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Search Results: 1 - 10 of 117796 matches for " T;Feksa "
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Enterovirus infections and type 1 diabetes mellitus: is there any relationship?
Tavares, RG;Trevisol, RB;Comerlato, J;Dalzochio, T;Feksa, LR;Spilki, FR;Berlese, DB;
Journal of Venomous Animals and Toxins including Tropical Diseases , 2012, DOI: 10.1590/S1678-91992012000100002
Abstract: several health organizations have classified diabetes mellitus, a metabolic syndrome, as the epidemic of the century, since it affects millions of people worldwide and is one of the top ten causes of death. type 1 diabetes is considered to be an autoimmune disease, in which autoaggressive t cells infiltrate the islets of langerhans in the pancreas, leading to the destruction of insulin producing beta cells. the risk of the disease is modulated by genetic factors, mainly genes coding for human leukocyte antigens (hla). however, the incidence of this disease has increased significantly during the recent decades, which cannot be explained only by genetic factors. environmental perturbations have also been associated to the development of diabetes. among these factors, viral triggers have been implicated; particularly enteroviruses, which have been associated to the induction of the disease. supporting the hypothesis, numerous lines of evidence coming from mouse models and patients with this type of diabetes have shown the association. the present review aims to provide some understanding of how type 1 diabetes occurs and the possible role of enterovirus in this pathology.
Frequency of the anti-glutamic acid decarboxylase immunological marker in patients with diabetes duration longer than three years in southern Brazil
Moreira, Marina Carolina;Lara, Gustavo Müller;Linden, Rafael;Feksa, Luciane Rosa;Tavares, Rejane Giacomelli;Almeida, Sabrina Esteves de Matos;Berlese, Daiane Bolzan;
Sao Paulo Medical Journal , 2011, DOI: 10.1590/S1516-31802011000300002
Abstract: context and objective: the anti-gad (glutamic acid decarboxylase) antibody is considered to be an important marker for type 1 diabetes mellitus (dm1), with frequency that varies depending on the population studied and the duration of the disease. therefore, the aim of this study was to determine the frequency of this autoantibody in a group of patients in southern brazil with dm1 that had been diagnosed more than three years previously. design and setting: analytical cross-sectional study with a control group conducted at the biomedicine laboratory of universidade feevale. methods: this study was conducted between june 2007 and december 2008, and 109 individuals were enrolled during this period. fifty-eight were dm1 patients and 51 were individuals free from dm1 and without any history of diabetes, who constituted the control group. results: in the dm1 group, the mean age was 27 ± 1.7 years and 50% were men. the mean fasting blood glucose in the dm1 group was 208 ± 15 mg/dl and mean hba1c (glycosylated hemoglobin) was 8.7 ± 0.25%. in the control group, the mean fasting blood glucose and hba1c were 82 mg/dl and 5.0% respectively. thirty-seven individuals with dm1 (63.8%) were positive for anti-gad, and this proportion was significantly larger than in the control group. conclusions: these results show the high prevalence of anti-gad in the population of diabetic patients in southern brazil, thus indicating that the antibody was still present a long time after the disease had been diagnosed.
REGULARYFRAMWORK AND LEGAL BASE OF ELECTRONIC DOCUMENT CIRCULATION НОРМАТИВНО-ПРАВОВА БАЗА ЕЛЕКТРОННОГО ДОКУМЕНТООБ ГУ
T.Г. Омельченко,Н.А. Джанджгава
Information Technologies and Learning Tools , 2010,
Abstract: The general characteristic of legal base of electronic document circulation is presented in the article. It legislatively regulates the relations which connected with the information and information communication technologies. There is presented the list of the basic acts of regulation of sphere of information relations. У робот подано загальну характеристику нормативно-правово бази, яка законодавчо регулю в дносини, пов'язан з нформац ю, нформац йно-комун кац йними технолог ями, представлено перел к основних законодавчих акт в регулювання сфери нформац йних в дносин.
THE APPROACH OF COMPETENCE AT THE STUDY OF MATHEMATICAL INFORMATICS IN A PEDAGOGICAL UNIVERSITY КОМПЕТЕНТН СНИЙ П ДХ Д ПРИ ВИВЧЕНН МАТЕМАТИЧНО НФОРМАТИКИ” У ПЕДАГОГ ЧНОМУ УН ВЕРСИТЕТ
T.П. Кобильник
Information Technologies and Learning Tools , 2010,
Abstract: In the paper the approach of competence at the study of mathematical informatics in a pedagogical university is considered. The special attention is paid to forming of professional pedagogical and educational-cognitive competences. The example of tasks on which formed a competence at the study of mathematical informatics is resulted. У статт розглянуто компетентн сний п дх д при вивченн математично нформатики у педагог чному ун верситет . Особливу увагу звернено на формування профес йно педагог чно та навчально-п знавальну компетентност . Наведено приклад завдань, як сприяють формуванню компетентностей при вивченн математично нформатики.
SYSTEM OF THE AUTOMATIC DOCUMENT PROCESSING IN SHELL OF BASE SOFTWARE СИСТЕМА АВТОМАТИЗОВАНОГО ДОКУМЕНТООБ ГУ В ОБОЛОНЦ БАЗОВОГО ПРОГРАМНОГО ЗАБЕЗПЕЧЕННЯ
В.Ю. Биков,T.О. Дерба
Information Technologies and Learning Tools , 2010,
Abstract: In the article the automatic system of the document processing, created with use of Microsoft Access – a component part of Microsoft Office is offered. This system can be used at school and Institutions of education with one computer or with system of 15 ones connecting in the local net. У статт запропоновано для ознайомлення автоматизовану систему документооб гу, створену з використанням Microsoft Access – складово частини Microsoft Office. Ця система може використовуватися в школах установах осв тньо галуз на одному комп’ютер чи на систем до 15 комп’ютер в, пов’язаних локальною мережею.
MODERN APPROACHES AND PRINCIPLES OF PORTAL BUILDING ТЕХНОЛОГ ЧН ОСНОВИ СТВОРЕННЯ ТА П ДТРИМКИ ПОРТАЛ В
Н.Т. Задорожна,T.Г. Омельченко
Information Technologies and Learning Tools , 2010,
Abstract: The paper presents the analysis of modern state of development and use of Internet portals, the peculiarities of approaches to creation and introduction of portals in educational system are described. В робот анал зуються принципи розробки та використання нтернет-портал в, описуються особливост п дход в до створення та впровадження портал в у систему осв ти.
REVIEW OF MODERN TOOLS OF INFORMATION AND COMMUNICATION TECHNOLOGIES IN THE MANAGEMENT OF SECONDARY EDUCATION ОГЛЯД СУЧАСНИХ ЗАСОБ В НФОРМАЦ ЙНО-КОМУН КАЦ ЙНИХ ТЕХНОЛОГ Й В УПРАВЛ НН СЕРЕДНЬОЮ ОСВ ТОЮ
T.О. Дерба
Information Technologies and Learning Tools , 2010,
Abstract: There are presented the up-to-date situation with information and communication technology use in the management of secondary education; information and communication technologies (ICT), that practically used in educational establishments are considered. There are some examples of educational institutions using IСT for the automation of management. У статт показаний зр з сучасного стану використання нформац йно-комун кац йних технолог й в управл нн середньою осв тою, розглянут нформац йно-комун кац йн технолог ( КТ), як на практиц використовуються в загальноосв тн х закладах, наведен в дгуки навчальних заклад в, як використовують КТ для автоматизац управл ння
EVALUATION OF INTEGRALS OF FUNCTIONS OF COMPLEX VARIABLE BY USING THE RESIDUES IN COMPUTER MATHEMATICS SYSTEMS ОБЧИСЛЕННЯ НТЕГРАЛ В В Д ФУНКЦ Й КОМПЛЕКСНО ЗМ ННО ЗА ДОПОМОГОЮ ЗАЛИШК В В СИСТЕМАХ КОМП’ЮТЕРНО МАТЕМАТИКИ
Н.Д. Парфьонова,T.В. Клочко
Information Technologies and Learning Tools , 2010,
Abstract: The article describes the methodology of teaching one of the major topics of the course of complex analysis using the system Maple. It also demonstrates how the use of computer mathematics systems facilitates the evaluation of students by the teacher during organization of independent work. В статт наведено методику викладання мабуть одн з найважлив ших тем курсу комплексного анал зу з використанням системи Maple; демонстру ться, як використання систем комп’ютерно математики полегшу викладачев оц нювання роботи студент в та при орган зац х самост йно роботи.
USE OF VEB 2.0 SOCIAL SERVICES FOR PLANNING OF INFORMATIVE SYSTEMS ВИКОРИСТАННЯ СОЦ АЛЬНИХ СЕРВ С В ВЕБ 2.0 ДЛЯ ПРОЕКТУВАННЯ НФОРМАЦ ЙНИХ СИСТЕМ
T.Г. Омельченко
Information Technologies and Learning Tools , 2010,
Abstract: In the article the definitions and the characteristic of Web 2.0 social networks and services are presented as well as tendencies of their development, approaches of use of Web 2.0 social services and technologies in information systems are considered and analyzed. Requirements to technological maintenance of information system “Planning of scientific researches in NPA of Ukraine” are analyzed. В робот представлен визначення характеристика соц альних мереж послуг Веб 2.0 та тенденц хнього розвитку, розглянуто проанал зовано напрямки використання соц альних послуг та технолог й Веб 2.0 в нформац йних системах. Проанал зовано вимоги до технолог чного забезпечення нформац йно системи “Планування наукових досл джень в АПН Укра ни”.
In memoriam: Люба Огненова-Маринова (1922–2012)
Tотко Стоянов
Bulgarian e-Journal of Archaeology , 2012,
Abstract: In memoriam: Luba Ognenova-Marinova (1922–2012)Totko Stoyanov
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