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Search Results: 1 - 10 of 461831 matches for " Suha A. Fataftah "
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Pediatric Non-Hodgkin Lymphoma: A Retrospective 7-Year Experience in Children & Adolescents with Non-Hodgkin Lymphoma Treated in King Fahad Medical City (KFMC)  [PDF]
Nahla Ali Mobark, Suha A. Tashkandi, Wafa Al Shakweer, Khalid Al Saidi, Suha A. Fataftah, Mohammed M. Al Nemer, Awatif Alanazi, Mohammed Rayis, Walid Ballourah, Othman Mosleh, Zaheer Ullah, Fahad El Manjomi, Musa Al Harbi
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.64033
Abstract:

Background: Non-Hodgkin’s lymphoma is an aggressive malignant disease in children and adolescents. Although it is the fourth most common malignancy in Saudi children as reported in Saudi cancer registry, less information is available about pediatric Non-Hodgkin lymphoma and its outcome in Saudi Arabia. Study Objectives: To provide demographic data, disease characteristics, treatment protocol, toxicity and outcome of treatment in children & adolescents with Non-Hodgkin’s lymphoma treated at KFMC. This study will form base line for future studies about pediatric Non-Hodgkin’s lymphoma in KFMC, which may help to improve outcome for children with cancer in Saudi Arabia. Study Patients and Method: We retrospectively analyzed 28 children and adolescents diagnosed to have Non-Hodgkin’s lymphoma at KFMC between December 2006 and December 2013, followed-up through June 2014. Results: Of the 28 patients, 10 (35.7%) girls and 18 (64.3%) boys, the male-to-female ratio was 1.8; 1. The median age at time of diagnosis was 6.4 years old (range 2.0 to 13.0 years old). The majority of patients (64.3%) were aged between 5 and 12 years old. Burkitt’s lymphoma BL/BLL was the most common pathological subtype (60.7%), and DLBCL was the second most common subtype (21.4%). Abdominal and Retroperitoneal involvement was the most common primary site (78.6%) including the ileocaecal region. Most of the children presented with advanced Stage III and IV (75%), Cytogenetic study which screens specifically for the t (8; 14) (q24; q32) a characteristic genetic feature of Burkitt’s Lymphoma was obtained from 21 patients, variant rearrangement was observed in 3/21 samples and complex chromosomes karyotype in addition to IGH/MYC rearrangement was observed in 2/21 samples. Those patients presented with very aggressive lymphoma and combined BM and CNS involvement. We use the French-American-British Mature B-Cell Lymphoma 96 Protocol (FAB LMB 96) for treatment fornewly diagnosed Mature B-Cell type NHL and high risk ALL CCG 1961 Protocol for lymphoblastic lymphoma and international Anaplastic Large Cell Lymphoma 99 Study Protocol for ALCL. The median follow-up in patients not experiencing an adverse event was 53.1 months. The estimated 3-year EFE and OS rates in the entire cohort of patients with newly diagnosed NHL treated in the KFMC were 85.2% and 89.2% respectively; Overall survival (OS) rate of patients with mature

Cultural Sensitivity of a Community-Based Falls Prevention Program Targeting Older Arab American  [PDF]
Lan Yao, Suha A. Kridli
Open Journal of Nursing (OJN) , 2018, DOI: 10.4236/ojn.2018.811063
Abstract: Falls are a frequent and costly cause of injuries and functional decline in the elderly. Tai Chi is a cost-effective strategy for preventing falls in older adults. Many senior centers have introduced Tai Chi programs to increase mobility and decrease the risk of falls. However, the practice has yet to be widely disseminated to ethnic minorities who are not culturally connected to Tai Chi. This paper describes implementation barriers and recruitment and retention challenges of Arab American participants in a Tai Chi intervention-based health promotion program, including issues related to community organization and staffing, recruitment and retention, need for building relationships, need for translation and interpreters, and cultural barriers & misconceptions. Understanding and paying adequate attention to these challenges may help facilitate in planning other health promotion interventions targeting Arab American population.
Fluorescence Technique Description for Measuring Ca2+ in Mice Sperm  [PDF]
Suha Mahmood A. Alghazal, Jiuping Ding
Advances in Molecular Imaging (AMI) , 2015, DOI: 10.4236/ami.2015.52003
Abstract: Recently, fluorescence technique becomes very useful. It can allow for addressing a fundamental problem of cellular mechanism besides characterizing the species inside the cell to facilitate the diagnostic and prognostic value. Manipulation with fluorescent dyes provides many possibilities for their use as tags, probes, and sensors. These types can be intrinsic or extrinsic to the cell. They can become not only silent observers, but also participants, modulators or disruptors of specific activities outline the biological functions can be successfully studied quantitatively and qualitatively with fluorescence techniques.
Zappa-Szép Products of Semigroups  [PDF]
Suha Wazzan
Applied Mathematics (AM) , 2015, DOI: 10.4236/am.2015.66096
Abstract: The internal Zappa-Szép products emerge when a semigroup has the property that every element has a unique decomposition as a product of elements from two given subsemigroups. The external version constructed from actions of two semigroups on one another satisfying axiom derived by G. Zappa. We illustrate the correspondence between the two versions internal and the external of Zappa-Szép products of semigroups. We consider the structure of the internal Zappa-Szép product as an enlargement. We show how rectangular band can be described as the Zappa-Szép product of a left-zero semigroup and a right-zero semigroup. We find necessary and sufficient conditions for the Zappa-Szép product of regular semigroups to again be regular, and necessary conditions for the Zappa-Szép product of inverse semigroups to again be inverse. We generalize the Billhardt λ-semidirect product to the Zappa-Szép product of a semilattice E and a group G by constructing an inductive groupoid.
FT-ICR/MS and GC-EI/MS Metabolomics Networking Unravels Global Potato Sprout's Responses to Rhizoctonia solani Infection
Konstantinos A. Aliferis, Suha Jabaji
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0042576
Abstract: The complexity of plant-pathogen interactions makes their dissection a challenging task for metabolomics studies. Here we are reporting on an integrated metabolomics networking approach combining gas chromatography/mass spectrometry (GC/MS) with Fourier transform ion cyclotron resonance/mass spectrometry (FT-ICR/MS) and bioinformatics analyses for the study of interactions in the potato sprout-Rhizoctonia solani pathosystem and the fluctuations in the global metabolome of sprouts. The developed bioanalytical and bioinformatics protocols provided a snapshot of the sprout's global metabolic network and its perturbations as a result of pathogen invasion. Mevalonic acid and deoxy-xylulose pathways were substantially up-regulated leading to the biosynthesis of sesquiterpene alkaloids such as the phytoalexins phytuberin, rishitin, and solavetivone, and steroidal alkaloids having solasodine and solanidine as their common aglycons. Additionally, the perturbation of the sprout's metabolism was depicted in fluctuations of the content of their amino acids pool and that of carboxylic and fatty acids. Components of the systemic acquired resistance (SAR) and hypersensitive reaction (HR) such as azelaic and oxalic acids were detected in increased levels in infected sprouts and strategies of the pathogen to overcome plant defense were proposed. Our metabolic approach has not only greatly expanded the multitude of metabolites previously reported in potato in response to pathogen invasion, but also enabled the identification of bioactive plant-derived metabolites providing valuable information that could be exploited in biotechnology, biomarker-assisted plant breeding, and crop protection for the development of new crop protection agents.
On the First and Second Locating Zagreb Indices of Graphs  [PDF]
Suha A. Wazzan, Anwar Saleh
Applied Mathematics (AM) , 2019, DOI: 10.4236/am.2019.1010057
Abstract: By the distance or degree of vertices of the molecular graph, we can define graph invariant called topological indices. Which are used in chemical graph to describe the structures and predicting some physicochemical properties of chemical compound? In this paper, by introducing two new topological indices under the name first and second Zagreb locating indices of a graph G, we establish the exact values of those indices for some standard families of graphs included the firefly graph.
Oxidative stress parameters in blood and urine of metal-shelf factory workers
Naci POLAT,Ahmet KILIN?,A. Suha YAL?IN
Marmara Medical Journal , 2013,
Abstract: Objectives: We have investigated the level of antioxidants (glutathione (GSH), GSH-reductase, GSH-peroxidase, GSHtransferase, catalase (CAT) and superoxide dismutase (SOD)), lipid peroxidation products (plasma, erythrocyte and urinary malondialdehyde (MDA)) and urinary DNA damage product 8-hydroxydeoxyguanosine (8-OH-2’-dG) in metal-shelf factory workers and compared the levels to those of a control group working in a different work area.Methods: Twenty four workers working in a metal shelf production factory and sixteen apparently healthy male volunteers without environmental and work place exposure were included in the study. Blood and urine samples were examined for oxidative stress parameters. Measurement of 8-OH-2’-dG was by high performance liquid chromatography (HPLC), while other parameters were measured by colorimetric methods.Results: GSH-transferase , CAT, SOD activities and plasma, erythrocyte and urinary MDA levels of metal shelf production factory workers were higher than for the control group, whereas, GSH-peroxidase and GSH in workers were lower than for controls. Moreover, while GSH-reductase activity was lower, 8-OH-2’-dG level was higher than the control group but the difference was not statistically significant.Conclusion: As a result of increased industrialization, air pollution and hazardous working conditions there is a deterioration of the balance between oxidant and antioxidant levels which affects the structure of macromolecules such as DNA, lipids and proteins.
Sonographic Evaluation of Obstructive Jaundice  [PDF]
Moawia Gameraddin, Suzan Omer, Suliman Salih, Suha A. Elsayed, Abdalmonem Alshaikh
Open Journal of Medical Imaging (OJMI) , 2015, DOI: 10.4236/ojmi.2015.51004
Abstract: Purpose: This study was done to assess the role of ultrasound in diagnosis of obstructive jaundice and to identify the most common causes and symptoms. Materials and methods: The study took place in different Khartoum clinical centers and hospitals in the period between Jan 2014 and July 2014. A total of 150 patients with obstructive jaundice were examined using ultrasound machine, 3.5 - 7 MHz probe. Results: The study revealed that 65.33 of the study population with obstructive jaundice were female and 34.67% was male. The most common affected groups were 46 - 65 years old and 25 - 45 years old. The common causes of obstructive jaundice were biliary stones (61.33%) which were common in females and abdominal masses (32.67%) which were common in females, too. Nausea, yellowish discoloration and abdominal pain were the most common symptoms (98%, 97.33% and 96.67% respectively). The causes of obstructive jaundice showed significant difference between males and females (P-value = 0.002). Conclusion: Ultrasound was superior diagnostic tool in detecting and assessing biliary system obstruction, because it was easy, available, accurate and noninvasive. The ageing and gender were considered as risk factors of obstructive jaundice.
Transmission Characteristic Simulation of High Frequency Acousto-Optic Modulators  [PDF]
Suha Mousa Alawsi, Lubaba Abdul Kareem Al-Janabi, Soror A. Mahdi
Optics and Photonics Journal (OPJ) , 2018, DOI: 10.4236/opj.2018.84010
Abstract: The way by which one can make sure the operating mode of the modulation is by observing the Comsol results of the designed model of proposed acousto-optic modulator (AOM). These results include the pressure distribution, sound pressure distribution, stress distribution at piezoelectric, far-field analysis that describes the diffracted light orders, and electric potential versus light frequency. Throughout the simulating process of modulator operating using Comsol, it begins when the RF is power by a voltage of 100 V, the light is then split into first ordered diffraction, which implies that the modulator is in the operating mode. The use of semiconductor materials is due to its smaller gap that easily transfers the energy that leads to generating first order diffraction when they provided a voltage power. It mentioned that zero order diffraction indicates the modulator does not run; other orders are appearing with increasing the frequency of light leading to decrease of the efficiency of the modulator performance.
PREPARATION OF LIPOSOMES CONTAINING WHEY PROTEINS
A. Suha Yal??n,Murat Türko?lu
Marmara Medical Journal , 2010,
Abstract: Aim: In recent years, it has been shown that whey and its components have a number of health-promoting effects. We aimed to isolate fractions containing whey proteins using chromatography and then to prepare antioxidant liposomes in order to obtain a gel suitable for cosmetic preparations.Methods: Fractionation of whey proteins was achieved by extraction, filtration and centrifugation followed by liquid chromatography. The antioxidant activities of the fractions was determined by their copper ion reducing capacity. Gel electrophoresis was used to analyze the proteins. Liposomes were made by the thin film hydration method.Results and Conclusion: Using Sephadex G-50 chromatography, two fractions were obtained. The first fraction contained major whey proteins, while the second fraction had small peptides. We have then determined the antioxidant activities of these fractions. The first fraction had the highest antioxidant activity. We prepared liposomes containing whey protein fractions and analyzed their sizes. Then, we investigated the liposome structures under a light microscope, electron microscope and atomic force microscope. Finally, we prepared a cosmetic formula from liposomes containing the whey fractions. We believe that preparing antioxidant liposomes containing whey proteins will be an important contribution to the cosmetic formulas for dermal applications.
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