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Search Results: 1 - 10 of 27390 matches for " Sung Lee "
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Synthesis and Characterization of Carbon Nitride Films for Micro Humidity Sensors
Sung Pil Lee
Sensors , 2008, DOI: 10.3390/s8031508
Abstract: Nano-structured carbon nitride (CNx) films were synthesized by a reactive RFmagnetron sputtering system with a DC bias under various deposition conditions, and theirphysical and electrical properties were investigated with a view to using them for microhumidity sensors. The FTIR spectra of the deposited films showed a C=N stretching bandin the range of 1600~1700 ㎝-1, depending on the amount of nitrogen incorporation. Thecarbon nitride films deposited on the Si substrate had a nano-structured surfacemorphology with a grain size of about 20 nm, and their deposition rate was 1.5 μm/hr. Thesynthesized films had a high electrical resistivity in the range of 108 to 109 ω·cm,depending on the deposition conditions. The micro humidity sensors showed a goodlinearity and low hysteresis between 5 ~ 95 %RH.
Current implications of cyclophilins in human cancers
Jinhwa Lee, Sung Kim
Journal of Experimental & Clinical Cancer Research , 2010, DOI: 10.1186/1756-9966-29-97
Abstract: Cyclophilins (Cyps) were initially identified as biological receptors for the immunosuppressive drug cyclosporine A (CsA) approximately 25 years ago. Later, they were shown to have peptidyl-prolyl cis-trans isomerase (PPIase) enzymatic activity which catalyzes cis-trans isomerization of peptide bonds preceding proline [1-6]. Cyps also possess chaperone activities. These two functions allow Cyps to be involved in proper folding of proteins in combination with other proteins. Although CsA is an effective inhibitor of Cyps, immunosuppressive activity of CsA is not the result of inhibition of the Cyps' activities. Rather, the Cyp-CsA complex accidentally inhibits calcineurin activity and thereby suppresses T-cell proliferation by interfering with downstream signal transduction [7].Cyps are highly conserved from E. coli to humans throughout evolution. A total of 16 Cyp isoforms have been found in humans [8], but 7 major human Cyp isoforms, namely hCypA, hCypB, hCypC, hCypD, hCypE, hCyp40, and hCypNK [9], have been well characterized. They play diverse roles by localizing through unique domains for particular cellular compartments including the cytosol, endoplasmic reticulum (ER), mitochondria and nucleus. The clinical importance of Cyps has been implicated in diverse pathological conditions including HIV [10], hepatitis B and C viral infection, atherosclerosis [11,12], ER stress-related diseases such as diabetes, and neurodegenerative diseases. Cyps are also involved in normal cellular functions of muscle differentiation, detoxification of reactive oxygen species (ROS) [13], and immune response [14]. Their novel and unfamiliar nuclease activity similar to apoptotic endonucleases suggests a potential role in apoptotic DNA degradation. Overall roles of Cyps may encompass far more than already defined functions such as protein folding.CypA overexpression in diverse types of cancer has been recently reported by many research groups. Subsequently, overexpression of other Cyps
R-parity violating U(1)'-extended supersymmetric standard model
Lee, Hye-Sung
High Energy Physics - Phenomenology , 2008, DOI: 10.1142/S0217732308029939
Abstract: Supersymmetry is one of the best motivated new physics scenarios. To build a realistic supersymmetric standard model, however, a companion symmetry is necessary to address various issues. While R-parity is a popular candidate that can address the proton and dark matter issues simultaneously, it is not the only option for such a property. We review how a TeV scale U(1)' gauge symmetry can replace the R-parity. Discrete symmetries of the U(1)' can make the model still viable and attractive with distinguishable phenomenology. For instance, with a residual discrete symmetry of the U(1)', Z6 = B3 x U2, the proton can be protected by the baryon triality (B3) and a hidden sector dark matter candidate can be protected by the U-parity (U2).
Lightest U-parity Particle (LUP): a hidden sector dark matter candidate
Lee, Hye-Sung
High Energy Physics - Phenomenology , 2008, DOI: 10.1063/1.3052030
Abstract: We introduce a new dark matter candidate, the lightest U-parity particle (LUP). We suggest it as a good dark matter candidate especially in the R-parity violating supersymmetric model.
Dileptons and four leptons at Z' resonance in the early stage of the LHC
Lee, Hye-Sung
High Energy Physics - Phenomenology , 2008, DOI: 10.1016/j.physletb.2009.02.058
Abstract: The LHC era just began. The first discovery at the LHC experiment would be arguably a new resonance pole at TeV scale, if it exists. While the discovery of the Z' would be exciting by itself, it may also suggest what other new physics signals should be looked for while the LHC experiment is still at its early stage. We argue that the four lepton resonance at the Z' pole is a well-motivated and promising signal especially in supersymmetry framework, which can serve as a supersymmetry search scheme even in the early stage of the LHC experiment.
Suppression of Gate Oxide Degradation for MOS Devices Using Deuterium Ion Implantation Method
Jae-Sung Lee
Transactions on Electrical and Electronic Materials , 2012,
Abstract: This paper introduces a new method regarding deuterium incorporation in the gate dielectric including deuteriumimplantation and post-annealing at the back-end-of-the process line. The control device and the deuterium furnaceannealeddevice were also prepared for comparison with the implanted device. It was observed that deuteriumimplantation at a light dose of 1×1012 - 1×1014/cm2 at 30 keV reduced hot-carrier injection (HCI) degradation andnegative bias temperature instability (NBTI) within our device structure due to the reduction in oxide charge andinterface trap. Deuterium implantation provides a possible solution to enhance the bulk and interface reliabilities ofthe gate oxide under the electrical stress.
A Study on APEC’s Economic Cooperations under WTO
Jae-Sung Lee
International Journal of Business Administration , 2012, DOI: 10.5430/ijba.v3n6p55
Abstract: The changes in the international economic order are posing new challenges to the Asia-Pacific countries. To adapt to the WTO system and APEC, they must change their basic pattern of economic policy in relation to industry, finance and other areas, such as labor standards and competition policy. Government policy, however, is not the only, or even the major area facing new challenges. It will be the firms that will have to bear the brunt of the burden of adapting to the new environment. Moreover, the new global economic order no doubt means intensified competition, and it is the firms that compete. In order to survive in the new environment, they must be ready to undergo drastic changes, e.g. strategic alliances beyond national borders. This paper examines how to cooperate each other under APEC & WTO system to realize foreign open policy and to encourage the developing countries to be grow market orient.
Synthesis and Characterization of Carbon Nitride Films for Micro Humidity Sensors
Sung Pil Lee
Sensors , 2008,
Abstract: Nano-structured carbon nitride (CNx) films were synthesized by a reactive RFmagnetron sputtering system with a DC bias under various deposition conditions, and theirphysical and electrical properties were investigated with a view to using them for microhumidity sensors. The FTIR spectra of the deposited films showed a C=N stretching bandin the range of 1600~1700 £ -1, depending on the amount of nitrogen incorporation. Thecarbon nitride films deposited on the Si substrate had a nano-structured surfacemorphology with a grain size of about 20 nm, and their deposition rate was 1.5 m/hr. Thesynthesized films had a high electrical resistivity in the range of 108 to 109 ‰ ·cm,depending on the deposition conditions. The micro humidity sensors showed a goodlinearity and low hysteresis between 5 ~ 95 %RH.
Usability Testing for Developing Effective Interactive Multimedia Software: Concepts, Dimensions, and Procedures
Sung Heum Lee
Educational Technology & Society , 1999,
Abstract: Usability testing is a dynamic process that can be used throughout the process of developing interactive multimedia software. The purpose of usability testing is to find problems and make recommendations to improve the utility of a product during its design and development. For developing effective interactive multimedia software, dimensions of usability testing were classified into the general categories of: learnability; performance effectiveness; flexibility; error tolerance and system integrity; and user satisfaction. In the process of usability testing, evaluation experts consider the nature of users and tasks, tradeoffs supported by the iterative design paradigm, and real world constraints to effectively evaluate and improve interactive multimedia software. Different methods address different purposes and involve a combination of user and usability testing, however, usability practitioners follow the seven general procedures of usability testing for effective multimedia development. As the knowledge about usability testing grows, evaluation experts will be able to choose more effective and efficient methods and techniques that are appropriate to their goals.
Reverse Conservation Analysis Reveals the Specificity Determining Residues of Cytochrome P450 Family 2 (CYP 2)
Tai-Sung Lee
Evolutionary Bioinformatics , 2008,
Abstract: The concept of conservation of amino acids is widely used to identify important alignment positions of orthologs. The assumption is that important amino acid residues will be conserved in the protein family during the evolutionary process. For paralog alignment, on the other hand, the opposite concept can be used to identify residues that are responsible for specificity. Assuming that the function-specific or ligand-specific residue positions will have higher diversity since they are under evolutionary pressure to fit the target specificity, these function-specific or ligand-specific residues positions will have a lower degree of conservation than other positions in a highly conserved paralog alignment. This study assessed the ability of reverse conservation analysis to identify function-specific and ligand-specific residue positions in closely related paralog. Reverse conservation analysis of paralog alignments successfully identified all six previously reported substrate recognition sites (SRSs) in cytochrome P450 family 2 (CYP 2). Further analysis of each subfamily identified the specificity-determining residues (SDRs) that have been experimentally found. New potential SDRs were also predicted and await confirmation by further experiments or modeling calculations. This concept may be also applied to identify SDRs in other protein families.
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