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Search Results: 1 - 10 of 8848 matches for " Syeda Sarah Abbas "
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Appraisal of Techniques, Investigation and Analysis of Vitamin (B7) Biotin  [PDF]
Safila Naveed, Fatima Qamar, Syeda Sarah Abbas, Syed Hameez Jawed, Wajiha Raza, Mahera Khan, Bushra Iqbal
Open Access Library Journal (OALib Journal) , 2015, DOI: 10.4236/oalib.1101894
Abstract: Biotin is also called vitamin B7, vitamin B8 or vitamin H. Biotin is a water soluble compound and is colorless in appearance. Overall eight different types of biotin exist but only Biotin-D occurs naturally with its complete vitamin activity. It is mainly synthesized by mold, algae, bacteria, yeast and some plant species. There are different methods used to find the vitamins in nutrients and samples. This article is composed of the comprehensive review of the competitive techniques and various methods for the assay of biotin. High-pressure liquid chromatographic (HPLC), microbiological analysis and HPLC producer are adopted for the determination of biotin. An optimal analytical condition of biotin determination was performed by the HPCL method. The statistical parameters of the HPLC methods were compared and reviewed with other determination.
Contemporary Trends in Novel Ophthalmic Drug Delivery System: An Overview  [PDF]
Safila Naveed, Sidra Farooq, Syeda Sarah Abbas, Syed Hameez Jawed, Fatima Qamar, Mirza Yasir Hussain, Iqra Ali
Open Access Library Journal (OALib Journal) , 2015, DOI: 10.4236/oalib.1101497
Abstract: One of the most challenging tasks faced by the pharmaceutical researchers is the ophthalmic drug delivery. Their aim is to obtain and maintain a therapeutic level at the site of action for prolonged period of time. Therefore, to sustain drug levels at the target site for a sufficient time, novel drug delivery techniques should be developed. Ophthalmic drug delivery has proved significant advancement for future point of view. This article evaluates a variety of novel systems for ophthalmic drug delivery.
Diuretic Effect of Cymbopogon jwarancusa after Single and Multiple Doses in Rats  [PDF]
Sarah Jameel Khan, Syeda Afroz, Rafeeq Alam Khan
Pharmacology & Pharmacy (PP) , 2018, DOI: 10.4236/pp.2018.97019
Abstract: Diuretics are efficaciously used in management of various clinical emergencies like hypertension, heart failure, cirrhosis, hypercalciuria, hematuria and nephrotic syndrome. Cymbopogon jwarancusa is an aromatic perennial grass used in both traditional and Unani system of medicine to eradicate diseases like colds, seasonal fever, asthma, tuberculosis, rheumatic pain, back pain, toothache and nervous disorders. C. jwarancusa essential oils are used in perfumery, soap, detergents, medicines and pharmaceutical industry. Monoterpenes and sesquiterpenes constitute the highest composition in essential oil of C. jwarancusa. The present was designed to compare the diuretic activity of C. jwarancusa after single and multi-doses. Furosemide (20 mg/kg) was used as reference drug and 10% DMSO was used as vehicle. Diuretic activity was noticed by measuring urine volume and calculating diuretic and Lipchitz values. Maximum diuretic response was observed at 500 mg/kg of extract after both single and multi-dose administration. On basis of results it may be concluded that C. jwarancusa may be used as diuretic agent.
Adjuvant treatment for high risk melanoma. Where are we now?
Anand Sharma,Tahir Abbas,Sarah Gwynne
Oncology Reviews , 2011, DOI: 10.4081/109
Abstract: The survival rate for stage 3 and 4 melanoma is very poor. In the absence of effective treatments for metastatic disease focus has shifted to the adjuvant setting. While we are now able to identify those who are at high risk of recurrence the role of adjuvant systemic treatment in these individuals is still undefined. This is partly due to the lack of effective treatments, despite the advances in the understanding of the biology of melanoma and the natural history of the disease process. Of the various treatments studied in the adjuvant setting only interferons and vaccines have been shown to affect the clinical outcome but no agent has been accepted as a standard, with differences in practice between the US and Europe. In this review article we will report what is known at this time about the different agents studied in the adjuvant setting and refer to some new areas of research that may play a bigger role in the future management of melanoma.
Pancreatic Endocrine and Exocrine Function in Children following Near-Total Pancreatectomy for Diffuse Congenital Hyperinsulinism
Ved Bhushan Arya, Senthil Senniappan, Huseyin Demirbilek, Syeda Alam, Sarah E. Flanagan, Sian Ellard, Khalid Hussain
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0098054
Abstract: Context Congenital hyperinsulinism (CHI), the commonest cause of persistent hypoglycaemia, has two main histological subtypes: diffuse and focal. Diffuse CHI, if medically unresponsive, is managed with near-total pancreatectomy. Post-pancreatectomy, in addition to persistent hypoglycaemia, there is a very high risk of diabetes mellitus and pancreatic exocrine insufficiency. Setting International referral centre for the management of CHI. Patients Medically unresponsive diffuse CHI patients managed with near-total pancreatectomy between 1994 and 2012. Intervention Near-total pancreatectomy. Main Outcome Measures Persistent hypoglycaemia post near-total pancreatectomy, insulin-dependent diabetes mellitus, clinical and biochemical (faecal elastase 1) pancreatic exocrine insufficiency. Results Of more than 300 patients with CHI managed during this time period, 45 children had medically unresponsive diffuse disease and were managed with near-total pancreatectomy. After near-total pancreatectomy, 60% of children had persistent hypoglycaemia requiring medical interventions. The incidence of insulin dependent diabetes mellitus was 96% at 11 years after surgery. Thirty-two patients (72%) had biochemical evidence of severe pancreatic exocrine insufficiency (Faecal elastase 1<100 μg/g). Clinical exocrine insufficiency was observed in 22 (49%) patients. No statistically significant difference in weight and height standard deviation score (SDS) was found between untreated subclinical pancreatic exocrine insufficiency patients and treated clinical pancreatic exocrine insufficiency patients. Conclusions The outcome of diffuse CHI patients after near-total pancreatectomy is very unsatisfactory. The incidence of persistent hypoglycaemia and insulin-dependent diabetes mellitus is very high. The presence of clinical rather than biochemical pancreatic exocrine insufficiency should inform decisions about pancreatic enzyme supplementation.
Role of mycorrhiza to reduce heavy metal stress  [PDF]
Syeda Asma Bano, Darima Ashfaq
Natural Science (NS) , 2013, DOI: 10.4236/ns.2013.512A003
Abstract:

Plants have a system of antioxidant enzymes, which helps to alleviate the effects of various types of stresses. Heavy metals like Cadmium and lead are tolerable for plants to certain extent. The antioxidant enzymes do not function properly at higher concentrations of Cadmium, lead and some other heavy metals. The activities of antioxidant enzymes are reduced due to reactive oxygen species produced as a result of heavy metal stress. The catalase activity was directly inhibited by O2- (Kono and Fridovich, 1982). These ROS are O2-, H2O2, and -OH which can react with many other biomolecules. Several metallic ions are produced by radical displacement reactions. These metallic ions inhibit the activity of antioxidant enzymes. Hence, enzymic antioxidant defense system of plants is affected and adversely inhibits plant growth and productivity. Mycorrhizal fungi are important in phytostabilization of toxic heavy metals. Plants having mycorrhizal association accumulate metallic pollutants by storing these heavy metals in Vesicles as well as in fungal hyphae in their roots, hence these metallic pollutants are immobilized and do not inhibit the growth and uptake of phosphorus and some other micronutrients. Mycorrhizal fungi also release various organic acids which increase the solubilisation of insoluble phosphate compounds present in soil. The unavailable forms of phosphorus are converted into available forms as a result of organic acids produced by fungi. AM fungi release glomalins that are certain metal sorble glycoproteins which increase the immobilization of toxic metals. Another protein is metallothionine released by certain AM fungi, which also reduces the heavy metal toxicity in soil. Mycorrhizal fungi also induce resistance in plants against pathogens, drought and salinity stress. Investigation on heavy metal stress resistant genes in mycorrhizal plants can be very helpful for phytoremediation. This review focuses on the use of AM fungi for phytoremediation.

InSAR Observation for the Surface Displacements at Mt. Etna between 2003 and 2007  [PDF]
Syeda Sabikun Nahar, Arif Mahmud
International Journal of Geosciences (IJG) , 2015, DOI: 10.4236/ijg.2015.62010
Abstract: This research is mainly devoted to InSAR observations using Poly-Interferogram Rate and Time-series Estimator (π-rate) software to investigate continuous surface displacement at Mt. Etna (Sicily), Italy between 2003 and 2007. Using ascending and descending SAR images produced by European Space Agency’s ENVISAT, we generate a set of interferograms which are used to determinethe deformation history of Etna from 2003 to 2007. Using (π-rate), we can generate the InSARtime-series and ratemap while minimizing errors induced by the satellites orbit and atmosphericphase delays. During the period of 2003-2007, three separate eruptions were observed. In order to explain the deformation, we solve three displacement rate for 2003-2005, 2006 and 2007. As expected, the result suggests that displacement rates are not constant with respect to time. During 2006 the volcano appeared to switch from a period of deflation to a period of inflation. These results highlight the importance of InSAR for generating deformation time-series around Mt.Etna, and with the application of numerical models these results can be used to estimate theamount of magma moving in the subsurface.
Functional MRI and MR Spectroscopy Utilization in Jeddah Hospitals  [PDF]
Lamis K. Jada, Nabeel Mishah, Khalid Gh. Alsafi, Sarah Hagi, Mawya A. Khafaji, Hanan Y. Abbas, Saddig D. Jastaniah
Open Journal of Medical Imaging (OJMI) , 2015, DOI: 10.4236/ojmi.2015.53021
Abstract: Functional magnetic resonance imaging “fMRI” and magnetic resonance spectroscopy “MRS” are two crucial milestones that were introduced apart from one another into brain imaging and their implementation in major local cities is eventual step. Thus, the purpose of this study was to compare those techniques in terms of their clinical utilization in patient care delivery among the major governmental and private hospitals within Jeddah city. The study initially included eighteen hospitals to identify whether they were utilizing fMRI and MRS in their clinical practice. Out of the 18 hospitals under study only one hospital (5.6%) had both fMRI and MRS software; 7 (38.9%) had MRS but not fMRI; 4 (22.2%) did not have fMRI or MRS; and 6 (33.3%) hospitals had no MRI machine at all. Out of the eight hospitals applying MRS with one being excluded, the starting date of application was 2002 in 4 (57.1%) hospitals, 2004 in 1 (14.3%) hospital, and 2006 in 2 (28.6%) hospitals. The frequency of doing MRS was once a week in 2 (28.6%) hospitals, 2-3 cases/week in 3 (42.9%) hospitals, 5-10 cases/week in 1 (14.3%) hospital, and once every 6 months in 1 (14.3%) hospital. On the other hand, fMRI was applied only by one hospital starting in 2000 and was soon dismissed due to its time consumption and the inability of patients to accurately follow given instructions. It was concluded that MRS was more widely utilized compared to fMRI. Later on, a follow-up survey in the year of 2014 demonstrated that MRS has started to become a standard service in most hospitals whereas fMRI was still being unrecognized.
Effects of Storage Period and Temperature on Seed Viability of Wheat
Syeda Nasreen
Pakistan Journal of Biological Sciences , 1999,
Abstract: The study was conducted to investigate the effects of storage temperature and storage period on seed viability of a wheat variety, Rawal-87. The seed moisture content and seed viability were determined in control which were 8.0 per cent and 90 per cent respectively. The interaction among storage period and storage temperature was statistically significant. In wheat, the maximum seed viability was observed at -20 and 5 C after 12 months storage. A decline in germination percentage was observed at 50 C after 4 months. Germination per cent age was higher when petri dishes were used for germination tests. During germplasm storage of wheat, storage temperature and storage period play an important role.
Effects of Storage Temperature, Storage Period and Seed Moisture Content on Seed Viability of Mash Bean (Vigna mungo)
Syeda Nasreen
Pakistan Journal of Biological Sciences , 2000,
Abstract: The study was conducted to investigate the effects of different storage conditions on seed viability of mush bean, variety Mash-3. Three factors were included period and seed moisture content. Viability and Moisture content were determined in control which were 91.0 and 8.0 per cent respectively. The maximum germination percentage was observed in seeds with low moisture content. There was a decline in germination percentage after 90 days of storage at all temperatures in seeds with high and medium moisture contents. High moisture content and high temperature decreases germinability of seeds. The storage life of mashbean can be increased by lowering temperature and seed moisture content during storage.
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