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Search Results: 1 - 10 of 234342 matches for " T. K. Mukendi "
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Sickle Cell Trait, Hemoglobin Levels and Anemia among Black Patients with Predialysis Chronic Kidney Disease: A Post Hoc Analysis  [PDF]
F. B. Lepira, T. K. Mukendi, F. I. N. Mbutiwi, J. R. Makulo, E. K. Sumaili, P. K. Kayembe, N. M. Nseka
World Journal of Cardiovascular Diseases (WJCD) , 2016, DOI: 10.4236/wjcd.2016.68029
Abstract: Objective: To assess the relationship between SCT, hemoglobin levels and anemia in CKD black patients. Method: A post-hoc analysis of data from 188 patients, enrolled in a cross-sectional study of sickle cell trait (SCT) and chronic kidney disease (CKD), was performed to assess the relationship between SCT, hemoglobin (Hb) levels and anemia defined as Hb < 12 g/dl in men and <11 g/dl in women. Student t test, Mann Whitney and Chi square test were used as appropriate for different comparisons. P < 0.05 defined the level of statistical significance. Results: SCT (HbAS) and normal hemoglobin (HbAA) were present in 39 (21%) and 149 (79%) CKD patients, respectively. Despite similar estimated GFR (eGFR) and age, HbAS patients had significantly lower Hb levels (8.8 ± 1.8 vs 10 ± 2.2 g/dl; p = 0.001) and a higher proportion of anemia (95% vs 72%, p = 0.001). In multiple linear regression analysis, eGFR, BMI, SBP and SCT emerged as independent determinants of Hb levels. The presence of SCT was associated with 1.185 g/dl decrease in Hb levels. Conclusion: In the present case series, SCT was associated with lower Hb levels suggesting its potential contribution to the pathogenesis of CKD-associated anemia.
Epidemiology, clinical, immune, and molecular profiles of microsporidiosis and cryptosporidiosis among HIV/AIDS patients
Wumba R, Longo-Mbenza B, Menotti J, Mandina M, Kintoki F, Situakibanza NH, Kakicha MK, Zanga J, Mbanzulu-Makola K, Nseka T, Mukendi JP, Kendjo E, Sala J, Thellier M
International Journal of General Medicine , 2012, DOI: http://dx.doi.org/10.2147/IJGM.S32344
Abstract: emiology, clinical, immune, and molecular profiles of microsporidiosis and cryptosporidiosis among HIV/AIDS patients Original Research (1567) Total Article Views Authors: Wumba R, Longo-Mbenza B, Menotti J, Mandina M, Kintoki F, Situakibanza NH, Kakicha MK, Zanga J, Mbanzulu-Makola K, Nseka T, Mukendi JP, Kendjo E, Sala J, Thellier M Published Date July 2012 Volume 2012:5 Pages 603 - 611 DOI: http://dx.doi.org/10.2147/IJGM.S32344 Received: 28 March 2012 Accepted: 12 April 2012 Published: 19 July 2012 Roger Wumba,1 Benjamin Longo-Mbenza,2 Jean Menotti,3,4 Madone Mandina,5 Fabien Kintoki,5 Nani Hippolyte Situakibanza,1,5 Marie Kapepela Kakicha,6 Josue Zanga,1 Kennedy Mbanzulu-Makola,1 Tommy Nseka,1 Jean Pierre Mukendi,1 Eric Kendjo,7 Jean Sala,1 Marc Thellier7,8 1Department of Tropical Medicine, Infectious and Parasitic Diseases, Department of Parasitology, University Clinic of Kinshasa, Faculty of Medicine, University of Kinshasa, Kinshasa, Congo; 2Faculty of Health Sciences, Walter Sisulu University, Eastern Cape, South Africa; 3Laboratory of Parasitology and Mycology, Saint-Louis Hospital, Public Assistance-Hospitals of Paris, Paris, France; 4Faculty of Medicine, Lariboisière-Saint-Louis, University of Paris VII, Paris, France; 5Department of Internal Medicine, University Clinic of Kinshasa, Faculty of Medicine, University of Kinshasa, Kinshasa, Congo; 6Department of Pediatrics, University Clinic of Kinshasa, Faculty of Medicine, University of Kinshasa, Kinshasa, Congo; 7National Center for Malaria Research, AP-HP, CHU Pitie Salpêtrière, Paris, France; 8Laboratory of Parasitology and Mycology, Pitié Salpêtrière Hospital, Public Assistance-Hospitals of Paris, Pierre and Marie Curie University, Paris, France Background: The objective of this study was to determine the prevalence of intestinal parasites, with special emphasis on microsporidia and Cryptosporidium, as well as their association with human immunodeficiency virus (HIV) symptoms, risk factors, and other digestive parasites. We also wish to determine the molecular biology definitions of the species and genotypes of microsporidia and Cryptosporidium in HIV patients. Methods: In this cross-sectional study, carried out in Kinshasa, Democratic Republic of the Congo, stool samples were collected from 242 HIV patients (87 men and 155 women) with referred symptoms and risk factors for opportunistic intestinal parasites. The analysis of feces specimen were performed using Ziehl–Neelsen stainings, real-time polymerase chain reaction (PCR), immunofluorescence indirect monoclonal antibody, nested PCR-restriction fragment length polymorphism, and PCR amplification and sequencing. Odds ratio (OR) and 95% confidence intervals were used to quantify the risk. Results: Of the 242 HIV patients, 7.8%, 0.4%, 5.4%, 0.4%, 2%, 10.6%, and 2.8% had Enterocytozoon bieneusi, Encephalitozoon intestinalis, Cryptosporidium spp., Isospora belli, pathogenic intestinal protozoa, nonpathogenic intestinal protozoa, and hel
High-Resolution Microendoscopy for the Detection of Cervical Neoplasia in Low-Resource Settings
Mary K. Quinn, Tefo C. Bubi, Mark C. Pierce, Mukendi K. Kayembe, Doreen Ramogola-Masire, Rebecca Richards-Kortum
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0044924
Abstract: Cervical cancer is the second leading cause of cancer death among women in developing countries. Developing countries often lack infrastructure, cytotechnologists, and pathologists necessary to implement current screening tools. Due to their low cost and ease of interpretation at the point-of-care, optical imaging technologies may serve as an appropriate solution for cervical cancer screening in low resource settings. We have developed a high-resolution optical imaging system, the High Resolution Microendoscope (HRME), which can be used to interrogate clinically suspicious areas with subcellular spatial resolution, revealing changes in nuclear to cytoplasmic area ratio. In this pilot study carried out at the women's clinic of Princess Marina Hospital in Botswana, 52 unique sites were imaged in 26 patients, and the results were compared to histopathology as a reference standard. Quantitative high resolution imaging achieved a sensitivity and specificity of 86% and 87%, respectively, in differentiating neoplastic (≥CIN 2) tissue from non-neoplastic tissue. These results suggest the potential promise of HRME to assist in the detection of cervical neoplasia in low-resource settings.
Blood Pressure Patterns and Factors Associated with Relative Hypertension among Steady State Sickle Cell Disease Patients in Kinshasa, Democratic Republic of the Congo: A Cross-Sectional Study  [PDF]
P. I. Mboliasa, F. B. Lepira, J. R. Makulo, A. Nkodila, E. K. Sumaili, J. B. Bukabau, V. M. Mokoli, A. L. Longo, C. V. Zinga, F. M. P. Kanjingulu, Y. M. Nlandu, Y. M. Engole, M. M. Mukendi, E. M. Kadima, C. K. Ilunga, P. M. Ekulu, N. M. N. Nseka
World Journal of Cardiovascular Diseases (WJCD) , 2018, DOI: 10.4236/wjcd.2018.83021
Abstract: Background: Although systemic hypertension is rarely seen in steady state sickle cell disease (SCD), relative hypertension has been reported to be associated with an increased risk of cardiovascular and renal complications. Objective: To determine the prevalence of BP patterns and assess factors associated with relative hypertension insickle cell anemia (SCA) adult patients. Methods: Clinical data and office BP were obtained from 103 consecutive steady-state SCA adult patients (mean age 26 ± 7.9 years, 66% females, 22.3% on hydroxyurea) attending four healthcare centers providing SCD-specific care in Kinshasa. Seated BP was measured using an automated electronic device. Three consecutive blood pressure measurements were taken with 2 minutes interval between readings and the average of the 2 last readings was considered for the analyses. Normal BP, relative hypertension and systemic hypertension were defined as BP < 120/70 mmHg, 120 - 139/70 - 89 mmHg and ≥140/90 mmHg, respectively. Results: Normal BP, relative hypertension and systemic hypertension were observed in 56 (54%), 43(42%) and 4 (4%) of SCA patients, respectively. In multivariate analysis, factors associated with relative hypertension were leg ulcer (aOR 2.05; 95%CI 1.77 -
Effect of Heat Treatment Processes on the Mechanical Properties of Medium Carbon Steel  [PDF]
T. Senthilkumar, T. K. Ajiboye
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2012, DOI: 10.4236/jmmce.2012.112011
Abstract: The importance of various form of heat treatment operations on medium carbon steel in order to forester the problem that may arise in making a wrong choice of these steel materials or faulty heat treatment operations which may give rise to serious disruption in terms of human safety, higher cost and untimely failure of the machine components is of great concern. The mechanical properties such as ductility, toughness, strength, hardness and tensile strength can easily be modified by heat treating the medium carbon steel to suit a particular design purpose. Tensile specimens were produced from medium carbon steel and were subjected to various forms of heat treatment processes like annealing, normalizing, hardening and tempering. The stiffness, ductility, ultimate tensile strength, yield strength and hardness of the heat treated samples were observed from their stress-strain curve. The value of the yield strength (σy) was observed to be higher for the tempered specimen possibly as a result of the grain re-arrangement, followed by the hardened, normalized and annealed specimens. The value of the ultimate tensile strength (σu) were also observed to be in the order; hardened> tempered>normalized>annealed.
Data mining and networks neuronal: Extracting knowledge from high pressure data patients
Mbuyi Mukendi Eugandegrave;ne,Kafunda Katalayi Pierre,Mbuyi Badibanga Steve,Mbuyi Mukendi Didier
International Journal of Computer Science Issues , 2012,
Abstract: Data mining is a set of methods and techniques for exploring and analyzing automatically or semi-automatically databases in order to detect rules, associations, unknown or hidden trends, specific structures that restore most of the useful information while reducing the amount of data.This is a process of extracting valid and tractable knowledge from large amount of data.In this paper, we present a contribution on the extraction of useful knowledge from databases on patients with high blood pressure from one of the hospital in Kinshasa (RD Congo), using multi-layerneural networks.
Strength Characterization of E-glass Fiber Reinforced Epoxy Composites with Filler Materials  [PDF]
K. Devendra, T. Rangaswamy
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2013, DOI: 10.4236/jmmce.2013.16054
Abstract: In this research work, an investigation was made on the mechanical properties of E-glass fiber reinforced epoxy composites filled by various filler materials. Composites filled with varying concentrations of fly ash, aluminum oxide (Al2O3), magnesium hydroxide (Mg(OH)2) and hematite powder were fabricated by standard method and the mechanical properties such as ultimate tensile strength, impact strength and hardness of the fabricated composites were studied. The test results show that composites filled by 10% volume Mg(OH)2 exhibited maximum ultimate tensile strength and hardness. Fly ash filled composites exhibited maximum impact strength.
Analysis of the Machining Characteristics on Surface Roughness of a Hybrid Aluminium Metal Matrix Composite (Al6061-SiC-Al2O3)  [PDF]
T. Sasimurugan, K. Palanikumar
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2011, DOI: 10.4236/jmmce.2011.1013094
Abstract: Aluminium metal matrix composites are finding increased applications in many areas. Adding of the third element to the metal matrix make the composite hybrid. This paper presents the study on the surface roughness characteristics of a hybrid aluminium metal matrix (Al6061-SiC-Al2O3) composites. The experimental studies were carried out on a lathe. The composites were prepared using the liquid metallurgy technique, in which 3, 6 and 9 wt % of particulates SiC and Al2O3 were dispersed in the base matrix. The obtained cast composites were carefully machined. The characteristics that influence the surface roughness such as feed rate, depth of cut and cutting speed were studied, which made the analysis come to a conclusion that the surface roughness is increases with the increase of feed rate and it reduces the surface roughness with the increase of cutting speed.
Practical Implementation of Embedded Controlled Reduced Switch Z-Source Inverter-Fed Induction Motor Drive  [PDF]
K. Srinivasan, T. Vijayakumar
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.79190
Abstract: A cost-effective component minimized embedded controlled Z-source inverter for induction motor drive is presented. The proposed topology combines the advantages of a traditional four-switch three-phase inverter with the advantages of the z impedance network (two inductors in series and two X connected capacitors). This new topology, besides the self-boost property, has low switch count and it can operate as a buck-boost inverter. As a result, the new embedded controlled reduced switch Z-source inverter system provides ride through capability during voltage sags, reduces line harmonics, improves power factor, reliability and extends output voltage range. Analysis, simulation and experiment result will be presented to demonstrate these new features.
Data Intelligent Low Power High Performance TCAM for IP-Address Lookup Table  [PDF]
K. Mathan, T. Ravichandran
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.711313
Abstract: This paper represents current research in low-power Very Large Scale Integration (VLSI) domain. Nowadays low power has become more sought research topic in electronic industry. Power dissipation is the most important area while designing the VLSI chip. Today almost all of the high speed switching devices include the Ternary Content Addressable Memory (TCAM) as one of the most important features. When a device consumes less power that becomes reliable and it would work with more efficiency. Complementary Metal Oxide Semiconductor (CMOS) technology is best known for low power consumption devices. This paper aims at designing a router application device which consumes less power and works more efficiently. Various strategies, methodologies and power management techniques for low power circuits and systems are discussed in this research. From this research the challenges could be developed that might be met while designing low power high performance circuit. This work aims at developing Data Aware AND-type match line architecture for TCAM. A TCAM macro of 256 × 128 was designed using Cadence Advanced Development Environment (ADE) with 90 nm technology file from Taiwan Semiconductor Manufacturing Company (TSMC). The
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