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Search Results: 1 - 10 of 6352 matches for " Sung Hwan Jeong "
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Deformation Characteristics of Mono Strand Anchor Head  [PDF]
Sung Tae Kim, Jeong-Rae Cho, Keunhee Cho, Sung Yong Park, Young-Hwan Park
Engineering (ENG) , 2014, DOI: 10.4236/eng.2014.612072
Abstract: This paper investigates experimentally the deformation characteristics of the mono strand anchor head used in prestressed concrete bridge. Since the strains measurable in the anchor head are the axial and hoop strains, the deformation characteristics of the anchor head are examined by measuring these strains at various positions and according to the jacking force exerted on the pre-stressing strand. Moreover, the possibility to estimate the jacking force acting in the tendon based upon the measured strains and the corresponding error are evaluated.
Effective Use of Sugammadex for Incomplete Pyridostigmine Reversal of Muscle Relaxation by Rocuronium: A Case Report  [PDF]
Hee Jong Lee, Kyo Sang Kim, Ji Seon Jeong, Sung Hwan Choi, Kyu Nam Kim
Open Journal of Anesthesiology (OJAnes) , 2013, DOI: 10.4236/ojanes.2013.39083

Anticholinesterase does not allow adequate reversal of the deep neuromuscular blockade (NMB) achieved using high doses of relaxants. A 71-year-old female patient (weight 70 kg, height 169 cm) was scheduled for a transurethral resection of a bladder tumor under general anesthesia. We administered rocuronium 30 mg (0.43 mg/kg) for tracheal intubation due to an estimated short surgical time. During the operation, an additional rocuronium 10 mg was injected. The surgical procedure ended abruptly 10 minutes after receiving the last dose of rocuronium. At the end of surgery, the patient received pyridostigmine as a reversal. However, residual NMB persisted, and neuromuscular monitoring did not show the expected degree of recovery. Sugammadex 2 mg/kg was used, and the patient experienced complete reversal from NMB in just 2 min.

The Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Idiopathic Interstitisal Pneumonia  [PDF]
Ji Young Shin, Yu Jin Kim, Sun Young Kyung, Seung Yeon Ha, Sung Hwan Jeong
Open Journal of Respiratory Diseases (OJRD) , 2014, DOI: 10.4236/ojrd.2014.43014
Background: Idiopathic interstitial pneumonia is characterized by fibroblast proliferation and extracellular matrix (ECM) accumulation. Matrix metalloproteases (MMPs) and tissue inhibitors of metalloproteases (TIMPs) have been shown to regulate remodeling of the ECM, which indicates that they are important factors in the process of lung fibrosis. Therefore, we evaluated the expression of MMPs and TIMPs in tissues obtained from patients with idiopathic interstitial pneumonia and control tissues. Methods: Thirty-seven patients who were diagnosed with IIP (22: IPF, 13: NSIP, 2: COP) and 5 controls were enrolled in this study. The MMP-2 and -9 activity in lung tissue obtained from these patients was analyzed using gelatin zymography and the levels of TIMP-1 and -2 were measured by western blotting. We also evaluated the expression of MMP-2 and -9, as well as that of TIMP-1 and -2 in lung tissue using immunohistochemistry. Results: The levels of MMP-2 and MMP-9 were significantly increased in patients with IPF compared to those with NSIP and COP. The activities of TIMP-1 and -2 were also higher in patients with IPF than NSIP/COP patients and control subjects. There were no significant differences observed in the activities of MMPs and TIMPs obtained from patients with NSIP/COP and control subjects. The immunohistochemical analysis showed that TIMP-2 and MMP-2 were strongly stained at the fibroblasts of the fibroblastic foci in patients with IPF. Conclusions: These results suggest that over-expression of gelatinases and TIMPs in patients with IPF are important factors in the irreversible fibrosis that is associated with lung parenchyma.
First Record of a Snailfish, Careproctus notosaikaiensis (Scorpaeniformes: Liparidae) from Korea
Hwan-Sung Ji,Jeong-Ho Park,Tae-Woo Ban,Jin-Koo Kim
Animal Systematics, Evolution and Diversity , 2012, DOI: http://dx.doi.org/10.5635/ased.2012.28.4.308
Abstract: A single specimen (134.3 mm standard length) of a snailfish, Careproctus notosaikaiensis was collected from a fish trap in Goseong-gun, Gangwon-do, East Sea, Korea. It is characterized by having the teeth strongly trilobed; dorsal fin rays 52; anal fin rays 47; pectoral fin rays 35; caudal fin rays 10; vertebrae 58; ribs 2 pairs; cephalic pores, 2-6-7-2; gill slit extending to the fifth pectoral fin ray; chin pores paired and equal in size; dorsal and anal fins with distinct reddish margins. We describe this species as the first record to Korea, and proposed the new Korean name, “Dong-hae-bun-hong-ggom-chi” for this species.
Change in renal function after sodium phosphate preparation for screening colonoscopy
Dong Choon Seol, Sung Noh Hong, Jeong Hwan Kim, In Kyung Sung, Hyung Seok Park, Jung Hyun Lee, Chan Sup Shim
World Journal of Gastroenterology , 2010,
Abstract: AIM: To investigate the changes in renal function at 12-24 mo in patients following sodium phosphate (NaP) preparation for screening colonoscopy.METHODS: We carried out a retrospective study on the results from patients who received health check-up services as part of an employer-provided wellness program performed between August 2006 and May 2008 and who were followed up for 12-24 mo. Prior to screening colonoscopy, 224 patients underwent bowel cleansing with NaP (NaP group) and 113 patients with polyethylene glycol (PEG group). The control group comprised 672 age-matched patients. We compared the changes in the creatinine levels and the glomerular filtration rates (GFRs) from baseline to 12-24 mo between the NaP, PEG, and control groups using two-way repeated measured analysis of variance. In addition, multivariate linear regression analysis was performed to assess the risk factors for a decreased GFR.RESULTS: The baseline mean serum creatinine level in the NaP, PEG, and control groups was 1.12 ± 0.15, 1.12 ± 0.16, and 1.12 ± 0.15 mg/dL, which increased to 1.15 ± 0.15, 1.15 ± 0.18, and 1.15 ± 0.15 mg/dL, respectively, after 12-24 mo. The baseline mean GFR in the NaP, PEG, and control groups was 69.0 ± 7.7, 68.9 ± 8.0, and 69.6 ± 6.7 mL/min per 1.73 m2, which decreased to 66.5 ± 7.8, 66.5 ± 8.3, and 67.4 ± 6.4 mL/min per 1.73 m2, respectively, after 12-24 mo. The changes in serum creatinine levels and GFRs were not significantly between the NaP, PEG, and control groups (P = 0.992 and P = 0.233, respectively). Using multivariate linear regression analysis, only the baseline GFR was associated with the change in GFR (P < 0.001). Indeed, the bowel preparations were not associated with the change in GFR (P = 0.297).CONCLUSION: NaP bowel preparation in subjects with normal renal function was not associated with renal injury, and NaP can thus be used safely for screening colonoscopy.
Distributed and Parallel Big Textual Data Parsing for Social Sensor Network
Jung-Ho Um,Chang-Hoo Jeong,Sung-Pil Choi,Seungwoo Lee,Hwan-Min Kim,Hanmin Jung
International Journal of Distributed Sensor Networks , 2013, DOI: 10.1155/2013/525687
Abstract: Recently, due to the popularization of the smartphone and social network service (SNS), many SNS users write their opinions for social events. According to these social phenomena, social sensor network which analyzes social events by utilizing those users’ text data is proposed. Parsing is essential module to analyze user’s text contents because it gives the understanding of semantics by extracting the words and their classes from texts. However, parsing requires much time because it needs to analyze all context information from the users’ text. In addition, as users’ text data are generated and transferred in streaming, the required parsing time increases too. This situation occurs that it is hard to parse the text on the single machine. Therefore, to drastically enhance the parsing speed, we propose distributed and parallel parsing system on the MapReduce. It applies the legacy parser to the MapReduce through loose coupling. Also, to reduce communication overheads, the statistical model used by the parser is resided on local cache in each mapper. The experimental result shows that the speed of proposed system is 2–19 times better than that of the legacy parser. As a result, we prove that the proposed system is useful for parsing text data in social sensor network. 1. Introduction Currently, as a result of the development of smartphone device techniques and active use of the social network service (SNS), many people use SNS smartphone applications. In the United States, there are 30 million smartphone users in 2011 and had increased by million users per week in the last quarter of 2012 (http://tech.fortune.cnn.com/2012/03/07/u-s-smartphones-inching-toward-1-million-per-week/). In addition, Twitter, a representative SNS provider, has about 50 million cases of uploading per day and FaceBook, another provider, has about 60 million cases of uploading (http://allfacebook.com/twitter-facebook-status_b11613). Smartphone users post writings about their daily life or share major social events or issues using SNS such as Twitter, Facebook, U-tube, and flicker. Many studies have been made to find out social issues or to solve scientific problems through these smartphone users’ big text data [1–11]. For example, to detect radiation values generated by the japan’s Fukushima Daiichi nuclear disaster, crowd sourced real-time radiation maps are developed by providing detecting radiation information from the smart-phone users. Another example is constructing the citizen sensor network for the scientific discovery by offering volunteers’ location information with their
Characteristics of Mesenchymal Stem Cells Originating from the Bilateral Inferior Turbinate in Humans with Nasal Septal Deviation
Se Hwan Hwang, Sun Hwa Park, Jin Choi, Dong Chang Lee, Jeong Hoon Oh, Sung Won Kim, Jin Bae Kim
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0100219
Abstract: Background and objectives Nasal septal deviation (NSD) is often associated with overgrowth of the unilateral inferior turbinate. In vivo and in vitro studies indicate that human mesenchymal stem cells (MSCs) are able to differentiate into multiple cell types, including osteoblasts. We tested the hypothesis that turbinate size affects human turbinate-derived MSC (hTMSCs) quantity, proliferation, and differentiation into osteogenic lineages, and that hypertrophic turbinates may predispose to NSD on the contralateral side. Subjects and Methods The hypertrophic and contralateral inferior turbinate tissues used in our study were obtained and cultured from the tissue discarded from 10 patients who underwent septoplasty and partial turbinectomy. After isolating the hTMSCs from both turbinates, the cells were enumerated using an automated cell counter. The expression of surface markers for MSCs over four passages was assessed by fluorescent-activated cell sorting analysis (FACS), and cell proliferation was assessed using a cell counting kit (CCK)-8 according to turbinate size. In addition, osteogenic differentiation of hTMSCs was identified using alkaline phosphatase (ALP) and alizarin red S staining, after which osteoblastic gene expression was evaluated. Results There was no significant difference in the number of hTMSCs. FACS analysis revealed that the hTMSCs were negative for CD14, CD19, CD34, and HLA-DR, and positive for CD29, CD73, and CD90, representing a characteristic MSC phenotype, with no significant difference between the two groups. The cellular proliferation and osteogenic differentiation potential of the hTMSCs were also not significantly different between the two groups. Conclusions We conclude that turbinate size does not affect the characterization, proliferation, and osteogenic differentiation potential of hTMSCs in vitro test, and therefore should not affect the clinical decision of whether to use autologous or allogenic hTMSCs. However, more experiments are required to definitively state the relationship of hTMSCs with turbinate size or the process NSD in humans.
Development of a hybrid scaffold and a bioreactor for cartilage regeneration
Seung-Jae Lee,In Hwan Lee,Jeong Hun Park,So-Jung Gwak,Jong-Won Rhie,Dong-Woo Cho,Tae Jo Ko,Dong Sung Kim
Chinese Science Bulletin , 2009, DOI: 10.1007/s11434-009-0602-8
Abstract: We developed a hybrid scaffold and a bioreactor for cartilage regeneration. The hybrid scaffold was developed as combination of two components: a biodegradable framework and hydrogel-containing chondrocytes. We performed the MTT cell proliferation assay to compare the proliferation and viability of chondrocytes on three types of scaffolds: an alginate gel, the hybrid scaffold, and an alginate sponge. Cells were encapsulated in 2% agarose gel. The bioreactor consisted of a circulation system and a compression system. We performed dynamic cell culture on these agarose gels in the bioreactor for 3 days.
Importance of the surrounding colonic mucosa in distinguishing between hyperplastic and adenomatous polyps during acetic acid chromoendoscopy
Jeong Hwan Kim, Sun-Young Lee, Byung Kook Kim, Won Hyeok Choe, So Young Kwon, In-Kyung Sung, Hyung-Seok Park, Choon-Jo Jin
World Journal of Gastroenterology , 2008,
Abstract: AIM: To examine the characteristics of colonic polyps, where it is difficult to distinguish adenomatous polyps from hyperplastic polyps, with the aid of acetic acid chromoendoscopy.METHODS: Acetic acid spray was applied to colonic polyps smaller than 10 mm before complete excision. Endoscopic images were taken before and 15-30 s after the acetic acid spray. Both pre- and post-sprayed images were shown to 16 examiners, who were asked to interpret the lesions as either hyperplastic or adenomatous polyps. Regression analysis was performed to determine which factors were most likely related to diagnostic accuracy.RESULTS: In 50 cases tested by the 16 examiners, the overall accuracy was 62.4% (499/800). Regression analysis demonstrated that surrounding colonic mucosa was the only factor that was significantly related to accuracy in discriminating adenomatous from hyperplastic polyps (P < 0.001). Accuracy was higher for polyps with linear surrounding colonic mucosa than for those with nodular surrounding colonic mucosa (P < 0.001), but was not related to the shape, location, or size of the polyp.CONCLUSION: The accuracy of predicting histology is significantly related to the pattern of colonic mucosa surrounding the polyp. Making a histological diagnosis of colon polyps merely by acetic acid spray is helpful for colon polyps with linear, regularly patterned surrounding colonic mucosa, and less so for those with nodular, irregularly patterned surrounding colonic mucosa.
Age-Related Characteristics of Multipotent Human Nasal Inferior Turbinate-Derived Mesenchymal Stem Cells
Se Hwan Hwang, Sun Hwa Park, Jin Choi, Dong Chang Lee, Jeong Hoon Oh, Un Cheol Yeo, Sung Won Kim, Dong Il Sun
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0074330
Abstract: Background and Objectives Multipotent mesenchymal stem cells (MSCs) represent a promising cell-based therapy for a number of degenerative conditions. Understanding the effect of aging on MSCs is crucial for both autologous therapy development and allogenic donors in older subjects whom degenerative diseases typically afflict. In this study, we investigated the influence of donor age on the characteristics, proliferation, and differentiation potential of in vitro cultures of multipotent human turbinated mesenchymal stem cells (hTMSCs) from patients of various age groups. Subjects and Methods Twelve patients comprised the four age groups: (I) <20 years, (II) 20–39 years, (III) 40–59 years, and (IV) >60 years. Inferior turbinate tissues were discarded from patients undergoing partial turbinectomy. After isolating hTMSCs, the expression of the hTMSC surface markers CD14, CD19, CD34, CD73, CD90, CD105, and HLA-DR was assessed by FACS analysis, and cell proliferation was assessed using a cell counting kit (CCK)-8. The differentiation potential of hTMSCs was evaluated in osteogenic media by histology and determination of osteoblastic gene expression. Results FACS analysis revealed that hTMSCs were negative for CD14, CD19, CD34, and HLA-DR, and positive for CD73, CD90, and CD105, representing a characteristic MSC phenotype, and showed no significant differences among the age groups. Cellular proliferation and osteogenic differentiation potential of hTMSCs also showed no significant differences among the age groups. Conclusions We conclude that donor age does not affect the characteristics, proliferation, and osteogenic differentiation potential of hTMSCs. Donor age may be excluded as a criterion in the guidelines for clinical use of the autologous or allogenic transplantation of hTMSCs.
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