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Search Results: 1 - 10 of 27495 matches for " Sung-Doo Lee "
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Stability Enhancement in HVDC System with STATCOM  [PDF]
Chan-Ki Kim, Jin-Young Kim, Sung-Doo Lee, Eung-Bo Sim
Engineering (ENG) , 2011, DOI: 10.4236/eng.2011.311133
Abstract: This paper deals with the stability problem at the inverter end of a HVDC link with STATCOM (Static Compensator), when connected to a weak AC system which has the stability enhancement for power instability and commutation failures. The HVDC stability problem is tackled with a STATCOM which not only provides a rapid recovery from power, harmonic stability and commutation failures but also offers a lower cost filter design for the HVDC system. PSCAD/EMTDC simulations are presented to demonstrate the robust performance and to validate the proposed topology.
The Outcome of the Chemotherapy and Oncothermia for Far Advanced Adenocarcinoma of the Lung: Case Reports of Four Patients  [PDF]
Doo Yun Lee, Joon Seok Park, Hae Chul Jung, Eun Seol Byun, Seok Jin Haam, Sung Soo Lee
Advances in Lung Cancer (ALC) , 2015, DOI: 10.4236/alc.2015.41001
Abstract:

Lung cancer is one of the most aggressive and lethal form of cancers. Patients with far advanced lung cancer are treated by chemotherapy with or without radiotherapy. However, median survival of these patients is less than 6 months. To increase survival and quality of life for these patients, various forms of complementary treatments have been tried in clinical practices, and oncothermia is supposed to be one of the promising candidates. From May 2008 to November 2013, 4 patients with far advanced lung adenocarcinoma (stages IIIB and IV) were treated with oncothermia in addition to conventional chemotherapy at Gangnam Severance Hospital and Bundang CHA Hospital. All these patients have survived for more than 2 years.

Magnesium citrate with a single dose of sodium phosphate for colonoscopy bowel preparation
Yong Sung Choi, Jung Pil Suh, Jong Kyu Kim, In Taek Lee, Eui Gon Youk, Doo Seok Lee, Do Sun Kim, Doo Han Lee
World Journal of Gastroenterology , 2011,
Abstract: AIM: To evaluate the efficacy and acceptability of magnesium citrate and a single dose of oral sodium phosphate (45 mL) solution for morning colonoscopy bowel preparation.METHODS: A total of 159 patients were randomly assigned to receive two split doses of 90 mg of sodium phosphate (Group I, n = 79) or magnesium citrate (250 mL, the day before the procedure) followed by 45 mL of sodium phosphate (the day of procedure, Group II, n = 80). The quality of bowel cleansing and the acceptability of each regimen were compared, including the satisfaction, taste, willing to repeat and adverse effects of each regimen.RESULTS: The quality of bowel cleansing of Group II was as good as that of Group I (An Aronchick scale score of good or excellent: 70.9% vs 81.0%, respectively, P = 0.34; the Ottawa system score: 4.4 ± 2.6 vs 3.8 ± 3.0, respectively, P = 0.76). There was no statistically significant difference between both groups with regard to acceptability, including the satisfaction, taste and willingness to repeat the regimen. A significantly greater number of older patients (over 65 years old) in Group II graded the overall satisfaction as satisfactory (48.1% vs 78.1%, respectively; Group I vs Group II, P = 0.01). There were no significant adverse reactions.CONCLUSION: Magnesium citrate and a single dose of sodium phosphate was as effective and tolerable as the conventional sodium phosphate regimen and is a satisfactory option.
Quantitative Analysis and Efficient Surface Modification of Silica Nanoparticles
Hak-Sung Jung,Doo-Sik Moon,Jin-Kyu Lee
Journal of Nanomaterials , 2012, DOI: 10.1155/2012/593471
Abstract: Aminofunctional trialkoxysilanes such as aminopropyltrimethoxysilane (APTMS) and (3-trimethoxysilylpropyl)diethylenetriamine (DETAS) were employed as a surface modification molecule for generating monolayer modification on the surface of silica (SiO2) nanoparticles. We were able to quantitatively analyze the number of amine functional groups on the modified SiO2 nanoparticles by acid-base back titration method and determine the effective number of amine functional groups for the successive chemical reaction by absorption measurements after treating with fluorescent rhodamine B isothiocyanate (RITC) molecules. The numbers of amine sites measured by back titration were 2.7 and 7.7 ea/nm2 for SiO2-APTMS and SiO2-DETAS, respectively, while the numbers of effective amine sites measured by absorption calibration were about one fifth of the total amine sites, namely, 0.44 and 1.3 ea/nm2 for SiO2-APTMS(RITC) and SiO2-DETAS(RITC), respectively. Furthermore, it was confirmed that the reactivity of amino groups on the surface-modified silica nanoparticles could be maintained in ethanol for more than 1.5 months without showing any significant differences in the reactivity.
Estimating Crown Variables of Individual Trees Using Airborne and Terrestrial Laser Scanners
Sung-Eun Jung,Doo-Ahn Kwak,Taejin Park,Woo-Kyun Lee,Seongjin Yoo
Remote Sensing , 2011, DOI: 10.3390/rs3112346
Abstract: In this study, individual tree height (TH), crown base height (CBH), crown area (CA) and crown volume (CV), which were considered as essential parameters for individual stem volume and biomass estimation, were estimated by both an airborne laser scanner (ALS) and a terrestrial laser scanner (TLS). These ALS- and TLS-derived tree parameters were compared because TLS has been introduced as an instrument to measure objects more precisely. ALS-estimated TH was extracted from the highest value within a crown boundary delineated with the crown height model (CHM). The ALS-derived CBH of individual trees was estimated by k-means clustering method using the ALS data within the boundary. The ALS-derived CA was calculated simply with the crown boundary, after which CV was computed automatically using the crown geometric volume (CGV). On the other hand, all TLS-derived parameters were detected manually and precisely except the TLS-derived CGV. As a result, the ALS-extracted TH, CA, and CGV values were underestimated whereas CBH was overestimated when compared with the TLS-derived parameters. The coefficients of determination (R2) from the regression analysis between the ALS and TLS estimations were approximately 0.94, 0.75, 0.69 and 0.58, and root mean square errors (RMSEs) were approximately 0.0184 m, 0.4929 m, 2.3216 m2 and 13.2087 m3 for TH, CBH, CA and CGV, respectively. Thereby, the error rate decreased to 0.0089, 0.0727 and 0.0875 for TH, CA and CGV via the combination of ALS and TLS?data.
Quick Local Repair Scheme using Adaptive Promiscuous Mode in Mobile Ad Hoc Networks
Joo-Sang Youn,Ji-Hoon Lee,Doo-Hyun Sung,Chul-Hee Kang
Journal of Networks , 2006, DOI: 10.4304/jnw.1.1.1-11
Abstract: In mobile ad hoc networks (MANETs), there is frequently disconnected a route consisting of multi- hop from a source to a destination because of the dynamic nature such as the topology change caused by nodes’ mobility. To overcome this situation, existing routing protocols for MANETs have performed route repair scheme to repair the disconnected route. However, existing reactive routing protocols have the problem which is that a source node unnecessarily performs re-discovers the whole path when just one node moves, even if the rest of path needs not to be re-arranged. Therefore, the time for re-discovery of the whole path may often take too long. To solve the problem, we propose a new local repair scheme using promiscuous mode. Our scheme is mainly composed of two parts: adaptive promiscuous mode and quick local repair scheme. Adaptive promiscuous mode is to repeat the switching processes between promiscuous mode and nonpromiscuous mode to overcome energy limit caused by using promiscuous mode in overall time and quick local repair scheme is to fast perform the local re-route discovery process with the information of the active connection in the local area acquired by promiscuous mode. With simulation in the various number of connection, We demonstrate the better network performances achieved with the proposed schemes as compared with AODV as reference model that do not provide local repair scheme.
Mitochondrial Peroxiredoxin III is a Potential Target for Cancer Therapy
In-Sung Song,Hyoung-Kyu Kim,Seung-Hun Jeong,Sung-Ryul Lee,Nari Kim,Byoung Doo Rhee,Kyung Soo Ko,Jin Han
International Journal of Molecular Sciences , 2011, DOI: 10.3390/ijms12107163
Abstract: Mitochondria are involved either directly or indirectly in oncogenesis and the alteration of metabolism in cancer cells. Cancer cells contain large numbers of abnormal mitochondria and produce large amounts of reactive oxygen species (ROS). Oxidative stress is caused by an imbalance between the production of ROS and the antioxidant capacity of the cell. Several cancer therapies, such as chemotherapeutic drugs and radiation, disrupt mitochondrial homeostasis and release cytochrome c, leading to apoptosome formation, which activates the intrinsic pathway. This is modulated by the extent of mitochondrial oxidative stress. The peroxiredoxin (Prx) system is a cellular defense system against oxidative stress, and mitochondria in cancer cells are known to contain high levels of Prx III. Here, we review accumulating evidence suggesting that mitochondrial oxidative stress is involved in cancer, and discuss the role of the mitochondrial Prx III antioxidant system as a potential target for cancer therapy. We hope that this review will provide the basis for new strategic approaches in the development of effective cancer treatments.
Low Pulmonary Function in Individuals with Impaired Fasting Glucose: The 2007-2009 Korea National Health and Nutrition Examination Survey
Yun Jeong Lee, Na Kyung Kim, Ju Yean Yang, Jung Hyun Noh, Sung-Soon Lee, Kyung Soo Ko, Byoung Doo Rhee, Dong-Jun Kim
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0076244
Abstract: Objective To investigate the association between fasting plasma glucose level and pulmonary function. Research Design and Methods Nutritional information, pulmonary function data, and laboratory test data from 9,223 subjects from the fourth Korea National Health and Nutrition Examination Survey were examined. The participants were divided into five groups according to fasting plasma glucose (FPG) level: normal fasting glucose (NFG)1, FPG <90 mg/dl; NFG2, FPG 90-99 mg/dl; impaired fasting glucose (IFG)1: FPG 100-109 mg/dl; IFG2, FPG 110-125 mg/dl; and diabetes, FPG ≥126 mg/dl and/or current anti-diabetes medications. Results After adjustment for several variables, the percentage of predicted forced vital capacity(FVC%) decreased with increasing fasting plasma glucose level in both sexes[men: (mean ± SEM) 92.0±0.3 in NFG1; 91.9±0.3 in NFG2; 92.0±0.4 in IFG1; 90.2±0.7 in IFG2; and 89.9±0.5 in diabetes, P = 0.004; women: 93.7±0.3 in NFG1; 93.7±0.3 in NFG2; 93.1±0.5 in IFG1; 91.1±0.9 in IFG2; and 90.7±0.6 in diabetes, P<0.001]. A logistic regression analysis found that IFG2 and diabetes were independently associated with the lowest quintile of predicted FVC% (IFG2: odds ratio [95%CI], 1.50 [1.18-1.89], P = 0.001; diabetes: 1.56 [1.30-1.88], P<0.001) using NFG1 as a control. Conclusions The current data suggest that forced vital capacity may begin to decrease in the higher range of IFG.
Genetic diversity of a Korean echovirus 5 isolate and response of the strain to five antiviral drugs
Kwisung Park, Jaehyoung Song, Kyoungah Baek, Changgyun Lee, Donguk Kim, SamHyun Cho, JoonSoo Park, YoungJin Choi, Byunghak Kang, Hwajung Choi, Doo-Sung Cheon
Virology Journal , 2011, DOI: 10.1186/1743-422x-8-79
Abstract: Human enteroviruses (HEV) are RNA viruses from the Picornaviridae family. The 80 immunologically-distinct serotypes that are known to cause infections in humans can be grouped as follows: polioviruses (PV), echoviruses (ECV), coxsackieviruses A (CVA), coxsackieviruses B (CVB), and enterovirus (EV) types 68-71. These viruses are also classified genetically into five species (HEV-A to HEV-D and PVs). HEV-B group containing ECV 5 are CBV 1 to 6, CVA9, ECV 1 to ECV 7, ECV 9, ECV 11 to ECV 21, ECV 24 to ECV 27, ECV 29 to 33, EV 69, EV 73 [1-5].ECV cause the same types of infections in humans as the CVB group, but are given a distinct classification primarily because they lack pathogenicity in newborn mice [6]. There are, however, strains of ECV that are pathogenic in mice [7]. ECV 5 infections have been associated with a wide variety of neurological and exanthematic diseases. The prototype strain of ECV 5 was isolated from a patient with aseptic meningitis and was later grouped as the fifth enterovirus serotype [8]. An outbreak of aseptic meningitis caused by ECV 5 occurred in Korea in 2006, marking the first time that ECV 5 had been identified in the country since enterovirus surveillance began in 1993 [9].The ECV 5 genome contains approximately 7,500 nucleotide-long single-stranded RNA molecules with polarity and carries a small viral peptide (VPg) covalently attached to its 5' end. The 5' untranslated region (UTR) of the RNA is approximately 700 nt in length and is unusually long compared with the homologous region of cellular mRNA. The internal ribosomal entry site (IRES) was discovered in the 5' UTR of the HEVs. In these viruses, the IRES can fold to be a functional secondary RNA structure and drive translation initiation [10]. The coding region encompasses a single open reading frame that encodes a polyprotein divided into three sub-regions, P1, P2, and P3. The P1 region encodes the genetic information of four structural proteins, VP4, VP2, VP3, and VP1. The non-st
Development of a highly sensitive real-time one step RT-PCR combined complementary locked primer technology and conjugated minor groove binder probe
JiYoung Hong, Byunghak Kang, Ahyoun Kim, Seoyeon Hwang, Jinhee Ahn, Sunhwa Lee, Jonghyen Kim, Jae-Hak Park, Doo-Sung Cheon
Virology Journal , 2011, DOI: 10.1186/1743-422x-8-330
Abstract: To develop a sensitive and reliable assay for routine laboratory diagnosis, we developed a real-time one step reverse transcription polymerase chain reaction (RT-PCR) assay with minor groove binder probes and primers modified with complementary locked primer technology (TMC-PCR). We checked the sensitivity of the developed assay by comparing it to a previously published TaqMan probe real-time one-step RT-PCR (TTN-PCR) procedure using enteroviral isolates, Enterovirus Proficiency panels from Quality Control on Molecular Diagnostics (QCMD-2007), and clinical specimens from patients with suspected EV infections.One hundred clinical specimens from 158 suspected viral meningitis cases were determined to be positive by the TMC-PCR assay (63.29%), whereas only 60 were found to be positive by the TTN-PCR assay (37.97%). The positive and negative agreements between the TMC-PCR and TTN-PCR assays were 100% and 59.2%, respectively.This data suggest that the TMC-PCR assay may be suitable for routine diagnostic screening from patient suspected EV infection.Enteroviruses (EVs) are among the most common and important viruses infecting humans. EVs are associated with diverse clinical syndromes, ranging from mild febrile illness to severe central nervous system diseases, such as aseptic meningitis and encephalitis, potentially leading to paralysis [1,2]. Neonates and young children are at the greatest risk of developing severe, and occasionally fatal, enteroviral infections [3,4]. Serotypes of EVs have traditionally been classified into echoviruses, coxsackieviruses, groups A and B, and polioviruses [5]. Currently, EV subtypes are divided into five species (human enteroviruses [HEV] A, B, C, D, and poliovirus) with differing molecular and biological characteristics [6]. Laboratory methods used for the diagnosis of enteroviral infection have changed substantially over time [7-9]. Initially, EVs were detected exclusively by cell culture and identified by neutralization [10]. In the mi
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