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Escherichia coli Resistance to Ciprofloxacin in Acute Uncomplicated Pyelonephritis  [PDF]
Emad Abu Sitta, Nour Aljariri Alhesan, Babikir Kheiri, Sunil Badami, Farah Elounais, Omar Assassa, Maneesh Gaddam, Carlos Rios-Bedoya
Open Access Library Journal (OALib Journal) , 2017, DOI: 10.4236/oalib.1104043
Background: Severe acute uncomplicated pyelonephritis is an infection of the kidneys that usually have an ascending route and occur in presumably healthy urinary tract. The most common pathogen involved is E. coli. The Infectious Diseases Society of America (IDSA) has issued an updated guideline in 2010 suggesting IV quinolones to be considered in the initial empiric antimicrobial therapy giving known resistance of less than 10%. However, E. coli resistance to quinolones has been increasing, the recent data of E. coli, causing pyelonephritis, resistance is not known in the Midwest. Local hospital antibiogram for two years showed up to 22% resistance to ciprofloxacin among E. coli isolates. Methods: We conduct a retrospective non-concurrent cohort study in one teaching hospital in the Midwest, females who were admitted with severe acute uncomplicated pyelonephritis in a three years period were included. Patients with urinary tract obstruction, pregnancy, immuno-suppression, males, and indwelling Foley’s catheters were excluded. Data collected include causative pathogens and resistance to antibiotics were collected. Percentages, frequencies, and measures of central tendency and dispersion were calculated to describe the study sample Results: 73 patients were included in the final analysis. E. coli was the most common isolated pathogen (81%), followed by other enteric gram negative. E. coli resistance to ciprofloxacin was 13.5%, 37% to trimethoprim-sulfamethoxazole, and 5% to ceftriaxone. Conclusion: Ciprofloxacin should be avoided initially in treating severe acute uncomplicated pyelonephritis until culture results and sensitivity is available.
The study of the basis of women's rights from the point of view of the legal system of Islam and the West (View from feminism to human dignity)
Mohammad Ali Badami , Mohammad Mehdi Badami
International Journal of Nations Research , 2018, DOI: -
Abstract: Among the issue most widely discussed in today's society and dialogue is the question of women's rights. women's rights are human rights issues that all different cultures or different societies are involved with this issue. According to the process of thinking about women's rights in society certainly, there will be different attitudes in this area between people, because people's awareness of the rights of women often pushes mind toward democracy of the human rather than masculinity or femininity. By examining this issue From the perspective of the legal system of Islam and the West, the legal basis for women's rights based on human dignity can be realized which Western human rights worldwide has now turned its attention to it, However before the appearance of human rights, Western society follows this attitude on the basis of thinking to the ideas of feminism . Now with this comparative comparison we will realize that from fourteen centuries ago Islam puts its attention to the basis of human dignity for women's rights.
"Rate of Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum in Infertile Females and Control Group"
N Badami,MH Salari
Iranian Journal of Public Health , 2001,
Abstract: Infertility in famale is one of the most important sequela of genital infection with Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum. In the present study the frequency of these bacteries was studied in 125 infertile female by direct and indirect immunofluorscence tests and culture method and compared with 250 normal population. Mycoplasma hominis was isolated from 32 (35.6%) of infertile females compare with 18 (7.2%) of normal population. Ureaplasma urealyticum was isolated from 41 (32.8%) of infertile females compare to 48 (19.2%) of normal population. Chlamydia trachomatis was detected by direct IF in 11 (8.8%) of infertile and 2 (0.8%) control group. The antibody titer against D-K serotypes of Chlamydia trachomatis was also measured in both groups of infertile and normal population and a positive titer of 1/16 and above was detected in 26 (20.8%) of infertile cases and in 8 (3.2%) of control group. The rate of Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum in case and control groups was significant (respectively P<0.0001, P<0.0001, p= 0.0018).
"The rate of Chlamydia Trachomatis, Mycoplasma Hominis and Ureaplasma Urealyticum in females with habitual abortion and its comparison with control group "
Salari MH,Badami N
Acta Medica Iranica , 2002,
Abstract: Females abortion is one of the most important sequela of genital infection with chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum.In this study frequency of Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum was studied in 125 females with habitual abortion by direct and indirect immunofluorescence tests and culture method and compared with 250 normal population. The results obtained were as follow: Mycoplasma hominis was isolated from 18 (14.4%) females with habitual abortion and 18 (7.2%) normal population (P=0.0139). Ureaplasma urealyticum was isolated from 39(31.2%) females with habitual aboration and 48 (19.2%) normal population (P=0.0045). Chlamydia trachomatis was detected by direct immunofluorescence test in 9 (7.2%) of cases and 2 (0.8%) of control groups (P=0.0002). the antibody titer against D-K serotypes of Chlamydia trachomatis was also measured. The valuable titer of antibody (>1/16) was detected in 15 (12% of cases and 8 (3.2%) of control groups (P=0.0004).The results show that chlamydia trachomatis and Ureaplasma urealyticum may be responsible for some cases of abortion.
Macro to Micro Viewpoint of Climate Change - Linking Karnataka to Global Issue  [PDF]
Sunil Nautiyal
Natural Resources (NR) , 2011, DOI: 10.4236/nr.2011.21004
Abstract: A numerous studies have been done on climate change at regional, national and global levels. Several climate models have predicted the global scenarios for climate in different parts of the world. However, the significance and practical implementation of such models at local level yet to be validated. This is because those national or global models do not consider micro variables such as such as environmental resources for example ‘land availability, local climatic conditions, socioeconomic factors such as ‘labour and capital’, policy aspects such as ‘subsidies, nature conservation strategies’ and competition for labor and capital in relation of ‘national economy’. India, with a huge diversity in land, topography, climate and socioeconomic conditions, divided into 15 agro-ecological zones. Further, to help develop location specific research and development strategies at the micro level, a total of 127 sub-zones (agro-climatic sub regions) have been identified in India. Therefore, research on climate change and its impact only at the regional or national level may not be a sound approach to provide solutions for adaptation to climate change at micro level. Thus the micro-level research needs to be undertaken that might help us understand climate change impacts on the landscape i.e. biodiversity, health, natural resource management, land use and land cover development, adaptation and the development of socio-ecological systems. The concepts presented in this article should provide the basis for a discussion on decision-making issues among multidisciplinary experts with regard to climate change and sustainable development within complex environments.
Antimicrobial, heavy metal resistance and plasmid profile of coliforms isolated from nosocomial infections in a hospital in Isfahan, Iran
Vajiheh Karbasizaed, Naser Badami, Giti Emtiazi
African Journal of Biotechnology , 2003,
Abstract: The antimicrobial, heavy metal resistance patterns and plasmid profiles of Coliforms (Enterobacteriacea) isolated from nosocomial infections and healthy human faeces were compared. Fifteen of the 25 isolates from nosocomial infections were identified as Escherichia coli, and remaining as Kelebsiella pneumoniae. Seventy two percent of the strains isolated from nosocomial infections possess multiple resistance to antibiotics compared to 45% of strains from healthy human faeces. The difference between minimal inhibitory concentration (MIC) values of strains from clinical cases and from faeces for four heavy metals (Hg, Cu, Pb, Cd) was not significant. However most strains isolated from hospital were more tolerant to heavy metal than those from healthy persons. There was no consistent relationship between plasmid profile group and antimicrobial resistance pattern, although a conjugative plasmid (>56.4 kb) encoding resistance to heavy metals and antibiotics was recovered from eight of the strains isolated from nosocomial infections. The results indicate multidrug-resistance coliforms as a potential cause of nosocomial infection in this region.
Tandem synthesis of novel 4-(azidocarbonyl)phenylazide from 3-(4-hydrazinocarbonyl)phenylsydnone and its chemoselective 1,3 dipolar cycloaddition reaction and Curtius rearrangement
Prashant R. Latthe,Bharati V. Badami
Organic Communications , 2011,
Abstract: C The 4-(azidocarbonyl)phenylazide 3 obtained from 4-(hydrazinocarbonyl) phenylsydnone 1 by tandem hydrolysis – diazotisation, is used as the key intermediate for the chemoselective one-pot 1,3- dipolar cycloaddition reaction with dimethylacetylene dicarboxylate (DMAD) along with Curtius rearrangement affording the carbamates 5a-c and the isocyanate 6. These compounds were further used as building blocks for the triheterocyclic carbamates 9a-c and 10a-c and 4- triazolophenylaryl ureas 7a-f. The ethyl carbamate derivative 5a exhibited antibacterial inhibition selectively against B.subtilis almost one and half times more than Norfloxacin while compounds 5a, 7b and 10c were as active as Griseofulvin against A.flavus
A new Synthesis of 3-arylpropenoic acids and 5-phenyl-2,4-pentadienoic acid from 4-acetyl-3-arylsydnones and arylaldehydes
R. Sanyal,Bharati V.Badami
Organic Communications , 2009,
Abstract: The 3-aryl-(4-cinnamoyl)sydnones 3a-l obtained from 4-acetyl-3-arylsydnones 2a-d and arylaldehydes, on hydrolysis with conc.H 2SO 4 under mild conditions yielded the 3-arylpropenoic acids 4a-c. Reusable 3-arylsydnones 1a-d were also recovered. This simple and practical synthesis was also applied to the preparation of 5-phenyl-2,4-pentadienoic acid 6.
Hepatoprotective Activity of Methanolic Extract of Oldenlandia herbacea Against D - Galactosamine Induced Rats
S Pandian,S Badami,M Shankar
International Journal of Applied Research in Natural Products , 2013,
Abstract: Summary: The present study is to evaluate the hepatoprotective activity of methanolic extract of Oldenlandia herbacea against D - Galactosamine/ Lipopolysacharide (D - GalN) induced rats. Hepatoprotective activity was performed by using the toxicant D-GalN (200 mg/kg) in Wistar rats. Methanolic extract of the whole plant of O. herbacea was administered orally at doses of 100 and 200 mg/kg/day for 8 days. Silymarin (100 mg/kg) was used as standard drug. Levels of various biochemical parameters in serum the histopathology of liver were assessed to study the hepatoprotective effect of the extract. The extract showed significant reduction in the D-GalN induced liver damage and symptoms of liver injury by restoration of the deviated levels of various biochemical parameters of liver which were observed in toxic control group. Histopathology of the liver sections confirmed that the extract prevented hepatic damage induced by D-GalN. The methanolic extract of O. herbacea showed significant hepatoprotective activity. Industrial relevance: The herbal drugs continue to serve as an important source of conventional therapies for diverse disease conditions and reactions. This is a preliminary study and this will support us to isolate the biological active phyto-constituents for treating liver disorders. This study will help in discovering a new or active phytochemicals and thus create a novel hepatoprotective moiety with less adverse effect for the betterment of the human society and more affordable and accessible to the users. Keywords: Oldenlandia herbacea; D-galactosamine; Hepatoprotective activity; Silymarin.
A Novel Strategy Selection Method for Multi-Objective Clustering Algorithms Using Game Theory
Mahsa Badami,Ali Hamzeh,Sattar Hashemi
International Journal of Computer Science Issues , 2012,
Abstract: The most important factors which contribute to the efficiency of game-theoretical algorithms are time and game complexity. In this study, we have offered an elegant method to deal with high complexity of game theoretic multi-objective clustering methods in large-sized data sets. Here, we have developed a method which selects a subset of strategies from strategies profile for each player. In this case, the size of payoff matrices reduces significantly which has a remarkable impact on time complexity. Therefore, practical problems with more data are tractable with less computational complexity. Although strategies set may grow with increasing the number of data points, the presented model of strategy selection reduces the strategy space, considerably, where clusters are subdivided into several sub-clusters in each local game. The remarkable results demonstrate the efficiency of the presented approach in reducing computational complexity of the problem of concern.
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