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Search Results: 1 - 10 of 30467 matches for " Sui-Qing Cai "
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Role of VEGF Receptors in Normal and Psoriatic Human Keratinocytes: Evidence from Irradiation with Different UV Sources
Jian-Wei Zhu, Xian-Jie Wu, Zhong-Fa Lu, Dan Luo, Sui-Qing Cai, Min Zheng
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0055463
Abstract: Vascular endothelial growth factor (VEGF) promotes angiogenesis and plays important roles both in physiological and pathological conditions. VEGF receptors (VEGFRs) are high-affinity receptors for VEGF and are originally considered specific to endothelial cells. We previously reported that VEGFRs were also constitutively expressed in normal human keratinocytes and overexpressed in psoriatic epidermis. In addition, UVB can activate VEGFRs in normal keratinocytes, and the activated VEGFR-2 signaling is involved in the pro-survival mechanism. Here, we show that VEGFRs were also upregulated and activated by UVA in normal human keratinocytes via PKC, and interestingly, both the activated VEGFR-1 and VEGFR-2 protected against UVA-induced cell death. As VEGFRs were over-expressed in psoriatic epidermis, we further investigated whether narrowband UVB (NB-UVB) phototherapy or topical halomethasone monohydrate 0.05% cream could affect their expression. Surprisingly, the over-expressed VEGFRs in psoriatic epidermis were significantly attenuated by both treatments. During NB-UVB therapy, VEGFRs declined first in the basal, and then gradually in the upper psoriatic epidermis. VEGFRs were activated in psoriatic epidermis, their activation was enhanced by NB-UVB, but turned undetectable after whole therapy. This process was quite different from that by halomethasone, in which VEGFRs and phospho-VEGFRs decreased in a gradual, homogeneous manner. Our findings further suggest that UV-induced activation of VEGFRs serves as a pro-survival signal for keratinocytes. In addition, VEGFRs may be involved in the pathological process of psoriasis, and UV phototherapy is effective for psoriasis by directly modulating the expression of VEGFRs.
rDNA ITS Sequence Analysis of Different Cultivar Variety of Cornus officinalis
山茱萸不同栽培品种的rDNA ITS序列分析

CHEN Sui-Qing,PAN Cheng-Xue,LU Xiao-Lei,WANG Li-Li,

植物科学学报 , 2010,
Abstract: To study rDNA ITS sequence of Cornus officinalis Sieb.et.Zucc.,and analyzed the rDNA ITS sequence of its different cultivated varieties.A pair of primers was selected by experiment.The ITS gene fragment was amplified using this pair of primers,and PCR products were purified with DNA gel extraction kit(AxyPrepTM)and sequenced by the method of Sanger dideoxy.Then the ITS1-5.8S-ITS2 sequences were analyzed by the software of DNAssist Version 2.0.The ITS1-5.8S-ITS2 sequences was found whole ITS sequence consist...
Mineralization of BPA by Combination of UV/HO/Micro-Aeration Process

HU Ling,GAO Nai-yun,XU Bin,LI Ruo-yu,ZHAO Jian-fu,LIU Sui-qing,

环境科学 , 2007,
Abstract: The degradation and mineralization of bisphenol A(BPA) in water by UV/H2O2/micro-aeration process were investigated. UV/H2O2/ micro-aeration is a new process developing from UV/H2O2. A quantity of ozone appears when both micro-aeration and UV radiation exist, which enhances the productive rate of *OH. The effects of intensity of UV radiation, dosages of H2O2 and initial pH of the solution on mineralization of BPA by UV/H2O2/micro-aeration process were studied. The results show that the mineralization rate of BPA increases linearly with the enhancement of intensity of UV radiation. When the dosages of H2O2 change from 5 mg/L to 20 mg/L, the constant (k) of mineralization rate rises from 0.003 2 to 0.025 0. While pH is 6.68, it can get the best effect of mineralization. Under the same conditions the mineralization rate is much higher than its degradation rate. It's found that BPA is first degraded into smaller molecular organic matters, and the small molecular organic matters are further mineralized into inorganic matters gradually.
Effect of Chlorine on PAC''s Ability to Adsorb Microcystin

LIU Cheng,GAO Nai-yun,DONG Bing-zhi,LIU Sui-qing,ZHAO Jian-fu,

环境科学 , 2007,
Abstract: Bottle-point experiments were conducted in Huangpu river raw water to examine the extent to which chlorine influenced the ability of powdered activated carbon (PAC) to adsorb two kinds of microcystins (MC-RR and MC-LR). The result shows that,when adding PAC and chlorine at the same point, chlorine can enhance the removal effect of the combined process (about 20%), which may be because the surface of PAC catalyzes the reaction between mirocystin and chlorine molecule, when adding PAC and chlorine at different points, the strengthening effect disappear chlorine reduces the ability of PAC to microcystins to some extent (5%-10%)], the effect of chlorine to PAC becomes weak when raise the dosage of PAC. PAC can effectively remove microcystins (the removal effect can reach 55% and 45% for MC-RR and MC-LR respectively at the dosage of 10 mg/L, contact time of 6 hours) when using PAC alone.
Breakthrough Characteristics of Dimethyl Phthalate in Granular Activated Carbon

SUN Xiao-feng,GAO Nai-yun,XU Bin,LIU Sui-qing,ZHAO Jian-fu,NING Ran,

环境科学 , 2007,
Abstract: 在25℃条件下,研究了颗粒活性炭(GAC)对水中邻苯二甲酸二甲酯(DMP)的动态吸附特性及其影响因素.在不同进水流量(0.65~4 mL·min-1)、GAC粒径(550~1 250 μm)、DMP初始浓度(50~400 mg·L-1)和GAC炭量(0.75~1.4 g)条件下,考察了DMP在GAC柱中的穿透特性.研究表明,GAC对DMP的吸附容量较大,Yoon-Nelson模型能够很好地拟合各种工况下的动态穿透曲线;动态吸附容量随着进水流量和GAC粒径的增大而减小,相反,随着DMP初始浓度和GAC炭量的增大而增大.根据试验数据和Yoon-Nelson模型计算出穿透参数K′、T和穿透点t1以及平衡点t2.在建立了各影响因素与Yoon-Nelson穿透模型参数之间的关系基础上,得到了活性炭柱出水浓度与穿透时间和各影响因素之间的动态关系模型.
Kinetics of Endocrine Disrupting Chemical 4-tert-butylphenol During Chlorination in Aqua

SUN Xiao-feng,GAO Nai-yun,XU Bin,WANG Xue-jiao,NING Ran,LIU Sui-qing,

环境科学 , 2007,
Abstract: The kinetics of endocrine disruptor 4-tert-butylphenol by chlorination in aqua was studied. The results showed that 4-TBP was rapidly oxidized by chlorine with different initial concentrations of HOCl and pH, and second-order reaction kinetics was observed between 4-TBP and chlorine. The apparent kinetic rate constants were influenced by pH values, kapp reached its highest and lowest level at pH 5 and 9 respectively. The kinetic rate constant of every elementary reaction was calculated. The rate constants for the acid-catalyzed reaction and the reaction between between ClO- and4-TBP were 4.99×106 L2?mol-2?s-1 and 1.96×104L?(mol?s)-1 respectively. The reaction between HOCl and 4-TBP or HOCl and 4-TBP- was very slow, and ClO- did not react with 4-TBP-. 4-TBP was influenced by chlorine disinfection during water treatment. The corresponding half-life times was 12.1min when chlorine concentration was 3 mg/L.
The Research of Chinese College Student Cadres’ Leadership Style Based on the Contingency Theory  [PDF]
Liangtie Dai, Qing Cai
Journal of Human Resource and Sustainability Studies (JHRSS) , 2014, DOI: 10.4236/jhrss.2014.24025
Abstract: This article is written from the view of contingency theory. It analyses the types of Chinese college student cadres’ leadership style and the types’ connection with gender, organization functions and performance. At the same time, it explores the most suitable style for the college student organization, and hopes to provide some relevant recommendations to higher education’s talent cultivation.
Rheological Behaviors of Bio-degradable Drilling Fluids in Horizontal Drilling of Unconsolidated Coal Seams
Cai Jihua,Gu Sui
International Journal of Information Technology and Computer Science , 2011,
Abstract: In China, horizontal drilling techniques have been widely used in the exploration of coalbed methane (CBM). The drill-in fluids, especially in unconsolidated coal seams, are typically comprised of cellulose polymers, xanthan polymers and guar gums. However, testing and experience have shown that insufficient degradation of filter cakes resulting from even this “clean” drill-in fluids can significantly impede flow capacity at the wellbore wall. Past approaches to minimizing the damage have been the application of strong acids or oxidative breakers systems. They are often only marginally successful, particularly when applied in extended length intervals. Therefore, this paper introduced an engineered technique incorporating non-toxic, environment friendly and economically attractive bio-degradable drilling fluids (BDF).Extensive lab tests were conducted to evaluate the effects of substrate (polymer) type, substrate concentration, enzyme type and enzyme concentration on the viscosity breaking behaviors of BDFs. We got the conclusions as follows. (1) Power Law model was the best model to matching the rheological properties of BDFs; (2) Compared with konjak, the degradations of Na-CMC and guar gum were easier to be controlled; (3) In the degradation of CMC by enzyme SE-1, the optimal weight concentration ratio of CMC to SE-1 was 3 to 1; (4) Of the three enzymes, enzyme SE-2 had the highest activity and could be used to degrade polymer in shorter time; (5) Higher enzyme concentration could speed up the degradation reaction; (6) Viscosity breaking times fluctuating from 13.5 hours to 74.5 hours and viscosity breaking ratios varying from 20% to 100% could be achieved by modifying the formulations of BDFs.
Resveratrol Inhibits Invasion and Metastasis of Colorectal Cancer Cells via MALAT1 Mediated Wnt/β-Catenin Signal Pathway
Qing Ji, Xuan Liu, Xiaoling Fu, Long Zhang, Hua Sui, Lihong Zhou, Jian Sun, Jianfeng Cai, Jianmin Qin, Jianlin Ren, Qi Li
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0078700
Abstract: Resveratrol, extracted from Chinese herbal medicine Polygonum cuspidatum, is known to inhibit invasion and metastasis of human colorectal cancer (CRC), in which long non-coding Metastasis Associated Lung Adenocarcinoma Transcript 1 (RNA-MALAT1) also plays an important role. Using MALAT1 lentiviral shRNA and over-expression constructs in CRC derived cell lines, LoVo and HCT116, we demonstrated that the anti-tumor effects of resveratrol on CRC are through inhibiting Wnt/β-catenin signaling, thus the expression of its target genes such as c-Myc, MMP-7, as well as the expression of MALAT1. In detail, resveratrol down-regulates MALAT1, resulting in decreased nuclear localization of β-catenin thus attenuated Wnt/β-catenin signaling, which leads to the inhibition of CRC invasion and metastasis. This finding of ours surely provides important pre-clinical evidence supporting future use of resveratrol in prevention and treatment of CRC.
A study of hyperfine structure of B and Fe interaction in high-boron steel

Chen Sui-Yuan,Liu Chang-Sheng,Fu Gui-Qin,Wang Zhang-Tao,Cai Qing-Kui,

物理学报 , 2002,
Abstract: 采用真空感应熔炼的方法制备出含B量为0.15%—0.55%的低合金钢.通过X射线衍射技术和穆斯堡尔谱分析技术,研究了其中B与Fe元素作用的微结构.确定了穆斯堡尔谱的基本参量———化学位移(IS)、四极分裂(QS)、内磁场(Hhf)随高硼钢成分变化的规律.研究结果表明,B元素少部分固溶在αFe中,大部分与Fe形成Fe2B和FeB.分析了B和Fe原子核外电子结构的变化特征及超精细结构变化的原因
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