitus especially increases the risk of cardiovascular events. Moreover, much of this excess risk is attributable to coexistent hypertension [2]. Treatment of hypertension in patients with type 2 diabetes mellitus of short duration has been shown to re
Matching Accuracy Analysis of Fingerprint Templates Generated by Data Processing Method Using the Fractional Fourier Transform  [PDF]
Reiko Iwai, Hiroyuki Yoshimura
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2011, DOI: 10.4236/ijcns.2011.41003
Abstract: The matching accuracy of the fingerprint templates which were generated by our previously proposed data processing method using the fractional Fourier transform (FRT) was analyzed. The minimum error rate (MER) derived from the false acceptance rate (FAR) and the false rejection rate (FRR) is the criterion of the matching accuracy in this study, and was obtained statistically by the peak value of the normalized cross-correlation function between the fingerprint template and the intensity FRT of the subject’s fingerprint. In our analysis, the fingerprint template was obtained as the intensity FRT of one-dimensional (1D) finite rectangular wave by which a line of a real fingerprint image is modeled. Moreover, various modified 1D finite rectangular waves were generated to derive the FAR. Furthermore, the 1D finite rectangular wave with random noise regarded as dirt of a fingerprint and the one with random vanishing ridges regarded as damage of a fingerprint were generated to derive the FRR. As a result, it was clarified that fingerprint templates generated by our data processing method using the FRT could provide high matching accuracy in the fingerprint authentication from the viewpoint of the MER.
Improved Authentication Accuracy by Individually Set Orders of the Fractional Fourier Transform and Effects of Damage of Fingerprint Image on Authentication Accuracy  [PDF]
Reiko Iwai, Hiroyuki Yoshimura
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2011, DOI: 10.4236/ijcns.2011.432095
Abstract: Recently, ubiquitous personal devices with a fingerprint authentication function have been increasing. In such devices, there is almost no possibility of the authentication by impostors unless they are lost or stolen. However, for example, in the management of entering and leaving a building, not only the fingerprint authentication device but also the other authentication measures, such as an IC card, a key, etc., are generally used. In our previous studies, we have analyzed the authentication accuracy of the fingerprint authentication devices for personal possessions where other authentication measures are not needed. As a result, we made clear that the authentication accuracy in our method has extremely high compared with that in the marketed compact fingerprint authentication products, even if dirt, sebum, etc., are attached to the fingertip and there are scratches. In this study, we analyze the damage ratio of the fingerprint image where the genuine authentication can be conducted without problems, because the fingertip is easily got large cuts. Moreover, we analyze the impostor authentication of the fingerprint authentication devices for public possessions in the two cases of without and with other authentication measures. As a result, it is found that clearer impostor authentication can be achieved in the case of with other authentication measures. In addition, it is found that the damage ratio of the fingerprint image to conduct clearer genuine authentication without the image correction is less than 14.3%.
Accuracy Analysis in Fingerprint Authentication Using the Fractional Fourier Transform without Misalignment Correction of Scanned Images  [PDF]
Reiko Iwai, Hiroyuki Yoshimura
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2012, DOI: 10.4236/ijcns.2012.53022
Abstract: In many fingerprint authentication devices, a frame to insert the fingertip or a hollow to put the fingertip is used to avoid the position or rotation misalignment of a newly scanned genuine fingerprint image, when the fingerprint authentication is conducted. Moreover, the misalignment correction by the numerical calculation is indispensable for the fingerprint authentication devices to achieve the high accuracy. In this study, we investigated the effects of misalignment of the scanned genuine fingerprint image with the one used for generating the template on the accuracy in our fingerprint authentication method using the fractional Fourier transform (FRT). As a result, it was found that our method can achieve high authentication accuracy under the condition that the position-misalignment ratio is 17.6% or less and the rotation misalignment (rotation angle) is 28 degrees or less, even if the misalignment correction is not conducted.
A New Method for Improving Robustness of Registered Fingerprint Data Using the Fractional Fourier Transform  [PDF]
Reiko Iwai, Hiroyuki Yoshimura
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2010, DOI: 10.4236/ijcns.2010.39096
Abstract: In the light of a limited number of related studies, a new data processing method in fingerprint authentication using the fractional Fourier transform (FRT) was proposed for registered fingerprint data. In this proposal, protection of personal information was also taken into account. We applied the FRT instead of the conventional Fourier transform (FT) which has been being used as one of the representative fingerprint authentication algorithm. Our method led to solve the problem of current registration method and the robustness was verified. In this study, a modeled fingerprint image instead of the original raw fingerprint images was analyzed in detail to make the characteristic clear. As one dimensional (1D) modeled fingerprint image, we used the finite rectangular wave which is regarded as the simplification of the grayscale distribution in an arbitrary scanned line of the raw fingerprint images. As a result, it was clarified that the data processed by the FRT provides higher safety than the case processed by the FT, because it is difficult to specify the orders from the intensity distribution of FRTs (the intensity FRTs) when the combination of the various FRT’s order at every scanned line is used.
Effect of Ultrasonic Irradiation Conditions on Metal Surface during Multifunction Cavitation  [PDF]
Masataka Ijiri, Toshihiko Yoshimura
Materials Sciences and Applications (MSA) , 2018, DOI: 10.4236/msa.2018.98050
Abstract: Processing using multifunction cavitation (MFC) has recently enabled functional characteristics to be imparted to various materials. It is possible to process a material surface in the same manner as with conventional water jet (WJ) peening; however, the cavitation bubble temperature is different. To further improve this MFC technology, we examine the surface re-forming of low alloy steel (JIS-SCM435) using MFC with various modes of ultrasonic waves. The ultrasonic equipment used for MFC processing includes dual, single, pulse and frequency modulation (FM) ultrasonic modes. Improvement of the residual stress and corrosion resistance was confirmed for all modes. The dual mode showed the maximum values of residual compressive stress and surface potential. The sound pressure at the machining spot was the highest with dual mode, and the temperature in the bubble generated by the WJ nozzle was highest and the amount of dissolved oxygen was lowest. Improvement of the residual stress and corrosion resistance was promoted because the temperature and pressure in the bubble interior during processing was higher than in the other modes.
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